| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J C Soto, E J Marc. Measurement of 5-hydroxytryptamine turnover rate in rat cerebral arteries. The Journal of pharmacy and pharmacology. vol 40. issue 3. 1988-08-18. PMID:2455784. |
in the hippocampus, pargyline induced a lineal accumulation of 5-ht throughout the experiment as well as an exponential decay of the 5-hiaa concentration. |
1988-08-18 |
2023-08-11 |
rat |
| M Beni, D E Pellegrini-Giampietro, F Moron. A new endogenous anxiolytic agent: L-pyroglutamic acid. Fundamental & clinical pharmacology. vol 2. issue 2. 1988-08-17. PMID:2455680. |
furthermore, anxiolytic doses of the amino acid did not change the content of 5-hydroxytryptamine (5-ht) or of 5-hydroxyindoleacetic acid (5-hiaa) in the rat cortex and hippocampus. |
1988-08-17 |
2023-08-11 |
rat |
| Y Chaput, C de Montign. Effects of the 5-hydroxytryptamine receptor antagonist, BMY 7378, on 5-hydroxytryptamine neurotransmission: electrophysiological studies in the rat central nervous system. The Journal of pharmacology and experimental therapeutics. vol 246. issue 1. 1988-08-17. PMID:2839669. |
in the present electrophysiological studies, the effects of the putative 5-hydroxytryptamine (5-ht) receptor antagonist, bmy 7378, on the response of dorsal raphe nucleus 5-ht neurons and of ca3 dorsal hippocampus pyramidal neurons to 5-ht and 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat) were investigated in chloral hydrate-anesthetized rats. |
1988-08-17 |
2023-08-11 |
rat |
| Y Chaput, C de Montign. Effects of the 5-hydroxytryptamine receptor antagonist, BMY 7378, on 5-hydroxytryptamine neurotransmission: electrophysiological studies in the rat central nervous system. The Journal of pharmacology and experimental therapeutics. vol 246. issue 1. 1988-08-17. PMID:2839669. |
bmy 7378 reduced the effectiveness of 8-oh-dpat, but not that of 5-ht, in depressing 5-ht neuron firing rate, whereas that of both agonists was reduced by concurrent application of bmy 7378 in the hippocampus. |
1988-08-17 |
2023-08-11 |
rat |
| M R Pranzatelli, A Dailey, S Markus. The regulation of TRH and serotonin receptors: chronic TRH and analog administration in the rat. Journal of receptor research. vol 8. issue 5. 1988-08-17. PMID:2839679. |
5-ht and ne concentrations measured by hplc were not altered in brainstem or hippocampus. |
1988-08-17 |
2023-08-11 |
rat |
| G A Foster, M Schultzberg, F H Gage, A Björklund, T Hökfelt, A C Cuello, A A Verhofstad, T J Visser, P C Emso. Transmitter expression and morphological development of embryonic medullary and mesencephalic raphé neurones after transplantation to the adult rat central nervous system. II. Grafts to the hippocampus. Experimental brain research. vol 70. issue 2. 1988-07-29. PMID:2454837. |
a rich outgrowth of 5ht-immunoreactive varicose processes was evident, with the same pattern as the 5ht innervation by the mesencephalic raphé grafts, and as in the normal hippocampus. |
1988-07-29 |
2023-08-11 |
rat |
| N A Otmakho. [Action of mediators on pyramidal and nonpyramidal neurons in slices of the guinea pig hippocampus]. Neirofiziologiia = Neurophysiology. vol 20. issue 1. 1988-07-26. PMID:2898102. |
effects of acetylcholine (ach), norepinephrine (ne), 5-hydroxytryptamine (5-ht) and gamma-aminobutyric acid (gaba) on the background activity were tested in the field ca3 in the guinea pig hippocampal slices. |
1988-07-26 |
2023-08-11 |
Not clear |
| S L Carlson, D L Felten, S Livnat, S Y Felte. Alterations of monoamines in specific central autonomic nuclei following immunization in mice. Brain, behavior, and immunity. vol 1. issue 1. 1988-07-22. PMID:3451782. |
serotonin was decreased in the hippocampus on day 2, was decreased in the pvn and supraoptic nucleus on day 4, and was increased in the nucleus tractus solitarius (nts) on day 2. |
1988-07-22 |
2023-08-11 |
mouse |
| M E Newman, B Lere. Chronic electroconvulsive shock and desimipramine reduce the degree of inhibition by 5-HT and carbachol of forskolin-stimulated adenylate cyclase in rat hippocampal membranes. European journal of pharmacology. vol 148. issue 2. 1988-07-15. PMID:3378574. |
chronic electroconvulsive shock and desimipramine reduce the degree of inhibition by 5-ht and carbachol of forskolin-stimulated adenylate cyclase in rat hippocampal membranes. |
1988-07-15 |
2023-08-11 |
rat |
| M E Newman, B Lere. Chronic electroconvulsive shock and desimipramine reduce the degree of inhibition by 5-HT and carbachol of forskolin-stimulated adenylate cyclase in rat hippocampal membranes. European journal of pharmacology. vol 148. issue 2. 1988-07-15. PMID:3378574. |
the degree of inhibition of forskolin-stimulated adenylate cyclase activity by 5-ht and by carbachol in hippocampal membranes was significantly reduced after administration of either chronic ecs (10 days) or desimipramine (10 mg/kg i.p. |
1988-07-15 |
2023-08-11 |
rat |
| M Santiago, A Machado, F Reinoso-Suárez, J Can. Changes in biogenic amines in rat hippocampus during development and aging. Life sciences. vol 42. issue 24. 1988-07-08. PMID:2453775. |
the effects of postnatal development and aging on the concentration of dopamine, noradrenaline, serotonin and their principle metabolites have been studied in the hippocampus of the rat. |
1988-07-08 |
2023-08-11 |
rat |
| M Santiago, A Machado, F Reinoso-Suárez, J Can. Changes in biogenic amines in rat hippocampus during development and aging. Life sciences. vol 42. issue 24. 1988-07-08. PMID:2453775. |
these findings led to the conclusion that the neurotransmitters: noradrenaline and serotonin, are developed in the hippocampus during the first three months. |
1988-07-08 |
2023-08-11 |
rat |
| S E Robinson, K L Hambrech. Effect of intrastriatal injection of soman on acetylcholine, dopamine and serotonin metabolism. Life sciences. vol 42. issue 23. 1988-07-01. PMID:3374262. |
however, serotonin (5-ht) metabolism appears to be affected in the cortex, hippocampus and medulla/pons following intrastriatal injection of soman. |
1988-07-01 |
2023-08-11 |
rat |
| P C Bickford-Wimer, J A Miller, R Freedman, G M Ros. Age-related reduction in responses of rat hippocampal neurons to locally applied monoamines. Neurobiology of aging. vol 9. issue 2. 1988-06-24. PMID:3374734. |
taken together these data indicate that there is a progressive age-related decline in the postsynaptic response to ne and 5ht in the rodent hippocampus. |
1988-06-24 |
2023-08-11 |
rat |
| P D Hrdin. Sodium-dependent [3H]imipramine binding in rat hippocampus and its relationship to serotonin uptake. Canadian journal of physiology and pharmacology. vol 65. issue 12. 1988-06-20. PMID:2452679. |
sodium-dependent [3h]imipramine binding in rat hippocampus and its relationship to serotonin uptake. |
1988-06-20 |
2023-08-11 |
rat |
| P D Hrdin. Sodium-dependent [3H]imipramine binding in rat hippocampus and its relationship to serotonin uptake. Canadian journal of physiology and pharmacology. vol 65. issue 12. 1988-06-20. PMID:2452679. |
the relationship of [3h]imipramine recognition sites and serotonergic function was investigated by simultaneously determining the desipramine-defined and sodium-dependent components of [3h]imipramine binding and the serotonin levels and uptake in hippocampus of rats without and with selective lesion of serotonergic neurons with 5,7-dihydroxytryptamine. |
1988-06-20 |
2023-08-11 |
rat |
| P D Hrdin. Sodium-dependent [3H]imipramine binding in rat hippocampus and its relationship to serotonin uptake. Canadian journal of physiology and pharmacology. vol 65. issue 12. 1988-06-20. PMID:2452679. |
5,7-dihydroxytryptamine treatment resulted in marked reduction of hippocampal serotonin concentration and uptake without any changes in norepinephrine levels. |
1988-06-20 |
2023-08-11 |
rat |
| T Tsubokawa, Y Katayama, S Miyazaki, H Ogawa, M Iwasaki, S Shibanoki, K Ishikaw. Supranormal levels of serotonin and its metabolite after raphe cell transplantation in serotonin-denervated rat hippocampus. Brain research bulletin. vol 20. issue 3. 1988-06-16. PMID:2452672. |
supranormal levels of serotonin and its metabolite after raphe cell transplantation in serotonin-denervated rat hippocampus. |
1988-06-16 |
2023-08-11 |
rat |
| T Tsubokawa, Y Katayama, S Miyazaki, H Ogawa, M Iwasaki, S Shibanoki, K Ishikaw. Supranormal levels of serotonin and its metabolite after raphe cell transplantation in serotonin-denervated rat hippocampus. Brain research bulletin. vol 20. issue 3. 1988-06-16. PMID:2452672. |
transplantation of fetal raphe cells (14 days of gestation) into the adult rat hippocampus, 2 weeks following serotonin (5-ht)-denervation with intracisternal injection of 5,7-dihydroxytryptamine, can restore 5-ht and 5-hydroxyindoleacetic acid (5-hiaa) levels in the hippocampus to far beyond normal values. |
1988-06-16 |
2023-08-11 |
rat |
| T Tsubokawa, Y Katayama, S Miyazaki, H Ogawa, M Iwasaki, S Shibanoki, K Ishikaw. Supranormal levels of serotonin and its metabolite after raphe cell transplantation in serotonin-denervated rat hippocampus. Brain research bulletin. vol 20. issue 3. 1988-06-16. PMID:2452672. |
transplantation into the unilateral hippocampus produces asymmetrical turning behavior after administration of the 5-ht releasor, p-chloroamphetamine (ip), comparable to the behavior reported for rats with 5-ht denervation of the unilateral hippocampus. |
1988-06-16 |
2023-08-11 |
rat |