| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Glaser, M Rath, J Traber, K Zilles, A Schleiche. Autoradiographic identification and topographical analyses of high affinity serotonin receptor subtypes as a target for the novel putative anxiolytic TVX Q 7821. Brain research. vol 358. issue 1-2. 1986-02-18. PMID:2866816. |
color coded autoradiograms obtained either with [3h]5-ht or [3h]tvx q 7821 showed a nearly identical pattern of labeling with high receptor densities in the hippocampus, the entorhinal area, the septum, the interpeduncular nucleus and the dorsal raphe. |
1986-02-18 |
2023-08-11 |
rat |
| P D Hrdina, B A Pappas, D C Roberts, R J Bialik, C L Rya. Relationship between levels and uptake of serotonin and high affinity [3H]imipramine recognition sites in the rat brain. Canadian journal of physiology and pharmacology. vol 63. issue 10. 1986-02-17. PMID:3000552. |
neonatal treatment with 5,7-dht resulted in a significant decrease of both serotonin levels and density (bmax) of high affinity [3h]imipramine binding sites in the hippocampus. |
1986-02-17 |
2023-08-11 |
rat |
| P F Gately, S L Poon, D S Segal, M A Geye. Depletion of brain serotonin by 5,7-dihydroxytryptamine alters the response to amphetamine and the habituation of locomotor activity in rats. Psychopharmacology. vol 87. issue 4. 1986-02-17. PMID:3936096. |
in a separate set of animals, liquid chromatographic assays revealed that this treatment did not significantly alter catecholamine levels but depleted hippocampal 5ht by 80-90% and caudate 5ht by 30-42% as early as 24 h after administration of 5,7-dht. |
1986-02-17 |
2023-08-11 |
rat |
| M A Geyer, J Gordon, L M Adam. Behavioral effects of xylamine-induced depletions of brain norepinephrine: interaction with LSD. Pharmacology, biochemistry, and behavior. vol 23. issue 4. 1986-01-07. PMID:3877938. |
liquid chromatographic measures of brain monoamines confirmed that xylamine reduced hippocampal ne by 80.8% and hypothalamic ne by 26% without affecting levels of serotonin or dopamine. |
1986-01-07 |
2023-08-11 |
rat |
| S G Beck, W P Clarke, J Goldfar. Spiperone differentiates multiple 5-hydroxytryptamine responses in rat hippocampal slices in vitro. European journal of pharmacology. vol 116. issue 1-2. 1985-12-18. PMID:2932343. |
spiperone differentiates multiple 5-hydroxytryptamine responses in rat hippocampal slices in vitro. |
1985-12-18 |
2023-08-11 |
rat |
| A Mori, H Kabuto, Y Q Pe. Effects of piperine on convulsions and on brain serotonin and catecholamine levels in E1 mice. Neurochemical research. vol 10. issue 9. 1985-12-18. PMID:4058659. |
on the other hand, lower levels of 5-ht were observed in the hippocampus, midbrain and cerebellum. |
1985-12-18 |
2023-08-11 |
mouse |
| R J Waldbillig, G E Weider, R M Clemmons, T J Bartnes. Rostral hypothalamic microinfusions of 5,7 dihydroxytryptamine produce anatomically and neurochemically selective depletions of hippocampal serotonin and increase the influence of estrogen and food deprivation on locomotor activity. Brain research. vol 347. issue 1. 1985-12-13. PMID:4052795. |
rostral hypothalamic microinfusions of 5,7 dihydroxytryptamine produce anatomically and neurochemically selective depletions of hippocampal serotonin and increase the influence of estrogen and food deprivation on locomotor activity. |
1985-12-13 |
2023-08-11 |
rat |
| R J Waldbillig, G E Weider, R M Clemmons, T J Bartnes. Rostral hypothalamic microinfusions of 5,7 dihydroxytryptamine produce anatomically and neurochemically selective depletions of hippocampal serotonin and increase the influence of estrogen and food deprivation on locomotor activity. Brain research. vol 347. issue 1. 1985-12-13. PMID:4052795. |
neurochemical determination of catecholamines (ca) and indoleamines in the hippocampus, hypothalamus and mesencephalon revealed that 5,7-dht infusions had no effect on ca content in these areas nor in mesencephalic serotonin or 5-hydroxyindoleacetic acid (5-hiaa). |
1985-12-13 |
2023-08-11 |
rat |
| R J Waldbillig, G E Weider, R M Clemmons, T J Bartnes. Rostral hypothalamic microinfusions of 5,7 dihydroxytryptamine produce anatomically and neurochemically selective depletions of hippocampal serotonin and increase the influence of estrogen and food deprivation on locomotor activity. Brain research. vol 347. issue 1. 1985-12-13. PMID:4052795. |
however, the neurotoxin produced significant decreases in hippocampal serotonin and 5-hiaa. |
1985-12-13 |
2023-08-11 |
rat |
| K Mashek, L V Devoino, O Kadletsova, G V Idova, N B Morozov. [Changes in the level of serotonin in the brain and immunocompetent organs during the formation of the immune response]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. vol 71. issue 8. 1985-12-13. PMID:4054385. |
the serotonin content increased in adrenals within 20 min after immunization of rats with sheep red blood cells, and diminished in ventral part of the anterior hypothalamus, hippocampus and in thymus. |
1985-12-13 |
2023-08-11 |
rat |
| H Arito, H Tsuruta, K Nakagaki, S Tanak. Partial insomnia, hyperactivity and hyperdipsia induced by repeated administration of toluene in rats: their relation to brain monoamine metabolism. Toxicology. vol 37. issue 1-2. 1985-12-05. PMID:4060173. |
the toluene-induced partial insomnia and hyperactivity were associated with lowered concentrations of serotonin in frontal cortex, hippocampus and midbrain and 5-hydroxyindoleacetic acid in midbrain and hypothalamus. |
1985-12-05 |
2023-08-11 |
rat |
| C Molla-Hosseini, P M Lenicque, J Wepierre, Y Cohe. Behavior and kainic acids differential behavioral and biochemical effects of kainic acid and allokainic acid injections in rats. Journal de pharmacologie. vol 16. issue 2. 1985-11-25. PMID:4058013. |
ka caused also some significant changes in serotonin levels in hippocampus 6 days after injection while aka did not. |
1985-11-25 |
2023-08-11 |
rat |
| M Dowdall, C De Montign. Effect of atmospheric ions on hippocampal pyramidal neuron responsiveness to serotonin. Brain research. vol 342. issue 1. 1985-11-12. PMID:2412639. |
unitary extracellular recordings from pyramidal neurons of the ca1 and ca3 regions of the dorsal hippocampus were obtained under urethane anesthesia, and their responsiveness to microiontophoretically applied acetylcholine (ach), norepinephrine (ne) and 5-ht was assessed. |
1985-11-12 |
2023-08-11 |
rat |
| S J Peroutk. Selective labeling of 5-HT1A and 5-HT1B binding sites in bovine brain. Brain research. vol 344. issue 1. 1985-11-12. PMID:4041865. |
by contrast, 8-oh-dpat, tvx q 7821 and buspirone were significantly more potent at [3h]8-oh-dpat binding sites in bovine hippocampus than at [3h]5-ht binding sites in bovine striatum. |
1985-11-12 |
2023-08-11 |
cattle |
| S O Ogren, C Johansson, O Magnusso. Forebrain serotonergic involvement in avoidance learning. Neuroscience letters. vol 58. issue 3. 1985-11-06. PMID:2995878. |
injection of 5,7-dihydroxytryptamine (5,7-dht) into the forebrain in desipramine (20 mg/kg)-pretreated rats resulted in a 65-70% decrease in 5-ht concentrations in the prefrontal cortex and hippocampus without any significant effect on striatal 5-ht. |
1985-11-06 |
2023-08-11 |
rat |
| S O Ogren, C Johansson, O Magnusso. Forebrain serotonergic involvement in avoidance learning. Neuroscience letters. vol 58. issue 3. 1985-11-06. PMID:2995878. |
the 5,7-dht lesions markedly attenuated the impaired avoidance performance induced by pca (2.5 mg/kg), suggesting that the avoidance deficit depends on intact 5-ht terminals in cortex and/or hippocampus. |
1985-11-06 |
2023-08-11 |
rat |
| P Huttunen, B A Spencer, R D Myer. Monoamine transmitter release induced by tetrahydro-beta-carboline perfused in hippocampus of the unrestrained rat. Brain research bulletin. vol 15. issue 2. 1985-11-06. PMID:4041928. |
on recovery, a tissue site in the hippocampus was double-labelled with a 1.0 microliter volume of [14c]-5-hydroxytryptamine (5-ht) and [3h]-norepinephrine (ne). |
1985-11-06 |
2023-08-11 |
rat |
| C Aldinio, S Mazzari, G Toffano, C Köhler, R Schwarc. Effects of intracerebral injections of quinolinic acid on serotonergic neurons in the rat brain. Brain research. vol 341. issue 1. 1985-11-05. PMID:2412634. |
hippocampal serotonin turnover was assessed at 4 days after an intrahippocampal quin-application: following inhibition of aromatic amino acid decarboxylase, the accumulation of 5-hydroxytryptophan was twice as rapid in quin-lesioned hippocampi as in controls. |
1985-11-05 |
2023-08-11 |
rat |
| C A Stockmeier, A M Martino, K J Kella. A strong influence of serotonin axons on beta-adrenergic receptors in rat brain. Science (New York, N.Y.). vol 230. issue 4723. 1985-11-04. PMID:2996132. |
four to six weeks after the lesion, the uptake of 3h-labeled serotonin in the frontal cortex and the hippocampus was reduced by more than 90 percent, while neither the uptake of 3h-labeled norepinephrine nor the content of norepinephrine was affected in either tissue. |
1985-11-04 |
2023-08-11 |
rat |
| L K Chomicka, A M Koneck. Spontaneously prolonged dioestrus and serotonin in various regions of the rat brain. Journal of neural transmission. vol 63. issue 1. 1985-10-18. PMID:2411854. |
no significant difference was observed with 5-ht and 5-hiaa concentrations in the hippocampus (hipp). |
1985-10-18 |
2023-08-11 |
rat |