| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Katharine Herrick-Davis, Ellinor Grinde, Tara Lindsley, Ann Cowan, Joseph E Mazurkiewic. Oligomer size of the serotonin 5-hydroxytryptamine 2C (5-HT2C) receptor revealed by fluorescence correlation spectroscopy with photon counting histogram analysis: evidence for homodimers without monomers or tetramers. The Journal of biological chemistry. vol 287. issue 28. 2012-10-09. PMID:22593582. |
fcs was used to record fluctuations in fluorescence intensity arising from fluorescence-tagged 5-hydroxytryptamine 2c (5-ht(2c)) receptors diffusing within the plasma membrane of hek293 cells and rat hippocampal neurons. |
2012-10-09 |
2023-08-12 |
rat |
| J R Seckl, K L Dickson, G Fin. Central 5,7-dihydroxytryptamine lesions decrease hippocampal glucocorticoid and mineralocorticoid receptor messenger ribonucleic Acid expression. Journal of neuroendocrinology. vol 2. issue 6. 2012-10-02. PMID:19215437. |
there is an extensive serotoninergic (5-ht) innervation of the hippocampus which interacts with corticosteroid-sensitive cells. |
2012-10-02 |
2023-08-12 |
rat |
| J R Seckl, K L Dickson, G Fin. Central 5,7-dihydroxytryptamine lesions decrease hippocampal glucocorticoid and mineralocorticoid receptor messenger ribonucleic Acid expression. Journal of neuroendocrinology. vol 2. issue 6. 2012-10-02. PMID:19215437. |
we have investigated the effect of intracerebroventricular 5,7-dihydroxytryptamine lesions of 5-ht neurons on glucocorticoid and mineralocorticoid receptor messenger ribonucleic acid (mrna) expression in the rat hippocampus using in situ hybridization histochemistry. |
2012-10-02 |
2023-08-12 |
rat |
| J R Seckl, K L Dickson, G Fin. Central 5,7-dihydroxytryptamine lesions decrease hippocampal glucocorticoid and mineralocorticoid receptor messenger ribonucleic Acid expression. Journal of neuroendocrinology. vol 2. issue 6. 2012-10-02. PMID:19215437. |
thus the 5-ht innervation regulates hippocampal corticosteroid receptor mrna expression. |
2012-10-02 |
2023-08-12 |
rat |
| M Fekete, G Hartmann, D Zakirov, L Halvax, K Lissá. Effect of dopamine on the hypothalamo-pituitary-adrenocortical system after injection in the nucleus raphe dorsalis. Neuroscience letters. vol 4. issue 3-4. 2012-10-02. PMID:19604944. |
dopamine (da) injected into the dorsal raphe nucleus (drn) increased plasma corticosterone (pcs) level as well as serotonin (5-ht) content in the mesencephalon and hippocampus 30 min after the administration. |
2012-10-02 |
2023-08-12 |
rat |
| M Fekete, G Hartmann, D Zakirov, L Halvax, K Lissá. Effect of dopamine on the hypothalamo-pituitary-adrenocortical system after injection in the nucleus raphe dorsalis. Neuroscience letters. vol 4. issue 3-4. 2012-10-02. PMID:19604944. |
pcs level and 5-ht content of the hypothalamus in da-treated + stressed animals did not differ from the values found in da-treated rats, but mesencephalic and hippocampal 5-ht content did not increase. |
2012-10-02 |
2023-08-12 |
rat |
| B E Sumner, R Rosie, G Fin. Relative density of 5-hydroxytryptamine receptor subtype mRNAs in female rat neuroendocrine brain determined by in situ hybridization histochemistry. Molecular and cellular neurosciences. vol 3. issue 3. 2012-10-02. PMID:19912863. |
in other brain regions the highest contents of 5-ht(1a), 5-ht(1c), and 5-ht(2) receptor mrnas were found in hippocampus, choroid plexus, and cingulate and frontal cortices, respectively. |
2012-10-02 |
2023-08-12 |
rat |
| M Hamon, D L Nelson, M Mallat, S Bourgoi. Are 5-HT receptors involved in the sprouting of serotoninergic terminals following neonatal 5,7-dihydroxytryptamine treatment in the rat? Neurochemistry international. vol 3. issue 1. 2012-10-02. PMID:20487810. |
the neonatal administration of 5,7-dihydroxytryptamine to rats (100 mg kg(?1) s.c. on the 1st and 2nd day after birth) resulted in marked reductions in serotoninergic presynaptic markers ([(3)h]-5-ht synaptosomal uptake, tryptophan hydroxylase activity and endogenous 5-ht content) in various forebrain areas, particularly the cerebral cortex and the hippocampus. |
2012-10-02 |
2023-08-12 |
rat |
| G Szabó, G L Kovács, L Baláspiri, G Telegd. Dose-related effect of the oxytocin fragment (prolyl-leucyl-glycinamide) on ?-MPT-induced catecholamine disappearance and serotonin level in rat brain. Neurochemistry international. vol 3. issue 6. 2012-10-02. PMID:20487841. |
the serotonin level was increased in the hypothalamus, in the striatum and decreased in the dorsal hippocampus. |
2012-10-02 |
2023-08-12 |
rat |
| E Azmitia, M J Brennan, D Quartermai. Adult development of the hippocampal-serotonin system of C57BL/6N mice; analysis of high-affinity uptake of (3)H-5HT in slices and synaptosomes. Neurochemistry international. vol 5. issue 1. 2012-10-02. PMID:20487920. |
the saturable and specific high-affinity uptake of [(3)h]serotonin ([(3)h]5ht) (5 x 10(?8) m) was studied in slices from the hippocampus, parietal cortex, septum-preoptic area, and hypothalamus of male 2, 6, 12 and 24-32 month old c57bl/6n mice. |
2012-10-02 |
2023-08-12 |
mouse |
| E Azmitia, M J Brennan, D Quartermai. Adult development of the hippocampal-serotonin system of C57BL/6N mice; analysis of high-affinity uptake of (3)H-5HT in slices and synaptosomes. Neurochemistry international. vol 5. issue 1. 2012-10-02. PMID:20487920. |
hippocampal [(3)h]5-ht uptake showed a significant biphasic relationship to age, with lower values in the 2 and 24-32 month old mice compared to 6 month old mice. |
2012-10-02 |
2023-08-12 |
mouse |
| E Azmitia, M J Brennan, D Quartermai. Adult development of the hippocampal-serotonin system of C57BL/6N mice; analysis of high-affinity uptake of (3)H-5HT in slices and synaptosomes. Neurochemistry international. vol 5. issue 1. 2012-10-02. PMID:20487920. |
kinetic analysis of the [(3)h]5ht high-affinity uptake in the hippocampus (3 min, 37 degrees c) revealed the same apparent k(m) for serotonin at both ages (6.7 x 10(?8) m), but a 44% decrease in v(max) in the aged hippocampal synaptosomal high-affinity uptake compared to adults (120 vs 215 pmol of 5-ht/g-tissue/3 min). |
2012-10-02 |
2023-08-12 |
mouse |
| C Goetz, S Bourgoin, F Cesselin, A Brandi, D Bression, M Martinet, F Peillon, M Hamo. Alterations in central neurotransmitter receptor binding sites following estradiol implantation in female rats. Neurochemistry international. vol 5. issue 4. 2012-10-02. PMID:20487964. |
examination of neurotransmitter receptors in the hippocampus, striatum and cerebral cortex one month after the implantation revealed that estrogenization was associated with: an increased density of (3)h-domperidone binding sites (d(2) receptors) in the striatum and reduced numbers of (3)h-serotonin high affinity sites (5-ht(1) receptors) in the hippocampus and of (3)h-muscimol binding sites (gaba receptors) in the hippocampus, striatum and cerebral cortex. |
2012-10-02 |
2023-08-12 |
rat |
| M C Boadle-Biber, J N Johannessen, N Narasimhachari, T H Pha. Tryptophan hydroxylase: increase in activity by electrical stimulation of serotonergic neurons. Neurochemistry international. vol 8. issue 1. 2012-10-02. PMID:20493033. |
in contrast, activity of enzyme from hippocampus, which receives its 5-ht innervation primarily from the median raphe was unaffected by dorsal raphe stimulation. |
2012-10-02 |
2023-08-12 |
rat |
| P E Potter, L G Harsing, I Kakucska, G Gaal, E S Viz. Selective impairment of acetylcholine release and content in the central nervous system following intracerebroventricular administration of ethylcholine mustard aziridinium ion (AF64A) in the rat. Neurochemistry international. vol 8. issue 2. 2012-10-02. PMID:20493047. |
non-specific changes in hippocampal levels of dopamine, noradrenaline and 5-hydroxytryptamine were also observed. |
2012-10-02 |
2023-08-12 |
rat |
| P E Potter, L G Harsing, I Kakucska, G Gaal, E S Viz. Selective impairment of acetylcholine release and content in the central nervous system following intracerebroventricular administration of ethylcholine mustard aziridinium ion (AF64A) in the rat. Neurochemistry international. vol 8. issue 2. 2012-10-02. PMID:20493047. |
although there was a transient reduction in hippocampal 5-hydroxytryptamine content 4 days after treatment, this had recovered to control levels within 7 days. |
2012-10-02 |
2023-08-12 |
rat |
| A J Cross, G P Reynolds, L M Hewitt, P Slate. Brain serotonin receptors in Huntington's disease. Neurochemistry international. vol 9. issue 3. 2012-10-02. PMID:20493143. |
significant reductions in serotonin s1 receptors were observed in putamen and hippocampus but not in frontal and temporal cortices. |
2012-10-02 |
2023-08-12 |
Not clear |
| L Kiedrowski, M Gra Dkowska, B Oderfeld-Nowa. Time dependent effect of GM, ganglioside administration upon [(3)H]5-hydroxytryptamine uptake in partially denervated rat hippocampus. Neurochemistry international. vol 10. issue 2. 2012-10-02. PMID:20501070. |
time dependent effect of gm, ganglioside administration upon [(3)h]5-hydroxytryptamine uptake in partially denervated rat hippocampus. |
2012-10-02 |
2023-08-12 |
rat |
| L Kiedrowski, M Gra Dkowska, B Oderfeld-Nowa. Time dependent effect of GM, ganglioside administration upon [(3)H]5-hydroxytryptamine uptake in partially denervated rat hippocampus. Neurochemistry international. vol 10. issue 2. 2012-10-02. PMID:20501070. |
this effect was limited to the most denervated dorsal hippocampal part, where the lesion-evoked decrease of [(3)h]5-hydroxytryptamine uptake was the strongest. |
2012-10-02 |
2023-08-12 |
rat |
| L Kiedrowski, M Gra Dkowska, B Oderfeld-Nowa. Time dependent effect of GM, ganglioside administration upon [(3)H]5-hydroxytryptamine uptake in partially denervated rat hippocampus. Neurochemistry international. vol 10. issue 2. 2012-10-02. PMID:20501070. |
on the other hand, prolonged gm(1) administration (21-90 days) to unoperated animals caused a small but significant reduction of [(3)h]5-hydroxytryptamine uptake, equal in all three hippocampal parts. |
2012-10-02 |
2023-08-12 |
rat |