| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sadia Basharat Ali, Raheel Saeed, Khalid Mahmood, Darakhshan Jabeen Halee. Omeprazole affects the expression of serotonin-1A in the brain regions and alleviates anxiety in rat model of immobilization-induced stress. Behavioural pharmacology. 2024-09-04. PMID:39230572. |
similarly, because of the role of hippocampal 5-ht neurotransmission in anxiety-like disorders, expression of the 5-ht1a heteroreceptors was determined in this region. |
2024-09-04 |
2024-09-06 |
rat |
| Mani Surya Kumar Palepu, Harshada Anil Bhalerao, Rajesh Sonti, Manoj P Dandeka. Faecalibacterium prausnitzii, FOS and GOS Loaded Synbiotic Reverses Treatment-resistant Depression in rats: Restoration of Gut-Brain Crosstalk. European journal of pharmacology. 2024-08-30. PMID:39214274. |
it normalized the altered levels of key neurotransmitters such as serotonin, gamma-aminobutyric acid, noradrenaline, and dopamine in the hippocampus and/or frontal cortex. |
2024-08-30 |
2024-09-04 |
rat |
| Nosarieme Omoregie Abey, Osaretin Albert Taiwo Ebuehi, Ngozi Awa Imag. Effect of perinatal dietary protein deficiency on some neurochemicals and cytoarchitectural balance, in F1 and F2 generations of rats. Nutritional neuroscience. vol 27. issue 9. 2024-08-27. PMID:37995096. |
the protein-deficient groups displayed anxiety, loss of striatal serotonin and increased dopamine levels, degenerated pyramidal cells in the hippocampus, and a prominent reduction in cellular density in the pfc. |
2024-08-27 |
2024-08-30 |
rat |
| Fei Fei, Ziwei Chen, Yi Tao, Xinliang Jiang, Xinyue Xu, Yifeng Ma, Peishi Feng, Ping Wan. Comparison of CUMS at different pregnancy stages, maternal separation, and their effects on offspring in postpartum depression mouse models. Heliyon. vol 10. issue 15. 2024-08-21. PMID:39166014. |
the models were deemed effective based on observed behavioral abnormalities, impaired hippocampal neuron functioning, and reduced serum concentrations of neurotransmitters (5-ht, gaba, and ne). |
2024-08-21 |
2024-08-23 |
mouse |
| Paige L Graney, Evelyn L Sarno, Jessie E Miller, Christine K Wagne. Implications of Developmental 17-OHPC Exposure on the Mesocorticolimbic Serotonergic and Dopaminergic Pathways and Adolescent Mood-Related Behavior in Rats. Developmental psychobiology. vol 66. issue 6. 2024-08-21. PMID:39164823. |
developmental 17-ohpc exposure significantly increased the density of serotonin transporter-ir fibers in ca1, ca2/3, and the suprapyramidal blade of dentate gyrus in hippocampus and significantly reduced the density of th-ir fibers within the nucleus accumbens shell in males but had no effect in females during adolescence. |
2024-08-21 |
2024-08-23 |
rat |
| Po-Yu Chien, Chun-Lin Su, Pei-Hua Liu, Chih-Hua Chang, Po-Wu Gea. The dorsal raphe-to-ventral hippocampal projection modulates reactive aggression through 5HT European journal of pharmacology. 2024-08-19. PMID:39159717. |
the dorsal raphe-to-ventral hippocampal projection modulates reactive aggression through 5ht maladaptive impulsive aggression is a core symptom of neuropsychiatric disorders such as schizophrenia. |
2024-08-19 |
2024-08-22 |
mouse |
| Yan-Bin Wei, Yong-Bo Wang, Jia-Yue Sun, Shan Wang, Jun Nan, Hai-Ling Yu, Yan La. N-palmitoylethanolamide attenuates negative emotions induced by morphine withdrawal in mice. Neuroscience letters. 2024-08-18. PMID:39154843. |
the findings indicate that pea mitigated anxiety and depression symptoms and reduced 5-hydroxytryptamine, noradrenaline, and dopamine levels in the hippocampus and prefrontal cortex. |
2024-08-18 |
2024-08-21 |
mouse |
| Cailing Chen, Zhiyao Zheng, Kan Gao, Qiuling Fan, Yanjun Li, Su Che. Prophylactic effects of supplementation of a combination of Lactobacillus lactis WHH2078 and saffron on depressive-like behaviors in mice exposed to chronic stress. Journal of food science. 2024-08-10. PMID:39126686. |
in this study, three natural products (saffron, l-theanine, and phosphatidylserine), either individually or in combination, were orally administrated for 4 weeks in chronic restraint stress (crs)-induced mice, and their depressive behaviors, hippocampal 5-ht, and serum corticosterone were assessed. |
2024-08-10 |
2024-08-13 |
mouse |
| Cailing Chen, Zhiyao Zheng, Kan Gao, Qiuling Fan, Yanjun Li, Su Che. Prophylactic effects of supplementation of a combination of Lactobacillus lactis WHH2078 and saffron on depressive-like behaviors in mice exposed to chronic stress. Journal of food science. 2024-08-10. PMID:39126686. |
compared to whh2078, whhmood treatment significantly increased the travel distance and hippocampal 5-ht level in mice. |
2024-08-10 |
2024-08-13 |
mouse |
| Shi Bai, Zhong-Ming Ying, Jia-Kang Ying, Qin-Ying Zhang, Yu-Hang Lv, Zhong-Min W. Inhibition of 5-HT alleviates PTSD-like behaviors and promotes hippocampal neuroplasticity by modulating hippocampal autophagy in rats. Journal of neurophysiology. 2024-08-07. PMID:39110517. |
inhibition of 5-ht alleviates ptsd-like behaviors and promotes hippocampal neuroplasticity by modulating hippocampal autophagy in rats. |
2024-08-07 |
2024-08-10 |
rat |
| Shi Bai, Zhong-Ming Ying, Jia-Kang Ying, Qin-Ying Zhang, Yu-Hang Lv, Zhong-Min W. Inhibition of 5-HT alleviates PTSD-like behaviors and promotes hippocampal neuroplasticity by modulating hippocampal autophagy in rats. Journal of neurophysiology. 2024-08-07. PMID:39110517. |
rats exposed to single prolonged stress (sps) exhibited typical ptsd-like phenotypes, with decreased levels of 5-ht in the hippocampus and significant reductions in its downstream targets, brain-derived neurotrophic factor (bdnf) and trkb. |
2024-08-07 |
2024-08-10 |
rat |
| Benneth Ben-Azu, Pere-Ebi Y Toloyai, Adaeze Adebesin, Vivian O Ojiokor, Olusegun G Adebayo, Aliance Romain Fokoua, Goodes E Moke, Elo J Ejukolemu, Ife-Oluwa O Akpojevughe, Abdulkareem M Abdulkadir, Ephraim Okwuch. Alcohol-exacerbates post-traumatic stress psychiatric behavior and its neuropathological sequalae in experimental mice: preventive effects of morin. Alcohol (Fayetteville, N.Y.). 2024-08-02. PMID:39094850. |
sps-ethanol exacerbates dopamine, serotonin, and glutamic acid decarboxylase alterations, and monoamine oxidase-b and acetylcholinesterase hyperactivities in the striatum, pfc, and hippocampus, respectively, which were prevented by morin. |
2024-08-02 |
2024-08-06 |
mouse |
| Qian-Yun Wu, Lian-Hong Lin, Kun Lu, Si-Fu Deng, Wei-Min Li, Yuan Xu, Bin Zhang, Ji-Hong Li. Astrocytic 5-HT Experimental & molecular medicine. 2024-07-31. PMID:39085354. |
astrocytic 5-ht nmda receptor-dependent long-term depression (ltd) in the hippocampus is a well-known form of synaptic plasticity that has been linked to different cognitive functions. |
2024-07-31 |
2024-08-03 |
mouse |
| Michael Murack, Anthony K Kadamani, Alexi Guindon-Riopel, Olivia H Traynor, Umar Haris Iqbal, Stéphane Bronner, Claude Messier, Nafissa Ismai. The effect of probiotic supplementation on sleep, depression-like behaviour, and central glucose and lactate metabolism in male and female pubertal mice exposed to chronic sleep disruption. Psychoneuroendocrinology. vol 168. 2024-07-30. PMID:39079447. |
cerebiome prevented decreases to prefrontal serotonin and hippocampal glucose concentrations, while lacidofil increased nrem duration in the latter half of the light phase. |
2024-07-30 |
2024-08-02 |
mouse |
| Zhen Lyu, Zhi-Gang Gong, Min-Xia Huang, Si-Ping Xin, Mao-Zhong Zou, Yu-Quan Din. Benefits of exercise on cognitive impairment in alcohol use disorder following alcohol withdrawal. FEBS open bio. 2024-07-25. PMID:39054261. |
the levels of dopamine, norepinephrine, serotonin, and brain-derived neurotrophic factor in the hippocampus were quantified using enzyme-linked immunoassay (elisa) kits. |
2024-07-25 |
2024-07-28 |
mouse |
| Igor Henrique Rodrigues de Paiva, Rodrigo Soares da Silva, Ingrid Prata Mendonça, José Roberto Botelho de Souza, Christina Alves Peixot. Semaglutide Attenuates Anxious and Depressive-Like Behaviors and Reverses the Cognitive Impairment in a Type 2 Diabetes Mellitus Mouse Model Via the Microbiota-Gut-Brain Axis. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 19. issue 1. 2024-07-23. PMID:39042202. |
our data also showed that semaglutide increased the serotonin (5-ht) and serotonin transporter (5-htt) and glutamatergic receptors in the hippocampus. |
2024-07-23 |
2024-07-25 |
mouse |
| Allison K Warner, Lauren Iskander, Kristen Allen, Isabella Quatela, Hannah Borrelli, Benjamin D Sach. The Effects of Brain Serotonin Deficiency on the Behavioral and Neurogenesis-Promoting Effects of Voluntary Exercise in Tryptophan Hydroxylase 2 (R439H) Knock-in Mice. Neuropharmacology. 2024-07-15. PMID:39009217. |
one neurotransmitter that has been implicated in both antidepressant-like effects and the regulation of hippocampal neurogenesis is serotonin (5-ht). |
2024-07-15 |
2024-07-18 |
mouse |
| Allison K Warner, Lauren Iskander, Kristen Allen, Isabella Quatela, Hannah Borrelli, Benjamin D Sach. The Effects of Brain Serotonin Deficiency on the Behavioral and Neurogenesis-Promoting Effects of Voluntary Exercise in Tryptophan Hydroxylase 2 (R439H) Knock-in Mice. Neuropharmacology. 2024-07-15. PMID:39009217. |
however, genetic reductions in 5-ht synthesis did not significantly impact exercise-induced alterations in cellular proliferation or immature neuron production in the hippocampus in either sex. |
2024-07-15 |
2024-07-18 |
mouse |
| Liesl Maria Fernandes E Mendonça, Arun Bhimrao Joshi, Anant Bhandarkar, Shamshad Shaikh, Samantha Fernandes, Himanshu Joshi, Shrinivas Josh. Potential anxiolytic therapeutics from Hybanthus enneaspermus (L.) F. Muell. - mitigate anxiety by plausibly modulating the GABA Neurochemistry international. 2024-07-13. PMID:39002759. |
monoamines (serotonin, noradrenaline, dopamine), gamma-aminobutyric acid (gaba), and glutamate were quantified in the different regions of rats' brain (cortex, hippocampus, pons, medulla oblongata, cerebellum). |
2024-07-13 |
2024-07-16 |
rat |
| Aldo R Tejeda-Martínez, Ana R Ramos-Molina, Patricia A Brand-Rubalcava, Mario E Flores-Sot. Involvement of serotonergic receptors in depressive processes and their modulation by β-arrestins: A review. Medicine. vol 103. issue 28. 2024-07-12. PMID:38996114. |
disorders such as anxiety, depression, schizophrenia, epilepsy, sexual disorders, and eating disorders, have been closely linked to variations in 5-ht concentrations and modifications in brain structures, including the raphe nuclei (rn), prefrontal cortex, basal ganglia, hippocampus, and hypothalamus, among others. |
2024-07-12 |
2024-07-15 |
Not clear |