| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Thibaut Sesia, Vincent Bulthuis, Sonny Tan, Lee Wei Lim, Rinske Vlamings, Arjan Blokland, Harry W M Steinbusch, Trevor Sharp, Veerle Visser-Vandewalle, Yasin Teme. Deep brain stimulation of the nucleus accumbens shell increases impulsive behavior and tissue levels of dopamine and serotonin. Experimental neurology. vol 225. issue 2. 2010-10-01. PMID:20615406. |
in addition, in a second experiment, the effect of dbs of the nac core and shell on extracellular dopamine and serotonin levels was assessed in the nac and medial prefrontal cortex. |
2010-10-01 |
2023-08-12 |
human |
| Thibaut Sesia, Vincent Bulthuis, Sonny Tan, Lee Wei Lim, Rinske Vlamings, Arjan Blokland, Harry W M Steinbusch, Trevor Sharp, Veerle Visser-Vandewalle, Yasin Teme. Deep brain stimulation of the nucleus accumbens shell increases impulsive behavior and tissue levels of dopamine and serotonin. Experimental neurology. vol 225. issue 2. 2010-10-01. PMID:20615406. |
these effects were associated with increased levels of dopamine and serotonin in the nac, but not in the medial prefrontal cortex. |
2010-10-01 |
2023-08-12 |
human |
| Aki Takahashi, Akiko Shimamoto, Christopher O Boyson, Joseph F DeBold, Klaus A Micze. GABA(B) receptor modulation of serotonin neurons in the dorsal raphé nucleus and escalation of aggression in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 35. 2010-09-20. PMID:20810897. |
in vivo microdialysis showed that gaba(b) activation in the drn increased extracellular 5-ht level in the medial prefrontal cortex. |
2010-09-20 |
2023-08-12 |
mouse |
| Yuji Kitaichi, Takeshi Inoue, Shin Nakagawa, Shuken Boku, Takeshi Izumi, Tsukasa Koyam. Combined treatment with MAO-A inhibitor and MAO-B inhibitor increases extracellular noradrenaline levels more than MAO-A inhibitor alone through increases in beta-phenylethylamine. European journal of pharmacology. vol 637. issue 1-3. 2010-09-07. PMID:20406628. |
using in vivo microdialysis methods, we measured extracellular noradrenaline and serotonin levels following administration of ro 41-1049, a reversible mao-a inhibitor and/or lazabemide, a reversible mao-b inhibitor in the medial prefrontal cortex (mpfc) of rats. |
2010-09-07 |
2023-08-12 |
rat |
| Xavier López-Gil, Francesc Artigas, Albert Adel. Unraveling monoamine receptors involved in the action of typical and atypical antipsychotics on glutamatergic and serotonergic transmission in prefrontal cortex. Current pharmaceutical design. vol 16. issue 5. 2010-06-25. PMID:19909228. |
in the present work, we used in vivo microdialysis to examine: first, the effects of mk-801, on the efflux of glutamate and serotonin (5-ht) in the medial prefrontal cortex (mpfc) of the rat; second, whether the mk-801-induced changes in the cortical efflux of both transmitters could be blocked by atypical (clozapine and olanzapine) and classical (haloperidol and chlorpromazine) antipsychotic drugs given intra-mpfc; and third, the role of local blockade of dopamine d(2)/d(3)/d(4), serotonin 5-ht(2a) and alpha(1)-adrenergic receptors as well as agonism at dopamine d(1)/d(5) and 5-ht(1a) receptors in the mpfc on the increased efflux of glutamate and 5-ht elicited by mk-801. |
2010-06-25 |
2023-08-12 |
rat |
| Zhimin Li, Mona Boules, Katrina Williams, Joanna Peris, Elliott Richelso. The novel neurotensin analog NT69L blocks phencyclidine (PCP)-induced increases in locomotor activity and PCP-induced increases in monoamine and amino acids levels in the medial prefrontal cortex. Brain research. vol 1311. 2010-04-08. PMID:19948149. |
pcp injection significantly increased activity as well as the extracellular concentration of norepinephrine (ne), 5-ht, dopamine (da), and glutamate in the medial prefrontal cortex (mpfc). |
2010-04-08 |
2023-08-12 |
rat |
| Qiao Jun Zhang, Shuang Wang, Jian Liu, Umar Ali, Zhen Hua Gui, Zhong Heng Wu, Yan Ping Hui, Yong Wang, Li Che. Unilateral lesion of the nigrostriatal pathway decreases the response of interneurons in medial prefrontal cortex to 5-HT 2A/2C receptor stimulation in the rat. Brain research. vol 1312. 2010-03-25. PMID:19948151. |
unilateral lesion of the nigrostriatal pathway decreases the response of interneurons in medial prefrontal cortex to 5-ht 2a/2c receptor stimulation in the rat. |
2010-03-25 |
2023-08-12 |
rat |
| Qiao Jun Zhang, Shuang Wang, Jian Liu, Umar Ali, Zhen Hua Gui, Zhong Heng Wu, Yan Ping Hui, Yong Wang, Li Che. Unilateral lesion of the nigrostriatal pathway decreases the response of interneurons in medial prefrontal cortex to 5-HT 2A/2C receptor stimulation in the rat. Brain research. vol 1312. 2010-03-25. PMID:19948151. |
the aim of the present study was to investigate changes in the firing rate and pattern of interneurons in the medial prefrontal cortex (mpfc), and effects of 5-ht(2a/2c) receptor agonist doi and antagonist ritanserin, and the selective 5-ht(2c) receptor antagonist sb 242084 on the neuronal firing in rats with 6-hydroxydopamine (6-ohda) lesions of the substantia nigra pars compacta (snc) by extracellular recording in vivo. |
2010-03-25 |
2023-08-12 |
rat |
| Vasileios Boulougouris, Trevor W Robbin. Enhancement of spatial reversal learning by 5-HT2C receptor antagonism is neuroanatomically specific. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 3. 2010-02-05. PMID:20089901. |
the roles of 5-ht(2c) and 5-ht(2a) receptors were examined within some of the brain regions implicated in cognitive flexibility, namely the orbitofrontal cortex (ofc), medial prefrontal cortex (mpfc), and nucleus accumbens (nac), by means of targeted infusions of selective 5-ht(2c) and 5-ht(2a) receptor antagonists (sb 242084 and m100907, respectively). |
2010-02-05 |
2023-08-12 |
Not clear |
| Julie A Brennan, Radka Graf, Steven M Grauer, Rachel L Navarra, Claudine M Pulicicchio, Zoë A Hughes, Qian Lin, Caitlin Wantuch, Sharon Rosenzweig-Lipson, Farhana Pruthi, Margaret Lai, Deborah Smith, Wouter Goutier, Martina van de Neut, Albert J Robichaud, David Rotella, Rolf W Feenstra, Chris Kruse, Pierre Broqua, Chad E Beyer, Andrew C McCreary, Mark H Pausch, Karen L Marqui. WS-50030 [7-{4-[3-(1H-inden-3-yl)propyl]piperazin-1-yl}-1,3-benzoxazol-2(3H)-one]: a novel dopamine D2 receptor partial agonist/serotonin reuptake inhibitor with preclinical antipsychotic-like and antidepressant-like activity. The Journal of pharmacology and experimental therapeutics. vol 332. issue 1. 2010-01-26. PMID:19828876. |
consistent with this in vitro profile, ws-50030 (10 mg/kg/day, 21 days) significantly increased extracellular 5-ht in the rat medial prefrontal cortex, short-term ws-50030 treatment blocked apomorphine-induced climbing (id(50), 0.51 mg/kg) in a dose range that produced minimal catalepsy in mice and induced low levels of contralateral rotation in rats with unilateral substantia nigra 6-hydroxydopamine lesions (10 mg/kg i.p. |
2010-01-26 |
2023-08-12 |
mouse |
| Joanna Dabrowska, Przemyslaw Nowak, Ryszard Bru. Reactivity of 5-HT1A receptor in adult rats after neonatal noradrenergic neurons' lesion--implications for antidepressant-like action. Brain research. vol 1239. 2010-01-12. PMID:18789911. |
during a microdialysis study of anaesthetized rats, the 5-ht1a receptor agonist, r-(+)-8-oh-dpat (0.1 mg/kg), decreased 5-ht release in the medial prefrontal cortex of control rats but this effect was significantly attenuated in dsp-4-treated animals (10-12 weeks old). |
2010-01-12 |
2023-08-12 |
rat |
| J B Savitz, W C Drevet. Imaging phenotypes of major depressive disorder: genetic correlates. Neuroscience. vol 164. issue 1. 2010-01-11. PMID:19358877. |
concerning neuroreceptor pet imaging, decreased 5-ht(1a) binding potential in the raphe, medial temporal lobe, and medial prefrontal cortex (mpfc) has been strongly associated with mdd, and may be impacted by a functional single nucleotide polymorphism in the promoter region of the 5-ht(1a) gene (htr1a: -1019 c/g; rs6295). |
2010-01-11 |
2023-08-12 |
Not clear |
| Tultul Nayyar, Michael Bubser, Marcus C Ferguson, M Diana Neely, J Shawn Goodwin, Thomas J Montine, Ariel Y Deutch, Twum A Ansa. Cortical serotonin and norepinephrine denervation in parkinsonism: preferential loss of the beaded serotonin innervation. The European journal of neuroscience. vol 30. issue 2. 2010-01-08. PMID:19659923. |
in contrast, we observed an enduring decrease in 5-ht and ne concentrations in both the somatosensory cortex and medial prefrontal cortex (pfc). |
2010-01-08 |
2023-08-12 |
mouse |
| Patrick M Fisher, Carolyn C Meltzer, Julie C Price, Rhaven L Coleman, Scott K Ziolko, Carl Becker, Eydie L Moses-Kolko, Sarah L Berga, Ahmad R Harir. Medial prefrontal cortex 5-HT(2A) density is correlated with amygdala reactivity, response habituation, and functional coupling. Cerebral cortex (New York, N.Y. : 1991). vol 19. issue 11. 2010-01-04. PMID:19321655. |
medial prefrontal cortex 5-ht(2a) density is correlated with amygdala reactivity, response habituation, and functional coupling. |
2010-01-04 |
2023-08-12 |
human |
| Benoit Labonte, Francis Rodriguez Bambico, Gabriella Gobb. Potentiation of excitatory serotonergic responses by MK-801 in the medial prefrontal cortex. Naunyn-Schmiedeberg's archives of pharmacology. vol 380. issue 5. 2009-12-29. PMID:19727675. |
the goal of this study was to characterise the response of pyramidal neurons in the medial prefrontal cortex (mpfc) to 5-ht and nmda before and after administration of the nmda receptor antagonist, mk-801 (dizocilpine), a well-validated pharmacological model of psychosis. |
2009-12-29 |
2023-08-12 |
rat |
| M Kuramochi, S Nakamur. Effects of postnatal isolation rearing and antidepressant treatment on the density of serotonergic and noradrenergic axons and depressive behavior in rats. Neuroscience. vol 163. issue 1. 2009-12-15. PMID:19524023. |
in the prelimbic area and infralimbic area of medial prefrontal cortex and the dentate gyrus of the hippocampus, the density of 5-ht axons was not affected by social iso alone, but was reduced when animals were socially isolated after neonatal cl treatment. |
2009-12-15 |
2023-08-12 |
rat |
| S Wang, Q J Zhang, J Liu, Z H Wu, U Ali, Y Wang, L Chen, Z H Gu. The firing activity of pyramidal neurons in medial prefrontal cortex and their response to 5-hydroxytryptamine-1A receptor stimulation in a rat model of Parkinson's disease. Neuroscience. vol 162. issue 4. 2009-11-10. PMID:19410634. |
the changes in the firing rate and firing pattern of pyramidal neurons in medial prefrontal cortex (mpfc) and the effects of selective 5-hydroxytryptamine-(1a) (5-ht(1a)) receptor agonist (r)-(+)-8-hydroxy-2-(dipropylamino)tetralin hydrobromide (8-oh-dpat) and antagonist n-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-n-2-pyridylcyclohexane carboxamide maleate salt (way-100635) on the firing activity of the neurons were studied in sham-lesioned rats and rats with 6-hydroxydopamine lesions of the substantia nigra pars compacta (snc). |
2009-11-10 |
2023-08-12 |
rat |
| Hirokazu Matsuzaki, Takeshi Izumi, Machiko Matsumoto, Hiroko Togashi, Taku Yamaguchi, Takayuki Yoshida, Masahiko Watanabe, Mitsuhiro Yoshiok. Early postnatal stress affects 5-HT1A receptor function in the medial prefrontal cortex in adult rats. European journal of pharmacology. vol 615. issue 1-3. 2009-11-10. PMID:19470384. |
the goal of the present study was to investigate whether early postnatal stress influences 5-ht(1a) receptor function in the medial prefrontal cortex in adult rats. |
2009-11-10 |
2023-08-12 |
rat |
| Hirokazu Matsuzaki, Takeshi Izumi, Machiko Matsumoto, Hiroko Togashi, Taku Yamaguchi, Takayuki Yoshida, Masahiko Watanabe, Mitsuhiro Yoshiok. Early postnatal stress affects 5-HT1A receptor function in the medial prefrontal cortex in adult rats. European journal of pharmacology. vol 615. issue 1-3. 2009-11-10. PMID:19470384. |
we found that local perfusion of 8-oh-dpat via a dialysis probe decreased extracellular 5-ht levels in the medial prefrontal cortex of the non-fs group, but not in the 3wfs group. |
2009-11-10 |
2023-08-12 |
rat |
| Hirokazu Matsuzaki, Takeshi Izumi, Machiko Matsumoto, Hiroko Togashi, Taku Yamaguchi, Takayuki Yoshida, Masahiko Watanabe, Mitsuhiro Yoshiok. Early postnatal stress affects 5-HT1A receptor function in the medial prefrontal cortex in adult rats. European journal of pharmacology. vol 615. issue 1-3. 2009-11-10. PMID:19470384. |
therefore, aversive stress in the third week of the postnatal period attenuates 5-ht(1a) receptor function in the medial prefrontal cortex in adulthood and produces feedback inhibition of the raphe nuclei via postsynaptic 5-ht(1a) receptors. |
2009-11-10 |
2023-08-12 |
rat |