| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J M Zgombick, S G Beck, C D Mahle, B Craddock-Royal, S Maayan. Pertussis toxin-sensitive guanine nucleotide-binding protein(S) couple adenosine A1 and 5-hydroxytryptamine1A receptors to the same effector systems in rat hippocampus: biochemical and electrophysiological studies. Molecular pharmacology. vol 35. issue 4. 1989-05-23. PMID:2495434. |
in the present study, rat hippocampal adenosine (ad) and 5-hydroxytryptamine (5-ht) receptors were chosen to test this possibility using biochemical and electrophysiological techniques. |
1989-05-23 |
2023-08-11 |
rat |
| G Richter-Levin, M Sega. Serotonin releasers modulate reactivity of the rat hippocampus to afferent stimulation. Neuroscience letters. vol 94. issue 1-2. 1989-05-16. PMID:3241665. |
serotonin releasers modulate reactivity of the rat hippocampus to afferent stimulation. |
1989-05-16 |
2023-08-11 |
rat |
| B Daschmann, C Allgaier, R Nakov, G Herttin. Staurosporine counteracts the phorbol ester-induced enhancement of neurotransmitter release in hippocampus. Archives internationales de pharmacodynamie et de therapie. vol 296. 1989-05-10. PMID:2907278. |
slices of rabbit hippocampus, prelabelled with either [3h]noradrenaline, [3h]5-hydroxytryptamine or [3h]choline were superfused with physiological medium. |
1989-05-10 |
2023-08-11 |
rabbit |
| T Sharp, S R Bramwell, D G Grahame-Smit. 5-HT1 agonists reduce 5-hydroxytryptamine release in rat hippocampus in vivo as determined by brain microdialysis. British journal of pharmacology. vol 96. issue 2. 1989-05-05. PMID:2466516. |
5-ht1 agonists reduce 5-hydroxytryptamine release in rat hippocampus in vivo as determined by brain microdialysis. |
1989-05-05 |
2023-08-11 |
rat |
| T Sharp, S R Bramwell, D G Grahame-Smit. 5-HT1 agonists reduce 5-hydroxytryptamine release in rat hippocampus in vivo as determined by brain microdialysis. British journal of pharmacology. vol 96. issue 2. 1989-05-05. PMID:2466516. |
an intracerebral perfusion method, brain microdialysis, was used to assess changes of 5-hydroxytryptamine (5-ht) release in the ventral hippocampus of the chloral hydrate-anaesthetized rat in response to systemic administration of a variety of 5-ht1 receptor agonists. |
1989-05-05 |
2023-08-11 |
rat |
| T Sharp, S R Bramwell, D G Grahame-Smit. 5-HT1 agonists reduce 5-hydroxytryptamine release in rat hippocampus in vivo as determined by brain microdialysis. British journal of pharmacology. vol 96. issue 2. 1989-05-05. PMID:2466516. |
a stable output of reliably detectable endogenous 5-ht was measured in dialysates collected from ventral hippocampus with the 5-ht reuptake inhibitor, citalopram, present in the perfusion medium. |
1989-05-05 |
2023-08-11 |
rat |
| T Sharp, S R Bramwell, D G Grahame-Smit. 5-HT1 agonists reduce 5-hydroxytryptamine release in rat hippocampus in vivo as determined by brain microdialysis. British journal of pharmacology. vol 96. issue 2. 1989-05-05. PMID:2466516. |
under these conditions the putative 5-ht1a agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat) caused a dose-dependent (5-250 micrograms kg-1, s.c.) reduction of 5-ht in hippocampal dialysates. |
1989-05-05 |
2023-08-11 |
rat |
| T Sharp, S R Bramwell, D G Grahame-Smit. 5-HT1 agonists reduce 5-hydroxytryptamine release in rat hippocampus in vivo as determined by brain microdialysis. British journal of pharmacology. vol 96. issue 2. 1989-05-05. PMID:2466516. |
similarly, the putative 5-ht1a agonists gepirone (5 mg kg-1, s.c.), ipsapirone (5 mg kg-1, s.c.) and buspirone (5 mg kg-1, s.c.) markedly reduced levels of 5-ht in hippocampal perfusates whereas their common metabolite 1-(2-pyrimidinyl) piperazine (5 mg kg-1, s.c.), which does not bind to central 5-ht1a recognition sites, had no effect. |
1989-05-05 |
2023-08-11 |
rat |
| T Sharp, S R Bramwell, D G Grahame-Smit. 5-HT1 agonists reduce 5-hydroxytryptamine release in rat hippocampus in vivo as determined by brain microdialysis. British journal of pharmacology. vol 96. issue 2. 1989-05-05. PMID:2466516. |
5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1h-indole (ru 24969), a drug with reported high affinity for brain 5-ht1b binding sites, also produced a dose-dependent (0.25-5 mg kg-1, s.c.) decrease of hippocampal 5-ht output. |
1989-05-05 |
2023-08-11 |
rat |
| T Sharp, S R Bramwell, D G Grahame-Smit. 5-HT1 agonists reduce 5-hydroxytryptamine release in rat hippocampus in vivo as determined by brain microdialysis. British journal of pharmacology. vol 96. issue 2. 1989-05-05. PMID:2466516. |
these data are direct biochemical evidence that systemically administered putative 5-ht1a and 5-ht1b agonists markedly inhibit 5-ht release in rat ventral hippocampus in vivo. |
1989-05-05 |
2023-08-11 |
rat |
| I Hotta, S Yamawak. Possible involvement of presynaptic 5-HT autoreceptors in effect of lithium on 5-HT release in hippocampus of rat. Neuropharmacology. vol 27. issue 10. 1989-05-02. PMID:3237318. |
possible involvement of presynaptic 5-ht autoreceptors in effect of lithium on 5-ht release in hippocampus of rat. |
1989-05-02 |
2023-08-11 |
rat |
| I Hotta, S Yamawak. Possible involvement of presynaptic 5-HT autoreceptors in effect of lithium on 5-HT release in hippocampus of rat. Neuropharmacology. vol 27. issue 10. 1989-05-02. PMID:3237318. |
the effects of subacute treatment with lithium on the stimulation-induced release of serotonin (5-ht) and the function of 5-ht autoreceptors in the hippocampus and frontal cortex of the rat were studied. |
1989-05-02 |
2023-08-11 |
rat |
| I Hotta, S Yamawak. Possible involvement of presynaptic 5-HT autoreceptors in effect of lithium on 5-HT release in hippocampus of rat. Neuropharmacology. vol 27. issue 10. 1989-05-02. PMID:3237318. |
in the rats treated with lithium for 3 days, the high k+-evoked release of endogenous 5-ht from the slices of hippocampus, but not the slices of frontal cortex, was significantly increased. |
1989-05-02 |
2023-08-11 |
rat |
| I Hotta, S Yamawak. Possible involvement of presynaptic 5-HT autoreceptors in effect of lithium on 5-HT release in hippocampus of rat. Neuropharmacology. vol 27. issue 10. 1989-05-02. PMID:3237318. |
high k+-induced release of [3h]5-ht from the slices of hippocampus of control rats preloaded with [3h]5-ht was decreased when the slices were exposed to 5-ht, while it was increased when they were exposed to methiothepin. |
1989-05-02 |
2023-08-11 |
rat |
| I Hotta, S Yamawak. Possible involvement of presynaptic 5-HT autoreceptors in effect of lithium on 5-HT release in hippocampus of rat. Neuropharmacology. vol 27. issue 10. 1989-05-02. PMID:3237318. |
in the slices of hippocampus from the lithium-treated rats, this inhibitory effect of 5-ht on the release of [3h]5-ht, evoked by either high k+ or electrical stimulation was significantly attenuated. |
1989-05-02 |
2023-08-11 |
rat |
| G Clementi, A Favit, R Curreri, F Nicoletti, U Scapagnin. Repeated calcitonin treatment reduces the stimulation of inositol phospholipid by norepinephrine and serotonin in rat hippocampus and cerebral cortex. Brain research. vol 478. issue 1. 1989-04-27. PMID:2924109. |
repeated calcitonin treatment reduces the stimulation of inositol phospholipid by norepinephrine and serotonin in rat hippocampus and cerebral cortex. |
1989-04-27 |
2023-08-11 |
rat |
| G Clementi, A Favit, R Curreri, F Nicoletti, U Scapagnin. Repeated calcitonin treatment reduces the stimulation of inositol phospholipid by norepinephrine and serotonin in rat hippocampus and cerebral cortex. Brain research. vol 478. issue 1. 1989-04-27. PMID:2924109. |
stimulation of inositol phospholipid hydrolysis by norepinephrine or 5-hydroxytryptamine was reduced in hippocampal or cortical slices from rats repeatedly injected with (asu1.7)eel-calcitonin (2.5 iu/kg i.p.). |
1989-04-27 |
2023-08-11 |
rat |
| G Richter-Levin, M Sega. Raphe cells grafted into the hippocampus can ameliorate spatial memory deficits in rats with combined serotonergic/cholinergic deficiencies. Brain research. vol 478. issue 1. 1989-04-27. PMID:2924115. |
the presence of an active serotonergic graft was examined in the intact rat hippocampus using the serotonin releasing drug fenfluramine (ffa). |
1989-04-27 |
2023-08-11 |
rat |
| F Passarelli, T Costa, O F Almeid. Pertussis toxin inactivates the presynaptic serotonin autoreceptor in the hippocampus. European journal of pharmacology. vol 155. issue 3. 1989-04-27. PMID:3234488. |
pertussis toxin inactivates the presynaptic serotonin autoreceptor in the hippocampus. |
1989-04-27 |
2023-08-11 |
rat |
| F Passarelli, T Costa, O F Almeid. Pertussis toxin inactivates the presynaptic serotonin autoreceptor in the hippocampus. European journal of pharmacology. vol 155. issue 3. 1989-04-27. PMID:3234488. |
the serotonin (5-ht) agonists, d-lysergic acid diethylamide (lsd) and 5-methoxytryptamine (5-me-o-t), dose dependently inhibited the k+-evoked outflow of [3h]5-ht from preloaded rat hippocampal slices in vitro, indicating activation of the 5-ht autoreceptor. |
1989-04-27 |
2023-08-11 |
rat |