| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Lombardi, M Beni, V Carla', G Toffano, F Moron. Differential actions of neurotrophic factors on lesion-induced damage of the serotonergic neurons projecting to the hippocampus. Brain research. vol 458. issue 2. 1989-02-22. PMID:2463051. |
twice a week for 2 weeks) which was able to increase, in the same animals, the cortical choline acetyltransferase activity, failed to affect the lesion-induced reduction of 5-ht and of 5-hiaa in the hippocampus. |
1989-02-22 |
2023-08-11 |
rat |
| S Bourgoin, M Pohl, M Hirsch, A Mauborgne, F Cesselin, M Hamo. Direct stimulatory effect of calcitonin on [3H]5-hydroxytryptamine release from the rat spinal cord. European journal of pharmacology. vol 156. issue 1. 1989-02-21. PMID:2463177. |
the stimulatory effect of porcine and salmon calcitonin on k+-evoked [3h]5-ht overflow was found with slices from the dorsal or the ventral half of the lumbar enlargement but not with hippocampal or hypothalamic slices. |
1989-02-21 |
2023-08-11 |
human |
| P Blier, C de Montigny, D Tardi. Short-term lithium treatment enhances responsiveness of postsynaptic 5-HT1A receptors without altering 5-HT autoreceptor sensitivity: an electrophysiological study in the rat brain. Synapse (New York, N.Y.). vol 1. issue 3. 1989-02-21. PMID:2850622. |
in the first part of the present study, the effect of lithium on the function of terminal 5-ht autoreceptors was assessed by comparing in controls and lithium-treated rats the differential effect of two frequencies of stimulation (0.8 and 5 hz) and that of methiothepin, a terminal 5-ht autoreceptor antagonist, on the effectiveness of the electrical activation of the ascending 5-ht pathway in suppressing dorsal hippocampus pyramidal neuron firing activity. |
1989-02-21 |
2023-08-11 |
rat |
| S N Mitchell, P J Thoma. Effect of restraint stress and anxiolytics on 5-HT turnover in rat brain. Pharmacology. vol 37. issue 2. 1989-02-21. PMID:2905483. |
in male tuck aha rats, restraint stress had no effect on 5-hydroxytryptamine (5-ht) levels in the frontal cortex, amygdala, hypothalamus and hippocampus, but produced a significant increase in 5-hydroxyindoleacetic acid (5-hiaa) levels in the amygdala after 120 and 180 min, and in the hypothalamus after 180 min. |
1989-02-21 |
2023-08-11 |
rat |
| G Lombardi, M Beni, A Consolazione, F Moron. Lesioning and recovery of the serotoninergic hippocampal afferents: differential effects of GM1 ganglioside. Neuropharmacology. vol 27. issue 11. 1989-02-09. PMID:2462696. |
the effects of administration of gm1 ganglioside on the content of 5-ht and of 5-hiaa in the hippocampus after two different types of lesions of the serotoninergic afferents to the hippocampus were studied. |
1989-02-09 |
2023-08-11 |
Not clear |
| G Lombardi, M Beni, A Consolazione, F Moron. Lesioning and recovery of the serotoninergic hippocampal afferents: differential effects of GM1 ganglioside. Neuropharmacology. vol 27. issue 11. 1989-02-09. PMID:2462696. |
this caused a monolateral decrease of the content of 5-ht and of 5-hiaa in the hippocampal by 60 and 38%, respectively. |
1989-02-09 |
2023-08-11 |
Not clear |
| G Lombardi, M Beni, A Consolazione, F Moron. Lesioning and recovery of the serotoninergic hippocampal afferents: differential effects of GM1 ganglioside. Neuropharmacology. vol 27. issue 11. 1989-02-09. PMID:2462696. |
the second lesion consisted of electrolytic damage to a mesencephalic area, where scattered 5-ht cells projecting to the hippocampus are known to be located. |
1989-02-09 |
2023-08-11 |
Not clear |
| G Lombardi, M Beni, A Consolazione, F Moron. Lesioning and recovery of the serotoninergic hippocampal afferents: differential effects of GM1 ganglioside. Neuropharmacology. vol 27. issue 11. 1989-02-09. PMID:2462696. |
the content of 5-ht and 5-hiaa in the hippocampus, ipsilateral to this lesion, decreased by 37 and by 26%, respectively. |
1989-02-09 |
2023-08-11 |
Not clear |
| M Johnson, G R Hanson, J W Gib. Effects of dopaminergic and serotonergic receptor blockade on neurochemical changes induced by acute administration of methamphetamine and 3,4-methylenedioxymethamphetamine. Neuropharmacology. vol 27. issue 11. 1989-02-09. PMID:3144655. |
pretreatment with the da receptor antagonist, haloperidol, failed to prevent the decreases in the activity of tryptophan hydroxylase and the concentration of serotonin (5-ht) in the frontal cortex, hippocampus and neostriatum 1 hr after a single administration of methamphetamine. |
1989-02-09 |
2023-08-11 |
Not clear |
| M Johnson, G R Hanson, J W Gib. Effects of dopaminergic and serotonergic receptor blockade on neurochemical changes induced by acute administration of methamphetamine and 3,4-methylenedioxymethamphetamine. Neuropharmacology. vol 27. issue 11. 1989-02-09. PMID:3144655. |
pretreatment with methiothepin an antagonist of both da and 5-ht receptors, failed to prevent the decline in activity of tryptophan hydroxylase but did attenuate the decreases in concentrations of 5-ht measured in the frontal cortex and hippocampus. |
1989-02-09 |
2023-08-11 |
Not clear |
| A C Scallet, G W Lipe, S F Ali, R R Holson, C H Frith, W Slikke. Neuropathological evaluation by combined immunohistochemistry and degeneration-specific methods: application to methylenedioxymethamphetamine. Neurotoxicology. vol 9. issue 3. 1989-01-19. PMID:2904668. |
four months after two 40 mg/kg oral doses per day for four days, rats had a reduced neurochemical content of 5-ht in the hippocampus, and fewer immunostainable 5-ht axons per unit area in the hippocampal stratum lacunosum but no change in brain-stem neurochemical 5-ht content or in the numeric density of 5-ht-positive cell bodies in the dorsal raphe nucleus. |
1989-01-19 |
2023-08-11 |
rat |
| M S Kleven, W L Woolverton, L S Seide. Lack of long-term monoamine depletions following repeated or continuous exposure to cocaine. Brain research bulletin. vol 21. issue 2. 1988-12-27. PMID:2461246. |
none of the regimens produced long-lasting depletions of dopamine (da), serotonin (5-ht), or major metabolites in striatum, hippocampus, hypothalamus, or somatosensory cortex. |
1988-12-27 |
2023-08-11 |
rat |
| E Mocaër, M C Rettori, A Kamou. Pharmacological antidepressive effects and tianeptine-induced 5-HT uptake increase. Clinical neuropharmacology. vol 11 Suppl 2. 1988-12-20. PMID:3180116. |
tianeptine, in contrast to tricyclic antidepressants which inhibit 5-ht uptake, stimulates serotonin uptake ex vivo in the rat brain (cortex, hippocampus) and rat as well as human platelets following both acute and chronic administration. |
1988-12-20 |
2023-08-11 |
mouse |
| E Mocaër, M C Rettori, A Kamou. Pharmacological antidepressive effects and tianeptine-induced 5-HT uptake increase. Clinical neuropharmacology. vol 11 Suppl 2. 1988-12-20. PMID:3180116. |
tianeptine increases the firing rate of hippocampus pyramidal cells which could be consistent with tianeptine-induced serotonin uptake stimulation. |
1988-12-20 |
2023-08-11 |
mouse |
| T Kubo, S Shibanoki, A Matsumoto, K Tsuda, K Ishikaw. Portacaval anastomosis attenuates the impairing effect of cyproheptadine on avoidance learning in rats--an involvement of the serotonergic system. Behavioural brain research. vol 30. issue 3. 1988-12-06. PMID:3178999. |
significant increases in the concentration of 5-hydroxyindoleacetic acid, a metabolite of 5-hydroxytryptamine (5-ht), in all regions examined and the turnover rate of this indoleamine transmitter in the hippocampus, hypothalamus, midbrain and medulla oblongata were observed in pca rats in comparison with sham-operated controls. |
1988-12-06 |
2023-08-11 |
rat |
| M A Harrington, D Oksenberg, S J Peroutk. 5-Hydroxytryptamine1A receptors are linked to a Gi-adenylate cyclase complex in rat hippocampus. European journal of pharmacology. vol 154. issue 1. 1988-12-01. PMID:2972552. |
the ability of 5-hydroxytryptamine (5-ht) and the 5-ht1a selective agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat) to modulate adenylate cyclase activity was measured in rat hippocampus. |
1988-12-01 |
2023-08-11 |
rat |
| P Nencini, W L Woolverton, L S Seide. Enhancement of morphine-induced analgesia after repeated injections of methylenedioxymethamphetamine. Brain research. vol 457. issue 1. 1988-11-23. PMID:2901895. |
mdma selectively depleted 5-ht in the cortex, hippocampus, striatum, brainstem and in the cervical portion of spinal cord. |
1988-11-23 |
2023-08-11 |
rat |
| R Bouhelal, L Smounya, J Bockaer. 5-HT1B receptors are negatively coupled with adenylate cyclase in rat substantia nigra. European journal of pharmacology. vol 151. issue 2. 1988-11-23. PMID:2971554. |
cgs 120 66b was almost as potent (ec50 = 100 nm) as 5-ht to inhibit the forskolin-stimulated adenylate cyclase in rat substantia nigra homogenates whereas this preferential 5-ht1b agonist was 100 times less potent than 5-ht in hippocampus guinea pig homogenates. |
1988-11-23 |
2023-08-11 |
rat |
| A Adell, R Trullas, E Gelp. Time course of changes in serotonin and noradrenaline in rat brain after predictable or unpredictable shock. Brain research. vol 459. issue 1. 1988-11-21. PMID:2458804. |
5-ht metabolism expressed as the 5-hiaa/5-ht ratio, was significantly increased 30 min after predictable shock in all regions except the locus coeruleus and hippocampus. |
1988-11-21 |
2023-08-11 |
rat |
| b' C Su\\xc3\\xb1ol, J M Tusell, E Gelp\\xc3\\xad, E Rodr\\xc3\\xadguez-Farr\\xc3\\xa. Regional concentrations of GABA, serotonin and noradrenaline in brain at onset of seizures induced by lindane (gamma-hexachlorocyclohexane). Neuropharmacology. vol 27. issue 7. 1988-10-24. PMID:2458533.' |
the inhibitory neurotransmitter gamma-aminobutyric acid (gaba) and the biogenic amines noradrenaline (na) and serotonin (5-ht), as well as its corresponding acidic metabolite, were determined by high performance liquid chromatography with fluorimetric or electrochemical detection in different areas of the brain: hippocampus, mesencephalon, colliculi, frontal cortex, parietal cortex, striatum and thalamus. |
1988-10-24 |
2023-08-11 |
Not clear |