| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M S Kleven, C R Schuster, L S Seide. Effect of depletion of brain serotonin by repeated fenfluramine on neurochemical and anorectic effects of acute fenfluramine. The Journal of pharmacology and experimental therapeutics. vol 246. issue 3. 1988-10-21. PMID:2458447. |
acute administration of fenfluramine produced a dose-dependent decrease in milk intake and 5-ht and 5-hydroxyindoleacetic acid (5-hiaa) levels in cortex, hypothalamus and hippocampus. |
1988-10-21 |
2023-08-11 |
rat |
| M S Kleven, C R Schuster, L S Seide. Effect of depletion of brain serotonin by repeated fenfluramine on neurochemical and anorectic effects of acute fenfluramine. The Journal of pharmacology and experimental therapeutics. vol 246. issue 3. 1988-10-21. PMID:2458447. |
levels of 5-ht and 5-hiaa in somatosensory cortex, hypothalamus, striatum and hippocampus were depleted significantly 2 weeks after the last daily fenfluramine injection. |
1988-10-21 |
2023-08-11 |
rat |
| N Roper. Inhibitory action of serotonin in CA1 hippocampal neurons in vitro. Neuroscience. vol 26. issue 1. 1988-10-20. PMID:2843792. |
inhibitory action of serotonin in ca1 hippocampal neurons in vitro. |
1988-10-20 |
2023-08-11 |
rat |
| N Roper. Inhibitory action of serotonin in CA1 hippocampal neurons in vitro. Neuroscience. vol 26. issue 1. 1988-10-20. PMID:2843792. |
the ionic mechanism of the inhibitory effect of serotonin was investigated in vitro in the ca1 region of the rat hippocampus by extra- and intracellular recordings. |
1988-10-20 |
2023-08-11 |
rat |
| G Szabó, G L Kovács, G Telegd. Brain monoamines are involved in mediating the action of neurohypophyseal peptide hormones on ethanol tolerance. Acta physiologica Hungarica. vol 71. issue 3. 1988-10-18. PMID:3421121. |
in the peptide-pretreated animals the na level was increased in the hypothalamus, the da level in the striatum, and the 5-ht level in the hippocampus and striatum. |
1988-10-18 |
2023-08-11 |
mouse |
| G S Alemà, S Maccari, M A Micci, F R Patacchiol. Hippocampal serotonin in the regulation of the hypothalamo-pituitary-adrenocortical axis (HPAA) stress response. Pharmacological research communications. vol 20. issue 5. 1988-10-17. PMID:2458602. |
hippocampal serotonin in the regulation of the hypothalamo-pituitary-adrenocortical axis (hpaa) stress response. |
1988-10-17 |
2023-08-11 |
Not clear |
| M Muramatsu, J Tamaki-Ohashi, C Usuki, H Araki, H Aihar. Serotonin-2 receptor-mediated regulation of release of acetylcholine by minaprine in cholinergic nerve terminal of hippocampus of rat. Neuropharmacology. vol 27. issue 6. 1988-10-17. PMID:3419543. |
5-hydroxytryptamine (5-ht) inhibited the k+-induced release of [3h]acetylcholine [( 3h]ach) from slices of the hippocampus of the rat, dose-dependently. |
1988-10-17 |
2023-08-11 |
rat |
| M Muramatsu, J Tamaki-Ohashi, C Usuki, H Araki, H Aihar. Serotonin-2 receptor-mediated regulation of release of acetylcholine by minaprine in cholinergic nerve terminal of hippocampus of rat. Neuropharmacology. vol 27. issue 6. 1988-10-17. PMID:3419543. |
minaprine inhibited the bindings of [3h]5-ht, [3h]8-oh-dpat and [3h]ketanserin in the hippocampus. |
1988-10-17 |
2023-08-11 |
rat |
| M Muramatsu, J Tamaki-Ohashi, C Usuki, H Araki, H Aihar. Serotonin-2 receptor-mediated regulation of release of acetylcholine by minaprine in cholinergic nerve terminal of hippocampus of rat. Neuropharmacology. vol 27. issue 6. 1988-10-17. PMID:3419543. |
by electrolytic lesioning of the medial septum, the k+-induced release of [3h]ach from the slices of hippocampus was significantly reduced and the release was no longer inhibited by 5-ht. |
1988-10-17 |
2023-08-11 |
rat |
| M Muramatsu, J Tamaki-Ohashi, C Usuki, H Araki, H Aihar. Serotonin-2 receptor-mediated regulation of release of acetylcholine by minaprine in cholinergic nerve terminal of hippocampus of rat. Neuropharmacology. vol 27. issue 6. 1988-10-17. PMID:3419543. |
the lesioning significantly decreased the binding of [3h]ketanserin in the hippocampus, with hardly any reduction in the binding of [3h]5-ht and [3h]8-oh-dpat. |
1988-10-17 |
2023-08-11 |
rat |
| M Martire, P Navarra, G Pistritto, P Prezios. Adrenal steroid-induced changes in serotonin receptors in rat hippocampus and hypothalamus. Pharmacological research communications. vol 20. issue 5. 1988-10-17. PMID:3420146. |
adrenal steroid-induced changes in serotonin receptors in rat hippocampus and hypothalamus. |
1988-10-17 |
2023-08-11 |
rat |
| E O'Hearn, G Battaglia, E B De Souza, M J Kuhar, M E Mollive. Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 8. issue 8. 1988-10-07. PMID:2457659. |
regional differences in drug toxicity are exemplified by partial sparing of 5-ht axons in hippocampus, lateral hypothalamus, basal forebrain, and in some areas of neocortex. |
1988-10-07 |
2023-08-11 |
rat |
| L E Mello, Z A Bortolotto, E A Cavalheir. Brain indoleamines in alloxan- and streptozotocin-induced diabetic rats. Journal of neurochemistry. vol 51. issue 3. 1988-09-26. PMID:2970524. |
levels of brain indoleamines exhibited a strong positive correlation with wet-dog shakes (an index of 5-ht activity) elicited by hippocampal stimulation. |
1988-09-26 |
2023-08-11 |
rat |
| J Sawynok, A Rei. Role of ascending and descending serotonergic pathways in the antinociceptive effect of baclofen. Naunyn-Schmiedeberg's archives of pharmacology. vol 337. issue 4. 1988-09-16. PMID:3405312. |
lesions to the nucleus raphe medianus produced a marked depletion of 5-ht in the hippocampus and produced the same effect on baclofen. |
1988-09-16 |
2023-08-11 |
rat |
| F C Zhou, S B Auerbach, E C Azmiti. Transplanted raphe and hippocampal fetal neurons do not displace afferent inputs to the dorsal hippocampus from serotonergic neurons in the median raphe nucleus of the rat. Brain research. vol 450. issue 1-2. 1988-09-15. PMID:3401722. |
to determine if fetal transplants can substitute for or suppress intrinsic serotonergic (5-ht) innervation, we studied the relationship between transplanted and the endogenous raphe neurons projecting to the hippocampus. |
1988-09-15 |
2023-08-11 |
rat |
| F C Zhou, S B Auerbach, E C Azmiti. Transplanted raphe and hippocampal fetal neurons do not displace afferent inputs to the dorsal hippocampus from serotonergic neurons in the median raphe nucleus of the rat. Brain research. vol 450. issue 1-2. 1988-09-15. PMID:3401722. |
fetal raphe transplants produced a 5-ht hyperinnervation of dorsal hippocampus in adult rats. |
1988-09-15 |
2023-08-11 |
rat |
| F C Zhou, S B Auerbach, E C Azmiti. Transplanted raphe and hippocampal fetal neurons do not displace afferent inputs to the dorsal hippocampus from serotonergic neurons in the median raphe nucleus of the rat. Brain research. vol 450. issue 1-2. 1988-09-15. PMID:3401722. |
changes in the innervation pattern and 5-ht level in the dorsal hippocampus occur following transplantation of fetal tissue. |
1988-09-15 |
2023-08-11 |
rat |
| W Slikker, S F Ali, A C Scallet, C H Frith, G D Newport, J R Baile. Neurochemical and neurohistological alterations in the rat and monkey produced by orally administered methylenedioxymethamphetamine (MDMA). Toxicology and applied pharmacology. vol 94. issue 3. 1988-09-02. PMID:2456631. |
brain regions including the hippocampus (h), caudate nucleus (cn), hypothalamus (hy), frontal cortex (fc), and brain stem (bs) were analyzed by hplc with electrochemical detection for concentrations of dopamine (da), dihydroxyphenylacetic acid (dopac), homovanillic acid (hva), serotonin (5-ht), 5-hydroxyindoleacetic acid (5-hiaa), and norepinephrine (ne). |
1988-09-02 |
2023-08-11 |
rat |
| P Blier, Y Chaput, C de Montign. Long-term 5-HT reuptake blockade, but not monoamine oxidase inhibition, decreases the function of terminal 5-HT autoreceptors: an electrophysiological study in the rat brain. Naunyn-Schmiedeberg's archives of pharmacology. vol 337. issue 3. 1988-08-22. PMID:3260661. |
unitary extracellular recordings were obtained from ca3 dorsal hippocampus pyramidal neurons under chloral hydrate anesthesia in rats treated daily with fluoxetine (10 mg/kg/day x 14 days), a selective 5-ht reuptake blocker, or clorgyline (1 mg/kg/day x 21 days), an inhibitor of type a monoamine oxidase. |
1988-08-22 |
2023-08-11 |
rat |
| P Blier, Y Chaput, C de Montign. Long-term 5-HT reuptake blockade, but not monoamine oxidase inhibition, decreases the function of terminal 5-HT autoreceptors: an electrophysiological study in the rat brain. Naunyn-Schmiedeberg's archives of pharmacology. vol 337. issue 3. 1988-08-22. PMID:3260661. |
the function of the terminal 5-ht autoreceptors was assessed by comparing the effectiveness of the electrical stimulation of the ascending 5-ht pathway on the firing activity of hippocampus pyramidal neurons prior to, and following, the administration of methiothepin, an antagonist of the terminal 5-ht autoreceptor, and, by determining the ratio of effectiveness of 0.8 hz (s1) and 5 hz (s2) stimulations. |
1988-08-22 |
2023-08-11 |
rat |