| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D A Peter. Prenatal stress: effect on development of rat brain serotonergic neurons. Pharmacology, biochemistry, and behavior. vol 24. issue 5. 1986-08-04. PMID:3725840. |
[3h]5-ht binding was increased in cerebral cortex, decreased in hippocampus and unchanged in pons medulla while [3h]spiperone binding was increased in all three regions at 60 days of age. |
1986-08-04 |
2023-08-11 |
rat |
| D A Peter. Prenatal stress: effect on development of rat brain serotonergic neurons. Pharmacology, biochemistry, and behavior. vol 24. issue 5. 1986-08-04. PMID:3725840. |
prenatal stress reduced the rate of [14c]5-ht synthesis in hippocampus but not in cortex or pons medulla. |
1986-08-04 |
2023-08-11 |
rat |
| F C Zhou, E C Azmiti. Induced homotypic sprouting of serotonergic fibers in hippocampus. II. An immunocytochemistry study. Brain research. vol 373. issue 1-2. 1986-07-25. PMID:3013362. |
the dorsal hippocampus of the rat normally receives its 5-ht innervation from two homologous groups of cells in the median raphe nucleus via the cingulum bundle-induseum griseum (cb-ig) and the fornix-fimbria (ff) (j. comp. |
1986-07-25 |
2023-08-11 |
rat |
| F C Zhou, E C Azmiti. Induced homotypic sprouting of serotonergic fibers in hippocampus. II. An immunocytochemistry study. Brain research. vol 373. issue 1-2. 1986-07-25. PMID:3013362. |
5-ht immunoreactive (ir) fibers are distributed in a laminar pattern in the hippocampus. |
1986-07-25 |
2023-08-11 |
rat |
| S I Harik, S Yoshida, R Busto, M D Ginsber. Monoamine neurotransmitters in diffuse reversible forebrain ischemia and early recirculation: increased dopaminergic activity. Neurology. vol 36. issue 7. 1986-07-23. PMID:2872620. |
norepinephrine and serotonin decreased in the cerebral cortex and hippocampus during ischemia and diminished further during recirculation. |
1986-07-23 |
2023-08-11 |
rat |
| R F Seegal, K O Brosch, B Bus. Regional alterations in serotonin metabolism induced by oral exposure of rats to polychlorinated biphenyls. Neurotoxicology. vol 7. issue 1. 1986-07-14. PMID:2423934. |
total pcb concentrations and concentrations of serotonin and its major central metabolite, 5-hydroxyindoleacetic acid, were determined in the dorsal frontal cortex, lateral olfactory tract, hippocampus, medial-basal hypothalamus and brainstem. |
1986-07-14 |
2023-08-11 |
rat |
| R F Seegal, K O Brosch, B Bus. Regional alterations in serotonin metabolism induced by oral exposure of rats to polychlorinated biphenyls. Neurotoxicology. vol 7. issue 1. 1986-07-14. PMID:2423934. |
serotonin concentrations were reduced in frontal cortex and hippocampus, unaffected in hypothalamus and brainstem and elevated in lateral olfactory tract. |
1986-07-14 |
2023-08-11 |
rat |
| P M Hudson, H A Tilson, P H Chen, J S Hon. Neurobehavioral effects of permethrin are associated with alterations in regional levels of biogenic amine metabolites and amino acid neurotransmitters. Neurotoxicology. vol 7. issue 1. 1986-07-14. PMID:2872638. |
neurochemical analyses of regional biogenic amines and their metabolites and amino acids 5 hrs after 90 or 180 mg/kg indicated that 5-hiaa levels were increased in the hypothalamus (hyp), brain stem (bs), hippocampus (hpc), and striatum (str); 5-ht was not affected. |
1986-07-14 |
2023-08-11 |
rat |
| M Orosco, J H Trouvin, Y Cohen, C Jacquo. Ontogeny of brain monoamines in lean and obese female Zucker rats. Physiology & behavior. vol 36. issue 5. 1986-07-02. PMID:2424037. |
at 16 weeks, increases of da and 5-ht in the hypothalamus and decreases of norepinephrine (ne), 5-ht and 5-hiaa in the hippocampus appeared. |
1986-07-02 |
2023-08-11 |
rat |
| G G Gasanov, E M Melikov, G D Movsumo. [Comparison of the effect of serotonin administered into the dorsal hippocampus on conditioned passive and active avoidance in rats]. Biulleten' eksperimental'noi biologii i meditsiny. vol 101. issue 5. 1986-07-02. PMID:3708128. |
[comparison of the effect of serotonin administered into the dorsal hippocampus on conditioned passive and active avoidance in rats]. |
1986-07-02 |
2023-08-11 |
rat |
| T Nishikawa, B Scatto. Neuroanatomical site of the inhibitory influence of anxiolytic drugs on central serotonergic transmission. Brain research. vol 371. issue 1. 1986-06-30. PMID:2871894. |
systemic administration of diazepam (3 mg/kg s.c.) or flunitrazepam (1 mg/kg, s.c.) caused a reduction of 5-ht synthesis (as measured by the accumulation of 5-hydroxytryptophan after inhibition of aromatic amino acid decarboxylase) in the hippocampus but not in the cerebral cortex, striatum, cerebellum or spinal cord of the rat. |
1986-06-30 |
2023-08-11 |
rat |
| T Nishikawa, B Scatto. Neuroanatomical site of the inhibitory influence of anxiolytic drugs on central serotonergic transmission. Brain research. vol 371. issue 1. 1986-06-30. PMID:2871894. |
the decrease of hippocampal 5-ht synthesis induced by diazepam (5 mg/kg, s.c.) was antagonized by the benzodiazepine antagonist ro 15-1788 (2 x 30 mg/kg, s.c.) but not by bicuculline (2 x 1 mg/kg, s.c.). |
1986-06-30 |
2023-08-11 |
rat |
| T Nishikawa, B Scatto. Neuroanatomical site of the inhibitory influence of anxiolytic drugs on central serotonergic transmission. Brain research. vol 371. issue 1. 1986-06-30. PMID:2871894. |
to diminish hippocampal 5-ht synthesis. |
1986-06-30 |
2023-08-11 |
rat |
| T Nishikawa, B Scatto. Neuroanatomical site of the inhibitory influence of anxiolytic drugs on central serotonergic transmission. Brain research. vol 371. issue 1. 1986-06-30. PMID:2871894. |
local infusion of diazepam (15 micrograms) of flurazepam (1.5 micrograms) into the hippocampus of conscious rats (via indwelling cannulae) markedly reduced 5-ht synthesis in this brain area whereas infusion of these drugs into the raphé medianus (origin of the serotonergic afferents to the hippocampus) failed to affect hippocampal 5-ht synthesis. |
1986-06-30 |
2023-08-11 |
rat |
| T Nishikawa, B Scatto. Neuroanatomical site of the inhibitory influence of anxiolytic drugs on central serotonergic transmission. Brain research. vol 371. issue 1. 1986-06-30. PMID:2871894. |
in contrast, local injection of muscimol (25-150 ng) into the raphé medianus reduced 5-ht synthesis in the hippocampus. |
1986-06-30 |
2023-08-11 |
rat |
| B Scatton, Y Claustre, T Dennis, T Nishikaw. Zolpidem, a novel nonbenzodiazepine hypnotic. II. Effects on cerebellar cyclic GMP levels and cerebral monoamines. The Journal of pharmacology and experimental therapeutics. vol 237. issue 2. 1986-06-23. PMID:2871179. |
however, the compound (10-30 mg/kg) diminished serotonin synthesis in the hippocampus, striatum and frontal cortex. |
1986-06-23 |
2023-08-11 |
mouse |
| M H Bassant, M Picard, D Olichon, F Cathala, L Cour. Changes in the serotonergic, noradrenergic and dopaminergic levels in the brain of scrapie-infected rats. Brain research. vol 367. issue 1-2. 1986-06-09. PMID:2421836. |
scrapie-infected rats showed a reduction in the levels of 5-ht and 5-hiaa (frontal cortex, hippocampus, mesolimbic structure). |
1986-06-09 |
2023-08-11 |
mouse |
| E B De Souza, G R Van Loo. Brain serotonin and catecholamine responses to repeated stress in rats. Brain research. vol 367. issue 1-2. 1986-06-09. PMID:2421837. |
in addition, the synthesis rate of 5-ht in anterior hypothalamus, posterior hypothalamus, hippocampus and brainstem was not altered by a second stress applied 90 min after the initial stress. |
1986-06-09 |
2023-08-11 |
rat |
| L Rönnbäck, E Hansson, A Cupello, M V Rapallino, J Zeuchner, L Rosengre. Neurotransmitter uptake in various brain regions of chronically morphinized rats. Neurochemical research. vol 11. issue 2. 1986-06-02. PMID:2871500. |
[3h]glutamate and [3h]gaba uptakes were also significantly lower, respectively, in frontal cortex, hippocampus and brain stem in intoxicated rats, while [3h]5-ht uptake was significantly lower in hypothalamus after morphine withdrawal. |
1986-06-02 |
2023-08-11 |
rat |
| T Mennini, M Gobbi, F Ponzio, S Garattin. Neurochemical effects of buspirone in rat hippocampus: evidence for selective activation of 5HT neurons. Archives internationales de pharmacodynamie et de therapie. vol 279. issue 1. 1986-05-22. PMID:2421657. |
neurochemical effects of buspirone in rat hippocampus: evidence for selective activation of 5ht neurons. |
1986-05-22 |
2023-08-11 |
rat |