| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P M Pitychoutis, C Dalla, A C Sideris, P A Tsonis, Z Papadopoulou-Daifot. 5-HT(1A), 5-HT(2A), and 5-HT(2C) receptor mRNA modulation by antidepressant treatment in the chronic mild stress model of depression: sex differences exposed. Neuroscience. vol 210. 2012-09-21. PMID:22441040. |
cms and clomipramine treatment induced sex-differentiated effects on rats' hedonic status and enhanced 5-ht(1a)r mrna expression in the cornu ammonis 1 (ca1) hippocampal region of male rats. |
2012-09-21 |
2023-08-12 |
rat |
| Pedro Melo, Ana Magalhães, Cecília J Alves, Maria Amélia Tavares, Liliana de Sousa, Teresa Summavielle, Pedro Moradas-Ferreir. Methamphetamine mimics the neurochemical profile of aging in rats and impairs recognition memory. Neurotoxicology. vol 33. issue 3. 2012-09-18. PMID:22433442. |
neurochemical analysis indicated similar ma- and age-related impairments in dopamine, serotonin and metabolites in the striatum, prefrontal cortex and hippocampus. |
2012-09-18 |
2023-08-12 |
rat |
| Anne Lesemann, Claudia Reinel, Petra Hühnchen, Maximilian Pilhatsch, Rainer Hellweg, Philipp Klaissle, Christine Winter, Barbara Steine. MPTP-induced hippocampal effects on serotonin, dopamine, neurotrophins, adult neurogenesis and depression-like behavior are partially influenced by fluoxetine in adult mice. Brain research. vol 1457. 2012-09-13. PMID:22520437. |
mptp-induced hippocampal effects on serotonin, dopamine, neurotrophins, adult neurogenesis and depression-like behavior are partially influenced by fluoxetine in adult mice. |
2012-09-13 |
2023-08-12 |
mouse |
| Francis Chaoulof. Neurogenetics of emotional reactivity to stress in animals. Dialogues in clinical neuroscience. vol 4. issue 4. 2012-09-10. PMID:22034202. |
our most recent findings show that the fischer 344 and lew strains differ in protein expression and function of hippocampal and platelet 5-htt; the divergence in protein expression is not due to allelic variations in the gene-coding sequences and leads to marked differences in extracellular 5-ht levels under basal conditions or ssri. |
2012-09-10 |
2023-08-12 |
mouse |
| E Tousson, W Ibrahim, N Arafa, M A Akel. Monoamine concentrations changes in the PTU-induced hypothyroid rat brain and the ameliorating role of folic acid. Human & experimental toxicology. vol 31. issue 3. 2012-09-04. PMID:21478293. |
our results revealed that serotonin and norepinephrine concentrations were significantly decreased in the hypothalamus and cortex, while it significantly increased in the hippocampus of hypothyroid rats when compared with control group. |
2012-09-04 |
2023-08-12 |
rat |
| E Tousson, W Ibrahim, N Arafa, M A Akel. Monoamine concentrations changes in the PTU-induced hypothyroid rat brain and the ameliorating role of folic acid. Human & experimental toxicology. vol 31. issue 3. 2012-09-04. PMID:21478293. |
serotonin and norepinephrine concentrations were decreased in hypothalamus and cortex in co- and post-treated folic acid groups with hypothyroid rats, while the concentration of dopamine were significantly increased in the hypothalamus and hippocampus of the hypothyroid rats and co-treated folic acid group with hypothyroid rats. |
2012-09-04 |
2023-08-12 |
rat |
| Kanji Yoshimoto, Yoshihisa Watanabe, Masaki Tanaka, Minoru Kimur. Serotonin2C receptors in the nucleus accumbens are involved in enhanced alcohol-drinking behavior. The European journal of neuroscience. vol 35. issue 8. 2012-08-27. PMID:22512261. |
in the alcohol-exposed mice, the expression of 5-ht(2c) receptor mrna increased in the acc, caudate nucleus and putamen, dorsal raphe nucleus (drn), hippocampus and lateral hypothalamus, while the protein level of 5-ht(2c) receptor significantly increased in the acc. |
2012-08-27 |
2023-08-12 |
mouse |
| Xiu-qi Bao, Ben Liu, Bing Su. [Effects of Tiaoxin and Zishen prescription on hippocampus neurotransmitters in Alzheimer's disease rats]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 21. issue 1. 2012-08-24. PMID:21166165. |
a method of stereotaxic apparatus was employed to damage the nucleus basalis of meynert, and the effects of tiao-xinzishen prescriptions on neurotransmitters such as ach, 5-ht and ne in hippocampus were observed. |
2012-08-24 |
2023-08-12 |
rat |
| Elena Puerta, Lucia Barros-Miñones, Isabel Hervias, Violeta Gomez-Rodriguez, Lourdes Orejana, Neus Pizarro, Rafael de la Torre, Joaquín Jordán, Norberto Aguirr. Long-lasting neuroprotective effect of sildenafil against 3,4-methylenedioxymethamphetamine- induced 5-hydroxytryptamine deficits in the rat brain. Journal of neuroscience research. vol 90. issue 2. 2012-08-23. PMID:21948520. |
one week later, 5-ht content and 5-ht transporter density were measured in the striatum, frontal cortex, and hippocampus of the rats. |
2012-08-23 |
2023-08-12 |
rat |
| Darakhshan Jabeen Halee. Raphe-Hippocampal Serotonin Neurotransmission In The Sex Related Differences of Adaptation to Stress: Focus on Serotonin-1A Receptor. Current neuropharmacology. vol 9. issue 3. 2012-08-23. PMID:22379463. |
a decrease in the function of 5-hydroxytryptamine (5-ht; serotonin) in the hippocampus and an increased function of the 5-ht-1a receptor in the raphe nucleus coexist in depression. |
2012-08-23 |
2023-08-12 |
Not clear |
| Darakhshan Jabeen Halee. Raphe-Hippocampal Serotonin Neurotransmission In The Sex Related Differences of Adaptation to Stress: Focus on Serotonin-1A Receptor. Current neuropharmacology. vol 9. issue 3. 2012-08-23. PMID:22379463. |
pharmacological and neurochemical data are relevant that facilitation of serotonin neurotransmission via hippocampus due to desensitization of somatodendritic 5-ht1a receptors may lead to adaptation to stress. |
2012-08-23 |
2023-08-12 |
Not clear |
| Lieh-Ching Hsu, Yu-Jen Ko, Hao-Yuan Cheng, Ching-Wen Chang, Yu-Chin Lin, Ying-Hui Cheng, Ming-Tsuen Hsieh, Wen Huang Pen. Antidepressant-Like Activity of the Ethanolic Extract from Uncaria lanosa Wallich var. appendiculata Ridsd in the Forced Swimming Test and in the Tail Suspension Test in Mice. Evidence-based complementary and alternative medicine : eCAM. vol 2012. 2012-08-23. PMID:22567032. |
ul(etoh) increased the levels of 5-ht and 5-hiaa in cortex, striatum, hippocampus, and hypothalamus, the levels of ne and mhpg in cortex and hippocampus, the level of ne in striatum, and the level of dopac in striatum. |
2012-08-23 |
2023-08-12 |
mouse |
| E Soleimannejad, N Naghdi, Sh Khatami, S Semnanian, Y Fathollah. Formalin pain increases the concentration of serotonin and its 5-hydroxyindoleacetic acid metabolite in the CA1 region of hippocampus. Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences. vol 18. issue 1. 2012-08-23. PMID:22615590. |
formalin pain increases the concentration of serotonin and its 5-hydroxyindoleacetic acid metabolite in the ca1 region of hippocampus. |
2012-08-23 |
2023-08-12 |
Not clear |
| Takahiro Masuda, Shin Nakagawa, Shuken Boku, Hiroyuki Nishikawa, Naoki Takamura, Akiko Kato, Takeshi Inoue, Tsukasa Koyam. Noradrenaline increases neural precursor cells derived from adult rat dentate gyrus through β2 receptor. Progress in neuro-psychopharmacology & biological psychiatry. vol 36. issue 1. 2012-08-20. PMID:21914456. |
most antidepressant drugs have ability to increase serotonin (5-ht) and/or noradrenaline (na) in brain, and chronic treatment with antidepressant drugs increases the number of proliferating neural precursor cells and neurogenesis in hippocampus. |
2012-08-20 |
2023-08-12 |
rat |
| Takahiro Masuda, Shin Nakagawa, Shuken Boku, Hiroyuki Nishikawa, Naoki Takamura, Akiko Kato, Takeshi Inoue, Tsukasa Koyam. Noradrenaline increases neural precursor cells derived from adult rat dentate gyrus through β2 receptor. Progress in neuro-psychopharmacology & biological psychiatry. vol 36. issue 1. 2012-08-20. PMID:21914456. |
these results suggest that na might increase the proliferation of early progenitor cells in adult hippocampus via β2-ar directly, but antidepressant drugs and 5-ht do not. |
2012-08-20 |
2023-08-12 |
rat |
| Donatella Marazziti, Stefano Baroni, Andrea Pirone, Gino Giannaccini, Laura Betti, Lara Schmid, Elena Vatteroni, Lionella Palego, Franco Borsini, Fabio Bordi, Ilaria Piano, Claudia Gargini, Maura Castagna, Mario Catena-Dell'osso, Antonio Lucacchin. Distribution of serotonin receptor of type 6 (5-HT₆) in human brain post-mortem. A pharmacology, autoradiography and immunohistochemistry study. Neurochemical research. vol 37. issue 5. 2012-08-20. PMID:22278721. |
the aim of this study was to investigate the distribution of serotonin (5-ht) receptors of type 6 (5-ht(6)) in postmortem human prefrontal cortex, striatum and hippocampus. |
2012-08-20 |
2023-08-12 |
human |
| Donatella Marazziti, Stefano Baroni, Andrea Pirone, Gino Giannaccini, Laura Betti, Lara Schmid, Elena Vatteroni, Lionella Palego, Franco Borsini, Fabio Bordi, Ilaria Piano, Claudia Gargini, Maura Castagna, Mario Catena-Dell'osso, Antonio Lucacchin. Distribution of serotonin receptor of type 6 (5-HT₆) in human brain post-mortem. A pharmacology, autoradiography and immunohistochemistry study. Neurochemical research. vol 37. issue 5. 2012-08-20. PMID:22278721. |
taken together, the present findings showed the presence of a higher density of 5-ht(6) receptors, as labeled by [(125)i]sb-258585, in striatum than in hippocampus and prefrontal cortex, and specifically within the neuronal body. |
2012-08-20 |
2023-08-12 |
human |
| N H K Abdul Aziz, D A Kendall, M-C Pardo. Prenatal exposure to chronic mild stress increases corticosterone levels in the amniotic fluid and induces cognitive deficits in female offspring, improved by treatment with the antidepressant drug amitriptyline. Behavioural brain research. vol 231. issue 1. 2012-08-20. PMID:22409976. |
hippocampal levels of serotonin and its major metabolite were then quantified using high-performance liquid chromatography. |
2012-08-20 |
2023-08-12 |
mouse |
| N H K Abdul Aziz, D A Kendall, M-C Pardo. Prenatal exposure to chronic mild stress increases corticosterone levels in the amniotic fluid and induces cognitive deficits in female offspring, improved by treatment with the antidepressant drug amitriptyline. Behavioural brain research. vol 231. issue 1. 2012-08-20. PMID:22409976. |
amitriptyline elevated hippocampal serotonin levels and attenuated these cognitive deficits. |
2012-08-20 |
2023-08-12 |
mouse |
| Harriët Schellekens, Gerard Clarke, Ian B Jeffery, Timothy G Dinan, John F Crya. Dynamic 5-HT2C receptor editing in a mouse model of obesity. PloS one. vol 7. issue 3. 2012-08-20. PMID:22448217. |
using a leptin-deficient mouse model of obesity (ob/ob), we show increased hypothalamic 5-ht(1a) receptor expression as well as increased hippocampal 5-ht(1a), 5-ht(1b), and 5-ht(6) receptor mrna expression in obese mice compared to lean control mice. |
2012-08-20 |
2023-08-12 |
mouse |