| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Shenker, S Maayani, H Weinstein, J P Gree. Pharmacological characterization of two 5-hydroxytryptamine receptors coupled to adenylate cyclase in guinea pig hippocampal membranes. Molecular pharmacology. vol 31. issue 4. 1987-05-28. PMID:2952874. |
two 5-hydroxytryptamine (5-ht) receptors mediate stimulation of adenylate cyclase activity in membranes of adult guinea pig hippocampus. |
1987-05-28 |
2023-08-11 |
rat |
| A Shenker, S Maayani, H Weinstein, J P Gree. Pharmacological characterization of two 5-hydroxytryptamine receptors coupled to adenylate cyclase in guinea pig hippocampal membranes. Molecular pharmacology. vol 31. issue 4. 1987-05-28. PMID:2952874. |
rh and rl may also mediate stimulation of adenylate cyclase activity by 5-ht in hippocampal membranes of adult rat. |
1987-05-28 |
2023-08-11 |
rat |
| I Hotta, S Yamawaki, T Segaw. Long-term lithium treatment causes serotonin receptor down-regulation via serotonergic presynapses in rat brain. Neuropsychobiology. vol 16. issue 1. 1987-05-27. PMID:3494960. |
the effects of lithium treatment on serotonin (5-ht) receptors in rat frontal cortex and hippocampus were investigated. |
1987-05-27 |
2023-08-11 |
rat |
| I Hotta, S Yamawaki, T Segaw. Long-term lithium treatment causes serotonin receptor down-regulation via serotonergic presynapses in rat brain. Neuropsychobiology. vol 16. issue 1. 1987-05-27. PMID:3494960. |
the turnover of 5-ht in either frontal cortex or hippocampus was facilitated by lithium, and co-administered methiothepin enhanced this facilitation. |
1987-05-27 |
2023-08-11 |
rat |
| C Eva, M Fabrazzo, E Cost. Changes of cholinergic, noradrenergic and serotonergic synaptic transmission indices elicited by ethylcholine aziridinium ion (AF64A) infused intraventricularly. The Journal of pharmacology and experimental therapeutics. vol 241. issue 1. 1987-05-22. PMID:2437288. |
this af64a treatment also causes a long-lasting decrease of hippocampal norepinephrine and serotonin (5-ht) content. |
1987-05-22 |
2023-08-11 |
rat |
| C Eva, M Fabrazzo, E Cost. Changes of cholinergic, noradrenergic and serotonergic synaptic transmission indices elicited by ethylcholine aziridinium ion (AF64A) infused intraventricularly. The Journal of pharmacology and experimental therapeutics. vol 241. issue 1. 1987-05-22. PMID:2437288. |
even a smaller dose of af64a (1.5 nmol/side) reduces the hippocampal 5-ht content. |
1987-05-22 |
2023-08-11 |
rat |
| C Eva, M Fabrazzo, E Cost. Changes of cholinergic, noradrenergic and serotonergic synaptic transmission indices elicited by ethylcholine aziridinium ion (AF64A) infused intraventricularly. The Journal of pharmacology and experimental therapeutics. vol 241. issue 1. 1987-05-22. PMID:2437288. |
in contrast the decrease of hippocampal 5-ht concentration elicited by af64a fails to change the 5-ht receptor indices that were measured. |
1987-05-22 |
2023-08-11 |
rat |
| D L Commins, G Vosmer, R M Virus, W L Woolverton, C R Schuster, L S Seide. Biochemical and histological evidence that methylenedioxymethylamphetamine (MDMA) is toxic to neurons in the rat brain. The Journal of pharmacology and experimental therapeutics. vol 241. issue 1. 1987-05-22. PMID:2883295. |
norepinephrine, dopamine and serotonin (5-ht) levels were assayed in the hippocampus, hypothalamus, striatum and neocortex. |
1987-05-22 |
2023-08-11 |
rat |
| D L Commins, K J Axt, G Vosmer, L S Seide. 5,6-Dihydroxytryptamine, a serotonergic neurotoxin, is formed endogenously in the rat brain. Brain research. vol 403. issue 1. 1987-05-20. PMID:2435369. |
the 5,6-dht was detected by reverse-phase high-performance liquid chromatography with electrochemical detection in tissue samples taken 0.5-4 h after ma administration; the highest levels of 5,6-dht (0.032 ng/mg wet tissue) were detected at 1 h. following administration of ma, 5-ht was also depleted in the neocortex, but 5,6-dht was not detected as frequently in this brain region as in the hippocampus. |
1987-05-20 |
2023-08-11 |
rat |
| D L Commins, K J Axt, G Vosmer, L S Seide. 5,6-Dihydroxytryptamine, a serotonergic neurotoxin, is formed endogenously in the rat brain. Brain research. vol 403. issue 1. 1987-05-20. PMID:2435369. |
comparisons were made between the long-term hippocampal 5-ht depletions seen either after an injection of ma or after intraventricular 5,6-dht infusions and the levels of 5,6-dht measured in the hippocampus shortly after each treatment. |
1987-05-20 |
2023-08-11 |
rat |
| J Lewis, V Westerberg, M E Corcora. Monoaminergic correlates of kindling. Brain research. vol 403. issue 2. 1987-05-20. PMID:3828819. |
four weeks after kindling we found significant depletions of na in the stimulated amygdala and ipsilateral hypothalamus, a significant depletion of 5-ht in the ipsilateral hippocampus, and no significant changes in da. |
1987-05-20 |
2023-08-11 |
rat |
| E Edwards, P M Whitaker-Azmiti. Selective beta-antagonists are equally and highly potent at 5-HT sites in the rat hippocampus. Neuropharmacology. vol 26. issue 1. 1987-05-07. PMID:2882439. |
selective beta-antagonists are equally and highly potent at 5-ht sites in the rat hippocampus. |
1987-05-07 |
2023-08-11 |
rat |
| E Edwards, P M Whitaker-Azmiti. Selective beta-antagonists are equally and highly potent at 5-HT sites in the rat hippocampus. Neuropharmacology. vol 26. issue 1. 1987-05-07. PMID:2882439. |
serotonin (5-hydroxytryptamine, 5-ht) and various tryptamine-related drugs were equi-potent to known beta-antagonists in competition experiments of 125iodo-cyanopindolol binding in the rat hippocampus. |
1987-05-07 |
2023-08-11 |
rat |
| E Edwards, P M Whitaker-Azmiti. Selective beta-antagonists are equally and highly potent at 5-HT sites in the rat hippocampus. Neuropharmacology. vol 26. issue 1. 1987-05-07. PMID:2882439. |
saturation experiments demonstrated that in the rat hippocampus, a subpopulation of serotonin recognition sites comprised 50% of 125i-cyp binding. |
1987-05-07 |
2023-08-11 |
rat |
| M T Hsieh, H C Chen, H C Kao, T Shibuy. Suanzaorentang, and anxiolytic Chinese medicine, affects the central adrenergic and serotonergic systems in rats. Proceedings of the National Science Council, Republic of China. Part B, Life sciences. vol 10. issue 4. 1987-04-29. PMID:2882534. |
in this study, we found that 5-hydroxytryptophan (5-htp) induced decrease in locomotor activity was significantly antagonized by suanzaorentang, p-chlorophenylalanine (p-cpa) induced increase in locomotor activity was significantly inhibited by suanzaorentang, suanzaorentang had no significant effects on baclofen, muscimol, aminooxyacetic acid (aoaa) and thiosemicarbazide induced changes in locomotor activity, suanzaorentang significantly decreased vanillylmandelic acid (vma) in striatum and hippocampus, homovanillic acid (hva) in hippocampus and 5-hydroxyindol acetic acid (5-hiaa) in striatum and hypothalamus, suanzaorentang significantly reversed the alpha-methyltyrosine (alpha-mt) produced decrease in da concentrations in striatum and hippocampus, and (6) suanzaorentang significantly reversed the p-cpa produced decrease in 5-ht concentrations on amygdala. |
1987-04-29 |
2023-08-11 |
rat |
| J A Scott, F T Crew. Down-regulation of serotonin2, but not of beta-adrenergic receptors during chronic treatment with amitriptyline is independent of stimulation of serotonin2 and beta-adrenergic receptors. Neuropharmacology. vol 25. issue 12. 1987-04-29. PMID:3031528. |
in addition, the depletion of central stores of norepinephrine and serotonin by a 4-day treatment with reserpine (5 mg/kg per day) increased binding to beta receptors in the cerebral cortex and hippocampus, but did not affect binding to 5-ht2 receptors in either region. |
1987-04-29 |
2023-08-11 |
Not clear |
| D H Versteeg, W J Florij. Phorbol 12,13-dibutyrate enhances electrically stimulated neuromessenger release from rat dorsal hippocampal slices in vitro. Life sciences. vol 40. issue 13. 1987-04-27. PMID:2882398. |
the protein kinase c activator 4 beta-phorbol 12,13-dibutyrate (pdb) enhanced the electrically stimulated release of radiolabelled noradrenaline (na), acetylcholine (ach) and 5-hydroxytryptamine (5-ht) from dorsal hippocampal slices of the rat in vitro in a concentration-dependent manner. |
1987-04-27 |
2023-08-11 |
rat |
| D H Versteeg, W J Florij. Phorbol 12,13-dibutyrate enhances electrically stimulated neuromessenger release from rat dorsal hippocampal slices in vitro. Life sciences. vol 40. issue 13. 1987-04-27. PMID:2882398. |
taken together, the present data suggest that the diacylglycerol/protein kinase c pathway is involved in the stimulus-evoked release of na, ach and 5-ht from dorsal hippocampal nerve terminals. |
1987-04-27 |
2023-08-11 |
rat |
| F Besnard, E Kempf, G Fuhrmann, J Kempf, A Ebe. Influence of mouse genotype on responses of central biogenic amines to alcohol intoxication and aging. Alcohol (Fayetteville, N.Y.). vol 3. issue 6. 1987-04-22. PMID:3814344. |
dopamine and serotonin responses to various periods of alcohol treatment have been followed in striatum and hippocampus of two inbred strains of mice and related to the effect of aging. |
1987-04-22 |
2023-08-11 |
mouse |
| G Maura, E Roccatagliata, M Raiter. Serotonin autoreceptor in rat hippocampus: pharmacological characterization as a subtype of the 5-HT1 receptor. Naunyn-Schmiedeberg's archives of pharmacology. vol 334. issue 4. 1987-04-20. PMID:3821924. |
serotonin autoreceptor in rat hippocampus: pharmacological characterization as a subtype of the 5-ht1 receptor. |
1987-04-20 |
2023-08-11 |
rat |