| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F Farabollini, L Lodi, C Lup. Interaction of tonic immobility and dexamethasone in the modulation of hippocampal 5-HT activity in rabbits. Pharmacology, biochemistry, and behavior. vol 25. issue 4. 1987-01-13. PMID:2431417. |
in order to investigate the relationship between adrenocortical function, brain 5-ht activity and immobility response in rabbits, the susceptibility to the reaction and 5-ht and 5-hiaa levels in the hippocampus were studied in animals whose pituitary-adrenal function was altered by chronic dex treatment. |
1987-01-13 |
2023-08-11 |
rabbit |
| M B Speisky, H Kalan. Vasopressin-like peptides retain ethanol tolerance in the absence of changes in serotonin synthesis in limbic structures. Pharmacology, biochemistry, and behavior. vol 25. issue 4. 1987-01-13. PMID:2431418. |
while the mechanism underlying this effect is unknown, we have reported that specific depletion of hippocampal serotonin (5-ht) prevents the prolongation of tolerance by dgavp. |
1987-01-13 |
2023-08-11 |
rat |
| M B Speisky, H Kalan. Vasopressin-like peptides retain ethanol tolerance in the absence of changes in serotonin synthesis in limbic structures. Pharmacology, biochemistry, and behavior. vol 25. issue 4. 1987-01-13. PMID:2431418. |
the present study explored possible presynaptic interactions between dgavp and 5-ht terminals in the hippocampus, in relation to tolerance retention. |
1987-01-13 |
2023-08-11 |
rat |
| M B Speisky, H Kalan. Vasopressin-like peptides retain ethanol tolerance in the absence of changes in serotonin synthesis in limbic structures. Pharmacology, biochemistry, and behavior. vol 25. issue 4. 1987-01-13. PMID:2431418. |
when administered acutely, dgavp had no effect on the rates of hippocampal or septal 5-ht synthesis in naive rats, as assessed by the nsd 1015 method. |
1987-01-13 |
2023-08-11 |
rat |
| M B Speisky, H Kalan. Vasopressin-like peptides retain ethanol tolerance in the absence of changes in serotonin synthesis in limbic structures. Pharmacology, biochemistry, and behavior. vol 25. issue 4. 1987-01-13. PMID:2431418. |
moreover, chronic dgavp treatment that maintained tolerance did not change the in vivo rate of 5-ht synthesis in the hippocampus or septum. |
1987-01-13 |
2023-08-11 |
rat |
| M B Speisky, H Kalan. Vasopressin-like peptides retain ethanol tolerance in the absence of changes in serotonin synthesis in limbic structures. Pharmacology, biochemistry, and behavior. vol 25. issue 4. 1987-01-13. PMID:2431418. |
similarly, no significant differences were found in the levels of hippocampal 5-ht or 5-hiaa. |
1987-01-13 |
2023-08-11 |
rat |
| M B Speisky, H Kalan. Vasopressin-like peptides retain ethanol tolerance in the absence of changes in serotonin synthesis in limbic structures. Pharmacology, biochemistry, and behavior. vol 25. issue 4. 1987-01-13. PMID:2431418. |
in vitro studies revealed, on the other hand, that addition of avp to the incubation medium failed to affect the spontaneous and stimulated release of endogenous 5-ht from hippocampal slices. |
1987-01-13 |
2023-08-11 |
rat |
| M B Speisky, H Kalan. Vasopressin-like peptides retain ethanol tolerance in the absence of changes in serotonin synthesis in limbic structures. Pharmacology, biochemistry, and behavior. vol 25. issue 4. 1987-01-13. PMID:2431418. |
while the lack of changes in hippocampal 5-ht synthesis argues against a presynaptic dgavp-5-ht interaction, the possibility remains of a peptide modulation of 5-ht postsynaptic actions. |
1987-01-13 |
2023-08-11 |
rat |
| D J Mokler, K W Stoudt, L C Sherman, R H Rec. The effects of intracranial administration of hallucinogens on operant behavior in the rat. I. Lysergic acid diethylamide. Pharmacology, biochemistry, and behavior. vol 25. issue 4. 1987-01-13. PMID:3538062. |
the sites were chosen as major areas of the brain 5-hydroxytryptamine (5ht) system: the dorsal and median raphe nuclei, dorsal hippocampus, lateral habenular nuclei, and the prefrontal cortex. |
1987-01-13 |
2023-08-11 |
rat |
| A Colino, J V Halliwel. 8-OH-DPAT is a strong antagonist of 5-HT action in rat hippocampus. European journal of pharmacology. vol 130. issue 1-2. 1987-01-06. PMID:2946594. |
8-oh-dpat is a strong antagonist of 5-ht action in rat hippocampus. |
1987-01-06 |
2023-08-11 |
rat |
| A Basse-Tomusk, G V Rebe. Ipsapirone depresses neuronal activity in the dorsal raphe nucleus and the hippocampal formation. European journal of pharmacology. vol 130. issue 1-2. 1987-01-06. PMID:3780856. |
in the hippocampus, dentate granule cells matched the responsiveness of dorsal raphe serotonin neurons, the median effective dose for 50% inhibition being 125.0 micrograms/kg in both areas. |
1987-01-06 |
2023-08-11 |
rat |
| R Andrade, R C Malenka, R A Nicol. A G protein couples serotonin and GABAB receptors to the same channels in hippocampus. Science (New York, N.Y.). vol 234. issue 4781. 1986-12-18. PMID:2430334. |
a g protein couples serotonin and gabab receptors to the same channels in hippocampus. |
1986-12-18 |
2023-08-11 |
Not clear |
| R Markstein, D Hoyer, G Enge. 5-HT1A-receptors mediate stimulation of adenylate cyclase in rat hippocampus. Naunyn-Schmiedeberg's archives of pharmacology. vol 333. issue 4. 1986-12-12. PMID:2945992. |
serotonin (5-ht) stimulated adenylate cyclase activity in homogenates of rat hippocampus. |
1986-12-12 |
2023-08-11 |
rat |
| R Markstein, D Hoyer, G Enge. 5-HT1A-receptors mediate stimulation of adenylate cyclase in rat hippocampus. Naunyn-Schmiedeberg's archives of pharmacology. vol 333. issue 4. 1986-12-12. PMID:2945992. |
the rank order of potency of 13 agonists stimulating adenylate cyclase activity in homogenates of rat hippocampus was in good agreement with the rank order of affinity of these agonists for the 5-ht1a binding site: n,n-dipropyl-5-carboxamidotryptamine (dp-5-ct) greater than 5-carboxamidotryptamine (5-ct) greater than 8-oh-dpat greater than 5-ht greater than 5-methoxytryptamine (5-och3t) greater than d-lsd greater than 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1h-indole (ru 24969) greater than alpha-methylserotonin (alpha-ch3-5-ht) greater than dopamine greater than 2-methylserotonin (2-ch3-5-ht). |
1986-12-12 |
2023-08-11 |
rat |
| H K Kimelberg, D M Kat. Regional differences in 5-hydroxytryptamine and catecholamine uptake in primary astrocyte cultures. Journal of neurochemistry. vol 47. issue 5. 1986-11-19. PMID:3531407. |
the uptake of 3h-labelled 5-hydroxytryptamine (5-ht, serotonin) norepinephrine ([3h]ne), and 3,4-dihydroxyphenylethylamine ([ 3h]dopamine, [3h]da) was studied in primary astrocyte cultures prepared from the cerebral cortex, corpus striatum, and hippocampal regions of neonatal rat brain. |
1986-11-19 |
2023-08-11 |
rat |
| H K Kimelberg, D M Kat. Regional differences in 5-hydroxytryptamine and catecholamine uptake in primary astrocyte cultures. Journal of neurochemistry. vol 47. issue 5. 1986-11-19. PMID:3531407. |
for [3h]5-ht the magnitude of uptake was corpus striatum greater than or equal to cerebral cortex greater than hippocampus, whereas for [3h]ne the order was hippocampus greater than corpus striatum greater than cerebral cortex. |
1986-11-19 |
2023-08-11 |
rat |
| J M Palacios, R Markstein, A Pazo. Serotonin-1C sites in the choroid plexus are not linked in a stimulatory or inhibitory way to adenylate cyclase. Brain research. vol 380. issue 1. 1986-11-13. PMID:3019464. |
the binding of [3h]serotonin to choroid plexus membranes was also unaffected by gppnhp while a dose-dependent decrease was observed in pig cortical and hippocampal membranes. |
1986-11-13 |
2023-08-11 |
rat |
| J M Palacios, R Markstein, A Pazo. Serotonin-1C sites in the choroid plexus are not linked in a stimulatory or inhibitory way to adenylate cyclase. Brain research. vol 380. issue 1. 1986-11-13. PMID:3019464. |
while forskolin-stimulated adenylate cyclase in the rat hippocampus was inhibited by serotonin forskolin-stimulated adenylate cyclase in the choroid plexus was insensitive to serotonin. |
1986-11-13 |
2023-08-11 |
rat |
| M B Emerit, H Gozlan, A Marquet, M Hamo. Irreversible blockade of central 5-HT1A receptor binding sites by the photoaffinity probe 8-methoxy-3'-NAP-amino-PAT. European journal of pharmacology. vol 127. issue 1-2. 1986-11-10. PMID:2944752. |
in the dark, this compound, 8-methoxy-2-(n-n-propyl,n-3-(2-nitro-4-azidophenyl)aminopropyl) aminotetralin or 8-methoxy-3'-nap-amino-pat, displaced [3h]8-oh-dpat and [3h]5-ht bound to 5-ht1a and 5-ht1 sites in hippocampal membranes with ic50 values of 6.6 and 18.1 nm respectively. |
1986-11-10 |
2023-08-11 |
rat |
| A V Juorio, A J Greenshaw, A A Boulto. Effects of acute and chronic phenelzine on regional monoamine metabolism in rats and its potentiation by deuterium substitution. Naunyn-Schmiedeberg's archives of pharmacology. vol 333. issue 3. 1986-10-30. PMID:2429193. |
the following brain regions and compounds were assessed using high performance liquid chromatography with electrochemical detection: striatum: dopamine, dopac, hva, 5-ht, 5-hiaa; hypothalamus: dopamine, 5-ht, 5-hiaa, noradrenaline; hippocampus: 5-ht, 5-hiaa, noradrenaline; frontal cortex: dopamine, noradrenaline, 5-ht, 5-hiaa. |
1986-10-30 |
2023-08-11 |
rat |