| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fritz Kobe, Daria Guseva, Thomas P Jensen, Alexander Wirth, Ute Renner, Dietmar Hess, Michael Müller, Lucian Medrihan, Weiqi Zhang, Mingyue Zhang, Katharina Braun, Sören Westerholz, Andreas Herzog, Konstantin Radyushkin, Ahmed El-Kordi, Hannelore Ehrenreich, Diethelm W Richter, Dmitri A Rusakov, Evgeni Ponimaski. 5-HT7R/G12 signaling regulates neuronal morphology and function in an age-dependent manner. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 9. 2012-04-20. PMID:22378867. |
expression analysis reveals that the production of 5-ht(7) and gα(12)-proteins in the hippocampus undergoes strong regulation with a pronounced transient increase during early postnatal stages. |
2012-04-20 |
2023-08-12 |
mouse |
| C D Conrad, M L Mauldin-Jourdain, R J Hobb. Metyrapone reveals that previous chronic stress differentially impairs hippocampal-dependent memory. Stress (Amsterdam, Netherlands). vol 4. issue 4. 2012-04-16. PMID:18301732. |
chronic stress facilitates fear conditioning in rats with hippocampal neuronal atrophy and in rats in which the atrophy is prevented with tianeptine, a serotonin re-uptake enhancer. |
2012-04-16 |
2023-08-12 |
rat |
| Marisa Soledad Ghersi, Sebastian M Casas, Carla Escudero, Valeria P Carlini, Florencia Buteler, Ricardo J Cabrera, Helgi B Schiöth, Susana R de Bariogli. Ghrelin inhibited serotonin release from hippocampal slices. Peptides. vol 32. issue 11. 2012-04-16. PMID:21820473. |
ghrelin inhibited serotonin release from hippocampal slices. |
2012-04-16 |
2023-08-12 |
rat |
| Marisa Soledad Ghersi, Sebastian M Casas, Carla Escudero, Valeria P Carlini, Florencia Buteler, Ricardo J Cabrera, Helgi B Schiöth, Susana R de Bariogli. Ghrelin inhibited serotonin release from hippocampal slices. Peptides. vol 32. issue 11. 2012-04-16. PMID:21820473. |
in our laboratory we have shown that (a) ghr administration, either intracerebroventricular or directly into the hippocampus enhanced memory consolidation in a step down test in rats (b) the effect of ghr upon memory decreases in animals pretreated with a serotonin (5-ht) reuptake inhibitor, fluoxetine, suggesting that ghr effects in the hippocampus could be related to the availability of 5-ht. |
2012-04-16 |
2023-08-12 |
rat |
| Marisa Soledad Ghersi, Sebastian M Casas, Carla Escudero, Valeria P Carlini, Florencia Buteler, Ricardo J Cabrera, Helgi B Schiöth, Susana R de Bariogli. Ghrelin inhibited serotonin release from hippocampal slices. Peptides. vol 32. issue 11. 2012-04-16. PMID:21820473. |
taking in mint these evidences, we studied the release of radioactive 5-ht to the superfusion medium from hippocampal slices treated with two doses of ghr (0.3 and 3 nm/μl). |
2012-04-16 |
2023-08-12 |
rat |
| Marisa Soledad Ghersi, Sebastian M Casas, Carla Escudero, Valeria P Carlini, Florencia Buteler, Ricardo J Cabrera, Helgi B Schiöth, Susana R de Bariogli. Ghrelin inhibited serotonin release from hippocampal slices. Peptides. vol 32. issue 11. 2012-04-16. PMID:21820473. |
in another set of experiments, ghr was infused into the ca1 area of hippocampus of the rats immediately after training in the step down test and the 5-ht release from slices was studied 24h after ghr injection showing that in this condition also the 5-ht release was inhibited (h = 11.72, df = 1, p ≤ 0.05). |
2012-04-16 |
2023-08-12 |
rat |
| Seung-Soo Baek, Tae-Won Jun, Ki-Jeong Kim, Mal-Soon Shin, Sun-Young Kang, Chang-Ju Ki. Effects of postnatal treadmill exercise on apoptotic neuronal cell death and cell proliferation of maternal-separated rat pups. Brain & development. vol 34. issue 1. 2012-03-30. PMID:21353411. |
in this study, we investigated the effects of postnatal treadmill exercise on the long-term memory capability, spatial learning ability, and depressive state, on the 5-hydroxytryptamine (5-ht, serotonin) synthesis and tryptophan hydroxylase (tph) expression in the dorsal raphe nuclei, and on the apoptosis and cell proliferation in the hippocampal dentate gyrus of rat pups following maternal separation. |
2012-03-30 |
2023-08-12 |
rat |
| Seung-Soo Baek, Tae-Won Jun, Ki-Jeong Kim, Mal-Soon Shin, Sun-Young Kang, Chang-Ju Ki. Effects of postnatal treadmill exercise on apoptotic neuronal cell death and cell proliferation of maternal-separated rat pups. Brain & development. vol 34. issue 1. 2012-03-30. PMID:21353411. |
the 5-ht synthesis and tph expression in the dorsal raphe nuclei and cell proliferation in the hippocampal dentate gyrus were significantly decreased in the maternal-separated rat pups, and postnatal treadmill exercise increased 5-ht synthesis, the tph expression, and the cell proliferation. |
2012-03-30 |
2023-08-12 |
rat |
| Dasiel O Borroto-Escuela, Wilber Romero-Fernandez, Giuseppa Mudó, Mileidys Pérez-Alea, Francisco Ciruela, Alexander O Tarakanov, Manuel Narvaez, Valentina Di Liberto, Luigi F Agnati, Natale Belluardo, Kjell Fux. Fibroblast growth factor receptor 1- 5-hydroxytryptamine 1A heteroreceptor complexes and their enhancement of hippocampal plasticity. Biological psychiatry. vol 71. issue 1. 2012-03-30. PMID:22035699. |
fibroblast growth factor receptor 1- 5-hydroxytryptamine 1a heteroreceptor complexes and their enhancement of hippocampal plasticity. |
2012-03-30 |
2023-08-12 |
Not clear |
| Dasiel O Borroto-Escuela, Wilber Romero-Fernandez, Giuseppa Mudó, Mileidys Pérez-Alea, Francisco Ciruela, Alexander O Tarakanov, Manuel Narvaez, Valentina Di Liberto, Luigi F Agnati, Natale Belluardo, Kjell Fux. Fibroblast growth factor receptor 1- 5-hydroxytryptamine 1A heteroreceptor complexes and their enhancement of hippocampal plasticity. Biological psychiatry. vol 71. issue 1. 2012-03-30. PMID:22035699. |
the hippocampus and its 5-hydroxytryptamine transmission plays an important role in depression related to its involvement in limbic circuit plasticity. |
2012-03-30 |
2023-08-12 |
Not clear |
| J H Meye. Neuroimaging markers of cellular function in major depressive disorder: implications for therapeutics, personalized medicine, and prevention. Clinical pharmacology and therapeutics. vol 91. issue 2. 2012-03-20. PMID:22218074. |
neuroimaging of monoamine oxidase-a (mao-a) binding; glutamate levels; indexes of 5-ht(2a), 5-htt, 5-ht(1a), and 5-ht(1b) receptors; levels of dopamine transporters d(1) and d(2); and hippocampal volume are described here. |
2012-03-20 |
2023-08-12 |
Not clear |
| Yunxiang Su, Ling Xu. [Effects of jingqianshu granule on expression of 5-HT(1A)R of PMS model rats with liver-qi stagnation]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 36. issue 24. 2012-03-20. PMID:22368865. |
to research the effect of the jingqianshu granule (jqs) on the expression of serotonin receptor-1a (5-ht(1a)r) in hippocampus and hypothalamus of premenstrual syndrome (pms) model rats with liver-qi depression. |
2012-03-20 |
2023-08-12 |
rat |
| Sung Min Nam, Dae Young Yoo, Woosuk Kim, Miyoung Yoo, Dong-Woo Kim, Moo-Ho Won, In Koo Hwang, Yeo Sung Yoo. Effects of s-allyl-L-cysteine on cell proliferation and neuroblast differentiation in the mouse dentate gyrus. The Journal of veterinary medical science. vol 73. issue 8. 2012-03-13. PMID:21467757. |
furthermore, serotonin 1a receptor (5-ht(1a)) levels in the hippocampus were also increased. |
2012-03-13 |
2023-08-12 |
mouse |
| Kristen A Horner, Yamiece E Gilbert, Erika S Nobl. Differential regulation of 5-HT2A receptor mRNA expression following withdrawal from a chronic escalating dose regimen of D-amphetamine. Brain research. vol 1390. 2012-03-07. PMID:21420940. |
the goal of the current study was to determine the effects of chronic, escalating doses of d-amphetamine (d-amph) and withdrawal on the expression of 5-ht(2a) receptors in the cortex, caudate putamen, nac and hippocampus of rat brain. |
2012-03-07 |
2023-08-12 |
rat |
| Kristen A Horner, Yamiece E Gilbert, Erika S Nobl. Differential regulation of 5-HT2A receptor mRNA expression following withdrawal from a chronic escalating dose regimen of D-amphetamine. Brain research. vol 1390. 2012-03-07. PMID:21420940. |
chronic, escalating doses of d-amph, followed by a 24 h withdrawal period, significantly decreased 5-ht(2a) receptor mrna expression in the prefrontal, motor and cingulate cortices, while 5-ht(2a) receptor mrna expression in the nac, caudal cpu and hippocampus were significantly increased. |
2012-03-07 |
2023-08-12 |
rat |
| Hiwote Belay, Christie L Burton, Vedran Lovic, Michael J Meaney, Marla Sokolowski, Alison S Flemin. Early adversity and serotonin transporter genotype interact with hippocampal glucocorticoid receptor mRNA expression, corticosterone, and behavior in adult male rats. Behavioral neuroscience. vol 125. issue 2. 2012-03-06. PMID:21463019. |
early adversity and serotonin transporter genotype interact with hippocampal glucocorticoid receptor mrna expression, corticosterone, and behavior in adult male rats. |
2012-03-06 |
2023-08-12 |
rat |
| V Arora, A Kuhad, V Tiwari, K Chopr. Curcumin ameliorates reserpine-induced pain-depression dyad: behavioural, biochemical, neurochemical and molecular evidences. Psychoneuroendocrinology. vol 36. issue 10. 2012-03-05. PMID:21612876. |
this behavioural deficit was integrated with decrease in the biogenic amine (dopamine, norepinephrine and serotonin) levels along with increased substance p concentration, nitrodative stress, inflammatory cytokines, nf-κβ and caspase-3 levels in different brain regions (cortex and hippocampus) of the reserpinised rats. |
2012-03-05 |
2023-08-12 |
rat |
| Isabel Marco, Margarita Valhondo, Mar Martín-Fontecha, Henar Vázquez-Villa, Joaquín Del Río, Anna Planas, Onintza Sagredo, José A Ramos, Iván R Torrecillas, Leonardo Pardo, Diana Frechilla, Bellinda Benhamú, María L López-Rodrígue. New serotonin 5-HT(1A) receptor agonists with neuroprotective effect against ischemic cell damage. Journal of medicinal chemistry. vol 54. issue 23. 2012-03-05. PMID:22029386. |
interestingly, compound 26 (2-{6-[(3,4-dihydro-2h-chromen-2-ylmethyl)amino]hexyl}tetrahydro-1h-pyrrolo[1,2-c]imidazole-1,3(2h)-dione) has been characterized as a high-affinity and potent 5-ht(1a)r agonist (k(i) = 5.9 nm, ec(50) = 21.8 nm) and exhibits neuroprotective effect in neurotoxicity assays in primary cell cultures from rat hippocampus and in the mcao model of focal cerebral ischemia in rats. |
2012-03-05 |
2023-08-12 |
rat |
| Ahmad A Khundakar, Tyra S C Zetterströ. Effects of GABAB ligands alone and in combination with paroxetine on hippocampal BDNF gene expression. European journal of pharmacology. vol 671. issue 1-3. 2012-03-01. PMID:21930121. |
the inhibitory action by the selective serotonin re-uptake inhibitor (ssri) paroxetine on hippocampal bdnf mrna was also attenuated by cgp 46381. |
2012-03-01 |
2023-08-12 |
rat |
| T Christensen, C F Bisgaard, O Wibor. Biomarkers of anhedonic-like behavior, antidepressant drug refraction, and stress resilience in a rat model of depression. Neuroscience. vol 196. 2012-02-23. PMID:21889970. |
depression-related transcriptomic changes in gene expression profiles were investigated in laser-captured microdissected (lcm) rat hippocampal granular cell layers (gcl) using the chronic mild stress (cms) rat model of depression and chronic administration of two selective serotonin reuptake inhibitors (ssris), escitalopram and sertraline. |
2012-02-23 |
2023-08-12 |
rat |