| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Lerer, J Warner, E Friedman, G Vincent, E Gamz. Cortical cholinergic impairment and behavioral deficits produced by kainic acid lesions of rat magnocellular basal forebrain. Behavioral neuroscience. vol 99. issue 4. 1987-09-25. PMID:3843733. |
cortical dopamine levels were unchanged; serotonin levels were unchanged in hippocampus and parietal cortex but decreased in frontal cortex. |
1987-09-25 |
2023-08-11 |
human |
| M Ohno, T Yamamoto, S Uek. Clonidine attenuates wet-dog shaking induced by hippocampal stimulation in rats. European journal of pharmacology. vol 137. issue 2-3. 1987-09-24. PMID:3609139. |
although clonidine has been reported to inhibit the activity not only of noradrenergic but also of serotonergic neurons, a 5-hydroxytryptamine (5-ht) antagonist, cinanserin at doses up to 32 mg/kg had no significant effect on hippocampal stimulation-induced wds. |
1987-09-24 |
2023-08-11 |
rat |
| G Lombardi, O Gandolfi, R Dall'Olio, D E Pellegrini-Giampietro, M Beni, V Carla, A Consolazione, F Moron. Lesioning and recovery of the serotoninergic projections to the hippocampus. Brain research. vol 411. issue 2. 1987-08-28. PMID:2440519. |
the time course of the changes of the hippocampal 5-hydroxytryptamine (5-ht) system after a lesion of the dorsal afferents to this brain area was studied by measuring the content of 5-ht and of 5-hydroxyindoleacetic acid (5-hiaa) in the dorsal, medial and ventral hippocampus. |
1987-08-28 |
2023-08-11 |
Not clear |
| G Lombardi, O Gandolfi, R Dall'Olio, D E Pellegrini-Giampietro, M Beni, V Carla, A Consolazione, F Moron. Lesioning and recovery of the serotoninergic projections to the hippocampus. Brain research. vol 411. issue 2. 1987-08-28. PMID:2440519. |
the contents of 5-ht and of 5-hiaa are higher in the ventral than in the dorsal hippocampus. |
1987-08-28 |
2023-08-11 |
Not clear |
| G Lombardi, O Gandolfi, R Dall'Olio, D E Pellegrini-Giampietro, M Beni, V Carla, A Consolazione, F Moron. Lesioning and recovery of the serotoninergic projections to the hippocampus. Brain research. vol 411. issue 2. 1987-08-28. PMID:2440519. |
seven days after the lesion the 5-ht content decreases by 78% in the dorsal and by 50% in the ventral hippocampus. |
1987-08-28 |
2023-08-11 |
Not clear |
| G Lombardi, O Gandolfi, R Dall'Olio, D E Pellegrini-Giampietro, M Beni, V Carla, A Consolazione, F Moron. Lesioning and recovery of the serotoninergic projections to the hippocampus. Brain research. vol 411. issue 2. 1987-08-28. PMID:2440519. |
these results suggest that important changes occur in the 5-ht innervation of the hippocampus after a mechanical lesion: among these we showed a slow collateral sprouting, an increased utilization of the amine and a supersensitivity of 5-ht receptors. |
1987-08-28 |
2023-08-11 |
Not clear |
| T D Steele, D E Nichols, G K Yi. Stereochemical effects of 3,4-methylenedioxymethamphetamine (MDMA) and related amphetamine derivatives on inhibition of uptake of [3H]monoamines into synaptosomes from different regions of rat brain. Biochemical pharmacology. vol 36. issue 14. 1987-08-19. PMID:2886126. |
both stereoisomers of mdma, mda and mbdb were potent inhibitors of [3h]serotonin uptake into hippocampal synaptosomes, but only s-(+)-amphetamine produced an appreciable inhibition of [3h]serotonin uptake. |
1987-08-19 |
2023-08-11 |
rat |
| F C Zhou, S Auerbach, E Azmiti. Denervation of serotonergic fibers in the hippocampus induced a trophic factor which enhances the maturation of transplanted serotonergic neurons but not norepinephrine neurons. Journal of neuroscience research. vol 17. issue 3. 1987-08-11. PMID:3037093. |
the trophic effects of specific denervation on the growth and survival of fetal serotonergic (5-ht) or norepinephrinergic (ne) neurons grafted into the hippocampus were assessed by means of two transplantation paradigms. |
1987-08-11 |
2023-08-11 |
Not clear |
| F C Zhou, S Auerbach, E Azmiti. Denervation of serotonergic fibers in the hippocampus induced a trophic factor which enhances the maturation of transplanted serotonergic neurons but not norepinephrine neurons. Journal of neuroscience research. vol 17. issue 3. 1987-08-11. PMID:3037093. |
in the first, fetal raphe cells (containing 5-ht neurons) were transplanted into the control hippocampus. |
1987-08-11 |
2023-08-11 |
Not clear |
| F C Zhou, S Auerbach, E Azmiti. Denervation of serotonergic fibers in the hippocampus induced a trophic factor which enhances the maturation of transplanted serotonergic neurons but not norepinephrine neurons. Journal of neuroscience research. vol 17. issue 3. 1987-08-11. PMID:3037093. |
in the second, the transplantation was performed 2 weeks after the specific removal of 5-ht afferents to the hippocampus with 5,7-dihydroxytryptamine (5,7-dht). |
1987-08-11 |
2023-08-11 |
Not clear |
| F C Zhou, S Auerbach, E Azmiti. Denervation of serotonergic fibers in the hippocampus induced a trophic factor which enhances the maturation of transplanted serotonergic neurons but not norepinephrine neurons. Journal of neuroscience research. vol 17. issue 3. 1987-08-11. PMID:3037093. |
however, transplanted raphe neurons had 400% more 5-ht synaptosomal high-affinity uptake and 380% higher content of 5-ht in the hippocampus with prior 5,7-dht lesion than in control hippocampus. |
1987-08-11 |
2023-08-11 |
Not clear |
| F C Zhou, S Auerbach, E Azmiti. Denervation of serotonergic fibers in the hippocampus induced a trophic factor which enhances the maturation of transplanted serotonergic neurons but not norepinephrine neurons. Journal of neuroscience research. vol 17. issue 3. 1987-08-11. PMID:3037093. |
furthermore, immunocytochemistry showed that the transplanted 5-ht neurons had denser processes and varicosities in the hippocampus with lesion than in control hippocampus. |
1987-08-11 |
2023-08-11 |
Not clear |
| F C Zhou, S Auerbach, E Azmiti. Denervation of serotonergic fibers in the hippocampus induced a trophic factor which enhances the maturation of transplanted serotonergic neurons but not norepinephrine neurons. Journal of neuroscience research. vol 17. issue 3. 1987-08-11. PMID:3037093. |
a greater 5-ht level could be achieved if transplanted neurons in the control hippocampus were treated with the supernatant extracted from the hippocampus with 5,7-dht lesion. |
1987-08-11 |
2023-08-11 |
Not clear |
| F C Zhou, S Auerbach, E Azmiti. Denervation of serotonergic fibers in the hippocampus induced a trophic factor which enhances the maturation of transplanted serotonergic neurons but not norepinephrine neurons. Journal of neuroscience research. vol 17. issue 3. 1987-08-11. PMID:3037093. |
in contrast, the ne level of the implanted fetal locus ceruleus (containing ne neurons) was not significantly higher in the 5-ht denervated hippocampus than in control hippocampus a month after transplantation. |
1987-08-11 |
2023-08-11 |
Not clear |
| F C Zhou, S Auerbach, E Azmiti. Denervation of serotonergic fibers in the hippocampus induced a trophic factor which enhances the maturation of transplanted serotonergic neurons but not norepinephrine neurons. Journal of neuroscience research. vol 17. issue 3. 1987-08-11. PMID:3037093. |
these results suggest that 5-ht denervation in the hippocampus induces a trophic substance which promotes the maturation rather than survival of 5-ht neurons but not ne neurons. |
1987-08-11 |
2023-08-11 |
Not clear |
| A Ennaceur, J Delacou. Effect of combined or separate administration of piracetam and choline on learning and memory in the rat. Psychopharmacology. vol 92. issue 1. 1987-08-04. PMID:3110830. |
the combined or separate administration of p1 and c1 on na, da, dopac, 5-ht, 5-hiaa levels, cat activity and choline uptake were measured in frontal cortex and hippocampus: the only significant effect was a 5-ht increase in the hippocampus of rats treated with c1. |
1987-08-04 |
2023-08-11 |
rat |
| A Colino, J V Halliwel. Differential modulation of three separate K-conductances in hippocampal CA1 neurons by serotonin. Nature. vol 328. issue 6125. 1987-07-31. PMID:3600775. |
serotonin applied to hippocampal neurons to mimic the action of endogenous transmitter often produces complex and variable responses (see for example ref. |
1987-07-31 |
2023-08-11 |
rat |
| A Colino, J V Halliwel. Differential modulation of three separate K-conductances in hippocampal CA1 neurons by serotonin. Nature. vol 328. issue 6125. 1987-07-31. PMID:3600775. |
using voltage-clamp methods and new ligands that are selective for subtypes of serotonin receptors, we have been able to clarify the mechanism of serotonin action on ca1 cells in rat hippocampal slices. |
1987-07-31 |
2023-08-11 |
rat |
| A M Copland, D J Balfou. Spontaneous activity and brain 5-hydroxyindole levels measured in rats tested in two designs of elevated X-maze. Life sciences. vol 41. issue 1. 1987-07-29. PMID:2439864. |
chronic exposure to the open maze caused significant increases (p less than 0.01) in the concentrations of 5-hydroxytryptamine (5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) in hippocampus, hypothalamus and cerebral cortex when compared with unstressed control rats. |
1987-07-29 |
2023-08-11 |
rat |
| A M Copland, D J Balfou. Spontaneous activity and brain 5-hydroxyindole levels measured in rats tested in two designs of elevated X-maze. Life sciences. vol 41. issue 1. 1987-07-29. PMID:2439864. |
when compared with the data for the rats tested repeatedly in the enclosed maze, chronic exposure to the open maze increased the 5-ht concentrations in hypothalamus (p less than 0.05) and cerebral cortex (p less than 0.01) and the 5-hiaa concentrations in hypothalamus (p less than 0.01) and hippocampus (p less than 0.01). |
1987-07-29 |
2023-08-11 |
rat |