| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J O Marcusson, D G Morgan, B Winblad, C E Finc. Serotonin-2 binding sites in human frontal cortex and hippocampus. Selective loss of S-2A sites with age. Brain research. vol 311. issue 1. 1984-12-19. PMID:6488044. |
serotonin (s-2) binding sites were characterized in human frontal cortex and hippocampus throughout the lifespan. |
1984-12-19 |
2023-08-12 |
human |
| H Hallman, E Sundström, G Jonsso. Effects of the noradrenaline neurotoxin DSP 4 on monoamine neurons and their transmitter turnover in rat CNS. Journal of neural transmission. vol 60. issue 2. 1984-12-12. PMID:6208323. |
5-hydroxytryptamine levels were generally unaltered after dsp 4, except for an about 10-25% reduction in cerebral cortex and hippocampus. |
1984-12-12 |
2023-08-12 |
rat |
| T Kádár, M Várszegi, S K Sudakov, B Penke, G Telegd. Changes in brain monoamine levels of rats during cholecystokinin octapeptide-induced suppression of feeding. Pharmacology, biochemistry, and behavior. vol 21. issue 3. 1984-12-11. PMID:6093149. |
cholecystokinin octapeptide (cck-8) in doses of 5 or 10 micrograms/kg was injected intraperitoneally to 24 hr food-deprived rats before a 30 min feeding period, and the dopamine (da), norepinephrine (ne) and 5-hydroxytryptamine (5-ht) contents of the hypothalamus, mesencephalon, amygdala, hippocampus and striatum were measured thereafter. |
1984-12-11 |
2023-08-12 |
rat |
| A Janowsky, R Labarca, S M Pau. Characterization of neurotransmitter receptor-mediated phosphatidylinositol hydrolysis in the rat hippocampus. Life sciences. vol 35. issue 19. 1984-12-05. PMID:6092808. |
the hydrolysis of phosphatidylinositol in hippocampal slices is induced by carbachol, serotonin, norepinephrine and phenylephrine. |
1984-12-05 |
2023-08-12 |
rat |
| A Janowsky, R Labarca, S M Pau. Characterization of neurotransmitter receptor-mediated phosphatidylinositol hydrolysis in the rat hippocampus. Life sciences. vol 35. issue 19. 1984-12-05. PMID:6092808. |
the concentration response curve for serotonin-induced phosphatidylinositol hydrolysis is bimodal and the effect is blocked by metergoline, but not mianserin, indicating that the effect of serotonin in the hippocampus may be mediated by 5ht1 receptors. |
1984-12-05 |
2023-08-12 |
rat |
| J Traber, M A Davies, W U Dompert, T Glaser, T Schuurman, P R Seide. Brain serotonin receptors as a target for the putative anxiolytic TVX Q 7821. Brain research bulletin. vol 12. issue 6. 1984-11-19. PMID:6541079. |
the high affinity, specific binding of 3h-tvx q 7821 to calf hippocampal membranes was displaced by serotonin (5-ht) but not by diazepam. |
1984-11-19 |
2023-08-12 |
Not clear |
| E H Lee, M A Geye. Dopamine autoreceptor mediation of the effects of apomorphine on serotonin neurons. Pharmacology, biochemistry, and behavior. vol 21. issue 2. 1984-11-15. PMID:6207549. |
serotonin neurons in the median raphe and its projection site, the hippocampus, were unaffected. |
1984-11-15 |
2023-08-12 |
rat |
| M H Bassant, D Fage, J Dedek, F Cathala, L Court, B Scatto. Monoamine abnormalities in the brain of scrapie-infected rats. Brain research. vol 308. issue 1. 1984-11-14. PMID:6206919. |
scrapie-infected rats showed a reduction in the levels of serotonin (prefrontal cortex, hippocampus, striatum) and dopamine (striatum) and an elevation of 5-hiaa levels (cerebral cortex, striatum, thalamus). |
1984-11-14 |
2023-08-12 |
mouse |
| D L DeHaven, T J Walsh, R B Mailma. Effects of trimethyltin on dopaminergic and serotonergic function in the central nervous system. Toxicology and applied pharmacology. vol 75. issue 2. 1984-10-24. PMID:6206607. |
administration of 3 mg/kg tmt decreased the concentration of serotonin in striatum and nucleus accumbens, and increased the concentration of 5-hydroxyindoleacetic acid (5-hiaa) in hippocampus. |
1984-10-24 |
2023-08-12 |
rat |
| D L DeHaven, T J Walsh, R B Mailma. Effects of trimethyltin on dopaminergic and serotonergic function in the central nervous system. Toxicology and applied pharmacology. vol 75. issue 2. 1984-10-24. PMID:6206607. |
the 7-mg/kg dose resulted in increased concentrations of 5-hiaa in striatum, nucleus accumbens, septum, amygdala/pyriform cortex, and hippocampus, and also decreased the concentration of 5-ht only in amygdala/pyriform cortex. |
1984-10-24 |
2023-08-12 |
rat |
| C S Clewans, E Azmiti. Tryptophan hydroxylase in hippocampus and midbrain following unilateral injection of 5,7-dihydroxytryptamine. Brain research. vol 307. issue 1-2. 1984-10-19. PMID:6466991. |
we have previously shown using anatomical methods that partial denervation of the rat hippocampus by removal of serotonergic (5-ht) fibers in the cingulum bundle induces sprouting of intact 5-ht fibers reaching the hippocampus in the fornix-fimbria. |
1984-10-19 |
2023-08-12 |
rat |
| C S Clewans, E Azmiti. Tryptophan hydroxylase in hippocampus and midbrain following unilateral injection of 5,7-dihydroxytryptamine. Brain research. vol 307. issue 1-2. 1984-10-19. PMID:6466991. |
in midbrain, site of neuronal cell bodies of hippocampal 5-ht projections, enzyme activity gradually increased, reaching a maximum by 28 days after the lesion. |
1984-10-19 |
2023-08-12 |
rat |
| C S Clewans, E Azmiti. Tryptophan hydroxylase in hippocampus and midbrain following unilateral injection of 5,7-dihydroxytryptamine. Brain research. vol 307. issue 1-2. 1984-10-19. PMID:6466991. |
these results indicate that 5-ht fibers remaining in the hippocampus following partial denervation are able to compensate biochemically for those removed by cingulum bundle lesions. |
1984-10-19 |
2023-08-12 |
rat |
| R C Meibach, S G Beck, S Maayani, J P Gree. Regional differences in binding of [3H]LSD and [3H]5-HT in calf hippocampal slices revealed by radioautography and rapid filtration studies. Brain research. vol 307. issue 1-2. 1984-10-19. PMID:6467009. |
regional differences in binding of [3h]lsd and [3h]5-ht in calf hippocampal slices revealed by radioautography and rapid filtration studies. |
1984-10-19 |
2023-08-12 |
rat |
| R C Meibach, S G Beck, S Maayani, J P Gree. Regional differences in binding of [3H]LSD and [3H]5-HT in calf hippocampal slices revealed by radioautography and rapid filtration studies. Brain research. vol 307. issue 1-2. 1984-10-19. PMID:6467009. |
previous radioautographic experiments demonstrated that binding sites labeled by [3h]5-ht and [3h]lsd in rat brain were seen in all layers of ca1, ca4 and the dentate gyrus but not in fields ca2 and ca3 of the hippocampus. |
1984-10-19 |
2023-08-12 |
rat |
| G A Serri, D L El. A comparative study of aggression related changes in brain serotonin in CBA, C57BL, and DBA mice. Behavioural brain research. vol 12. issue 3. 1984-10-17. PMID:6540585. |
hippocampal (hpc) 5-ht was also lower in the more aggressive animals in cba mice. |
1984-10-17 |
2023-08-12 |
mouse |
| A L Ask, I Fagervall, M Jonze, D Kelder, R Nygren, S B Ros. Effects of acute and repeated administration of amiflamine on monoamine oxidase inhibition in the rat. Biochemical pharmacology. vol 33. issue 18. 1984-10-05. PMID:6477643. |
in the brain slices this inhibition corresponded to a decrease in the concentration of 5-hydroxyindoleacetic acid (5-hiaa) and to an increase in the concentration of 5-ht in the hypothalamus, the hippocampus and the striatum. |
1984-10-05 |
2023-08-12 |
rat |
| R J Bodnar, J H Kordower, A Reches, M M Wallace, S Fah. Reductions in pain thresholds and morphine analgesia following intracerebroventricular parachlorophenylalanine. Pharmacology, biochemistry, and behavior. vol 21. issue 1. 1984-09-19. PMID:6235525. |
the third and fourth experiments indicated that hippocampal and spinal levels of either serotonin or 5-hydroxyindoleacetic acid were not significantly affected by icv pcpa pretreatment. |
1984-09-19 |
2023-08-12 |
Not clear |
| R J Bodnar, J H Kordower, A Reches, M M Wallace, S Fah. Reductions in pain thresholds and morphine analgesia following intracerebroventricular parachlorophenylalanine. Pharmacology, biochemistry, and behavior. vol 21. issue 1. 1984-09-19. PMID:6235525. |
these data indicate that the hyperalgesia and morphine analgesia impairments noted following icv pcpa do not correspond with changes in serotonin from hippocampal or spinal tissue and such effects are discussed in terms of alternative modes of action. |
1984-09-19 |
2023-08-12 |
Not clear |
| V R Holets, C W Cotma. Postnatal development of the serotonin innervation of the hippocampus and dentate gyrus following raphe implants. The Journal of comparative neurology. vol 226. issue 4. 1984-09-19. PMID:6378990. |
postnatal development of the serotonin innervation of the hippocampus and dentate gyrus following raphe implants. |
1984-09-19 |
2023-08-12 |
rat |