| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Harriët Schellekens, Gerard Clarke, Ian B Jeffery, Timothy G Dinan, John F Crya. Dynamic 5-HT2C receptor editing in a mouse model of obesity. PloS one. vol 7. issue 3. 2012-08-20. PMID:22448217. |
this suggests that a dynamic regulation exists of the appetite-suppressing effects of the 5-ht(2c) receptor in both the hypothalamus and the hippocampus in the ob/ob mice model of obesity. |
2012-08-20 |
2023-08-12 |
mouse |
| Milene C Carvalho, Caio M Moreira, Janaína M Zanoveli, Marcus L Brandã. Central, but not basolateral, amygdala involvement in the anxiolytic-like effects of midazolam in rats in the elevated plus maze. Journal of psychopharmacology (Oxford, England). vol 26. issue 4. 2012-08-17. PMID:21148026. |
in the present study, we ethopharmacologically analyzed the behavior of rats subjected to the epm and the tissue content of the monoamines dopamine (da) and serotonin (5-ht) and their metabolites in the nucleus accumbens (nac), dorsal hippocampus (dh), and dorsal striatum (ds) of animals injected with saline or midazolam (20 and 30 nmol/0.2 µl) into the bla or cea. |
2012-08-17 |
2023-08-12 |
rat |
| Sepehr Hafizi, Florence Serres, Qi Pei, Susan Totterdell, Trevor Shar. Evidence for the differential co-localization of neurokinin-1 receptors with 5-HT receptor subtypes in rat forebrain. Journal of psychopharmacology (Oxford, England). vol 26. issue 4. 2012-08-17. PMID:22057017. |
co-localization was highest in the medial septum (88% nk(1)r expressing cells were 5-ht(1a) receptor-positive) and hippocampal regions (e.g. |
2012-08-17 |
2023-08-12 |
rat |
| Sepehr Hafizi, Florence Serres, Qi Pei, Susan Totterdell, Trevor Shar. Evidence for the differential co-localization of neurokinin-1 receptors with 5-HT receptor subtypes in rat forebrain. Journal of psychopharmacology (Oxford, England). vol 26. issue 4. 2012-08-17. PMID:22057017. |
in contrast, co-localization between nk(1)rs and 5-ht(2a) receptors was infrequent (< 8%) in most areas examined except for the hippocampus (e.g. |
2012-08-17 |
2023-08-12 |
rat |
| Marco Bortolato, Kevin Chen, Sean C Godar, Gao Chen, Weihua Wu, Igor Rebrin, Mollee R Farrell, Anna L Scott, Cara L Wellman, Jean C Shi. Social deficits and perseverative behaviors, but not overt aggression, in MAO-A hypomorphic mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 13. 2012-08-14. PMID:21832987. |
in the prefrontal cortex and amygdala, mao-a(neo) mice showed low, yet detectable, mao-a catalytic activity, as well as 5-ht levels equivalent to wt littermates; conversely, the hippocampus and midbrain of mao-a(neo) mice featured a neurochemical profile akin to mao-a-knockout (ko) mice, with undetectable mao-a activity and high 5-ht concentrations. |
2012-08-14 |
2023-08-12 |
mouse |
| Katsunori Kobayashi, Eisuke Haneda, Makoto Higuchi, Tetsuya Suhara, Hidenori Suzuk. Chronic fluoxetine selectively upregulates dopamine D₁-like receptors in the hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 6. 2012-08-14. PMID:22278095. |
the dentate gyrus of the hippocampus has been implicated in mechanisms of action of selective serotonin reuptake inhibitors (ssris). |
2012-08-14 |
2023-08-12 |
mouse |
| Aparecida Vines, Ana Marcia Delattre, Marcelo M S Lima, Laís Soares Rodrigues, Deborah Suchecki, Ricardo B Machado, Sergio Tufik, Sofia I R Pereira, Sílvio M Zanata, Anete Curte Ferra. The role of 5-HT₁A receptors in fish oil-mediated increased BDNF expression in the rat hippocampus and cortex: a possible antidepressant mechanism. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21740919. |
the present study was performed to evaluate the involvement of serotonin (5-ht) receptors, particularly of 5-ht(1a), and hippocampal brain-derived neurotrophic factor (bdnf) expression in the antidepressant effect of ω-3 pufa supplementation. |
2012-08-13 |
2023-08-12 |
rat |
| Aparecida Vines, Ana Marcia Delattre, Marcelo M S Lima, Laís Soares Rodrigues, Deborah Suchecki, Ricardo B Machado, Sergio Tufik, Sofia I R Pereira, Sílvio M Zanata, Anete Curte Ferra. The role of 5-HT₁A receptors in fish oil-mediated increased BDNF expression in the rat hippocampus and cortex: a possible antidepressant mechanism. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21740919. |
in experiment 2, cortical and hippocampal contents of bdnf, 5-ht, dopamine (da) and its metabolites, 5-hydroxyindoleacetic acid (5-hiaa), and 3,4-dihydroxyphenylacetic acid (dopac), were determined in animals subjected to the same protocol. |
2012-08-13 |
2023-08-12 |
rat |
| Aparecida Vines, Ana Marcia Delattre, Marcelo M S Lima, Laís Soares Rodrigues, Deborah Suchecki, Ricardo B Machado, Sergio Tufik, Sofia I R Pereira, Sílvio M Zanata, Anete Curte Ferra. The role of 5-HT₁A receptors in fish oil-mediated increased BDNF expression in the rat hippocampus and cortex: a possible antidepressant mechanism. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21740919. |
in 90 day-old rats, 5-ht content in the hippocampus was increased, whereas 5-hiaa formation was diminished in the fish oil group. |
2012-08-13 |
2023-08-12 |
rat |
| Aparecida Vines, Ana Marcia Delattre, Marcelo M S Lima, Laís Soares Rodrigues, Deborah Suchecki, Ricardo B Machado, Sergio Tufik, Sofia I R Pereira, Sílvio M Zanata, Anete Curte Ferra. The role of 5-HT₁A receptors in fish oil-mediated increased BDNF expression in the rat hippocampus and cortex: a possible antidepressant mechanism. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21740919. |
we suggest the occurrence of a reciprocal involvement of 5-ht(1a) receptors activation and the hippocampal bdnf-increased expression mediated by fish oil supplementation. |
2012-08-13 |
2023-08-12 |
rat |
| Galina T Shishkina, Tatyana S Kalinina, Inna V Berezova, Nikolay N Dygal. Stress-induced activation of the brainstem Bcl-xL gene expression in rats treated with fluoxetine: correlations with serotonin metabolism and depressive-like behavior. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21740920. |
mechanisms underlying stress-induced depression and antidepressant drug action were shown to involve alterations in serotonergic (5-ht) neurotransmission and expression of genes coding for proteins associated with neurotrophic signaling pathways and cell-survival in the hippocampus and cortex. |
2012-08-13 |
2023-08-12 |
rat |
| David Petrik, Diane C Lagace, Amelia J Eisc. The neurogenesis hypothesis of affective and anxiety disorders: are we mistaking the scaffolding for the building? Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21945290. |
the hypothesis was established in the 1990s but was built on a broad foundation of earlier research on the hippocampus, serotonin and mdd. |
2012-08-13 |
2023-08-12 |
mouse |
| Julie Espallergues, Takayoshi Mamiya, Monique Vallée, Takenao Koseki, Toshitaka Nabeshima, Jamal Temsamani, Claude Laruelle, Tangui Mauric. The antidepressant-like effects of the 3β-hydroxysteroid dehydrogenase inhibitor trilostane in mice is related to changes in neuroactive steroid and monoamine levels. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21945799. |
trilostane (25 mg/kg) treatment significantly increased 5-ht and (-)-norepinephrine (ne) turnovers in the hippocampus, an effect likely related to its antidepressant action. |
2012-08-13 |
2023-08-12 |
mouse |
| Malgorzata Elzbieta Zajda, Pawel Krzascik, Martin Hill, Maria Dorota Majewsk. Psychomotor and rewarding properties of the neurosteroids dehydroepiandrosterone sulphate and androsterone: effects on monoamine and steroid metabolism. Acta neurobiologiae experimentalis. vol 72. issue 1. 2012-08-09. PMID:22508085. |
dheas reduced the hippocampal dopamine level, increased striatal homovanilic acid (hva) and decreased the striatal serotonin concentrations. |
2012-08-09 |
2023-08-12 |
rat |
| Malgorzata Elzbieta Zajda, Pawel Krzascik, Martin Hill, Maria Dorota Majewsk. Psychomotor and rewarding properties of the neurosteroids dehydroepiandrosterone sulphate and androsterone: effects on monoamine and steroid metabolism. Acta neurobiologiae experimentalis. vol 72. issue 1. 2012-08-09. PMID:22508085. |
androsterone did not affect dopamine levels or turnover, but increased noradrenaline concentration and serotonin turnover in the hippocampus. |
2012-08-09 |
2023-08-12 |
rat |
| Erica Y Shen, Syed F Ali, Jerrold S Meye. Chronic administration of THC prevents the behavioral effects of intermittent adolescent MDMA administration and attenuates MDMA-induced hyperthermia and neurotoxicity in rats. Neuropharmacology. vol 61. issue 8. 2012-08-01. PMID:21763331. |
thc additionally attenuated mdma -induced decreases in 5-ht levels and in sert binding in the frontal cortex, parietal cortex, and striatum, but not in the hippocampus. |
2012-08-01 |
2023-08-12 |
rat |
| Carmela M Reichel, Lauren A Ramsey, Marek Schwendt, Jacqueline F McGinty, Ronald E Se. Methamphetamine-induced changes in the object recognition memory circuit. Neuropharmacology. vol 62. issue 2. 2012-07-27. PMID:22115899. |
subsequently, transporters for serotonin (sert) and norepinephrine (net) were quantified using western blot in tissue obtained from the hippocampus, perirhinal cortex, and prefrontal cortex. |
2012-07-27 |
2023-08-12 |
human |
| L Costa, C Trovato, S A Musumeci, M V Catania, L Cirann. 5-HT(1A) and 5-HT(7) receptors differently modulate AMPA receptor-mediated hippocampal synaptic transmission. Hippocampus. vol 22. issue 4. 2012-07-24. PMID:21538661. |
5-ht(1a) and 5-ht(7) receptors differently modulate ampa receptor-mediated hippocampal synaptic transmission. |
2012-07-24 |
2023-08-12 |
mouse |
| L Costa, C Trovato, S A Musumeci, M V Catania, L Cirann. 5-HT(1A) and 5-HT(7) receptors differently modulate AMPA receptor-mediated hippocampal synaptic transmission. Hippocampus. vol 22. issue 4. 2012-07-24. PMID:21538661. |
we have studied the effects of 5-ht(1a) and 5-ht(7) serotonin receptor activation in hippocampal ca3-ca1 synaptic transmission using patch clamp on mouse brain slices. |
2012-07-24 |
2023-08-12 |
mouse |
| Katsuyoshi Mizukami, Masanori Ishikawa, Hiroyasu Akatsu, Eric E Abrahamson, Milos D Ikonomovic, Takashi Asad. An immunohistochemical study of the serotonin 1A receptor in the hippocampus of subjects with Alzheimer's disease. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 31. issue 5. 2012-07-23. PMID:21269332. |
an immunohistochemical study of the serotonin 1a receptor in the hippocampus of subjects with alzheimer's disease. |
2012-07-23 |
2023-08-12 |
human |