| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Mocaër, M C Rettori, A Kamou. Pharmacological antidepressive effects and tianeptine-induced 5-HT uptake increase. Clinical neuropharmacology. vol 11 Suppl 2. 1988-12-20. PMID:3180116. |
tianeptine, in contrast to tricyclic antidepressants which inhibit 5-ht uptake, stimulates serotonin uptake ex vivo in the rat brain (cortex, hippocampus) and rat as well as human platelets following both acute and chronic administration. |
1988-12-20 |
2023-08-11 |
mouse |
| E Mocaër, M C Rettori, A Kamou. Pharmacological antidepressive effects and tianeptine-induced 5-HT uptake increase. Clinical neuropharmacology. vol 11 Suppl 2. 1988-12-20. PMID:3180116. |
tianeptine increases the firing rate of hippocampus pyramidal cells which could be consistent with tianeptine-induced serotonin uptake stimulation. |
1988-12-20 |
2023-08-11 |
mouse |
| T Kubo, S Shibanoki, A Matsumoto, K Tsuda, K Ishikaw. Portacaval anastomosis attenuates the impairing effect of cyproheptadine on avoidance learning in rats--an involvement of the serotonergic system. Behavioural brain research. vol 30. issue 3. 1988-12-06. PMID:3178999. |
significant increases in the concentration of 5-hydroxyindoleacetic acid, a metabolite of 5-hydroxytryptamine (5-ht), in all regions examined and the turnover rate of this indoleamine transmitter in the hippocampus, hypothalamus, midbrain and medulla oblongata were observed in pca rats in comparison with sham-operated controls. |
1988-12-06 |
2023-08-11 |
rat |
| M A Harrington, D Oksenberg, S J Peroutk. 5-Hydroxytryptamine1A receptors are linked to a Gi-adenylate cyclase complex in rat hippocampus. European journal of pharmacology. vol 154. issue 1. 1988-12-01. PMID:2972552. |
the ability of 5-hydroxytryptamine (5-ht) and the 5-ht1a selective agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat) to modulate adenylate cyclase activity was measured in rat hippocampus. |
1988-12-01 |
2023-08-11 |
rat |
| P Nencini, W L Woolverton, L S Seide. Enhancement of morphine-induced analgesia after repeated injections of methylenedioxymethamphetamine. Brain research. vol 457. issue 1. 1988-11-23. PMID:2901895. |
mdma selectively depleted 5-ht in the cortex, hippocampus, striatum, brainstem and in the cervical portion of spinal cord. |
1988-11-23 |
2023-08-11 |
rat |
| R Bouhelal, L Smounya, J Bockaer. 5-HT1B receptors are negatively coupled with adenylate cyclase in rat substantia nigra. European journal of pharmacology. vol 151. issue 2. 1988-11-23. PMID:2971554. |
cgs 120 66b was almost as potent (ec50 = 100 nm) as 5-ht to inhibit the forskolin-stimulated adenylate cyclase in rat substantia nigra homogenates whereas this preferential 5-ht1b agonist was 100 times less potent than 5-ht in hippocampus guinea pig homogenates. |
1988-11-23 |
2023-08-11 |
rat |
| A Adell, R Trullas, E Gelp. Time course of changes in serotonin and noradrenaline in rat brain after predictable or unpredictable shock. Brain research. vol 459. issue 1. 1988-11-21. PMID:2458804. |
5-ht metabolism expressed as the 5-hiaa/5-ht ratio, was significantly increased 30 min after predictable shock in all regions except the locus coeruleus and hippocampus. |
1988-11-21 |
2023-08-11 |
rat |
| b' C Su\\xc3\\xb1ol, J M Tusell, E Gelp\\xc3\\xad, E Rodr\\xc3\\xadguez-Farr\\xc3\\xa. Regional concentrations of GABA, serotonin and noradrenaline in brain at onset of seizures induced by lindane (gamma-hexachlorocyclohexane). Neuropharmacology. vol 27. issue 7. 1988-10-24. PMID:2458533.' |
the inhibitory neurotransmitter gamma-aminobutyric acid (gaba) and the biogenic amines noradrenaline (na) and serotonin (5-ht), as well as its corresponding acidic metabolite, were determined by high performance liquid chromatography with fluorimetric or electrochemical detection in different areas of the brain: hippocampus, mesencephalon, colliculi, frontal cortex, parietal cortex, striatum and thalamus. |
1988-10-24 |
2023-08-11 |
Not clear |
| M S Kleven, C R Schuster, L S Seide. Effect of depletion of brain serotonin by repeated fenfluramine on neurochemical and anorectic effects of acute fenfluramine. The Journal of pharmacology and experimental therapeutics. vol 246. issue 3. 1988-10-21. PMID:2458447. |
acute administration of fenfluramine produced a dose-dependent decrease in milk intake and 5-ht and 5-hydroxyindoleacetic acid (5-hiaa) levels in cortex, hypothalamus and hippocampus. |
1988-10-21 |
2023-08-11 |
rat |
| M S Kleven, C R Schuster, L S Seide. Effect of depletion of brain serotonin by repeated fenfluramine on neurochemical and anorectic effects of acute fenfluramine. The Journal of pharmacology and experimental therapeutics. vol 246. issue 3. 1988-10-21. PMID:2458447. |
levels of 5-ht and 5-hiaa in somatosensory cortex, hypothalamus, striatum and hippocampus were depleted significantly 2 weeks after the last daily fenfluramine injection. |
1988-10-21 |
2023-08-11 |
rat |
| N Roper. Inhibitory action of serotonin in CA1 hippocampal neurons in vitro. Neuroscience. vol 26. issue 1. 1988-10-20. PMID:2843792. |
inhibitory action of serotonin in ca1 hippocampal neurons in vitro. |
1988-10-20 |
2023-08-11 |
rat |
| N Roper. Inhibitory action of serotonin in CA1 hippocampal neurons in vitro. Neuroscience. vol 26. issue 1. 1988-10-20. PMID:2843792. |
the ionic mechanism of the inhibitory effect of serotonin was investigated in vitro in the ca1 region of the rat hippocampus by extra- and intracellular recordings. |
1988-10-20 |
2023-08-11 |
rat |
| G Szabó, G L Kovács, G Telegd. Brain monoamines are involved in mediating the action of neurohypophyseal peptide hormones on ethanol tolerance. Acta physiologica Hungarica. vol 71. issue 3. 1988-10-18. PMID:3421121. |
in the peptide-pretreated animals the na level was increased in the hypothalamus, the da level in the striatum, and the 5-ht level in the hippocampus and striatum. |
1988-10-18 |
2023-08-11 |
mouse |
| G S Alemà, S Maccari, M A Micci, F R Patacchiol. Hippocampal serotonin in the regulation of the hypothalamo-pituitary-adrenocortical axis (HPAA) stress response. Pharmacological research communications. vol 20. issue 5. 1988-10-17. PMID:2458602. |
hippocampal serotonin in the regulation of the hypothalamo-pituitary-adrenocortical axis (hpaa) stress response. |
1988-10-17 |
2023-08-11 |
Not clear |
| M Muramatsu, J Tamaki-Ohashi, C Usuki, H Araki, H Aihar. Serotonin-2 receptor-mediated regulation of release of acetylcholine by minaprine in cholinergic nerve terminal of hippocampus of rat. Neuropharmacology. vol 27. issue 6. 1988-10-17. PMID:3419543. |
5-hydroxytryptamine (5-ht) inhibited the k+-induced release of [3h]acetylcholine [( 3h]ach) from slices of the hippocampus of the rat, dose-dependently. |
1988-10-17 |
2023-08-11 |
rat |
| M Muramatsu, J Tamaki-Ohashi, C Usuki, H Araki, H Aihar. Serotonin-2 receptor-mediated regulation of release of acetylcholine by minaprine in cholinergic nerve terminal of hippocampus of rat. Neuropharmacology. vol 27. issue 6. 1988-10-17. PMID:3419543. |
minaprine inhibited the bindings of [3h]5-ht, [3h]8-oh-dpat and [3h]ketanserin in the hippocampus. |
1988-10-17 |
2023-08-11 |
rat |
| M Muramatsu, J Tamaki-Ohashi, C Usuki, H Araki, H Aihar. Serotonin-2 receptor-mediated regulation of release of acetylcholine by minaprine in cholinergic nerve terminal of hippocampus of rat. Neuropharmacology. vol 27. issue 6. 1988-10-17. PMID:3419543. |
by electrolytic lesioning of the medial septum, the k+-induced release of [3h]ach from the slices of hippocampus was significantly reduced and the release was no longer inhibited by 5-ht. |
1988-10-17 |
2023-08-11 |
rat |
| M Muramatsu, J Tamaki-Ohashi, C Usuki, H Araki, H Aihar. Serotonin-2 receptor-mediated regulation of release of acetylcholine by minaprine in cholinergic nerve terminal of hippocampus of rat. Neuropharmacology. vol 27. issue 6. 1988-10-17. PMID:3419543. |
the lesioning significantly decreased the binding of [3h]ketanserin in the hippocampus, with hardly any reduction in the binding of [3h]5-ht and [3h]8-oh-dpat. |
1988-10-17 |
2023-08-11 |
rat |
| M Martire, P Navarra, G Pistritto, P Prezios. Adrenal steroid-induced changes in serotonin receptors in rat hippocampus and hypothalamus. Pharmacological research communications. vol 20. issue 5. 1988-10-17. PMID:3420146. |
adrenal steroid-induced changes in serotonin receptors in rat hippocampus and hypothalamus. |
1988-10-17 |
2023-08-11 |
rat |
| E O'Hearn, G Battaglia, E B De Souza, M J Kuhar, M E Mollive. Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 8. issue 8. 1988-10-07. PMID:2457659. |
regional differences in drug toxicity are exemplified by partial sparing of 5-ht axons in hippocampus, lateral hypothalamus, basal forebrain, and in some areas of neocortex. |
1988-10-07 |
2023-08-11 |
rat |