| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Sharp, S R Bramwell, D Clark, D G Grahame-Smit. In vivo measurement of extracellular 5-hydroxytryptamine in hippocampus of the anaesthetized rat using microdialysis: changes in relation to 5-hydroxytryptaminergic neuronal activity. Journal of neurochemistry. vol 53. issue 1. 1989-07-13. PMID:2470860. |
injection of the 5-ht1a agonist 8-hydroxy-2-(di-n-propylamino)tetralin (0.5 and 2.5 micrograms) into the dorsal raphe nucleus caused a dose-related fall in hippocampal output of 5-ht compared to saline-injected controls. |
1989-07-13 |
2023-08-11 |
rat |
| T Sharp, S R Bramwell, D Clark, D G Grahame-Smit. In vivo measurement of extracellular 5-hydroxytryptamine in hippocampus of the anaesthetized rat using microdialysis: changes in relation to 5-hydroxytryptaminergic neuronal activity. Journal of neurochemistry. vol 53. issue 1. 1989-07-13. PMID:2470860. |
we conclude from these data that the spontaneous output of endogenous 5-ht into hippocampal dialysates, measured under our experimental conditions, predominantly originates from central 5-ht neurones and changes in accordance with their electrical activity. |
1989-07-13 |
2023-08-11 |
rat |
| T Sharp, G A Foste. In vivo measurement using microdialysis of the release and metabolism of 5-hydroxytryptamine in raphe neurones grafted to the rat hippocampus. Journal of neurochemistry. vol 53. issue 1. 1989-07-13. PMID:2470862. |
in vivo measurement using microdialysis of the release and metabolism of 5-hydroxytryptamine in raphe neurones grafted to the rat hippocampus. |
1989-07-13 |
2023-08-11 |
rat |
| T Sharp, G A Foste. In vivo measurement using microdialysis of the release and metabolism of 5-hydroxytryptamine in raphe neurones grafted to the rat hippocampus. Journal of neurochemistry. vol 53. issue 1. 1989-07-13. PMID:2470862. |
the overflow and metabolism of serotonin (5-hydroxytryptamine; 5-ht) from transplants of embryonic medullary and mesencephalic raphe neurones in the previously 5-ht-denervated hippocampus have been analyzed in vivo using intracerebral dialysis. |
1989-07-13 |
2023-08-11 |
rat |
| T Sharp, G A Foste. In vivo measurement using microdialysis of the release and metabolism of 5-hydroxytryptamine in raphe neurones grafted to the rat hippocampus. Journal of neurochemistry. vol 53. issue 1. 1989-07-13. PMID:2470862. |
nonetheless, both basal and potassium-stimulated levels of 5-ht in the dialysates were restored to approximately normal after transplantation of medullary raphe cells, whereas mesencephalic implants resulted in over twice the 5-ht output observed in control hippocampus. |
1989-07-13 |
2023-08-11 |
rat |
| M Johnson, D M Stone, L G Bush, G R Hanson, J W Gib. Glucocorticoids and 3,4-methylenedioxymethamphetamine (MDMA)-induced neurotoxicity. European journal of pharmacology. vol 161. issue 2-3. 1989-07-07. PMID:2470597. |
the long-term mdma-induced decreases in hippocampal serotonin (5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) concentrations were similarly affected by cort replacement. |
1989-07-07 |
2023-08-11 |
Not clear |
| M Johnson, D M Stone, L G Bush, G R Hanson, J W Gib. Glucocorticoids and 3,4-methylenedioxymethamphetamine (MDMA)-induced neurotoxicity. European journal of pharmacology. vol 161. issue 2-3. 1989-07-07. PMID:2470597. |
however, adx did not alter the short-term decline in hippocampal tph activity and 5-ht concentrations measured 3 h after a single dose of mdma (10 mg/kg s.c.). |
1989-07-07 |
2023-08-11 |
Not clear |
| A Baskys, C E Niesen, M F Davies, P L Carle. Modulatory actions of serotonin on ionic conductances of hippocampal dentate granule cells. Neuroscience. vol 29. issue 2. 1989-07-07. PMID:2471114. |
modulatory actions of serotonin on ionic conductances of hippocampal dentate granule cells. |
1989-07-07 |
2023-08-11 |
Not clear |
| M F Beal, M F Mazurek, D W Ellison, N W Kowall, P R Solomon, W W Pendlebur. Neurochemical characteristics of aluminum-induced neurofibrillary degeneration in rabbits. Neuroscience. vol 29. issue 2. 1989-07-07. PMID:2566953. |
there was a significant reduction in choline acetyltransferase activity in entorhinal cortex and hippocampus as well as significant reductions in cortical concentrations of serotonin and norepinephrine in the aluminum-treated rabbits. |
1989-07-07 |
2023-08-11 |
Not clear |
| A J Greenshaw, T S Rao, A J Nazarali, G B Baker, R T Coutt. Chronic effects of tranylcypromine and 4-fluorotranylcypromine on regional brain monoamine metabolism in rats: a comparison with clorgyline. Biological psychiatry. vol 25. issue 8. 1989-07-06. PMID:2470425. |
levels of noradrenaline, 5-hydroxytryptamine, dopamine, and of the acid metabolites 5-hydroxyindole-3-acetic acid, 3,4-dihydroxyphenylacetic acid, and homovanillic acid were measured in the frontal cortex, nucleus accumbens, caudate nucleus, hippocampus, and hypothalamus. |
1989-07-06 |
2023-08-11 |
rat |
| F Godefroy, M H Bassant, J Weil-Fugazza, Y Lamou. Age-related changes in dopaminergic and serotonergic indices in the rat forebrain. Neurobiology of aging. vol 10. issue 2. 1989-06-26. PMID:2471092. |
age-related changes in the content of dopamine (da), homovanillic acid (hva), dihydroxyphenylacetic acid (dopac), 3-methoxytyramine (3-mt), serotonin (5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) in anterior cerebral cortex, hippocampus and striatum of the rat have been investigated using hplc with electrochemical detection. |
1989-06-26 |
2023-08-11 |
rat |
| b' Y Hong, K Krnjevi\\xc4\\x8. Serotonin blocks the facilitatory action of muscarinic and nicotinic agents in the hippocampus in vivo. Canadian journal of physiology and pharmacology. vol 67. issue 1. 1989-06-16. PMID:2653594.' |
serotonin blocks the facilitatory action of muscarinic and nicotinic agents in the hippocampus in vivo. |
1989-06-16 |
2023-08-11 |
rat |
| b' Y Hong, K Krnjevi\\xc4\\x8. Serotonin blocks the facilitatory action of muscarinic and nicotinic agents in the hippocampus in vivo. Canadian journal of physiology and pharmacology. vol 67. issue 1. 1989-06-16. PMID:2653594.' |
the inhibitory effect of serotonin, released iontophoretically, on acetylcholine-induced facilitation of population spikes evoked by fimbria-commissural stimulation was studied in the ca1 region of rat hippocampus in vivo. |
1989-06-16 |
2023-08-11 |
rat |
| J M Barnes, N M Barnes, B Costall, R J Naylor, M B Tyer. 5-HT3 receptors mediate inhibition of acetylcholine release in cortical tissue. Nature. vol 338. issue 6218. 1989-06-09. PMID:2524005. |
depleting 5-ht by inhibiting synthesis or by destroying the neurons containing 5-ht potentiates acetylcholine release, and increases acetylcholine turnover in the cerebral cortex and hippocampus. |
1989-06-09 |
2023-08-11 |
Not clear |
| E Gottberg, L Grondin, T A Reade. Acute effects of lithium on catecholamines, serotonin, and their major metabolites in discrete brain regions. Journal of neuroscience research. vol 22. issue 3. 1989-06-06. PMID:2709448. |
the acute effects of lithium on the central catecholamine and serotonin systems were investigated in well-defined cortical areas in the rat: the anterior cingulate cortex (cin), the piriform-entorhinal region (pien), and the primary visual area (vis) as well as in the hippocampus (hip), the neostriatum (cpu; caudateputamen), and the olfactory bulbs (obs). |
1989-06-06 |
2023-08-11 |
rat |
| F Okada, Y Tokumitsu, Y Nomur. Pertussis toxin attenuates 5-hydroxytryptamine1A receptor-mediated inhibition of forskolin-stimulated adenylate cyclase activity in rat hippocampal membranes. Journal of neurochemistry. vol 52. issue 5. 1989-06-02. PMID:2523468. |
the inhibition of forskolin-stimulated adenylate cyclase activity by 5-hydroxytryptamine (5-ht) receptor agonists was measured in rat hippocampal membranes isolated from animals treated with vehicle or islet-activating protein (iap; pertussis toxin). |
1989-06-02 |
2023-08-11 |
rat |
| D Wirtshafter, R Trifunovic, J C Kreb. Behavioral and biochemical evidence for a functional role of excitatory amino acids in the median raphe nucleus. Brain research. vol 482. issue 2. 1989-06-01. PMID:2565141. |
injections of 2-apv into the median raphe were also shown to result in a reduction of serotonin metabolism within the hippocampus and an increase in dopamine metabolism within the nucleus accumbens and the magnitude of both of these effects was positively correlated with the behavioral responses to the injections. |
1989-06-01 |
2023-08-11 |
human |
| T J Feuerstein, K I Bär, C H Lückin. Activation of A1 adenosine receptors decreases the release of serotonin in the rabbit hippocampus, but not in the caudate nucleus. Naunyn-Schmiedeberg's archives of pharmacology. vol 338. issue 6. 1989-05-31. PMID:3244398. |
activation of a1 adenosine receptors decreases the release of serotonin in the rabbit hippocampus, but not in the caudate nucleus. |
1989-05-31 |
2023-08-11 |
rabbit |
| T J Feuerstein, K I Bär, C H Lückin. Activation of A1 adenosine receptors decreases the release of serotonin in the rabbit hippocampus, but not in the caudate nucleus. Naunyn-Schmiedeberg's archives of pharmacology. vol 338. issue 6. 1989-05-31. PMID:3244398. |
the effects of a1 adenosine receptor ligands on the evoked release of serotonin (5-ht) were studied in slices of the hippocampus and the caudate nucleus of the rabbit, preincubated with 3h-5-ht. |
1989-05-31 |
2023-08-11 |
rabbit |
| T J Feuerstein, K I Bär, C H Lückin. Activation of A1 adenosine receptors decreases the release of serotonin in the rabbit hippocampus, but not in the caudate nucleus. Naunyn-Schmiedeberg's archives of pharmacology. vol 338. issue 6. 1989-05-31. PMID:3244398. |
when instead of electrical pulses high k+ was used to induce 5-ht release in the presence of the na+ channel blocker tetrodotoxin (ttx), which was present in order to exclude effects mediated by interneurones, cha was equally effective in the hippocampus but again failed to modify 5-ht release in the caudate nucleus. |
1989-05-31 |
2023-08-11 |
rabbit |