| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Woods, N N Clarke, R Layfield, K C F Fon. 5-HT(6) receptor agonists and antagonists enhance learning and memory in a conditioned emotion response paradigm by modulation of cholinergic and glutamatergic mechanisms. British journal of pharmacology. vol 167. issue 2. 2013-01-07. PMID:22568655. |
5-ht(6) receptors are abundant in the hippocampus, nucleus accumbens and striatum, supporting their role in learning and memory. |
2013-01-07 |
2023-08-12 |
Not clear |
| Charles Prisila Dulcy, Hemant K Singh, Jayakumar Preethi, Koilmani Emmanuvel Raja. Standardized extract of Bacopa monniera (BESEB CDRI-08) attenuates contextual associative learning deficits in the aging rat's brain induced by D-galactose. Journal of neuroscience research. vol 90. issue 10. 2013-01-04. PMID:22715050. |
subsequent analysis showed that the bme administration significantly decreased advance glycation end product (age) in serum and increased the activity of antioxidant response element (are) and the antioxidant enzymes superoxide dismutase (sod), glutathione peroxidase (gsh-px), and nuclear transcription factor nf-e2-related factor 2 (nrf2), accompanied by a reduction in the level of serotonin (5-ht) in the hippocampus. |
2013-01-04 |
2023-08-12 |
rat |
| Saida Haider, Fizza Naqvi, Zehra Batool, Saiqa Tabassum, Tahira Perveen, Sadia Saleem, Darakhshan Jabeen Halee. Decreased Hippocampal 5-HT and DA Levels Following Sub-Chronic Exposure to Noise Stress: Impairment in both Spatial and Recognition Memory in Male Rats. Scientia pharmaceutica. vol 80. issue 4. 2012-12-25. PMID:23264946. |
decreased hippocampal 5-ht and da levels following sub-chronic exposure to noise stress: impairment in both spatial and recognition memory in male rats. |
2012-12-25 |
2023-08-12 |
rat |
| Saida Haider, Fizza Naqvi, Zehra Batool, Saiqa Tabassum, Tahira Perveen, Sadia Saleem, Darakhshan Jabeen Halee. Decreased Hippocampal 5-HT and DA Levels Following Sub-Chronic Exposure to Noise Stress: Impairment in both Spatial and Recognition Memory in Male Rats. Scientia pharmaceutica. vol 80. issue 4. 2012-12-25. PMID:23264946. |
the data obtained revealed a significant decrease in hippocampal serotonin (5-hydroxytryptamine; 5-ht) and dopamine (da) levels, whereas turnover ratios of 5-ht and da were significantly increased compared to the controls. |
2012-12-25 |
2023-08-12 |
rat |
| Saida Haider, Fizza Naqvi, Zehra Batool, Saiqa Tabassum, Tahira Perveen, Sadia Saleem, Darakhshan Jabeen Halee. Decreased Hippocampal 5-HT and DA Levels Following Sub-Chronic Exposure to Noise Stress: Impairment in both Spatial and Recognition Memory in Male Rats. Scientia pharmaceutica. vol 80. issue 4. 2012-12-25. PMID:23264946. |
results of the present findings suggest the role of decreased hippocampal 5-ht and da in the impairment of cognitive function following noise exposure. |
2012-12-25 |
2023-08-12 |
rat |
| Miki Yamauchi, Taiichiro Imanishi, Tsukasa Koyam. A combination of mirtazapine and milnacipran augments the extracellular levels of monoamines in the rat brain. Neuropharmacology. vol 62. issue 7. 2012-12-20. PMID:22342987. |
mirtazapine increased the extracellular levels of noradrenaline and serotonin in the dorsal hippocampus. |
2012-12-20 |
2023-08-12 |
rat |
| Daria Peleg-Raibstein, Edlira Luca, Christian Wolfru. Maternal high-fat diet in mice programs emotional behavior in adulthood. Behavioural brain research. vol 233. issue 2. 2012-12-10. PMID:22633920. |
in addition, brain-derived neurotrophic factor (bdnf) was significantly increased in the dorsal hippocampus, while gaba(a) alpha2 receptor subunit and 5-hydroxytryptamine 1a (5-ht1a) receptor showed increased levels in the ventral hippocampus. |
2012-12-10 |
2023-08-12 |
mouse |
| Yongsoon Park, Hyoun-Jung Moon, Seok-Hyeon Ki. N-3 polyunsaturated fatty acid consumption produces neurobiological effects associated with prevention of depression in rats after the forced swimming test. The Journal of nutritional biochemistry. vol 23. issue 8. 2012-12-07. PMID:21852084. |
plasma serotonin concentration and hippocampus c-amp response element binding protein (creb) expression were significantly increased in the 0.5% and 1% epa+dha groups compared with those in the 0% epa+dha group. |
2012-12-07 |
2023-08-12 |
rat |
| Kenji F Tanaka, Benjamin Adam Samuels, René He. Serotonin receptor expression along the dorsal-ventral axis of mouse hippocampus. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 367. issue 1601. 2012-12-06. PMID:22826340. |
using in situ hybridization, we describe, for the first time, the profiles of expression of serotonin receptors (htr/5-htr) along the dorsal-ventral axis of mouse hippocampus. |
2012-12-06 |
2023-08-12 |
mouse |
| Kenji F Tanaka, Benjamin Adam Samuels, René He. Serotonin receptor expression along the dorsal-ventral axis of mouse hippocampus. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 367. issue 1601. 2012-12-06. PMID:22826340. |
four serotonin receptors, htr1a, htr2a, htr2c and htr7, display an expression pattern that changes along the dorsal-ventral axis of the hippocampus. |
2012-12-06 |
2023-08-12 |
mouse |
| Kenji F Tanaka, Benjamin Adam Samuels, René He. Serotonin receptor expression along the dorsal-ventral axis of mouse hippocampus. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 367. issue 1601. 2012-12-06. PMID:22826340. |
given the proposed functional differentiation of the hippocampus along its long axis, with the dorsal pole more involved in cognitive functions and the ventral pole more involved in mood and anxiety, our results suggest that serotonin receptors enriched in the ventral pole probably contribute to mood- and anxiety-related behaviours. |
2012-12-06 |
2023-08-12 |
mouse |
| Ian C Hellstrom, Sabine K Dhir, Josie C Diorio, Michael J Meane. Maternal licking regulates hippocampal glucocorticoid receptor transcription through a thyroid hormone-serotonin-NGFI-A signalling cascade. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 367. issue 1601. 2012-12-06. PMID:22826348. |
in this paper, we report that: (i) the association of ngfi-a with the exon 1(7) gr promoter is dynamically regulated by mother-pup interactions; (ii) this effect is mimicked by artificial tactile stimulation comparable to that provided by pup lg; (iii) that serotonin (5-ht) induces an ngfi-a-dependent increase in gr transcription in hippocampal neurons and ngfi-a overexpression is sufficient for this effect; and (iv) that thyroid hormones and 5-ht are key mediators of the effects of pup lg and tactile stimulation on ngfi-a binding to the exon 1(7) gr promoter in hippocampus. |
2012-12-06 |
2023-08-12 |
rat |
| Ian C Hellstrom, Sabine K Dhir, Josie C Diorio, Michael J Meane. Maternal licking regulates hippocampal glucocorticoid receptor transcription through a thyroid hormone-serotonin-NGFI-A signalling cascade. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 367. issue 1601. 2012-12-06. PMID:22826348. |
these findings suggest that pup lg directly activates 5-ht systems to initiate intracellular signalling pathways in the hippocampus that regulate gr transcription. |
2012-12-06 |
2023-08-12 |
rat |
| Ute Renner, Andre Zeug, Andrew Woehler, Marcus Niebert, Alexander Dityatev, Galina Dityateva, Nataliya Gorinski, Daria Guseva, Dalia Abdel-Galil, Matthias Fröhlich, Frank Döring, Erhard Wischmeyer, Diethelm W Richter, Erwin Neher, Evgeni G Ponimaski. Heterodimerization of serotonin receptors 5-HT1A and 5-HT7 differentially regulates receptor signalling and trafficking. Journal of cell science. vol 125. issue Pt 10. 2012-12-03. PMID:22357950. |
finally, we found that production of 5-ht(7) receptors in the hippocampus continuously decreases during postnatal development, indicating that the relative concentration of 5-ht(1a)-5-ht(7) heterodimers and, consequently, their functional importance undergoes pronounced developmental changes. |
2012-12-03 |
2023-08-12 |
Not clear |
| Francis Rodriguez Bambico, Patrick R Hattan, Jean-Philippe Garant, Gabriella Gobb. Effect of delta-9-tetrahydrocannabinol on behavioral despair and on pre- and postsynaptic serotonergic transmission. Progress in neuro-psychopharmacology & biological psychiatry. vol 38. issue 1. 2012-12-03. PMID:22386778. |
finally, repeated but not single delta-9-thc administration (1mg/kg, ip) enhanced tonic 5-ht(1a) receptor activity in the hippocampus, a postsynaptic event commonly elicited by standard antidepressants. |
2012-12-03 |
2023-08-12 |
rat |
| Francis Rodriguez Bambico, Patrick R Hattan, Jean-Philippe Garant, Gabriella Gobb. Effect of delta-9-tetrahydrocannabinol on behavioral despair and on pre- and postsynaptic serotonergic transmission. Progress in neuro-psychopharmacology & biological psychiatry. vol 38. issue 1. 2012-12-03. PMID:22386778. |
these results suggest that delta-9-thc, like other cb(1)r agonists and endocannabinoid enhancers, may possess antidepressant properties at low doses, and could modulate 5-ht transmission in the dr and hippocampus as standard antidepressants such as selective serotonin reuptake inhibitors. |
2012-12-03 |
2023-08-12 |
rat |
| G Ulrich-Merzenich, O Kelber, A Koptina, A Freischmidt, J Heilmann, J Müller, H Zeitler, M F Seidel, M Ludwig, E U Heinrich, H Winterhof. Novel neurological and immunological targets for salicylate-based phytopharmaceuticals and for the anti-depressant imipramine. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 19. issue 10. 2012-12-03. PMID:22743246. |
in addition, the hippocampus of rats treated (27 d) with wb (15-60 mg/kg wb) or imipramine (15 mg/kg bw) showed a slower serotonin turnover (5-hydroxyindol acetic acid/serotonin (p<0.05)) depending on the dosage. |
2012-12-03 |
2023-08-12 |
rat |
| Daniela M Pechlivanova, Jana D Tchekalarova, Liana H Alova, Vesselin V Petkov, Rumen P Nikolov, Krassimira S Yakimov. Effect of long-term caffeine administration on depressive-like behavior in rats exposed to chronic unpredictable stress. Behavioural pharmacology. vol 23. issue 4. 2012-12-03. PMID:22785384. |
in cus-exposed rats, caffeine showed antidepressant and anxiolytic activity, accompanied by increased hippocampal dopamine and serotonin levels. |
2012-12-03 |
2023-08-12 |
rat |
| Katherine M Nautiyal, Christopher A Dailey, Jaquelyn L Jahn, Elizabeth Rodriquez, Nguyen Hong Son, Jonathan V Sweedler, Rae Silve. Serotonin of mast cell origin contributes to hippocampal function. The European journal of neuroscience. vol 36. issue 3. 2012-11-30. PMID:22632453. |
serotonin of mast cell origin contributes to hippocampal function. |
2012-11-30 |
2023-08-12 |
mouse |
| Katherine M Nautiyal, Christopher A Dailey, Jaquelyn L Jahn, Elizabeth Rodriquez, Nguyen Hong Son, Jonathan V Sweedler, Rae Silve. Serotonin of mast cell origin contributes to hippocampal function. The European journal of neuroscience. vol 36. issue 3. 2012-11-30. PMID:22632453. |
measurements based on capillary electrophoresis with native fluorescence detection indicate that a significant contribution of serotonin to the hippocampal milieu is associated with mast cell activation. |
2012-11-30 |
2023-08-12 |
mouse |