| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F Passarelli, T Costa, O F Almeid. Pertussis toxin inactivates the presynaptic serotonin autoreceptor in the hippocampus. European journal of pharmacology. vol 155. issue 3. 1989-04-27. PMID:3234488. |
it is thus concluded that the 5-ht autoreceptor in the hippocampus is coupled to g proteins. |
1989-04-27 |
2023-08-11 |
rat |
| B C Hiner, M D Mauk, S J Peroutka, J D Kocsi. Buspirone, 8-OH-DPAT and ipsapirone: effects on hippocampal cerebellar and sciatic fiber excitability. Brain research. vol 461. issue 1. 1989-04-04. PMID:2906267. |
the effects of serotonin (5-hydroxytryptamine; 5-ht), and the novel anxiolytics buspirone, 8-oh-dpat (8-hydroxy-2-[n,n-dipropylamino]-tetralin) and ipsapirone (tvxq 7821, 2-[4-[4-[2-pyrimidinyl]-1-piperazinyl] butyl]-1,2-benzisothiazol-3[2h]one-1,1-dioxide-hydrochloride) on fiber excitability were studied in three axon systems; hippocampal schaffer collateral fibers, cerebellar parallel fibers, and sciatic nerves. |
1989-04-04 |
2023-08-11 |
rat |
| D D Mousseau, A J Greensha. Chronic effects of clomipramine and clorgyline on regional levels of brain amines and acid metabolites in rats. Journal of neural transmission. vol 75. issue 1. 1989-03-29. PMID:2465373. |
the specificity of effects of cmi for 5-ht was maintained in all brain regions except the hippocampus and frontal cortex. |
1989-03-29 |
2023-08-11 |
rat |
| D L DeHaven-Hudkins, D W Schulz, T J Walsh, R B Mailma. Responses of dopaminergic and serotonergic systems to triethyllead intoxication. Neurotoxicology and teratology. vol 10. issue 4. 1989-03-29. PMID:2465482. |
administration of a single dose of tel chloride (7.88 mg/kg, sc) to male fischer-344 rats decreased the concentrations of dopamine in hippocampus, and of serotonin in olfactory tubercle, at day 7 posttreatment. |
1989-03-29 |
2023-08-11 |
rat |
| K Ohi, S Hayashi, K Takahash. Development of circadian rhythms in rats with lesions of serotonergic system. Physiology & behavior. vol 44. issue 3. 1989-03-23. PMID:3222362. |
the reductions in serotonin content induced by two manipulations with mrl and dht were 41% and 100% in the striatum, 40% and 66% in the hypothalamus, and 62% and 88% in the hippocampus, respectively. |
1989-03-23 |
2023-08-11 |
rat |
| S Stancheva, V V Petko. Effects of chronic diazepam and medazepam treatment on the level of biogenic monoamines in different rat brain areas. Acta physiologica et pharmacologica Bulgarica. vol 14. issue 3. 1989-03-17. PMID:2906206. |
both benzodiazepines provoked a significant increase in the hippocampal 5-ht level, which could be attributed to the antianxiety effect of these drugs. |
1989-03-17 |
2023-08-11 |
rat |
| B J Logan, R Laverty, W D Sanderson, Y B Ye. Differences between rats and mice in MDMA (methylenedioxymethylamphetamine) neurotoxicity. European journal of pharmacology. vol 152. issue 3. 1989-03-16. PMID:2906000. |
caused a fall 3 h after injection in the content of 5-hydroxytryptamine (5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) in cortex, a fall in noradrenaline in hippocampus and cerebellum, and a rise in dopamine (da) but fall in dihydroxyphenylacetic acid (dopac) in striatum. |
1989-03-16 |
2023-08-11 |
mouse |
| T L Casebolt, R S Jop. Long-term lithium treatment selectively reduces receptor-coupled inositol phospholipid hydrolysis in rat brain. Biological psychiatry. vol 25. issue 3. 1989-03-15. PMID:2536562. |
after long-term lithium treatment, the response to serotonin was reduced in the hippocampus and striatum, but not the cortex, and the carbachol-induced response was only reduced in the striatum. |
1989-03-15 |
2023-08-11 |
rat |
| R W Fuller, K W Perr. Effects of buspirone and its metabolite, 1-(2-pyrimidinyl)piperazine, on brain monoamines and their metabolites in rats. The Journal of pharmacology and experimental therapeutics. vol 248. issue 1. 1989-03-03. PMID:2521515. |
the decrease was due apparently to a reduced turnover of serotonin; the accumulation of 5-hydroxytryptophan after decarboxylase inhibition was also suppressed by buspirone, not only in hypothalamus but also in brain stem, hippocampus and striatum. |
1989-03-03 |
2023-08-11 |
rat |
| F Passarelli, T Cost. Mu and delta opioid receptors inhibit serotonin release in rat hippocampus. The Journal of pharmacology and experimental therapeutics. vol 248. issue 1. 1989-03-03. PMID:2536429. |
mu and delta opioid receptors inhibit serotonin release in rat hippocampus. |
1989-03-03 |
2023-08-11 |
rat |
| F Passarelli, T Cost. Mu and delta opioid receptors inhibit serotonin release in rat hippocampus. The Journal of pharmacology and experimental therapeutics. vol 248. issue 1. 1989-03-03. PMID:2536429. |
we studied the influence of opioid agonists on the release of serotonin (5-ht) elicited by k+ (20 mm) in superfused slices of rat hippocampus. |
1989-03-03 |
2023-08-11 |
rat |
| F Passarelli, T Cost. Mu and delta opioid receptors inhibit serotonin release in rat hippocampus. The Journal of pharmacology and experimental therapeutics. vol 248. issue 1. 1989-03-03. PMID:2536429. |
treatment of hippocampal slices with pertussis toxin did not alter the k+-evoked release of 5-ht but abolished the inhibitory effect of both dago and dpdpe. |
1989-03-03 |
2023-08-11 |
rat |
| C J Fowler, G Thorell, E Sundström, T Arche. Norepinephrine-stimulated inositol phospholipid breakdown in the rat cerebral cortex following serotoninergic lesion. Journal of neural transmission. vol 73. issue 3. 1989-02-23. PMID:2850349. |
treatment of rats with 5,7-dihydroxytryptamine and dsp4 produced selective depletions of serotonin (79-95%) and ne (69-85%), respectively, in cortical and hippocampal brain regions. |
1989-02-23 |
2023-08-11 |
rat |
| P Blier, C de Montign. Modification of 5-HT neuron properties by sustained administration of the 5-HT1A agonist gepirone: electrophysiological studies in the rat brain. Synapse (New York, N.Y.). vol 1. issue 5. 1989-02-23. PMID:2905533. |
the responsiveness of postsynaptic dorsal hippocampus pyramidal neurons to 5-ht, 8-oh-dpat, and gepirone was not altered by the 14-day gepirone treatment. |
1989-02-23 |
2023-08-11 |
rat |
| P H Desan, W W Woodmansee, S M Ryan, T K Smock, S F Maie. Monoamine neurotransmitters and metabolites during the estrous cycle, pregnancy, and the postpartum period. Pharmacology, biochemistry, and behavior. vol 30. issue 3. 1989-02-23. PMID:3211964. |
since monoamine systems have been implicated in the control of these behaviors, the present study examined the tissue concentrations of norepinephrine (ne), dopamine (da), and serotonin (5ht) and their primary metabolites dihydroxyphenylglycol (dhpg), 3-methoxy-4-hydroxyphenylglycol (mhpg), 3,4-dihydroxyphenylacetic acid (dopac), and 5-hydroxyindoleacetic acid (5hiaa) in the anterior cerebral cortex, hippocampus, and cerebellum during the estrous cycle, late pregnancy, and the early postpartum period. |
1989-02-23 |
2023-08-11 |
rat |
| D Wirtshafter, M A Klitenick, K E Asi. Is dopamine involved in the hyperactivity produced by injections of muscimol into the median raphe nucleus? Pharmacology, biochemistry, and behavior. vol 30. issue 3. 1989-02-23. PMID:3211966. |
muscimol injections resulted in pronounced hyperactivity which was accompanied by a decrease in serotonin metabolism within the hippocampus and an increase in dopamine metabolism within the nucleus accumbens. |
1989-02-23 |
2023-08-11 |
Not clear |
| A Daszuta, R E Strecker, P Brundin, A Björklun. Serotonin neurons grafted to the adult rat hippocampus. I. Time course of growth as studied by immunohistochemistry and biochemistry. Brain research. vol 458. issue 1. 1989-02-22. PMID:2463040. |
serotonin neurons grafted to the adult rat hippocampus. |
1989-02-22 |
2023-08-11 |
rat |
| A Daszuta, R E Strecker, P Brundin, A Björklun. Serotonin neurons grafted to the adult rat hippocampus. I. Time course of growth as studied by immunohistochemistry and biochemistry. Brain research. vol 458. issue 1. 1989-02-22. PMID:2463040. |
a regression analysis revealed a significant inverse correlation between the hippocampal 5-ht concentration and the 5-hiaa:5-ht ratio in the graft-reinnervated hippocampal formation. |
1989-02-22 |
2023-08-11 |
rat |
| G Lombardi, M Beni, V Carla', G Toffano, F Moron. Differential actions of neurotrophic factors on lesion-induced damage of the serotonergic neurons projecting to the hippocampus. Brain research. vol 458. issue 2. 1989-02-22. PMID:2463051. |
this lesion selectively reduced the content of 5-ht and 5-hiaa in the ipsilateral hippocampus. |
1989-02-22 |
2023-08-11 |
rat |
| G Lombardi, M Beni, V Carla', G Toffano, F Moron. Differential actions of neurotrophic factors on lesion-induced damage of the serotonergic neurons projecting to the hippocampus. Brain research. vol 458. issue 2. 1989-02-22. PMID:2463051. |
daily intraperitoneal injection of gm1-ganglioside (30 mg/kg/day for 6-14 days) significantly reduced the injury-induced loss of hippocampal 5-ht and 5-hiaa content. |
1989-02-22 |
2023-08-11 |
rat |