Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
L E Mello, Z A Bortolotto, E A Cavalheir. Brain indoleamines in alloxan- and streptozotocin-induced diabetic rats. Journal of neurochemistry. vol 51. issue 3. 1988-09-26. PMID:2970524. |
levels of brain indoleamines exhibited a strong positive correlation with wet-dog shakes (an index of 5-ht activity) elicited by hippocampal stimulation. |
1988-09-26 |
2023-08-11 |
rat |
J Sawynok, A Rei. Role of ascending and descending serotonergic pathways in the antinociceptive effect of baclofen. Naunyn-Schmiedeberg's archives of pharmacology. vol 337. issue 4. 1988-09-16. PMID:3405312. |
lesions to the nucleus raphe medianus produced a marked depletion of 5-ht in the hippocampus and produced the same effect on baclofen. |
1988-09-16 |
2023-08-11 |
rat |
F C Zhou, S B Auerbach, E C Azmiti. Transplanted raphe and hippocampal fetal neurons do not displace afferent inputs to the dorsal hippocampus from serotonergic neurons in the median raphe nucleus of the rat. Brain research. vol 450. issue 1-2. 1988-09-15. PMID:3401722. |
to determine if fetal transplants can substitute for or suppress intrinsic serotonergic (5-ht) innervation, we studied the relationship between transplanted and the endogenous raphe neurons projecting to the hippocampus. |
1988-09-15 |
2023-08-11 |
rat |
F C Zhou, S B Auerbach, E C Azmiti. Transplanted raphe and hippocampal fetal neurons do not displace afferent inputs to the dorsal hippocampus from serotonergic neurons in the median raphe nucleus of the rat. Brain research. vol 450. issue 1-2. 1988-09-15. PMID:3401722. |
fetal raphe transplants produced a 5-ht hyperinnervation of dorsal hippocampus in adult rats. |
1988-09-15 |
2023-08-11 |
rat |
F C Zhou, S B Auerbach, E C Azmiti. Transplanted raphe and hippocampal fetal neurons do not displace afferent inputs to the dorsal hippocampus from serotonergic neurons in the median raphe nucleus of the rat. Brain research. vol 450. issue 1-2. 1988-09-15. PMID:3401722. |
changes in the innervation pattern and 5-ht level in the dorsal hippocampus occur following transplantation of fetal tissue. |
1988-09-15 |
2023-08-11 |
rat |
W Slikker, S F Ali, A C Scallet, C H Frith, G D Newport, J R Baile. Neurochemical and neurohistological alterations in the rat and monkey produced by orally administered methylenedioxymethamphetamine (MDMA). Toxicology and applied pharmacology. vol 94. issue 3. 1988-09-02. PMID:2456631. |
brain regions including the hippocampus (h), caudate nucleus (cn), hypothalamus (hy), frontal cortex (fc), and brain stem (bs) were analyzed by hplc with electrochemical detection for concentrations of dopamine (da), dihydroxyphenylacetic acid (dopac), homovanillic acid (hva), serotonin (5-ht), 5-hydroxyindoleacetic acid (5-hiaa), and norepinephrine (ne). |
1988-09-02 |
2023-08-11 |
rat |
P Blier, Y Chaput, C de Montign. Long-term 5-HT reuptake blockade, but not monoamine oxidase inhibition, decreases the function of terminal 5-HT autoreceptors: an electrophysiological study in the rat brain. Naunyn-Schmiedeberg's archives of pharmacology. vol 337. issue 3. 1988-08-22. PMID:3260661. |
unitary extracellular recordings were obtained from ca3 dorsal hippocampus pyramidal neurons under chloral hydrate anesthesia in rats treated daily with fluoxetine (10 mg/kg/day x 14 days), a selective 5-ht reuptake blocker, or clorgyline (1 mg/kg/day x 21 days), an inhibitor of type a monoamine oxidase. |
1988-08-22 |
2023-08-11 |
rat |
P Blier, Y Chaput, C de Montign. Long-term 5-HT reuptake blockade, but not monoamine oxidase inhibition, decreases the function of terminal 5-HT autoreceptors: an electrophysiological study in the rat brain. Naunyn-Schmiedeberg's archives of pharmacology. vol 337. issue 3. 1988-08-22. PMID:3260661. |
the function of the terminal 5-ht autoreceptors was assessed by comparing the effectiveness of the electrical stimulation of the ascending 5-ht pathway on the firing activity of hippocampus pyramidal neurons prior to, and following, the administration of methiothepin, an antagonist of the terminal 5-ht autoreceptor, and, by determining the ratio of effectiveness of 0.8 hz (s1) and 5 hz (s2) stimulations. |
1988-08-22 |
2023-08-11 |
rat |
J C Soto, E J Marc. Measurement of 5-hydroxytryptamine turnover rate in rat cerebral arteries. The Journal of pharmacy and pharmacology. vol 40. issue 3. 1988-08-18. PMID:2455784. |
in the hippocampus, pargyline induced a lineal accumulation of 5-ht throughout the experiment as well as an exponential decay of the 5-hiaa concentration. |
1988-08-18 |
2023-08-11 |
rat |
M Beni, D E Pellegrini-Giampietro, F Moron. A new endogenous anxiolytic agent: L-pyroglutamic acid. Fundamental & clinical pharmacology. vol 2. issue 2. 1988-08-17. PMID:2455680. |
furthermore, anxiolytic doses of the amino acid did not change the content of 5-hydroxytryptamine (5-ht) or of 5-hydroxyindoleacetic acid (5-hiaa) in the rat cortex and hippocampus. |
1988-08-17 |
2023-08-11 |
rat |
Y Chaput, C de Montign. Effects of the 5-hydroxytryptamine receptor antagonist, BMY 7378, on 5-hydroxytryptamine neurotransmission: electrophysiological studies in the rat central nervous system. The Journal of pharmacology and experimental therapeutics. vol 246. issue 1. 1988-08-17. PMID:2839669. |
in the present electrophysiological studies, the effects of the putative 5-hydroxytryptamine (5-ht) receptor antagonist, bmy 7378, on the response of dorsal raphe nucleus 5-ht neurons and of ca3 dorsal hippocampus pyramidal neurons to 5-ht and 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat) were investigated in chloral hydrate-anesthetized rats. |
1988-08-17 |
2023-08-11 |
rat |
Y Chaput, C de Montign. Effects of the 5-hydroxytryptamine receptor antagonist, BMY 7378, on 5-hydroxytryptamine neurotransmission: electrophysiological studies in the rat central nervous system. The Journal of pharmacology and experimental therapeutics. vol 246. issue 1. 1988-08-17. PMID:2839669. |
bmy 7378 reduced the effectiveness of 8-oh-dpat, but not that of 5-ht, in depressing 5-ht neuron firing rate, whereas that of both agonists was reduced by concurrent application of bmy 7378 in the hippocampus. |
1988-08-17 |
2023-08-11 |
rat |
M R Pranzatelli, A Dailey, S Markus. The regulation of TRH and serotonin receptors: chronic TRH and analog administration in the rat. Journal of receptor research. vol 8. issue 5. 1988-08-17. PMID:2839679. |
5-ht and ne concentrations measured by hplc were not altered in brainstem or hippocampus. |
1988-08-17 |
2023-08-11 |
rat |
G A Foster, M Schultzberg, F H Gage, A Björklund, T Hökfelt, A C Cuello, A A Verhofstad, T J Visser, P C Emso. Transmitter expression and morphological development of embryonic medullary and mesencephalic raphé neurones after transplantation to the adult rat central nervous system. II. Grafts to the hippocampus. Experimental brain research. vol 70. issue 2. 1988-07-29. PMID:2454837. |
a rich outgrowth of 5ht-immunoreactive varicose processes was evident, with the same pattern as the 5ht innervation by the mesencephalic raphé grafts, and as in the normal hippocampus. |
1988-07-29 |
2023-08-11 |
rat |
N A Otmakho. [Action of mediators on pyramidal and nonpyramidal neurons in slices of the guinea pig hippocampus]. Neirofiziologiia = Neurophysiology. vol 20. issue 1. 1988-07-26. PMID:2898102. |
effects of acetylcholine (ach), norepinephrine (ne), 5-hydroxytryptamine (5-ht) and gamma-aminobutyric acid (gaba) on the background activity were tested in the field ca3 in the guinea pig hippocampal slices. |
1988-07-26 |
2023-08-11 |
Not clear |
S L Carlson, D L Felten, S Livnat, S Y Felte. Alterations of monoamines in specific central autonomic nuclei following immunization in mice. Brain, behavior, and immunity. vol 1. issue 1. 1988-07-22. PMID:3451782. |
serotonin was decreased in the hippocampus on day 2, was decreased in the pvn and supraoptic nucleus on day 4, and was increased in the nucleus tractus solitarius (nts) on day 2. |
1988-07-22 |
2023-08-11 |
mouse |
M E Newman, B Lere. Chronic electroconvulsive shock and desimipramine reduce the degree of inhibition by 5-HT and carbachol of forskolin-stimulated adenylate cyclase in rat hippocampal membranes. European journal of pharmacology. vol 148. issue 2. 1988-07-15. PMID:3378574. |
chronic electroconvulsive shock and desimipramine reduce the degree of inhibition by 5-ht and carbachol of forskolin-stimulated adenylate cyclase in rat hippocampal membranes. |
1988-07-15 |
2023-08-11 |
rat |
M E Newman, B Lere. Chronic electroconvulsive shock and desimipramine reduce the degree of inhibition by 5-HT and carbachol of forskolin-stimulated adenylate cyclase in rat hippocampal membranes. European journal of pharmacology. vol 148. issue 2. 1988-07-15. PMID:3378574. |
the degree of inhibition of forskolin-stimulated adenylate cyclase activity by 5-ht and by carbachol in hippocampal membranes was significantly reduced after administration of either chronic ecs (10 days) or desimipramine (10 mg/kg i.p. |
1988-07-15 |
2023-08-11 |
rat |
M Santiago, A Machado, F Reinoso-Suárez, J Can. Changes in biogenic amines in rat hippocampus during development and aging. Life sciences. vol 42. issue 24. 1988-07-08. PMID:2453775. |
the effects of postnatal development and aging on the concentration of dopamine, noradrenaline, serotonin and their principle metabolites have been studied in the hippocampus of the rat. |
1988-07-08 |
2023-08-11 |
rat |
M Santiago, A Machado, F Reinoso-Suárez, J Can. Changes in biogenic amines in rat hippocampus during development and aging. Life sciences. vol 42. issue 24. 1988-07-08. PMID:2453775. |
these findings led to the conclusion that the neurotransmitters: noradrenaline and serotonin, are developed in the hippocampus during the first three months. |
1988-07-08 |
2023-08-11 |
rat |