| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Dai, K Gebhardt, R J Care. Time course effects of MK-801: the relationship between brain neurochemistry and behavior. Brain research bulletin. vol 36. issue 2. 1995-04-24. PMID:7534612. |
serotonin metabolism was unaffected in striatum or medial prefrontal cortex across all injection intervals, and there was no effect of mk-801 on plasma corticosterone levels. |
1995-04-24 |
2023-08-12 |
rat |
| S Jordan, G L Kramer, P K Zukas, M Moeller, F Pett. In vivo biogenic amine efflux in medial prefrontal cortex with imipramine, fluoxetine, and fluvoxamine. Synapse (New York, N.Y.). vol 18. issue 4. 1995-04-10. PMID:7886621. |
in vivo brain microdialysis was used to determine the effects of the standard tricyclic antidepressant imipramine and the two selective serotonin reuptake inhibitors (ssris) antidepressants, fluoxetine and fluvoxamine, on extracellular levels of norepinephrine (ne), dopamine (da), and serotonin (5-ht) in rat medial prefrontal cortex. |
1995-04-10 |
2023-08-12 |
rat |
| A M Rasmusson, L E Goldstein, A Y Deutch, B S Bunney, R H Rot. 5-HT1a agonist +/-8-OH-DPAT modulates basal and stress-induced changes in medial prefrontal cortical dopamine. Synapse (New York, N.Y.). vol 18. issue 3. 1995-03-14. PMID:7855734. |
however, at a dose of 225 micrograms/kg, +/-8-oh-dpat significantly increased basal dopamine utilization and release in the medial prefrontal cortex, while simultaneously decreasing serotonin release in this area. |
1995-03-14 |
2023-08-12 |
human |
| R J Carey, E N Damianopoulo. Conditioned cocaine induced hyperactivity: an association with increased medial prefrontal cortex serotonin. Behavioural brain research. vol 62. issue 2. 1994-12-07. PMID:7945968. |
conditioned cocaine induced hyperactivity: an association with increased medial prefrontal cortex serotonin. |
1994-12-07 |
2023-08-12 |
rat |
| B K Yamamoto, E A Pehek, H Y Meltze. Brain region effects of clozapine on amino acid and monoamine transmission. The Journal of clinical psychiatry. vol 55 Suppl B. 1994-11-28. PMID:7961581. |
chronic treatment with clozapine increased dopamine and serotonin in the medial prefrontal cortex. |
1994-11-28 |
2023-08-12 |
rat |
| F Petty, G Kramer, M Moelle. Does learned helplessness induction by haloperidol involve serotonin mediation? Pharmacology, biochemistry, and behavior. vol 48. issue 3. 1994-11-04. PMID:7938121. |
haloperidol (ip) increased release of serotonin (5-ht) in medial prefrontal cortex (mpc) as measured by in vivo microdialysis. |
1994-11-04 |
2023-08-12 |
rat |
| C R Ashby, J Y Zhang, E Edwards, R Y Wan. The induction of serotonin3-like receptor supersensitivity and dopamine receptor subsensitivity in the rat medial prefrontal cortex after the intraventricular administration of the neurotoxin 5,7-dihydroxytryptamine: a microiontophoretic study. Neuroscience. vol 60. issue 2. 1994-09-23. PMID:8072691. |
our results indicate that 5,7-dihydroxytryptamine-induced denervation selectively enhances the sensitivity of serotonin3-like receptors in the medial prefrontal cortex, which could, at least partially, account for the serotonin denervation supersensitivity. |
1994-09-23 |
2023-08-12 |
rat |
| C R Ashby, J Y Zhang, E Edwards, R Y Wan. The induction of serotonin3-like receptor supersensitivity and dopamine receptor subsensitivity in the rat medial prefrontal cortex after the intraventricular administration of the neurotoxin 5,7-dihydroxytryptamine: a microiontophoretic study. Neuroscience. vol 60. issue 2. 1994-09-23. PMID:8072691. |
moreover, the finding that the response of medial prefrontal cortical cells to the iontophoresis of dopamine is attenuated in 5,7-dihydroxytryptamine pretreated rats is consistent with the view that the inhibitory action of dopamine in the medial prefrontal cortex is dependent upon serotonin tone. |
1994-09-23 |
2023-08-12 |
rat |
| L E Goldstein, A M Rasmusson, B S Bunney, R H Rot. The NMDA glycine site antagonist (+)-HA-966 selectively regulates conditioned stress-induced metabolic activation of the mesoprefrontal cortical dopamine but not serotonin systems: a behavioral, neuroendocrine, and neurochemical study in the rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 8. 1994-08-30. PMID:8046462. |
this effect was also neurochemically specific since the stress-induced increase in 5-ht utilization in the medial prefrontal cortex was not affected by (+)-ha-966 pretreatment. |
1994-08-30 |
2023-08-12 |
human |
| E J Van Bockstaele, A Biswas, V M Picke. Topography of serotonin neurons in the dorsal raphe nucleus that send axon collaterals to the rat prefrontal cortex and nucleus accumbens. Brain research. vol 624. issue 1-2. 1994-01-13. PMID:8252391. |
diverse physiological actions have been reported for 5-hydroxytryptamine (5-ht, serotonin) in the medial prefrontal cortex (mpfc) and the nucleus accumbens (acb) suggesting that the 5-ht innervation of these forebrain areas may be derived from different populations of neurons. |
1994-01-13 |
2023-08-12 |
rat |
| T Ohmori, T Koyama, A Muraki, I Yamashit. Competitive and noncompetitive N-methyl-D-aspartate antagonists protect dopaminergic and serotonergic neurotoxicity produced by methamphetamine in various brain regions. Journal of neural transmission. General section. vol 92. issue 2-3. 1993-10-12. PMID:7690233. |
four injections of ma (7.5 mg/kg, s.c., at 2 h intervals) caused significant decrements (40-60% of control values) in levels of dopamine (da) and its metabolites in the rat striatum and levels of serotonin (5-ht) and its metabolite in the medial prefrontal cortex, nucleus accumbens, striatum, anterior hypothalamus, amygdala and hippocampus. |
1993-10-12 |
2023-08-12 |
rat |
| M H Baumann, T J Raley, J S Partilla, R B Rothma. Biosynthesis of dopamine and serotonin in the rat brain after repeated cocaine injections: a microdissection mapping study. Synapse (New York, N.Y.). vol 14. issue 1. 1993-07-15. PMID:8511717. |
in chronic saline-treated rats, cocaine dramatically suppressed da and 5-ht synthesis in all forebrain regions examined, including: medial prefrontal cortex, nucleus accumbens, caudate nucleus, olfactory tubercle, and basolateral amygdala. |
1993-07-15 |
2023-08-12 |
rat |
| N E Goeders, J E Smit. Intracranial cocaine self-administration into the medial prefrontal cortex increases dopamine turnover in the nucleus accumbens. The Journal of pharmacology and experimental therapeutics. vol 265. issue 2. 1993-06-22. PMID:8496810. |
discrete response-contingent infusions of cocaine into the medial prefrontal cortex resulted in decreases in the turnover of dopamine and serotonin and increases in norepinephrine utilization at the site of self-injection compared to vehicle-infused controls. |
1993-06-22 |
2023-08-12 |
rat |
| B K Lipska, G E Jaskiw, A Arya, D R Weinberge. Serotonin depletion causes long-term reduction of exploration in the rat. Pharmacology, biochemistry, and behavior. vol 43. issue 4. 1993-02-01. PMID:1475309. |
intraventricular 5,7-dihydroxytryptamine (5,7-dht) induced an almost complete depletion of serotonin [5-hydroxytryptamine (5-ht)] in the medial prefrontal cortex, nucleus accumbens, medial corpus striatum, and hippocampus with no changes in norepinephrine, dopamine or dihydroxyphenylacetic acid concentrations. |
1993-02-01 |
2023-08-11 |
rat |
| M G Feenstra, A Kalsbeek, H van Gale. Neonatal lesions of the ventral tegmental area affect monoaminergic responses to stress in the medial prefrontal cortex and other dopamine projection areas in adulthood. Brain research. vol 596. issue 1-2. 1993-01-28. PMID:1334776. |
a mean decrease of dopamine (da) to 20% and serotonin to 25-30% of control levels was found in the medial prefrontal cortex (mpfc) and amygdala/piriform cortex (a/pc) of adult rats with neonatal lesions of the ventral tegmental area (vta). |
1993-01-28 |
2023-08-11 |
rat |
| R Y Yukhananov, T M Tennilä, T I Miroshnicenko, V S Kudrin, A N Ushakov, E I Melnik, I I Michaleva, K S Rayevsky, M M Airaksinen, A I Maisk. Ethanol and delta-sleep-inducing peptide: effects on brain monoamines. Pharmacology, biochemistry, and behavior. vol 43. issue 3. 1992-12-30. PMID:1448465. |
delta-sleep-inducing peptide (dsip) injection reduced the level of 5-ht in the medial prefrontal cortex (mfc) in both groups, did not affect the concentration of da or dopac, but increased hva in the striatum of ha rats. |
1992-12-30 |
2023-08-11 |
rat |
| C R Ashby, E Edwards, R Y Wan. Action of serotonin in the medial prefrontal cortex: mediation by serotonin3-like receptors. Synapse (New York, N.Y.). vol 10. issue 1. 1992-03-24. PMID:1536032. |
action of serotonin in the medial prefrontal cortex: mediation by serotonin3-like receptors. |
1992-03-24 |
2023-08-11 |
Not clear |
| R Araneda, R Andrad. 5-Hydroxytryptamine2 and 5-hydroxytryptamine 1A receptors mediate opposing responses on membrane excitability in rat association cortex. Neuroscience. vol 40. issue 2. 1991-06-12. PMID:1851255. |
the effects of serotonin on pyramidal cells of layer v of the medial prefrontal cortex were examined using intracellular recording techniques in rat brain slices in vitro. |
1991-06-12 |
2023-08-11 |
rat |
| J Mantz, R Godbout, J P Tassin, J Glowinski, A M Thierr. Inhibition of spontaneous and evoked unit activity in the rat medial prefrontal cortex by mesencephalic raphe nuclei. Brain research. vol 524. issue 1. 1990-10-26. PMID:2119244. |
the rat medial prefrontal cortex (pfc) receives a serotoninergic (5-ht) innervation which originates from the mesencephalic raphe nuclei. |
1990-10-26 |
2023-08-11 |
rat |
| M P Gallowa. Regulation of dopamine and serotonin synthesis by acute administration of cocaine. Synapse (New York, N.Y.). vol 6. issue 1. 1990-10-18. PMID:2119072. |
inhibition of da and 5ht synthesis ranged from 35% to 60% depending on the brain region and was apparent in dopaminergic fields such as the medial prefrontal cortex, nucleus accumbens, piriform cortex, striatum, and in noradrenergic fields, such as the hippocampus and temporal cortex. |
1990-10-18 |
2023-08-11 |
Not clear |