| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C P Mauriz. Dementia--the failure of hippocampal plasticity and dreams. Is there a preventative role for melatonin? Medical hypotheses. vol 24. issue 1. 1987-12-08. PMID:3312972. |
when compared to age-matched controls, demented patients have decreased hippocampal norepinephrine and serotonin, increased hippocampal monoamine oxidase, and decreased rem sleep. |
1987-12-08 |
2023-08-11 |
Not clear |
| E Hansson, P Simonsson, C Allin. 5-Hydroxytryptamine stimulates the formation of inositol phosphate in astrocytes from different regions of the brain. Neuropharmacology. vol 26. issue 9. 1987-12-07. PMID:2823165. |
5-hydroxytryptamine (5-ht) stimulated the turnover of phosphoinositide in primary cultures of astroglia from the cerebral cortex, striatum, hippocampus and brain stem. |
1987-12-07 |
2023-08-11 |
Not clear |
| T J Feuerstein, C Allgaier, G Herttin. Possible involvement of protein kinase C (PKC) in the regulation of electrically evoked serotonin (5-HT) release from rabbit hippocampal slices. European journal of pharmacology. vol 139. issue 3. 1987-11-27. PMID:3666005. |
possible involvement of protein kinase c (pkc) in the regulation of electrically evoked serotonin (5-ht) release from rabbit hippocampal slices. |
1987-11-27 |
2023-08-11 |
rabbit |
| T J Feuerstein, C Allgaier, G Herttin. Possible involvement of protein kinase C (PKC) in the regulation of electrically evoked serotonin (5-HT) release from rabbit hippocampal slices. European journal of pharmacology. vol 139. issue 3. 1987-11-27. PMID:3666005. |
protein kinase c (pkc)-activating phorbol esters enhanced the electrically evoked 5-ht release from rabbit hippocampal slices preincubated with [3h]5-ht. |
1987-11-27 |
2023-08-11 |
rabbit |
| E H Lee, H H Lin, H M Yi. Differential influences of different stressors upon midbrain raphe neurons in rats. Neuroscience letters. vol 80. issue 1. 1987-11-18. PMID:2443877. |
results indicate that shock-induced fighting experience preferentially decreased serotonin (5-ht) levels in the dorsal raphe and striatum, while air puff stimulation selectively lowered 5-ht and 5-hydroxyindoleacetic acid (5-hiaa) contents in the median raphe and hippocampus. |
1987-11-18 |
2023-08-11 |
rat |
| T J Feuerstein, A Lupp, G Herttin. The serotonin (5-HT) autoreceptor in the hippocampus of the rabbit: role of 5-HT biophase concentration. Neuropharmacology. vol 26. issue 8. 1987-11-18. PMID:2958718. |
the serotonin (5-ht) autoreceptor in the hippocampus of the rabbit: role of 5-ht biophase concentration. |
1987-11-18 |
2023-08-11 |
rat |
| T J Feuerstein, A Lupp, G Herttin. The serotonin (5-HT) autoreceptor in the hippocampus of the rabbit: role of 5-HT biophase concentration. Neuropharmacology. vol 26. issue 8. 1987-11-18. PMID:2958718. |
slices of hippocampus from the rabbit were preincubated with [3h]5-ht), then superfused continuously and twice stimulated electrically. |
1987-11-18 |
2023-08-11 |
rat |
| D Graham, L Tahraoui, S Z Lange. Effect of chronic treatment with selective monoamine oxidase inhibitors and specific 5-hydroxytryptamine uptake inhibitors on [3H]paroxetine binding to cerebral cortical membranes of the rat. Neuropharmacology. vol 26. issue 8. 1987-11-18. PMID:2958720. |
[3h]paroxetine is a highly selective ligand for the 5-hydroxytryptamine transporter complex and the specific binding of this ligand to membrane fractions from cerebral cortex or hippocampus was studied in rats treated with specific inhibitors of the uptake of 5-hydroxytryptamine and monoamine oxidase inhibitors. |
1987-11-18 |
2023-08-11 |
rat |
| G Battaglia, S Y Yeh, E O'Hearn, M E Molliver, M J Kuhar, E B De Souz. 3,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetine-labeled serotonin uptake sites. The Journal of pharmacology and experimental therapeutics. vol 242. issue 3. 1987-11-05. PMID:2443644. |
marked reductions (30-60%) in the concentration of 5-hydroxyindoleacetic acid were observed in cerebral cortex, hippocampus, striatum, hypothalamus and midbrain at 2 weeks after a 4-day treatment regimen of mdma or mda; less consistent reductions in serotonin (5-ht) content were observed in these brain regions. |
1987-11-05 |
2023-08-11 |
rat |
| A M Copland, D J Balfou. The effects of diazepam on brain 5-HT and 5-HIAA in stressed and unstressed rats. Pharmacology, biochemistry, and behavior. vol 27. issue 4. 1987-10-29. PMID:2443932. |
acute diazepam (25 mg/kg) increased (p less than 0.05) hippocampal 5-hydroxyindoleacetic acid; its withdrawal from unstressed rats after 40 days reduced (p less than 0.01) hypothalamic 5-hydroxytryptamine. |
1987-10-29 |
2023-08-11 |
rat |
| H Hörtnagl, P E Potter, I Hani. Effect of cholinergic deficit induced by ethylcholine aziridinium on serotonergic parameters in rat brain. Neuroscience. vol 22. issue 1. 1987-10-22. PMID:2442662. |
as with acetylcholine, the decrease in serotonin content was most pronounced in the hippocampus, ranged from 19.4 +/- 2.9% to 53.4 +/- 4.1%, and even persisted at 28 days after injection of 3 and 5 nmoles of the toxin/ventricle, although serotonin levels returned towards normal at that time point after injection of 1 or 2 nmoles of the toxin/ventricle. |
1987-10-22 |
2023-08-11 |
rat |
| A G Silina, A G Sverdlov. [Effect of super-high doses of gamma-radiation on the level and metabolism of serotonin in the rat brain]. Radiobiologiia. vol 27. issue 4. 1987-10-22. PMID:2442793. |
as early as 60 mi after gamma-irradiation of wistar rats with a dose of 150 gy the content of serotonin and 5-hydroxyindoleacetic acid decreases in the midbrain, hippocampus, and cerebral hemisphere cortex. |
1987-10-22 |
2023-08-11 |
rat |
| R Andrade, R A Nicol. Novel anxiolytics discriminate between postsynaptic serotonin receptors mediating different physiological responses on single neurons of the rat hippocampus. Naunyn-Schmiedeberg's archives of pharmacology. vol 336. issue 1. 1987-10-22. PMID:2888027. |
novel anxiolytics discriminate between postsynaptic serotonin receptors mediating different physiological responses on single neurons of the rat hippocampus. |
1987-10-22 |
2023-08-11 |
rat |
| R Andrade, R A Nicol. Novel anxiolytics discriminate between postsynaptic serotonin receptors mediating different physiological responses on single neurons of the rat hippocampus. Naunyn-Schmiedeberg's archives of pharmacology. vol 336. issue 1. 1987-10-22. PMID:2888027. |
since the buspirone induced hyperpolarization was also accompanied by a surmountable antagonism of 5-ht responses, these results indicate that buspirone behaves as a partial agonist at a subpopulation of 5-ht receptors in the ca1 region of the hippocampus. |
1987-10-22 |
2023-08-11 |
rat |
| D G Morga. The dopamine and serotonin systems during aging in human and rodent brain. A brief review. Progress in neuro-psychopharmacology & biological psychiatry. vol 11. issue 2-3. 1987-10-15. PMID:2819950. |
the density of s-2 serotonin receptors declines 20-50% with age in human frontal cortex and hippocampus, and by 30% in mouse cortex. |
1987-10-15 |
2023-08-11 |
mouse |
| G P Reynolds, S J Pearso. Decreased glutamic acid and increased 5-hydroxytryptamine in Huntington's disease brain. Neuroscience letters. vol 78. issue 2. 1987-09-30. PMID:2442679. |
5-ht and 5-hiaa were significantly increased in all areas except the hippocampus. |
1987-09-30 |
2023-08-11 |
human |
| G Maura, M Ulivi, M Raiter. (-)-Propranolol and (+/-)-cyanopindolol are mixed agonists-antagonists at serotonin autoreceptors in the hippocampus of the rat brain. Neuropharmacology. vol 26. issue 7A. 1987-09-30. PMID:3627379. |
(-)-propranolol and (+/-)-cyanopindolol are mixed agonists-antagonists at serotonin autoreceptors in the hippocampus of the rat brain. |
1987-09-30 |
2023-08-11 |
rat |
| G Maura, M Ulivi, M Raiter. (-)-Propranolol and (+/-)-cyanopindolol are mixed agonists-antagonists at serotonin autoreceptors in the hippocampus of the rat brain. Neuropharmacology. vol 26. issue 7A. 1987-09-30. PMID:3627379. |
the effects of (-)-propranolol, (+)-propranolol and (+/-)-cyanopindolol on the release of [3h]5-hydroxytryptamine [( 3h]5-ht) were investigated in synaptosomes from the hippocampus of the rat, depolarized in superfusion with 15 mm kcl. |
1987-09-30 |
2023-08-11 |
rat |
| D J Mokler, S E Robinson, J A Rosecran. (+/-)3,4-Methylenedioxymethamphetamine (MDMA) produces long-term reductions in brain 5-hydroxytryptamine in rats. European journal of pharmacology. vol 138. issue 2. 1987-09-25. PMID:2887440. |
mdma produced significant depletions of 5-ht and its metabolite 5-hiaa in the hippocampus and the frontal cortex. |
1987-09-25 |
2023-08-11 |
rat |
| D J Mokler, S E Robinson, J A Rosecran. (+/-)3,4-Methylenedioxymethamphetamine (MDMA) produces long-term reductions in brain 5-hydroxytryptamine in rats. European journal of pharmacology. vol 138. issue 2. 1987-09-25. PMID:2887440. |
5-ht was depleted to 30% of control value in the hippocampus following a single dose. |
1987-09-25 |
2023-08-11 |
rat |