| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M D Hall, H Gozlan, M B Emerit, S el Mestikawy, L Pichat, M Hamo. Differentiation of pre- and post-synaptic high affinity serotonin receptor binding sites using physico-chemical parameters and modifying agents. Neurochemical research. vol 11. issue 6. 1986-09-17. PMID:3016581. |
[3h]8-oh-dpat hl binding sites were particularly abundant in the hippocampus, septum and cerebral cortex, and exhibited pharmacological properties typical of the postsynaptic 5-ht1a subsites previously characterized with [3h]5-ht as the ligand. |
1986-09-17 |
2023-08-11 |
rat |
| D Scherma. Dihydrotetrabenazine binding and monoamine uptake in mouse brain regions. Journal of neurochemistry. vol 47. issue 2. 1986-09-17. PMID:3734781. |
binding of [2-3h]dihydrotetrabenazine and uptake of 5-hydroxytryptamine (serotonin) were studied in mouse brain cerebellum, pons-medulla, frontal cortex, hypothalamus, hippocampus, and striatum. |
1986-09-17 |
2023-08-11 |
mouse |
| P H Wu, C A Naranjo, T Fa. Chronic ethanol inhibits rat hippocampal "stimulus-secretion" coupling mechanism for 5-hydroxytryptamine in vitro. Neurochemical research. vol 11. issue 6. 1986-09-17. PMID:3736767. |
chronic ethanol inhibits rat hippocampal "stimulus-secretion" coupling mechanism for 5-hydroxytryptamine in vitro. |
1986-09-17 |
2023-08-11 |
rat |
| P H Wu, C A Naranjo, T Fa. Chronic ethanol inhibits rat hippocampal "stimulus-secretion" coupling mechanism for 5-hydroxytryptamine in vitro. Neurochemical research. vol 11. issue 6. 1986-09-17. PMID:3736767. |
chronic ethanol (10 g/kg/day) for 6 days inhibited [14c]5-ht release from hippocampus whereas it did not affect [14c]5-ht release from hypothalamus. |
1986-09-17 |
2023-08-11 |
rat |
| M De Vivo, S Maayan. Characterization of the 5-hydroxytryptamine1a receptor-mediated inhibition of forskolin-stimulated adenylate cyclase activity in guinea pig and rat hippocampal membranes. The Journal of pharmacology and experimental therapeutics. vol 238. issue 1. 1986-08-20. PMID:2941565. |
the inhibition of forskolin-stimulated adenylate cyclase activity by 5-hydroxytryptamine (5-ht) receptor agonists was measured in guinea pig and rat hippocampal membranes. |
1986-08-20 |
2023-08-11 |
rat |
| M De Vivo, S Maayan. Characterization of the 5-hydroxytryptamine1a receptor-mediated inhibition of forskolin-stimulated adenylate cyclase activity in guinea pig and rat hippocampal membranes. The Journal of pharmacology and experimental therapeutics. vol 238. issue 1. 1986-08-20. PMID:2941565. |
in guinea pig hippocampal membranes 8-hydroxy-2-(di-n-propylamino)tetralin, d-lysergic acid diethylamide, 5-ht and buspirone were potent in inhibiting forskolin-stimulated adenylate cyclase activity, with ec50 values of 18, 24, 53 and 146 nm, respectively. |
1986-08-20 |
2023-08-11 |
rat |
| M De Vivo, S Maayan. Characterization of the 5-hydroxytryptamine1a receptor-mediated inhibition of forskolin-stimulated adenylate cyclase activity in guinea pig and rat hippocampal membranes. The Journal of pharmacology and experimental therapeutics. vol 238. issue 1. 1986-08-20. PMID:2941565. |
in rat hippocampal membranes, 8-hydroxy-2-(di-n-propylamino)tetralin, d-lysergic acid diethylamide, 5-ht and buspirone were potent agonists and exhibited the same rank order of potency as in guinea pig hippocampal membranes. |
1986-08-20 |
2023-08-11 |
rat |
| C H Vanderwolf, G B Bake. Evidence that serotonin mediates non-cholinergic neocortical low voltage fast activity, non-cholinergic hippocampal rhythmical slow activity and contributes to intelligent behavior. Brain research. vol 374. issue 2. 1986-08-05. PMID:2941111. |
evidence that serotonin mediates non-cholinergic neocortical low voltage fast activity, non-cholinergic hippocampal rhythmical slow activity and contributes to intelligent behavior. |
1986-08-05 |
2023-08-11 |
human |
| D A Peter. Prenatal stress: effect on development of rat brain serotonergic neurons. Pharmacology, biochemistry, and behavior. vol 24. issue 5. 1986-08-04. PMID:3725840. |
[3h]5-ht binding was increased in cerebral cortex, decreased in hippocampus and unchanged in pons medulla while [3h]spiperone binding was increased in all three regions at 60 days of age. |
1986-08-04 |
2023-08-11 |
rat |
| D A Peter. Prenatal stress: effect on development of rat brain serotonergic neurons. Pharmacology, biochemistry, and behavior. vol 24. issue 5. 1986-08-04. PMID:3725840. |
prenatal stress reduced the rate of [14c]5-ht synthesis in hippocampus but not in cortex or pons medulla. |
1986-08-04 |
2023-08-11 |
rat |
| F C Zhou, E C Azmiti. Induced homotypic sprouting of serotonergic fibers in hippocampus. II. An immunocytochemistry study. Brain research. vol 373. issue 1-2. 1986-07-25. PMID:3013362. |
the dorsal hippocampus of the rat normally receives its 5-ht innervation from two homologous groups of cells in the median raphe nucleus via the cingulum bundle-induseum griseum (cb-ig) and the fornix-fimbria (ff) (j. comp. |
1986-07-25 |
2023-08-11 |
rat |
| F C Zhou, E C Azmiti. Induced homotypic sprouting of serotonergic fibers in hippocampus. II. An immunocytochemistry study. Brain research. vol 373. issue 1-2. 1986-07-25. PMID:3013362. |
5-ht immunoreactive (ir) fibers are distributed in a laminar pattern in the hippocampus. |
1986-07-25 |
2023-08-11 |
rat |
| S I Harik, S Yoshida, R Busto, M D Ginsber. Monoamine neurotransmitters in diffuse reversible forebrain ischemia and early recirculation: increased dopaminergic activity. Neurology. vol 36. issue 7. 1986-07-23. PMID:2872620. |
norepinephrine and serotonin decreased in the cerebral cortex and hippocampus during ischemia and diminished further during recirculation. |
1986-07-23 |
2023-08-11 |
rat |
| R F Seegal, K O Brosch, B Bus. Regional alterations in serotonin metabolism induced by oral exposure of rats to polychlorinated biphenyls. Neurotoxicology. vol 7. issue 1. 1986-07-14. PMID:2423934. |
total pcb concentrations and concentrations of serotonin and its major central metabolite, 5-hydroxyindoleacetic acid, were determined in the dorsal frontal cortex, lateral olfactory tract, hippocampus, medial-basal hypothalamus and brainstem. |
1986-07-14 |
2023-08-11 |
rat |
| R F Seegal, K O Brosch, B Bus. Regional alterations in serotonin metabolism induced by oral exposure of rats to polychlorinated biphenyls. Neurotoxicology. vol 7. issue 1. 1986-07-14. PMID:2423934. |
serotonin concentrations were reduced in frontal cortex and hippocampus, unaffected in hypothalamus and brainstem and elevated in lateral olfactory tract. |
1986-07-14 |
2023-08-11 |
rat |
| P M Hudson, H A Tilson, P H Chen, J S Hon. Neurobehavioral effects of permethrin are associated with alterations in regional levels of biogenic amine metabolites and amino acid neurotransmitters. Neurotoxicology. vol 7. issue 1. 1986-07-14. PMID:2872638. |
neurochemical analyses of regional biogenic amines and their metabolites and amino acids 5 hrs after 90 or 180 mg/kg indicated that 5-hiaa levels were increased in the hypothalamus (hyp), brain stem (bs), hippocampus (hpc), and striatum (str); 5-ht was not affected. |
1986-07-14 |
2023-08-11 |
rat |
| M Orosco, J H Trouvin, Y Cohen, C Jacquo. Ontogeny of brain monoamines in lean and obese female Zucker rats. Physiology & behavior. vol 36. issue 5. 1986-07-02. PMID:2424037. |
at 16 weeks, increases of da and 5-ht in the hypothalamus and decreases of norepinephrine (ne), 5-ht and 5-hiaa in the hippocampus appeared. |
1986-07-02 |
2023-08-11 |
rat |
| G G Gasanov, E M Melikov, G D Movsumo. [Comparison of the effect of serotonin administered into the dorsal hippocampus on conditioned passive and active avoidance in rats]. Biulleten' eksperimental'noi biologii i meditsiny. vol 101. issue 5. 1986-07-02. PMID:3708128. |
[comparison of the effect of serotonin administered into the dorsal hippocampus on conditioned passive and active avoidance in rats]. |
1986-07-02 |
2023-08-11 |
rat |
| T Nishikawa, B Scatto. Neuroanatomical site of the inhibitory influence of anxiolytic drugs on central serotonergic transmission. Brain research. vol 371. issue 1. 1986-06-30. PMID:2871894. |
systemic administration of diazepam (3 mg/kg s.c.) or flunitrazepam (1 mg/kg, s.c.) caused a reduction of 5-ht synthesis (as measured by the accumulation of 5-hydroxytryptophan after inhibition of aromatic amino acid decarboxylase) in the hippocampus but not in the cerebral cortex, striatum, cerebellum or spinal cord of the rat. |
1986-06-30 |
2023-08-11 |
rat |
| T Nishikawa, B Scatto. Neuroanatomical site of the inhibitory influence of anxiolytic drugs on central serotonergic transmission. Brain research. vol 371. issue 1. 1986-06-30. PMID:2871894. |
the decrease of hippocampal 5-ht synthesis induced by diazepam (5 mg/kg, s.c.) was antagonized by the benzodiazepine antagonist ro 15-1788 (2 x 30 mg/kg, s.c.) but not by bicuculline (2 x 1 mg/kg, s.c.). |
1986-06-30 |
2023-08-11 |
rat |