| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D M Stone, G R Hanson, J W Gib. Differences in the central serotonergic effects of methylenedioxymethamphetamine (MDMA) in mice and rats. Neuropharmacology. vol 26. issue 11. 1988-03-09. PMID:2448703. |
whereas neostriatal concentrations of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in mouse were transiently decreased after a single moderately high dose of mdma (15 mg/kg), mouse neostriatal or hippocampal tryptophan hydroxylase activity was not significantly affected, even after a dose of 60 mg/kg. |
1988-03-09 |
2023-08-11 |
mouse |
| C T Fischette, B Nock, K Renne. Effects of 5,7-dihydroxytryptamine on serotonin1 and serotonin2 receptors throughout the rat central nervous system using quantitative autoradiography. Brain research. vol 421. issue 1-2. 1988-02-10. PMID:3690273. |
the results indicate that at least some of the 5-ht1 sites labelled by [3h]5-ht in the hippocampus and dorsal raphe nucleus are presynaptic, whereas 5-ht2 receptors are probably postsynaptic. |
1988-02-10 |
2023-08-11 |
rat |
| E Friedman, H Y Wan. Effect of chronic lithium treatment on 5-hydroxytryptamine autoreceptors and release of 5-[3H]hydroxytryptamine from rat brain cortical, hippocampal, and hypothalamic slices. Journal of neurochemistry. vol 50. issue 1. 1988-01-26. PMID:2826685. |
effect of chronic lithium treatment on 5-hydroxytryptamine autoreceptors and release of 5-[3h]hydroxytryptamine from rat brain cortical, hippocampal, and hypothalamic slices. |
1988-01-26 |
2023-08-11 |
rat |
| E Friedman, H Y Wan. Effect of chronic lithium treatment on 5-hydroxytryptamine autoreceptors and release of 5-[3H]hydroxytryptamine from rat brain cortical, hippocampal, and hypothalamic slices. Journal of neurochemistry. vol 50. issue 1. 1988-01-26. PMID:2826685. |
chronic lithium treatment was also found to be associated with a decrease in basal [3h]5-ht overflow in the cortex and hypothalamus but not in hippocampus [corrected]. |
1988-01-26 |
2023-08-11 |
rat |
| A L Vale, D J Balfou. The role of hippocampal 5-HT in the effects of nicotine on habituation to an X-maze. European journal of pharmacology. vol 141. issue 2. 1988-01-19. PMID:2445590. |
the role of hippocampal 5-ht in the effects of nicotine on habituation to an x-maze. |
1988-01-19 |
2023-08-11 |
rat |
| A L Vale, D J Balfou. The role of hippocampal 5-HT in the effects of nicotine on habituation to an X-maze. European journal of pharmacology. vol 141. issue 2. 1988-01-19. PMID:2445590. |
however, analysis of covariance indicated that reduced 5-hydroxytryptamine secretion in the hippocampus was probably not the mechanism by which nicotine stimulated total activity in these rats. |
1988-01-19 |
2023-08-11 |
rat |
| C Coudray-Lucas, A Le Guen, M Prioux-Guyonneau, Y Cohen, J Wepierr. Changes in brain monoamine content and metabolism induced by paraoxon and soman intoxication. Effect of atropine. Xenobiotica; the fate of foreign compounds in biological systems. vol 17. issue 9. 1988-01-19. PMID:3687068. |
soman induced a decrease in hypothalamic, hippocampal and cortical noradrenaline, an increase in hippocampal and cortical dopamine and an increase in hypothalamic serotonin while paraoxon did not modify these neurotransmitter concentrations. |
1988-01-19 |
2023-08-11 |
Not clear |
| D W Gietzen, Q R Rogers, P M Leung, B Semon, T Piechot. Serotonin and feeding responses of rats to amino acid imbalance: initial phase. The American journal of physiology. vol 253. issue 5 Pt 2. 1988-01-12. PMID:2446514. |
also measurements made in the absence of pharmacological treatment showed that the ratio 5-hydroxyindole acetic acid-to-serotonin, a putative index of serotonin turnover, was increased 155% in the raphe nuclei and 140% in the hippocampus 3.5 h after ingestion of the mild isoleucine-imbalanced diet. |
1988-01-12 |
2023-08-11 |
rat |
| D J Mokler, S E Robinson, J H Johnson, J S Hong, J A Rosecran. Neonatal administration of delta-9-tetrahydrocannabinol (THC) alters the neurochemical response to stress in the adult Fischer-344 rat. Neurotoxicology and teratology. vol 9. issue 4. 1988-01-11. PMID:2446111. |
levels of norepinephrine, dopamine and 5-hydroxytryptamine and metabolites were determined in frontal cortex, hippocampus and hypothalamus. |
1988-01-11 |
2023-08-11 |
rat |
| D J Mokler, S E Robinson, J H Johnson, J S Hong, J A Rosecran. Neonatal administration of delta-9-tetrahydrocannabinol (THC) alters the neurochemical response to stress in the adult Fischer-344 rat. Neurotoxicology and teratology. vol 9. issue 4. 1988-01-11. PMID:2446111. |
neonatal thc and stress elevated norepinephrine above control levels in the hypothalamus, while increasing 5ht in the hippocampus and frontal cortex. |
1988-01-11 |
2023-08-11 |
rat |
| A Ebel, M T Strosser, E Kemp. Genotypic differences in central neurotransmitter responses to aging in mice. Neurobiology of aging. vol 8. issue 5. 1988-01-11. PMID:2891055. |
dopamine, serotonin, cholinergic and somatostatin responses to aging have been followed in striatum and hippocampus of two inbred strains of mice (c57bl and balb/c). |
1988-01-11 |
2023-08-11 |
mouse |
| A Ebel, M T Strosser, E Kemp. Genotypic differences in central neurotransmitter responses to aging in mice. Neurobiology of aging. vol 8. issue 5. 1988-01-11. PMID:2891055. |
conversely, c57bl mice react to aging by increased serotonin turnover in hippocampus and decreased 5hiaa levels in both structures studied, whereas the balb/c strain remains unaffected. |
1988-01-11 |
2023-08-11 |
mouse |
| A Ebel, M T Strosser, E Kemp. Genotypic differences in central neurotransmitter responses to aging in mice. Neurobiology of aging. vol 8. issue 5. 1988-01-11. PMID:2891055. |
also, structure dependency is observed: in c57bl mice serotonin turnover appears to be unchanged in striatum and increased in hippocampus; in the balb/c the slowing down of dopamine activity in striatum is not observed in hippocampus. |
1988-01-11 |
2023-08-11 |
mouse |
| A Baskys, C E Niesen, P L Carle. Altered modulatory actions of serotonin on dentate granule cells of aged rats. Brain research. vol 419. issue 1-2. 1988-01-11. PMID:3676719. |
the effects of serotonin (5-ht) on dentate granule (dg) neurons in hippocampal slices taken from young mature (6-8 months) and old (25-29 months) rats were compared. |
1988-01-11 |
2023-08-11 |
rat |
| D J Mokler, K W Stoudt, L C Sherman, R H Rec. The effects of intracranial administration of hallucinogens on operant behavior in the rat. II. 2,5-Dimethoxy-4-methylamphetamine (DOM). Pharmacology, biochemistry, and behavior. vol 28. issue 3. 1988-01-11. PMID:3685066. |
sites were chosen as major areas of the brain 5-hydroxytryptamine (5-ht) system: the dorsal and median raphe nuclei, dorsal hippocampus, lateral habenular nuclei and the prefrontal cortex. |
1988-01-11 |
2023-08-11 |
rat |
| M Johnson, G R Hanson, J W Gib. Effects of N-ethyl-3,4-methylenedioxyamphetamine (MDE) on central serotonergic and dopaminergic systems of the rat. Biochemical pharmacology. vol 36. issue 23. 1987-12-29. PMID:2446629. |
mde (10 mg/kg) produced a significant decrease in the concentration of 5-hydroxytryptamine (5-ht) 1 hr later in the frontal cortex and the hippocampus without affecting the concentration of 5-hydroxyindoleacetic acid (5-hiaa) or tryptophan hydroxylase (tph) activity. |
1987-12-29 |
2023-08-11 |
rat |
| K F Martin, R Maso. Isapirone is a partial agonist at 5-hydroxytryptamine 1A (5-HT1A) receptors in the rat hippocampus: electrophysiological evidence. European journal of pharmacology. vol 141. issue 3. 1987-12-16. PMID:2889611. |
isapirone is a partial agonist at 5-hydroxytryptamine 1a (5-ht1a) receptors in the rat hippocampus: electrophysiological evidence. |
1987-12-16 |
2023-08-11 |
rat |
| K F Martin, R Maso. Isapirone is a partial agonist at 5-hydroxytryptamine 1A (5-HT1A) receptors in the rat hippocampus: electrophysiological evidence. European journal of pharmacology. vol 141. issue 3. 1987-12-16. PMID:2889611. |
using iontophoretic techniques we observed that in vivo isapirone (tvx q 7821), a selective ligand for the 5-ht1a binding site, at low ejection currents (5-30 na) antagonised 5-ht and 8-hydroxy-2-(di-n-propylamino) tetralin (dpat)-induced suppression of hippocampal unit activity, with little effect on baseline firing rate itself. |
1987-12-16 |
2023-08-11 |
rat |
| K F Martin, R Maso. Isapirone is a partial agonist at 5-hydroxytryptamine 1A (5-HT1A) receptors in the rat hippocampus: electrophysiological evidence. European journal of pharmacology. vol 141. issue 3. 1987-12-16. PMID:2889611. |
these data demonstrate that isapirone is a 5-ht1a receptor antagonist with partial agonist properties on 5-ht sensitive neurones in the rat hippocampus. |
1987-12-16 |
2023-08-11 |
rat |
| M D Diaz Palarea, M C Gonzalez, M Rodrigue. Behavioral lateralization in the T-maze and monoaminergic brain asymmetries. Physiology & behavior. vol 40. issue 6. 1987-12-15. PMID:3671548. |
there were no significant differences for serotonin or norepinephrine between the t-maze preferred and non-preferred brain sides in the s. nigra, ventral tegmental area, striatum, acumbens, frontal lobe or hippocampus. |
1987-12-15 |
2023-08-11 |
rat |