| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D L Commins, K J Axt, G Vosmer, L S Seide. 5,6-Dihydroxytryptamine, a serotonergic neurotoxin, is formed endogenously in the rat brain. Brain research. vol 403. issue 1. 1987-05-20. PMID:2435369. |
the 5,6-dht was detected by reverse-phase high-performance liquid chromatography with electrochemical detection in tissue samples taken 0.5-4 h after ma administration; the highest levels of 5,6-dht (0.032 ng/mg wet tissue) were detected at 1 h. following administration of ma, 5-ht was also depleted in the neocortex, but 5,6-dht was not detected as frequently in this brain region as in the hippocampus. |
1987-05-20 |
2023-08-11 |
rat |
| D L Commins, K J Axt, G Vosmer, L S Seide. 5,6-Dihydroxytryptamine, a serotonergic neurotoxin, is formed endogenously in the rat brain. Brain research. vol 403. issue 1. 1987-05-20. PMID:2435369. |
comparisons were made between the long-term hippocampal 5-ht depletions seen either after an injection of ma or after intraventricular 5,6-dht infusions and the levels of 5,6-dht measured in the hippocampus shortly after each treatment. |
1987-05-20 |
2023-08-11 |
rat |
| J Lewis, V Westerberg, M E Corcora. Monoaminergic correlates of kindling. Brain research. vol 403. issue 2. 1987-05-20. PMID:3828819. |
four weeks after kindling we found significant depletions of na in the stimulated amygdala and ipsilateral hypothalamus, a significant depletion of 5-ht in the ipsilateral hippocampus, and no significant changes in da. |
1987-05-20 |
2023-08-11 |
rat |
| E Edwards, P M Whitaker-Azmiti. Selective beta-antagonists are equally and highly potent at 5-HT sites in the rat hippocampus. Neuropharmacology. vol 26. issue 1. 1987-05-07. PMID:2882439. |
selective beta-antagonists are equally and highly potent at 5-ht sites in the rat hippocampus. |
1987-05-07 |
2023-08-11 |
rat |
| E Edwards, P M Whitaker-Azmiti. Selective beta-antagonists are equally and highly potent at 5-HT sites in the rat hippocampus. Neuropharmacology. vol 26. issue 1. 1987-05-07. PMID:2882439. |
serotonin (5-hydroxytryptamine, 5-ht) and various tryptamine-related drugs were equi-potent to known beta-antagonists in competition experiments of 125iodo-cyanopindolol binding in the rat hippocampus. |
1987-05-07 |
2023-08-11 |
rat |
| E Edwards, P M Whitaker-Azmiti. Selective beta-antagonists are equally and highly potent at 5-HT sites in the rat hippocampus. Neuropharmacology. vol 26. issue 1. 1987-05-07. PMID:2882439. |
saturation experiments demonstrated that in the rat hippocampus, a subpopulation of serotonin recognition sites comprised 50% of 125i-cyp binding. |
1987-05-07 |
2023-08-11 |
rat |
| M T Hsieh, H C Chen, H C Kao, T Shibuy. Suanzaorentang, and anxiolytic Chinese medicine, affects the central adrenergic and serotonergic systems in rats. Proceedings of the National Science Council, Republic of China. Part B, Life sciences. vol 10. issue 4. 1987-04-29. PMID:2882534. |
in this study, we found that 5-hydroxytryptophan (5-htp) induced decrease in locomotor activity was significantly antagonized by suanzaorentang, p-chlorophenylalanine (p-cpa) induced increase in locomotor activity was significantly inhibited by suanzaorentang, suanzaorentang had no significant effects on baclofen, muscimol, aminooxyacetic acid (aoaa) and thiosemicarbazide induced changes in locomotor activity, suanzaorentang significantly decreased vanillylmandelic acid (vma) in striatum and hippocampus, homovanillic acid (hva) in hippocampus and 5-hydroxyindol acetic acid (5-hiaa) in striatum and hypothalamus, suanzaorentang significantly reversed the alpha-methyltyrosine (alpha-mt) produced decrease in da concentrations in striatum and hippocampus, and (6) suanzaorentang significantly reversed the p-cpa produced decrease in 5-ht concentrations on amygdala. |
1987-04-29 |
2023-08-11 |
rat |
| J A Scott, F T Crew. Down-regulation of serotonin2, but not of beta-adrenergic receptors during chronic treatment with amitriptyline is independent of stimulation of serotonin2 and beta-adrenergic receptors. Neuropharmacology. vol 25. issue 12. 1987-04-29. PMID:3031528. |
in addition, the depletion of central stores of norepinephrine and serotonin by a 4-day treatment with reserpine (5 mg/kg per day) increased binding to beta receptors in the cerebral cortex and hippocampus, but did not affect binding to 5-ht2 receptors in either region. |
1987-04-29 |
2023-08-11 |
Not clear |
| D H Versteeg, W J Florij. Phorbol 12,13-dibutyrate enhances electrically stimulated neuromessenger release from rat dorsal hippocampal slices in vitro. Life sciences. vol 40. issue 13. 1987-04-27. PMID:2882398. |
the protein kinase c activator 4 beta-phorbol 12,13-dibutyrate (pdb) enhanced the electrically stimulated release of radiolabelled noradrenaline (na), acetylcholine (ach) and 5-hydroxytryptamine (5-ht) from dorsal hippocampal slices of the rat in vitro in a concentration-dependent manner. |
1987-04-27 |
2023-08-11 |
rat |
| D H Versteeg, W J Florij. Phorbol 12,13-dibutyrate enhances electrically stimulated neuromessenger release from rat dorsal hippocampal slices in vitro. Life sciences. vol 40. issue 13. 1987-04-27. PMID:2882398. |
taken together, the present data suggest that the diacylglycerol/protein kinase c pathway is involved in the stimulus-evoked release of na, ach and 5-ht from dorsal hippocampal nerve terminals. |
1987-04-27 |
2023-08-11 |
rat |
| F Besnard, E Kempf, G Fuhrmann, J Kempf, A Ebe. Influence of mouse genotype on responses of central biogenic amines to alcohol intoxication and aging. Alcohol (Fayetteville, N.Y.). vol 3. issue 6. 1987-04-22. PMID:3814344. |
dopamine and serotonin responses to various periods of alcohol treatment have been followed in striatum and hippocampus of two inbred strains of mice and related to the effect of aging. |
1987-04-22 |
2023-08-11 |
mouse |
| G Maura, E Roccatagliata, M Raiter. Serotonin autoreceptor in rat hippocampus: pharmacological characterization as a subtype of the 5-HT1 receptor. Naunyn-Schmiedeberg's archives of pharmacology. vol 334. issue 4. 1987-04-20. PMID:3821924. |
serotonin autoreceptor in rat hippocampus: pharmacological characterization as a subtype of the 5-ht1 receptor. |
1987-04-20 |
2023-08-11 |
rat |
| G Maura, E Roccatagliata, M Raiter. Serotonin autoreceptor in rat hippocampus: pharmacological characterization as a subtype of the 5-HT1 receptor. Naunyn-Schmiedeberg's archives of pharmacology. vol 334. issue 4. 1987-04-20. PMID:3821924. |
the 5-hydroxytryptamine (5-ht) autoreceptors mediating inhibition of [3h]5-ht release in rat hippocampus have been characterized pharmacologically in terms of 5-ht receptor subtype by using superfused synaptosomes depolarized with 15 mm kcl. |
1987-04-20 |
2023-08-11 |
rat |
| G Maura, E Roccatagliata, M Raiter. Serotonin autoreceptor in rat hippocampus: pharmacological characterization as a subtype of the 5-HT1 receptor. Naunyn-Schmiedeberg's archives of pharmacology. vol 334. issue 4. 1987-04-20. PMID:3821924. |
in conclusion, 5-ht nerve terminals of rat hippocampus possess autoreceptors which appear to belong to the 5-ht1b subtype. |
1987-04-20 |
2023-08-11 |
rat |
| b' G Ebinger, M Bruyland, J J Martin, P Herregodts, P Cras, Y Michotte, L Gomm\\xc3\\xa. Distribution of biogenic amines and their catabolites in brains from patients with Alzheimer\'s disease. Journal of the neurological sciences. vol 77. issue 2-3. 1987-04-08. PMID:3819769.' |
in the patient suffering from the less severe dementia, there was a severe reduction of the serotonin concentration in all examined neocortical areas and its concentration was even below the detection limit in the nucleus amygdalis, hippocampus, caudate nucleus, putamen, globus pallidus and substantia nigra. |
1987-04-08 |
2023-08-11 |
Not clear |
| M P Johnson, A J Hoffman, D E Nichol. Effects of the enantiomers of MDA, MDMA and related analogues on [3H]serotonin and [3H]dopamine release from superfused rat brain slices. European journal of pharmacology. vol 132. issue 2-3. 1987-04-07. PMID:2880735. |
the primary amines 3,4-methylenedioxyamphetamine (mda), and 1-(1,3-benzodioxol-5-yl)-2-butanamine (bdb) were measured for efficacy in release of [3h]serotonin (5-ht) from rat hippocampal slices, and release of [3h]dopamine (da) from rat caudate nucleus slices. |
1987-04-07 |
2023-08-11 |
human |
| S Benkirane, S Arbilla, S Z Lange. Newly synthesized noradrenaline mediates the alpha 2-adrenoceptor inhibition of [3H]5-hydroxytryptamine release induced by beta-phenylethylamine in rat hippocampal slices. European journal of pharmacology. vol 131. issue 2-3. 1987-04-07. PMID:3028829. |
newly synthesized noradrenaline mediates the alpha 2-adrenoceptor inhibition of [3h]5-hydroxytryptamine release induced by beta-phenylethylamine in rat hippocampal slices. |
1987-04-07 |
2023-08-11 |
rat |
| S Benkirane, S Arbilla, S Z Lange. Newly synthesized noradrenaline mediates the alpha 2-adrenoceptor inhibition of [3H]5-hydroxytryptamine release induced by beta-phenylethylamine in rat hippocampal slices. European journal of pharmacology. vol 131. issue 2-3. 1987-04-07. PMID:3028829. |
in slices of the rat hippocampus, alpha 2-adrenoceptors located presynaptically on serotonergic nerve terminals modulate the electrically evoked calcium-dependent release of [3h]serotonin [( 3h]5ht). |
1987-04-07 |
2023-08-11 |
rat |
| S Benkirane, S Arbilla, S Z Lange. Newly synthesized noradrenaline mediates the alpha 2-adrenoceptor inhibition of [3H]5-hydroxytryptamine release induced by beta-phenylethylamine in rat hippocampal slices. European journal of pharmacology. vol 131. issue 2-3. 1987-04-07. PMID:3028829. |
this inhibitory effect appears to be mediated exclusively through the release of newly synthesized noradrenaline, and does not involve the direct activation by beta-pea of the inhibitory 5ht autoreceptors which modulate [3h]5ht release in the rat hippocampus. |
1987-04-07 |
2023-08-11 |
rat |
| G Gaál, P E Potter, I Hanin, I Kakucska, E S Viz. Effects of intracerebroventricular AF64A administration on cholinergic, serotoninergic and catecholaminergic circuitry in rat dorsal hippocampus. Neuroscience. vol 19. issue 4. 1987-04-06. PMID:2881229. |
these findings are consistent with the neurochemical data obtained in parallel experiments with the morphological study in which it was found that acetylcholine content of the hippocampus was reduced by 73.4% 7 days after ethylcholine mustard aziridinium ion treatment, while dopamine, noradrenaline and serotonin levels were unaffected. |
1987-04-06 |
2023-08-11 |
rat |