| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Katherine M Nautiyal, Christopher A Dailey, Jaquelyn L Jahn, Elizabeth Rodriquez, Nguyen Hong Son, Jonathan V Sweedler, Rae Silve. Serotonin of mast cell origin contributes to hippocampal function. The European journal of neuroscience. vol 36. issue 3. 2012-11-30. PMID:22632453. |
chronic treatment with fluoxetine, a selective serotonin reuptake inhibitor, reverses the deficit in hippocampal neurogenesis in mast cell-deficient mice. |
2012-11-30 |
2023-08-12 |
mouse |
| F M Farias, C S Passos, M D Arbo, D M Barros, C Gottfried, V M Steffen, A T Henrique. Strictosidinic acid, isolated from Psychotria myriantha Mull. Arg. (Rubiaceae), decreases serotonin levels in rat hippocampus. Fitoterapia. vol 83. issue 6. 2012-11-29. PMID:22546150. |
(rubiaceae), decreases serotonin levels in rat hippocampus. |
2012-11-29 |
2023-08-12 |
rat |
| F M Farias, C S Passos, M D Arbo, D M Barros, C Gottfried, V M Steffen, A T Henrique. Strictosidinic acid, isolated from Psychotria myriantha Mull. Arg. (Rubiaceae), decreases serotonin levels in rat hippocampus. Fitoterapia. vol 83. issue 6. 2012-11-29. PMID:22546150. |
the results indicate that strictosidinic acid seems to act on 5-ht system in rat hippocampus, possibly inhibiting precursor enzymes of 5-ht biosynthesis. |
2012-11-29 |
2023-08-12 |
rat |
| Krzysztof Tokarski, Agnieszka Zelek-Molik, Beata Duszyńska, Grzegorz Satała, Bartosz Bobula, Magdalena Kusek, Piotr Chmielarz, Irena Nalepa, Grzegorz Hes. Acute and repeated treatment with the 5-HT7 receptor antagonist SB 269970 induces functional desensitization of 5-HT7 receptors in rat hippocampus. Pharmacological reports : PR. vol 64. issue 2. 2012-11-23. PMID:22661174. |
the present work was aimed at examining the effect of single and repeated (14 days) administration of sb 269970 on the 5-ht(7) receptor in the hippocampus. |
2012-11-23 |
2023-08-12 |
rat |
| Jenny Molet, Elodie Bouaziz, Michel Hamon, Laurence Lanfume. Early exposure to ethanol differentially affects ethanol preference at adult age in two inbred mouse strains. Neuropharmacology. vol 63. issue 2. 2012-11-19. PMID:22521807. |
in contrast, early ethanol ingestion by c57bl/6j mice transiently lowered spontaneous ethanol consumption and increased g protein coupling of postsynaptic 5-ht(1a) receptors in the hippocampus but had no effect on cb1 receptors at adulthood. |
2012-11-19 |
2023-08-12 |
mouse |
| Masatoshi Nagano, Mingyan Liu, Hirofumi Inagaki, Tomoyuki Kawada, Hidenori Suzuk. Early intervention with fluoxetine reverses abnormalities in the serotonergic system and behavior of rats exposed prenatally to dexamethasone. Neuropharmacology. vol 63. issue 2. 2012-11-19. PMID:22710353. |
in the present study, we found abnormalities in serotonin (5-ht) signaling, including decreased expression of 5-ht(1a) receptor (5-ht(1a)-r) mrna in the medial prefrontal cortex (mpfc) and 5-ht content in the hippocampus at postnatal week (pw) 4. |
2012-11-19 |
2023-08-12 |
rat |
| Masatoshi Nagano, Mingyan Liu, Hirofumi Inagaki, Tomoyuki Kawada, Hidenori Suzuk. Early intervention with fluoxetine reverses abnormalities in the serotonergic system and behavior of rats exposed prenatally to dexamethasone. Neuropharmacology. vol 63. issue 2. 2012-11-19. PMID:22710353. |
likewise, flx increased 5-ht concentrations in the mpfc and ventral hippocampus at pw3 and normalized 5-ht(1a)-r mrna concentrations in the mpfc at pw4. |
2012-11-19 |
2023-08-12 |
rat |
| K L Eskow Jaunarajs, J A George, C Bisho. L-DOPA-induced dysregulation of extrastriatal dopamine and serotonin and affective symptoms in a bilateral rat model of Parkinson's disease. Neuroscience. vol 218. 2012-11-16. PMID:22659568. |
in the first experiment, striatal, hippocampal, amygdalar, and prefrontal cortex da and 5-ht levels were examined at various post-treatment time-points. |
2012-11-16 |
2023-08-12 |
rat |
| Daphne Everaerd, Lotte Gerritsen, Mark Rijpkema, Thomas Frodl, Iris van Oostrom, Barbara Franke, Guillén Fernández, Indira Tendolka. Sex modulates the interactive effect of the serotonin transporter gene polymorphism and childhood adversity on hippocampal volume. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 8. 2012-11-13. PMID:22434222. |
sex modulates the interactive effect of the serotonin transporter gene polymorphism and childhood adversity on hippocampal volume. |
2012-11-13 |
2023-08-12 |
Not clear |
| Heidi Kaastrup Müller, Gregers Wegener, Betina Elfvin. Chronic restraint stress affects serotonin transporter uptake kinetics but not binding sites in the rat hippocampus. Synapse (New York, N.Y.). vol 66. issue 3. 2012-11-09. PMID:21954049. |
chronic restraint stress affects serotonin transporter uptake kinetics but not binding sites in the rat hippocampus. |
2012-11-09 |
2023-08-12 |
rat |
| Elena M Kondaurova, Vladimir S Naumenko, Nina K Popov. Effect of chronic activation of 5-HT3 receptors on 5-HT3, 5-HT(1A) and 5-HT(2A) receptors functional activity and expression of key genes of the brain serotonin system. Neuroscience letters. vol 522. issue 1. 2012-11-09. PMID:22705909. |
chronic activation of 5-ht(3) receptor produced no considerable effect on the expression on 5-ht(3), 5-ht(1a), and 5-ht transporter (5-htt) and tryptophan hydroxylase-2 (tph-2) genes - the key genes of brain 5-ht system, in the midbrain, frontal cortex and hippocampus. |
2012-11-09 |
2023-08-12 |
mouse |
| A Bortolozzi, A Castañé, J Semakova, N Santana, G Alvarado, R Cortés, A Ferrés-Coy, G Fernández, M C Carmona, M Toth, J C Perales, A Montefeltro, F Artiga. Selective siRNA-mediated suppression of 5-HT1A autoreceptors evokes strong anti-depressant-like effects. Molecular psychiatry. vol 17. issue 6. 2012-11-07. PMID:21808255. |
in parallel, c-1a-sirna administration markedly decreased 5-ht(1a)-autoreceptor expression and suppressed 8-oh-dpat-induced hypothermia (a pre-synaptic 5-ht(1a)r effect in mice) without affecting post-synaptic 5-ht(1a)r expression in hippocampus and prefrontal cortex. |
2012-11-07 |
2023-08-12 |
mouse |
| Silvia Racca, Francesca Piccione, Angela Spaccamiglio, Vitina M A Carriero, Silvia De Francia, Luigi Cangemi, Paola Esculapio, Mauro Papotti, Giuseppe Migliaretti, Paolo Portaleone, Francesco Di Carlo, Giuliana Abbadess. Effects of sub-chronic nandrolone administration on hormonal adaptive response to acute stress in rats. Psychoneuroendocrinology. vol 37. issue 8. 2012-11-05. PMID:22226432. |
acute rs produced the following effects: increase in cort (in blood) and acth (both in blood and in pituitary corticotropes), gr depletion in hippocampus and hypothalamus cytosol and gr translocation in hippocampus nuclear fraction, cortical serotonin re-uptake stimulation and hippocampus cytosolic erk2 activation. |
2012-11-05 |
2023-08-12 |
rat |
| M E Haahr, P M Rasmussen, K Madsen, L Marner, C Ratner, N Gillings, W F C Baaré, G M Knudse. Obesity is associated with high serotonin 4 receptor availability in the brain reward circuitry. NeuroImage. vol 61. issue 4. 2012-11-05. PMID:22709820. |
we found in humans a strong positive association between body mass index and the 5-ht(4)r density bilaterally in the two reward ‘hot spots’ nucleus accumbens and ventral pallidum, and additionally in the left hippocampal region and orbitofrontal cortex. |
2012-11-05 |
2023-08-12 |
Not clear |
| Wei Song, Hillel Zukor, Shih-Hsiung Lin, Jacob Hascalovici, Adrienne Liberman, Ayda Tavitian, Jeannie Mui, Hojatollah Vali, Xin-Kang Tong, Sanjeev K Bhardwaj, Lalit K Srivastava, Edith Hamel, Hyman M Schippe. Schizophrenia-like features in transgenic mice overexpressing human HO-1 in the astrocytic compartment. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 32. 2012-10-26. PMID:22875919. |
herein, we demonstrate that selective overexpression of the stress protein heme oxygenase-1 (ho-1) in astrocytes of novel gfap.hmox1 transgenic mice results in subcortical oxidative stress and mitochondrial damage/autophagy; diminished neuronal reelin content (males); induction of nurr1 and pitx3 with attendant suppression of their targeting mirnas, 145 and 133b; increased tyrosine hydroxylase and α-synuclein expression with downregulation of the targeting mir-7b of the latter; augmented dopamine and serotonin levels in basal ganglia; reduced d1 receptor binding in nucleus accumbens; axodendritic pathology and altered hippocampal cytoarchitectonics; impaired neurovascular coupling; attenuated prepulse inhibition (males); and hyperkinetic behavior. |
2012-10-26 |
2023-08-12 |
mouse |
| Laura Cristina Berumen, Angelina Rodríguez, Ricardo Miledi, Guadalupe García-Alcoce. Serotonin receptors in hippocampus. TheScientificWorldJournal. vol 2012. 2012-10-19. PMID:22629209. |
serotonin receptors in hippocampus. |
2012-10-19 |
2023-08-12 |
Not clear |
| Laura Cristina Berumen, Angelina Rodríguez, Ricardo Miledi, Guadalupe García-Alcoce. Serotonin receptors in hippocampus. TheScientificWorldJournal. vol 2012. 2012-10-19. PMID:22629209. |
serotonin is an ancient molecular signal and a recognized neurotransmitter brainwide distributed with particular presence in hippocampus. |
2012-10-19 |
2023-08-12 |
Not clear |
| Lin Xia, Claudine Deloménie, Indira David, Quentin Rainer, Myriam Marouard, Hervé Delacroix, Denis J David, Alain M Gardier, Jean-Philippe Guillou. Ventral hippocampal molecular pathways and impaired neurogenesis associated with 5-HT₁A and 5-HT₁B receptors disruption in mice. Neuroscience letters. vol 521. issue 1. 2012-10-15. PMID:22622174. |
as ventral hippocampus is a key region in the mediation and genesis of anxiety, we explored the transcriptome changes induced by the genetic inactivation of these two receptors in 5-ht(1a/1b)(-/-) mice. |
2012-10-15 |
2023-08-12 |
mouse |
| Lin Xia, Claudine Deloménie, Indira David, Quentin Rainer, Myriam Marouard, Hervé Delacroix, Denis J David, Alain M Gardier, Jean-Philippe Guillou. Ventral hippocampal molecular pathways and impaired neurogenesis associated with 5-HT₁A and 5-HT₁B receptors disruption in mice. Neuroscience letters. vol 521. issue 1. 2012-10-15. PMID:22622174. |
furthermore, immunohistochemistry experiments studying adult hippocampal neurogenesis in adult 5-ht(1a/1b)(-/-) mice showed a decreased survival, but not proliferation of newborn cells in our model. |
2012-10-15 |
2023-08-12 |
mouse |
| Jeannine Baumgartner, Cornelius M Smuts, Linda Malan, Myrtha Arnold, Benjamin K Yee, Laura E Bianco, Mark V Boekschoten, Michael Müller, Wolfgang Langhans, Richard F Hurrell, Michael B Zimmerman. In male rats with concurrent iron and (n-3) fatty acid deficiency, provision of either iron or (n-3) fatty acids alone alters monoamine metabolism and exacerbates the cognitive deficits associated with combined deficiency. The Journal of nutrition. vol 142. issue 8. 2012-10-10. PMID:22739376. |
dopamine (da) receptor d1 was upregulated in the hippocampus of fe+dha/epa rats (fold-change = 1.25; p < 0.05) and there were significant fe x dha/epa interactions on serotonin (5-ht) in the ob and on the da metabolite dihydroxyphenylacetic acid in the fc and striatum. |
2012-10-10 |
2023-08-12 |
rat |