| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Markstein, D Hoyer, G Enge. 5-HT1A-receptors mediate stimulation of adenylate cyclase in rat hippocampus. Naunyn-Schmiedeberg's archives of pharmacology. vol 333. issue 4. 1986-12-12. PMID:2945992. |
serotonin (5-ht) stimulated adenylate cyclase activity in homogenates of rat hippocampus. |
1986-12-12 |
2023-08-11 |
rat |
| R Markstein, D Hoyer, G Enge. 5-HT1A-receptors mediate stimulation of adenylate cyclase in rat hippocampus. Naunyn-Schmiedeberg's archives of pharmacology. vol 333. issue 4. 1986-12-12. PMID:2945992. |
the rank order of potency of 13 agonists stimulating adenylate cyclase activity in homogenates of rat hippocampus was in good agreement with the rank order of affinity of these agonists for the 5-ht1a binding site: n,n-dipropyl-5-carboxamidotryptamine (dp-5-ct) greater than 5-carboxamidotryptamine (5-ct) greater than 8-oh-dpat greater than 5-ht greater than 5-methoxytryptamine (5-och3t) greater than d-lsd greater than 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1h-indole (ru 24969) greater than alpha-methylserotonin (alpha-ch3-5-ht) greater than dopamine greater than 2-methylserotonin (2-ch3-5-ht). |
1986-12-12 |
2023-08-11 |
rat |
| H K Kimelberg, D M Kat. Regional differences in 5-hydroxytryptamine and catecholamine uptake in primary astrocyte cultures. Journal of neurochemistry. vol 47. issue 5. 1986-11-19. PMID:3531407. |
the uptake of 3h-labelled 5-hydroxytryptamine (5-ht, serotonin) norepinephrine ([3h]ne), and 3,4-dihydroxyphenylethylamine ([ 3h]dopamine, [3h]da) was studied in primary astrocyte cultures prepared from the cerebral cortex, corpus striatum, and hippocampal regions of neonatal rat brain. |
1986-11-19 |
2023-08-11 |
rat |
| H K Kimelberg, D M Kat. Regional differences in 5-hydroxytryptamine and catecholamine uptake in primary astrocyte cultures. Journal of neurochemistry. vol 47. issue 5. 1986-11-19. PMID:3531407. |
for [3h]5-ht the magnitude of uptake was corpus striatum greater than or equal to cerebral cortex greater than hippocampus, whereas for [3h]ne the order was hippocampus greater than corpus striatum greater than cerebral cortex. |
1986-11-19 |
2023-08-11 |
rat |
| J M Palacios, R Markstein, A Pazo. Serotonin-1C sites in the choroid plexus are not linked in a stimulatory or inhibitory way to adenylate cyclase. Brain research. vol 380. issue 1. 1986-11-13. PMID:3019464. |
the binding of [3h]serotonin to choroid plexus membranes was also unaffected by gppnhp while a dose-dependent decrease was observed in pig cortical and hippocampal membranes. |
1986-11-13 |
2023-08-11 |
rat |
| J M Palacios, R Markstein, A Pazo. Serotonin-1C sites in the choroid plexus are not linked in a stimulatory or inhibitory way to adenylate cyclase. Brain research. vol 380. issue 1. 1986-11-13. PMID:3019464. |
while forskolin-stimulated adenylate cyclase in the rat hippocampus was inhibited by serotonin forskolin-stimulated adenylate cyclase in the choroid plexus was insensitive to serotonin. |
1986-11-13 |
2023-08-11 |
rat |
| M B Emerit, H Gozlan, A Marquet, M Hamo. Irreversible blockade of central 5-HT1A receptor binding sites by the photoaffinity probe 8-methoxy-3'-NAP-amino-PAT. European journal of pharmacology. vol 127. issue 1-2. 1986-11-10. PMID:2944752. |
in the dark, this compound, 8-methoxy-2-(n-n-propyl,n-3-(2-nitro-4-azidophenyl)aminopropyl) aminotetralin or 8-methoxy-3'-nap-amino-pat, displaced [3h]8-oh-dpat and [3h]5-ht bound to 5-ht1a and 5-ht1 sites in hippocampal membranes with ic50 values of 6.6 and 18.1 nm respectively. |
1986-11-10 |
2023-08-11 |
rat |
| A V Juorio, A J Greenshaw, A A Boulto. Effects of acute and chronic phenelzine on regional monoamine metabolism in rats and its potentiation by deuterium substitution. Naunyn-Schmiedeberg's archives of pharmacology. vol 333. issue 3. 1986-10-30. PMID:2429193. |
the following brain regions and compounds were assessed using high performance liquid chromatography with electrochemical detection: striatum: dopamine, dopac, hva, 5-ht, 5-hiaa; hypothalamus: dopamine, 5-ht, 5-hiaa, noradrenaline; hippocampus: 5-ht, 5-hiaa, noradrenaline; frontal cortex: dopamine, noradrenaline, 5-ht, 5-hiaa. |
1986-10-30 |
2023-08-11 |
rat |
| T J Feuerstein, G Herttin. Serotonin (5-HT) enhances hippocampal noradrenaline (NA) release: evidence for facilitatory 5-HT receptors within the CNS. Naunyn-Schmiedeberg's archives of pharmacology. vol 333. issue 3. 1986-10-30. PMID:3762733. |
serotonin (5-ht) enhances hippocampal noradrenaline (na) release: evidence for facilitatory 5-ht receptors within the cns. |
1986-10-30 |
2023-08-11 |
rabbit |
| R W Ransom, K B Asarch, J C Shi. Photoaffinity labeling of the 5-hydroxytryptamine 1A receptor in rat hippocampus. Journal of neurochemistry. vol 47. issue 4. 1986-10-15. PMID:3746296. |
photoaffinity labeling of the 5-hydroxytryptamine 1a receptor in rat hippocampus. |
1986-10-15 |
2023-08-11 |
rat |
| M R Pranzatelli, S R Snodgras. Enhanced selective 5-HT depletions in the DHT rat model: denervation supersensitivity and recovery of function. Psychopharmacology. vol 89. issue 4. 1986-10-01. PMID:3092275. |
after four dht injections, 5-ht content in septum/accumbens, hippocampus, striatum, neocortex, cerebellum, and cervical spinal cord fell to 0-10% of controls. |
1986-10-01 |
2023-08-11 |
rat |
| M R Pranzatelli, S R Snodgras. Enhanced selective 5-HT depletions in the DHT rat model: denervation supersensitivity and recovery of function. Psychopharmacology. vol 89. issue 4. 1986-10-01. PMID:3092275. |
multiple regression of lma with regional 5-ht content was significant for hippocampus, striatum, and septum/accumbens. |
1986-10-01 |
2023-08-11 |
rat |
| T J Feuerstein, G Hertting, A Lupp, B Neufan. False labelling of dopaminergic terminals in the rabbit caudate nucleus: uptake and release of [3H]-5-hydroxytryptamine. British journal of pharmacology. vol 88. issue 3. 1986-09-26. PMID:3742155. |
the effect of the catecholamine uptake inhibitor nomifensine and of the 5-hydroxytryptamine (5-ht) uptake blocker 6-nitroquipazine on the accumulation of [3h]-5-ht (0.1 microm, 60 min incubation) and [3h]-dopamine (0.1 microm, 30 min incubation) into slices of hippocampus and caudate nucleus of the rabbit was investigated. |
1986-09-26 |
2023-08-11 |
rabbit |
| T J Feuerstein, G Hertting, A Lupp, B Neufan. False labelling of dopaminergic terminals in the rabbit caudate nucleus: uptake and release of [3H]-5-hydroxytryptamine. British journal of pharmacology. vol 88. issue 3. 1986-09-26. PMID:3742155. |
in the hippocampus both ly 171555 and domperidone were completely ineffective in modulating 5-ht release regardless of the absence or presence of nomifensine. |
1986-09-26 |
2023-08-11 |
rabbit |
| G L Wenk, K L Engisc. [3H]ketanserin (serotonin type 2) binding increases in rat cortex following basal forebrain lesions with ibotenic acid. Journal of neurochemistry. vol 47. issue 3. 1986-09-25. PMID:2942641. |
the density of 5-hydroxytryptamine (serotonin) type 2 (s2) receptor sites in the frontal cortex and hippocampus was determined 1 week and 4 months after production of lesions by injections of ibotenic acid into the medial septum and nucleus basalis magnocellularis. |
1986-09-25 |
2023-08-11 |
rat |
| G L Wenk, K L Engisc. [3H]ketanserin (serotonin type 2) binding increases in rat cortex following basal forebrain lesions with ibotenic acid. Journal of neurochemistry. vol 47. issue 3. 1986-09-25. PMID:2942641. |
four months later, the number of [3h]ketanserin binding sites (and bmax) was increased and high-affinity [3h]serotonin uptake was decreased in the frontal neocortex, but not in the hippocampus, relative to unlesioned controls. |
1986-09-25 |
2023-08-11 |
rat |
| A V Martynenko, S V Magaeva, L A Basharova, M V Martynenk. [Autoimmune reactions in experimental pathology of the hippocampus]. Biulleten' eksperimental'noi biologii i meditsiny. vol 102. issue 7. 1986-09-25. PMID:3730573. |
experimental hippocampal pathology caused by the local electrolytic lesion of the dorsal hippocampal area was shown to induce synthesis of antibodies to neurotransmitters (epinephrine and serotonin) and to hippocampal, heart and lung tissue antigens. |
1986-09-25 |
2023-08-11 |
Not clear |
| M D Hall, H Gozlan, M B Emerit, S el Mestikawy, L Pichat, M Hamo. Differentiation of pre- and post-synaptic high affinity serotonin receptor binding sites using physico-chemical parameters and modifying agents. Neurochemical research. vol 11. issue 6. 1986-09-17. PMID:3016581. |
in contrast, both [3h]5-ht and [3h]8-oh-dpat binding were increased by the cation in hippocampal membranes. |
1986-09-17 |
2023-08-11 |
rat |
| M D Hall, H Gozlan, M B Emerit, S el Mestikawy, L Pichat, M Hamo. Differentiation of pre- and post-synaptic high affinity serotonin receptor binding sites using physico-chemical parameters and modifying agents. Neurochemical research. vol 11. issue 6. 1986-09-17. PMID:3016581. |
conversely, gtp reduced the binding of either ligand in the hippocampus but affected only [3h]5-ht binding in the striatum. |
1986-09-17 |
2023-08-11 |
rat |
| M D Hall, H Gozlan, M B Emerit, S el Mestikawy, L Pichat, M Hamo. Differentiation of pre- and post-synaptic high affinity serotonin receptor binding sites using physico-chemical parameters and modifying agents. Neurochemical research. vol 11. issue 6. 1986-09-17. PMID:3016581. |
furthermore, n-ethylmaleimide inhibited equally [3h]5-ht and [3h]8-oh-dpat binding to hippocampal membranes, but was markedly less potent against [3h]8-oh-dpat binding to striatal membranes. |
1986-09-17 |
2023-08-11 |
rat |