| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Mennini, M Gobbi, F Ponzio, S Garattin. Neurochemical effects of buspirone in rat hippocampus: evidence for selective activation of 5HT neurons. Archives internationales de pharmacodynamie et de therapie. vol 279. issue 1. 1986-05-22. PMID:2421657. |
the in vitro and in vivo data suggest that buspirone specifically activates 5ht neurons in hippocampus, and are compared with those obtained with diazepam. |
1986-05-22 |
2023-08-11 |
rat |
| W E Heydorn, G J Creed, K Q Nguyen, D M Jacobowit. Effect of 5,7-dihydroxytryptamine on the concentration of individual proteins in different areas of the rat brain. Brain research. vol 368. issue 1. 1986-05-22. PMID:3006866. |
reduction in central serotonin levels produced a decrease in the concentration of 3 different proteins (2 in the parietal cortex, 1 in the hippocampus). |
1986-05-22 |
2023-08-11 |
rat |
| W E Heydorn, G J Creed, K Q Nguyen, D M Jacobowit. Effect of 5,7-dihydroxytryptamine on the concentration of individual proteins in different areas of the rat brain. Brain research. vol 368. issue 1. 1986-05-22. PMID:3006866. |
two proteins, both in the hippocampus, were elevated in concentration following serotonin depletion. |
1986-05-22 |
2023-08-11 |
rat |
| D Wirtshafter, K E Asin, S A Loren. Serotonin-immunoreactive projections to the hippocampus from the interpeduncular nucleus in the rat. Neuroscience letters. vol 64. issue 3. 1986-05-15. PMID:2421209. |
about one third of the cells in the apical subnucleus of the ipn which projected to the hippocampus could be shown to contain serotonin immunoreactivity, whereas double-labeled cells were only rarely encountered in the lateral subnuclei. |
1986-05-15 |
2023-08-11 |
rat |
| M K Stachowiak, E M Stricker, J H Jacoby, M J Zigmon. Increased tryptophan hydroxylase activity in serotonergic nerve terminals spared by 5,7-dihydroxytryptamine. Biochemical pharmacology. vol 35. issue 8. 1986-05-14. PMID:2421731. |
when the animals were killed 3 or 21 days later, we observed a marked decrease in 5-ht content in septum and hippocampus and a parallel decline in in vitro high affinity 5-ht uptake. |
1986-05-14 |
2023-08-11 |
rat |
| J H Pirch, M J Corbus, G C Rigdon, W H Lynes. Generation of cortical event-related slow potentials in the rat involves nucleus basalis cholinergic innervation. Electroencephalography and clinical neurophysiology. vol 63. issue 5. 1986-05-12. PMID:2420562. |
the following bilateral measurements were obtained lesion studies: choline acetyltransferase (chat) in cortex and hippocampus; serotonin in cortex, hippocampus, striatum and nucleus accumbens; norepinephrine in cortex and hippocampus; dopamine in striatum and nucleus accumbens; and metabolites of serotonin, norepinephrine and dopamine in these areas. |
1986-05-12 |
2023-08-11 |
rat |
| G B Freeman, P Nielsen, G E Gibso. Automated method to estimate catecholamine and indoleamine content and turnover rates. Journal of chromatography. vol 374. issue 2. 1986-04-28. PMID:3958084. |
a double-label isotopic method for estimation of the rate of formation of serotonin (5-ht) and dopamine (da) in mouse striatum, hippocampus and cortex was standardized. |
1986-04-28 |
2023-08-11 |
mouse |
| G B Freeman, P Nielsen, G E Gibso. Automated method to estimate catecholamine and indoleamine content and turnover rates. Journal of chromatography. vol 374. issue 2. 1986-04-28. PMID:3958084. |
conversion of [3h]tyr to [3h]da was nearly ten times greater in striatum than cortex, whereas the formation of [3h]5-ht from [3h]trp was similar in striatum, cortex and hippocampus. |
1986-04-28 |
2023-08-11 |
mouse |
| K J Lookingland, D S Chapin, D W McKay, K E Moor. Comparative effects of the neurotoxins N-chloroethyl-N-ethyl-2-bromobenzylamine hydrochloride (DSP4) and 6-hydroxydopamine on hypothalamic noradrenergic, dopaminergic and 5-hydroxytryptaminergic neurons in the male rat. Brain research. vol 365. issue 2. 1986-04-11. PMID:2868785. |
), alone and in combination, were compared for their abilities to alter the concentrations of norepinephrine (ne), dopamine (da), dihydroxyphenylacetic acid (dopac) and 5-hydroxytryptamine (5-ht) in selected hypothalamic and extra-hypothalamic (striatum, frontal cortex, hippocampus) regions of the male rat brain. |
1986-04-11 |
2023-08-11 |
rat |
| M Devivo, S Maayan. Inhibition of forskolin-stimulated adenylate cyclase activity by 5-HT receptor agonists. European journal of pharmacology. vol 119. issue 3. 1986-04-03. PMID:2936612. |
we measured the inhibition of forskolin-stimulated adenylate cyclase activity in guinea pig hippocampal membranes by 5-ht, 5-carboxamidotryptamine (cat) and 8-hydroxy-2-(di-n-propylamino) tetralin (pat). |
1986-04-03 |
2023-08-11 |
cat |
| M R Pranzatelli, G Rubin, S R Snodgras. Serotonin-lesion myoclonic syndromes. I. Neurochemical profile and S-1 receptor binding. Brain research. vol 364. issue 1. 1986-04-03. PMID:3484992. |
multiple dht injections caused a 90-100% depletion of 5-ht concurrently in neocortex, hippocampus, striatum, septum/accumbens, pons, cerebellum, and cervical cord. |
1986-04-03 |
2023-08-11 |
rat |
| P F Gately, D S Segal, M A Geye. The behavioral effects of depletions of brain serotonin induced by 5,7-dihydroxytryptamine vary with time after administration. Behavioral and neural biology. vol 45. issue 1. 1986-04-02. PMID:3954713. |
liquid chromatographic assays revealed that this treatment did not significantly alter catecholamine levels but depleted hippocampal 5ht by 92% and striatal 5ht by 45%. |
1986-04-02 |
2023-08-11 |
rat |
| R Markstei. Hydergine: interaction with the neurotransmitter systems in the central nervous system. Journal de pharmacologie. vol 16 Suppl 3. 1986-03-31. PMID:2869188. |
hydergine had also mixed agonist/antagonist properties at the serotonin-sensitive adenylate cyclase in the rat hippocampus and the presynaptic serotonin autoreceptors present on nerve terminals in the rat cortex. |
1986-03-31 |
2023-08-11 |
rat |
| J H Trouvin, M Prioux-Guyonneau, Y Cohen, C Jacquo. Rat brain monoamine metabolism and hypobaric hypoxia: a new approach. General pharmacology. vol 17. issue 1. 1986-03-31. PMID:3949151. |
a chromatographic method with electrochemical detection was used to measure noradrenaline (na), dopamine (da), and serotonin (5-ht), 3,4-dihydroxyphenylacetic acid (dopac), homovanillic acid (hva), 3-methoxytyramine (3-mt) and 5-hydroxyindoleacetic acid (5-hiaa) in several brain areas (hypothalamus, hippocampus, striatum and rest of the brain) of rats exposed to a 7000 m simulated altitude for 3 hr. |
1986-03-31 |
2023-08-11 |
rat |
| W Felińska, R Szkilnik, B Stanosek, M Kamiński, K Ludyga, R Bru. [Effect of chronic exposure to nitrogen dioxide on biogenic amine levels in the brain of guinea pigs]. Medycyna pracy. vol 36. issue 4. 1986-03-14. PMID:2418330. |
the tissues were kept for 2-3 days at -20 degrees c, and afterwards the content of noradrenaline, 5-hydroxytryptamine and 5-hydroxyindole-acetic acid was estimated spectrofluorometrically in examined parts of the brain (thalamus--hypothalamus pons + medulla oblongata hippocampus, cortex frontalis). |
1986-03-14 |
2023-08-11 |
Not clear |
| F Owen, D R Chambers, S J Cooper, T J Crow, J A Johnson, R Lofthouse, M Poulte. Serotonergic mechanisms in brains of suicide victims. Brain research. vol 362. issue 1. 1986-02-24. PMID:2417665. |
the concentrations of 5-hydroxytryptamine (serotonin; 5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) were determined in occipital cortex and hippocampus and the high-affinity binding of ligands to the 5-ht1, 5-ht2 and imipramine-binding sites was assessed in frontal cortex, occipital cortex and hippocampus. |
1986-02-24 |
2023-08-11 |
Not clear |
| S Auerbach, F Zhou, B L Jacobs, E Azmiti. Serotonin turnover in raphe neurons transplanted into rat hippocampus. Neuroscience letters. vol 61. issue 1-2. 1986-02-18. PMID:2417169. |
serotonin turnover in raphe neurons transplanted into rat hippocampus. |
1986-02-18 |
2023-08-11 |
rat |
| S Auerbach, F Zhou, B L Jacobs, E Azmiti. Serotonin turnover in raphe neurons transplanted into rat hippocampus. Neuroscience letters. vol 61. issue 1-2. 1986-02-18. PMID:2417169. |
injections of the neurotoxin, 5,7-dihydroxytryptamine, into rostral raphe nuclei in rats reduced serotonin (5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) in hippocampus to 35-50% of normal levels but only reduced 5-ht synthesis and catabolism by 20-35%. |
1986-02-18 |
2023-08-11 |
rat |
| S Auerbach, F Zhou, B L Jacobs, E Azmiti. Serotonin turnover in raphe neurons transplanted into rat hippocampus. Neuroscience letters. vol 61. issue 1-2. 1986-02-18. PMID:2417169. |
transplantation of rat fetal raphe cells into the 5-ht-denervated hippocampus restored 5-ht and 5-hiaa levels and 5-ht synthesis to 125-150% of normal. |
1986-02-18 |
2023-08-11 |
rat |
| S Auerbach, F Zhou, B L Jacobs, E Azmiti. Serotonin turnover in raphe neurons transplanted into rat hippocampus. Neuroscience letters. vol 61. issue 1-2. 1986-02-18. PMID:2417169. |
this demonstrates that transplantation of fetal raphe tissue can restore metabolism to normal levels in the 5-ht denervated hippocampus. |
1986-02-18 |
2023-08-11 |
rat |