| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Markstei. Hydergine: interaction with the neurotransmitter systems in the central nervous system. Journal de pharmacologie. vol 16 Suppl 3. 1986-03-31. PMID:2869188. |
hydergine had also mixed agonist/antagonist properties at the serotonin-sensitive adenylate cyclase in the rat hippocampus and the presynaptic serotonin autoreceptors present on nerve terminals in the rat cortex. |
1986-03-31 |
2023-08-11 |
rat |
| J H Trouvin, M Prioux-Guyonneau, Y Cohen, C Jacquo. Rat brain monoamine metabolism and hypobaric hypoxia: a new approach. General pharmacology. vol 17. issue 1. 1986-03-31. PMID:3949151. |
a chromatographic method with electrochemical detection was used to measure noradrenaline (na), dopamine (da), and serotonin (5-ht), 3,4-dihydroxyphenylacetic acid (dopac), homovanillic acid (hva), 3-methoxytyramine (3-mt) and 5-hydroxyindoleacetic acid (5-hiaa) in several brain areas (hypothalamus, hippocampus, striatum and rest of the brain) of rats exposed to a 7000 m simulated altitude for 3 hr. |
1986-03-31 |
2023-08-11 |
rat |
| W Felińska, R Szkilnik, B Stanosek, M Kamiński, K Ludyga, R Bru. [Effect of chronic exposure to nitrogen dioxide on biogenic amine levels in the brain of guinea pigs]. Medycyna pracy. vol 36. issue 4. 1986-03-14. PMID:2418330. |
the tissues were kept for 2-3 days at -20 degrees c, and afterwards the content of noradrenaline, 5-hydroxytryptamine and 5-hydroxyindole-acetic acid was estimated spectrofluorometrically in examined parts of the brain (thalamus--hypothalamus pons + medulla oblongata hippocampus, cortex frontalis). |
1986-03-14 |
2023-08-11 |
Not clear |
| F Owen, D R Chambers, S J Cooper, T J Crow, J A Johnson, R Lofthouse, M Poulte. Serotonergic mechanisms in brains of suicide victims. Brain research. vol 362. issue 1. 1986-02-24. PMID:2417665. |
the concentrations of 5-hydroxytryptamine (serotonin; 5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) were determined in occipital cortex and hippocampus and the high-affinity binding of ligands to the 5-ht1, 5-ht2 and imipramine-binding sites was assessed in frontal cortex, occipital cortex and hippocampus. |
1986-02-24 |
2023-08-11 |
Not clear |
| S Auerbach, F Zhou, B L Jacobs, E Azmiti. Serotonin turnover in raphe neurons transplanted into rat hippocampus. Neuroscience letters. vol 61. issue 1-2. 1986-02-18. PMID:2417169. |
serotonin turnover in raphe neurons transplanted into rat hippocampus. |
1986-02-18 |
2023-08-11 |
rat |
| S Auerbach, F Zhou, B L Jacobs, E Azmiti. Serotonin turnover in raphe neurons transplanted into rat hippocampus. Neuroscience letters. vol 61. issue 1-2. 1986-02-18. PMID:2417169. |
injections of the neurotoxin, 5,7-dihydroxytryptamine, into rostral raphe nuclei in rats reduced serotonin (5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) in hippocampus to 35-50% of normal levels but only reduced 5-ht synthesis and catabolism by 20-35%. |
1986-02-18 |
2023-08-11 |
rat |
| S Auerbach, F Zhou, B L Jacobs, E Azmiti. Serotonin turnover in raphe neurons transplanted into rat hippocampus. Neuroscience letters. vol 61. issue 1-2. 1986-02-18. PMID:2417169. |
transplantation of rat fetal raphe cells into the 5-ht-denervated hippocampus restored 5-ht and 5-hiaa levels and 5-ht synthesis to 125-150% of normal. |
1986-02-18 |
2023-08-11 |
rat |
| S Auerbach, F Zhou, B L Jacobs, E Azmiti. Serotonin turnover in raphe neurons transplanted into rat hippocampus. Neuroscience letters. vol 61. issue 1-2. 1986-02-18. PMID:2417169. |
this demonstrates that transplantation of fetal raphe tissue can restore metabolism to normal levels in the 5-ht denervated hippocampus. |
1986-02-18 |
2023-08-11 |
rat |
| T Glaser, M Rath, J Traber, K Zilles, A Schleiche. Autoradiographic identification and topographical analyses of high affinity serotonin receptor subtypes as a target for the novel putative anxiolytic TVX Q 7821. Brain research. vol 358. issue 1-2. 1986-02-18. PMID:2866816. |
color coded autoradiograms obtained either with [3h]5-ht or [3h]tvx q 7821 showed a nearly identical pattern of labeling with high receptor densities in the hippocampus, the entorhinal area, the septum, the interpeduncular nucleus and the dorsal raphe. |
1986-02-18 |
2023-08-11 |
rat |
| P D Hrdina, B A Pappas, D C Roberts, R J Bialik, C L Rya. Relationship between levels and uptake of serotonin and high affinity [3H]imipramine recognition sites in the rat brain. Canadian journal of physiology and pharmacology. vol 63. issue 10. 1986-02-17. PMID:3000552. |
neonatal treatment with 5,7-dht resulted in a significant decrease of both serotonin levels and density (bmax) of high affinity [3h]imipramine binding sites in the hippocampus. |
1986-02-17 |
2023-08-11 |
rat |
| P F Gately, S L Poon, D S Segal, M A Geye. Depletion of brain serotonin by 5,7-dihydroxytryptamine alters the response to amphetamine and the habituation of locomotor activity in rats. Psychopharmacology. vol 87. issue 4. 1986-02-17. PMID:3936096. |
in a separate set of animals, liquid chromatographic assays revealed that this treatment did not significantly alter catecholamine levels but depleted hippocampal 5ht by 80-90% and caudate 5ht by 30-42% as early as 24 h after administration of 5,7-dht. |
1986-02-17 |
2023-08-11 |
rat |
| M A Geyer, J Gordon, L M Adam. Behavioral effects of xylamine-induced depletions of brain norepinephrine: interaction with LSD. Pharmacology, biochemistry, and behavior. vol 23. issue 4. 1986-01-07. PMID:3877938. |
liquid chromatographic measures of brain monoamines confirmed that xylamine reduced hippocampal ne by 80.8% and hypothalamic ne by 26% without affecting levels of serotonin or dopamine. |
1986-01-07 |
2023-08-11 |
rat |
| S G Beck, W P Clarke, J Goldfar. Spiperone differentiates multiple 5-hydroxytryptamine responses in rat hippocampal slices in vitro. European journal of pharmacology. vol 116. issue 1-2. 1985-12-18. PMID:2932343. |
spiperone differentiates multiple 5-hydroxytryptamine responses in rat hippocampal slices in vitro. |
1985-12-18 |
2023-08-11 |
rat |
| A Mori, H Kabuto, Y Q Pe. Effects of piperine on convulsions and on brain serotonin and catecholamine levels in E1 mice. Neurochemical research. vol 10. issue 9. 1985-12-18. PMID:4058659. |
on the other hand, lower levels of 5-ht were observed in the hippocampus, midbrain and cerebellum. |
1985-12-18 |
2023-08-11 |
mouse |
| R J Waldbillig, G E Weider, R M Clemmons, T J Bartnes. Rostral hypothalamic microinfusions of 5,7 dihydroxytryptamine produce anatomically and neurochemically selective depletions of hippocampal serotonin and increase the influence of estrogen and food deprivation on locomotor activity. Brain research. vol 347. issue 1. 1985-12-13. PMID:4052795. |
rostral hypothalamic microinfusions of 5,7 dihydroxytryptamine produce anatomically and neurochemically selective depletions of hippocampal serotonin and increase the influence of estrogen and food deprivation on locomotor activity. |
1985-12-13 |
2023-08-11 |
rat |
| R J Waldbillig, G E Weider, R M Clemmons, T J Bartnes. Rostral hypothalamic microinfusions of 5,7 dihydroxytryptamine produce anatomically and neurochemically selective depletions of hippocampal serotonin and increase the influence of estrogen and food deprivation on locomotor activity. Brain research. vol 347. issue 1. 1985-12-13. PMID:4052795. |
neurochemical determination of catecholamines (ca) and indoleamines in the hippocampus, hypothalamus and mesencephalon revealed that 5,7-dht infusions had no effect on ca content in these areas nor in mesencephalic serotonin or 5-hydroxyindoleacetic acid (5-hiaa). |
1985-12-13 |
2023-08-11 |
rat |
| R J Waldbillig, G E Weider, R M Clemmons, T J Bartnes. Rostral hypothalamic microinfusions of 5,7 dihydroxytryptamine produce anatomically and neurochemically selective depletions of hippocampal serotonin and increase the influence of estrogen and food deprivation on locomotor activity. Brain research. vol 347. issue 1. 1985-12-13. PMID:4052795. |
however, the neurotoxin produced significant decreases in hippocampal serotonin and 5-hiaa. |
1985-12-13 |
2023-08-11 |
rat |
| K Mashek, L V Devoino, O Kadletsova, G V Idova, N B Morozov. [Changes in the level of serotonin in the brain and immunocompetent organs during the formation of the immune response]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. vol 71. issue 8. 1985-12-13. PMID:4054385. |
the serotonin content increased in adrenals within 20 min after immunization of rats with sheep red blood cells, and diminished in ventral part of the anterior hypothalamus, hippocampus and in thymus. |
1985-12-13 |
2023-08-11 |
rat |
| H Arito, H Tsuruta, K Nakagaki, S Tanak. Partial insomnia, hyperactivity and hyperdipsia induced by repeated administration of toluene in rats: their relation to brain monoamine metabolism. Toxicology. vol 37. issue 1-2. 1985-12-05. PMID:4060173. |
the toluene-induced partial insomnia and hyperactivity were associated with lowered concentrations of serotonin in frontal cortex, hippocampus and midbrain and 5-hydroxyindoleacetic acid in midbrain and hypothalamus. |
1985-12-05 |
2023-08-11 |
rat |
| C Molla-Hosseini, P M Lenicque, J Wepierre, Y Cohe. Behavior and kainic acids differential behavioral and biochemical effects of kainic acid and allokainic acid injections in rats. Journal de pharmacologie. vol 16. issue 2. 1985-11-25. PMID:4058013. |
ka caused also some significant changes in serotonin levels in hippocampus 6 days after injection while aka did not. |
1985-11-25 |
2023-08-11 |
rat |