| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C J Fowler, G Thorell, E Sundström, T Arche. Norepinephrine-stimulated inositol phospholipid breakdown in the rat cerebral cortex following serotoninergic lesion. Journal of neural transmission. vol 73. issue 3. 1989-02-23. PMID:2850349. |
treatment of rats with 5,7-dihydroxytryptamine and dsp4 produced selective depletions of serotonin (79-95%) and ne (69-85%), respectively, in cortical and hippocampal brain regions. |
1989-02-23 |
2023-08-11 |
rat |
| P Blier, C de Montign. Modification of 5-HT neuron properties by sustained administration of the 5-HT1A agonist gepirone: electrophysiological studies in the rat brain. Synapse (New York, N.Y.). vol 1. issue 5. 1989-02-23. PMID:2905533. |
the responsiveness of postsynaptic dorsal hippocampus pyramidal neurons to 5-ht, 8-oh-dpat, and gepirone was not altered by the 14-day gepirone treatment. |
1989-02-23 |
2023-08-11 |
rat |
| P H Desan, W W Woodmansee, S M Ryan, T K Smock, S F Maie. Monoamine neurotransmitters and metabolites during the estrous cycle, pregnancy, and the postpartum period. Pharmacology, biochemistry, and behavior. vol 30. issue 3. 1989-02-23. PMID:3211964. |
since monoamine systems have been implicated in the control of these behaviors, the present study examined the tissue concentrations of norepinephrine (ne), dopamine (da), and serotonin (5ht) and their primary metabolites dihydroxyphenylglycol (dhpg), 3-methoxy-4-hydroxyphenylglycol (mhpg), 3,4-dihydroxyphenylacetic acid (dopac), and 5-hydroxyindoleacetic acid (5hiaa) in the anterior cerebral cortex, hippocampus, and cerebellum during the estrous cycle, late pregnancy, and the early postpartum period. |
1989-02-23 |
2023-08-11 |
rat |
| D Wirtshafter, M A Klitenick, K E Asi. Is dopamine involved in the hyperactivity produced by injections of muscimol into the median raphe nucleus? Pharmacology, biochemistry, and behavior. vol 30. issue 3. 1989-02-23. PMID:3211966. |
muscimol injections resulted in pronounced hyperactivity which was accompanied by a decrease in serotonin metabolism within the hippocampus and an increase in dopamine metabolism within the nucleus accumbens. |
1989-02-23 |
2023-08-11 |
Not clear |
| A Daszuta, R E Strecker, P Brundin, A Björklun. Serotonin neurons grafted to the adult rat hippocampus. I. Time course of growth as studied by immunohistochemistry and biochemistry. Brain research. vol 458. issue 1. 1989-02-22. PMID:2463040. |
serotonin neurons grafted to the adult rat hippocampus. |
1989-02-22 |
2023-08-11 |
rat |
| A Daszuta, R E Strecker, P Brundin, A Björklun. Serotonin neurons grafted to the adult rat hippocampus. I. Time course of growth as studied by immunohistochemistry and biochemistry. Brain research. vol 458. issue 1. 1989-02-22. PMID:2463040. |
a regression analysis revealed a significant inverse correlation between the hippocampal 5-ht concentration and the 5-hiaa:5-ht ratio in the graft-reinnervated hippocampal formation. |
1989-02-22 |
2023-08-11 |
rat |
| G Lombardi, M Beni, V Carla', G Toffano, F Moron. Differential actions of neurotrophic factors on lesion-induced damage of the serotonergic neurons projecting to the hippocampus. Brain research. vol 458. issue 2. 1989-02-22. PMID:2463051. |
this lesion selectively reduced the content of 5-ht and 5-hiaa in the ipsilateral hippocampus. |
1989-02-22 |
2023-08-11 |
rat |
| G Lombardi, M Beni, V Carla', G Toffano, F Moron. Differential actions of neurotrophic factors on lesion-induced damage of the serotonergic neurons projecting to the hippocampus. Brain research. vol 458. issue 2. 1989-02-22. PMID:2463051. |
daily intraperitoneal injection of gm1-ganglioside (30 mg/kg/day for 6-14 days) significantly reduced the injury-induced loss of hippocampal 5-ht and 5-hiaa content. |
1989-02-22 |
2023-08-11 |
rat |
| G Lombardi, M Beni, V Carla', G Toffano, F Moron. Differential actions of neurotrophic factors on lesion-induced damage of the serotonergic neurons projecting to the hippocampus. Brain research. vol 458. issue 2. 1989-02-22. PMID:2463051. |
twice a week for 2 weeks) which was able to increase, in the same animals, the cortical choline acetyltransferase activity, failed to affect the lesion-induced reduction of 5-ht and of 5-hiaa in the hippocampus. |
1989-02-22 |
2023-08-11 |
rat |
| S Bourgoin, M Pohl, M Hirsch, A Mauborgne, F Cesselin, M Hamo. Direct stimulatory effect of calcitonin on [3H]5-hydroxytryptamine release from the rat spinal cord. European journal of pharmacology. vol 156. issue 1. 1989-02-21. PMID:2463177. |
the stimulatory effect of porcine and salmon calcitonin on k+-evoked [3h]5-ht overflow was found with slices from the dorsal or the ventral half of the lumbar enlargement but not with hippocampal or hypothalamic slices. |
1989-02-21 |
2023-08-11 |
human |
| P Blier, C de Montigny, D Tardi. Short-term lithium treatment enhances responsiveness of postsynaptic 5-HT1A receptors without altering 5-HT autoreceptor sensitivity: an electrophysiological study in the rat brain. Synapse (New York, N.Y.). vol 1. issue 3. 1989-02-21. PMID:2850622. |
in the first part of the present study, the effect of lithium on the function of terminal 5-ht autoreceptors was assessed by comparing in controls and lithium-treated rats the differential effect of two frequencies of stimulation (0.8 and 5 hz) and that of methiothepin, a terminal 5-ht autoreceptor antagonist, on the effectiveness of the electrical activation of the ascending 5-ht pathway in suppressing dorsal hippocampus pyramidal neuron firing activity. |
1989-02-21 |
2023-08-11 |
rat |
| S N Mitchell, P J Thoma. Effect of restraint stress and anxiolytics on 5-HT turnover in rat brain. Pharmacology. vol 37. issue 2. 1989-02-21. PMID:2905483. |
in male tuck aha rats, restraint stress had no effect on 5-hydroxytryptamine (5-ht) levels in the frontal cortex, amygdala, hypothalamus and hippocampus, but produced a significant increase in 5-hydroxyindoleacetic acid (5-hiaa) levels in the amygdala after 120 and 180 min, and in the hypothalamus after 180 min. |
1989-02-21 |
2023-08-11 |
rat |
| G Lombardi, M Beni, A Consolazione, F Moron. Lesioning and recovery of the serotoninergic hippocampal afferents: differential effects of GM1 ganglioside. Neuropharmacology. vol 27. issue 11. 1989-02-09. PMID:2462696. |
the effects of administration of gm1 ganglioside on the content of 5-ht and of 5-hiaa in the hippocampus after two different types of lesions of the serotoninergic afferents to the hippocampus were studied. |
1989-02-09 |
2023-08-11 |
Not clear |
| G Lombardi, M Beni, A Consolazione, F Moron. Lesioning and recovery of the serotoninergic hippocampal afferents: differential effects of GM1 ganglioside. Neuropharmacology. vol 27. issue 11. 1989-02-09. PMID:2462696. |
this caused a monolateral decrease of the content of 5-ht and of 5-hiaa in the hippocampal by 60 and 38%, respectively. |
1989-02-09 |
2023-08-11 |
Not clear |
| G Lombardi, M Beni, A Consolazione, F Moron. Lesioning and recovery of the serotoninergic hippocampal afferents: differential effects of GM1 ganglioside. Neuropharmacology. vol 27. issue 11. 1989-02-09. PMID:2462696. |
the second lesion consisted of electrolytic damage to a mesencephalic area, where scattered 5-ht cells projecting to the hippocampus are known to be located. |
1989-02-09 |
2023-08-11 |
Not clear |
| G Lombardi, M Beni, A Consolazione, F Moron. Lesioning and recovery of the serotoninergic hippocampal afferents: differential effects of GM1 ganglioside. Neuropharmacology. vol 27. issue 11. 1989-02-09. PMID:2462696. |
the content of 5-ht and 5-hiaa in the hippocampus, ipsilateral to this lesion, decreased by 37 and by 26%, respectively. |
1989-02-09 |
2023-08-11 |
Not clear |
| M Johnson, G R Hanson, J W Gib. Effects of dopaminergic and serotonergic receptor blockade on neurochemical changes induced by acute administration of methamphetamine and 3,4-methylenedioxymethamphetamine. Neuropharmacology. vol 27. issue 11. 1989-02-09. PMID:3144655. |
pretreatment with the da receptor antagonist, haloperidol, failed to prevent the decreases in the activity of tryptophan hydroxylase and the concentration of serotonin (5-ht) in the frontal cortex, hippocampus and neostriatum 1 hr after a single administration of methamphetamine. |
1989-02-09 |
2023-08-11 |
Not clear |
| M Johnson, G R Hanson, J W Gib. Effects of dopaminergic and serotonergic receptor blockade on neurochemical changes induced by acute administration of methamphetamine and 3,4-methylenedioxymethamphetamine. Neuropharmacology. vol 27. issue 11. 1989-02-09. PMID:3144655. |
pretreatment with methiothepin an antagonist of both da and 5-ht receptors, failed to prevent the decline in activity of tryptophan hydroxylase but did attenuate the decreases in concentrations of 5-ht measured in the frontal cortex and hippocampus. |
1989-02-09 |
2023-08-11 |
Not clear |
| A C Scallet, G W Lipe, S F Ali, R R Holson, C H Frith, W Slikke. Neuropathological evaluation by combined immunohistochemistry and degeneration-specific methods: application to methylenedioxymethamphetamine. Neurotoxicology. vol 9. issue 3. 1989-01-19. PMID:2904668. |
four months after two 40 mg/kg oral doses per day for four days, rats had a reduced neurochemical content of 5-ht in the hippocampus, and fewer immunostainable 5-ht axons per unit area in the hippocampal stratum lacunosum but no change in brain-stem neurochemical 5-ht content or in the numeric density of 5-ht-positive cell bodies in the dorsal raphe nucleus. |
1989-01-19 |
2023-08-11 |
rat |
| M S Kleven, W L Woolverton, L S Seide. Lack of long-term monoamine depletions following repeated or continuous exposure to cocaine. Brain research bulletin. vol 21. issue 2. 1988-12-27. PMID:2461246. |
none of the regimens produced long-lasting depletions of dopamine (da), serotonin (5-ht), or major metabolites in striatum, hippocampus, hypothalamus, or somatosensory cortex. |
1988-12-27 |
2023-08-11 |
rat |