| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S G Beck, W P Clarke, J Goldfar. Chronic estrogen effects on 5-hydroxytryptamine-mediated responses in hippocampal pyramidal cells of female rats. Neuroscience letters. vol 106. issue 1-2. 1990-01-04. PMID:2586823. |
intracellular recording techniques were used to assess the effect of chronic estrogen treatment of ovariectomized (ovx) rats on ca1 pyramidal cell properties and serotonin (5-ht)-mediated responses in the dorsal hippocampus. |
1990-01-04 |
2023-08-11 |
rat |
| A Mørk, A Geisle. Effects of lithium ex vivo on the GTP-mediated inhibition of calcium-stimulated adenylate cyclase activity in rat brain. European journal of pharmacology. vol 168. issue 3. 1990-01-03. PMID:2583240. |
serotonin (5-ht) dose dependently reduced ca2+-stimulated adenylate cyclase activity in the hippocampus, and chronic lithium administration reduced the ability of 1 microm 5-ht to inhibit ca2+-stimulated enzyme activity. |
1990-01-03 |
2023-08-11 |
rat |
| A Mørk, A Geisle. Effects of lithium ex vivo on the GTP-mediated inhibition of calcium-stimulated adenylate cyclase activity in rat brain. European journal of pharmacology. vol 168. issue 3. 1990-01-03. PMID:2583240. |
furthermore, long-term administration of lithium could reduce the inhibitory effect of 5-ht on adenylate cyclase in the hippocampus, by influencing the inhibitory gtp-binding protein. |
1990-01-03 |
2023-08-11 |
rat |
| T A Reader, K M Dewar, L Grondi. Distribution of monoamines and metabolites in rabbit neostriatum, hippocampus and cortex. Brain research bulletin. vol 23. issue 3. 1990-01-03. PMID:2819481. |
the monoamines noradrenaline (na), dopamine (da), adrenaline (ad) and 5-hydroxytryptamine (5-ht) were assayed in the putamen (put), the lateral (lcau) and medial (mcau) portions of the caudate, the dorsal (dhip) and ventral (vhip) hippocampus, as well as in four cortical areas, i.e., anterior cingulate (cin), entorhinal-piriform (enpi), sensorimotor (ssc; somatosensory) and primary visual (vis). |
1990-01-03 |
2023-08-11 |
rabbit |
| A A Li, G J Marek, G Vosmer, L S Seide. Long-term central 5-HT depletions resulting from repeated administration of MDMA enhances the effects of single administration of MDMA on schedule-controlled behavior of rats. Pharmacology, biochemistry, and behavior. vol 33. issue 3. 1989-12-29. PMID:2573905. |
repeated administration of mdma resulted in long-term depletion of serotonin levels by 30-50% in the amygdala, neostriatum, hippocampus and the frontal cortex. |
1989-12-29 |
2023-08-11 |
rat |
| S Wieland, D Goodale, I Luck. Behavioral effects of 8-OH-DPAT: studies using the Microtaxic ventricular injector. Journal of neuroscience methods. vol 30. issue 2. 1989-12-28. PMID:2531256. |
injection of the 5-ht neurotoxin produced a 79% depletion of 5-ht in the cortex and an 86% depletion of 5-ht in the hippocampus. |
1989-12-28 |
2023-08-11 |
rat |
| M C Buhot, P Rage, L Seg. Changes in exploratory behaviour of hamsters following treatment with 8-hydroxy-2-(di-n-propylamino)tetralin. Behavioural brain research. vol 35. issue 2. 1989-12-22. PMID:2530993. |
8-oh-dpat is assumed to act on 5-ht somatodendritic autoreceptors, lowering 5-ht utilization in the hippocampus, which is the main structure implicated in spatial memory. |
1989-12-22 |
2023-08-11 |
human |
| K T Finnegan, L E DeLanney, I Irwin, G A Ricaurte, J W Langsto. The amine-depleting effects of 5,7-dihydroxytryptamine (5,7-DHT) in C57BL/6 mice do not increase with age. Brain research. vol 496. issue 1-2. 1989-12-21. PMID:2804634. |
norepinephrine and serotonin in the hippocampus were assayed 1 week after the intracerebroventricular (i.c.v.) |
1989-12-21 |
2023-08-11 |
mouse |
| J M Barnes, N M Barnes, B Costall, J W Ironside, R J Naylo. Identification and characterisation of 5-hydroxytryptamine 3 recognition sites in human brain tissue. Journal of neurochemistry. vol 53. issue 6. 1989-12-21. PMID:2809591. |
it is concluded that [3h]zacopride selectively labels with high affinity 5-ht3 recognition sites in human amygdala and hippocampus and, if these binding domains represent 5-ht3 receptors, may provide the opportunity for 5-ht3 receptor antagonists to modify 5-ht function in the human brain. |
1989-12-21 |
2023-08-11 |
human |
| L A Hilakivi, M Ota, R G Liste. Effect of isolation on brain monoamines and the behavior of mice in tests of exploration, locomotion, anxiety and behavioral 'despair'. Pharmacology, biochemistry, and behavior. vol 33. issue 2. 1989-12-19. PMID:2479036. |
monoamine assays failed to show significant changes in the noradrenaline, dopamine, hva, 5-ht or 5-hiaa contents in the amygdala, hypothalamus, hippocampus or brain stem. |
1989-12-19 |
2023-08-11 |
mouse |
| Q Pei, T Zetterström, M Fillen. Both systemic and local administration of benzodiazepine agonists inhibit the in vivo release of 5-HT from ventral hippocampus. Neuropharmacology. vol 28. issue 10. 1989-12-13. PMID:2478921. |
both systemic and local administration of benzodiazepine agonists inhibit the in vivo release of 5-ht from ventral hippocampus. |
1989-12-13 |
2023-08-11 |
rat |
| Q Pei, T Zetterström, M Fillen. Both systemic and local administration of benzodiazepine agonists inhibit the in vivo release of 5-HT from ventral hippocampus. Neuropharmacology. vol 28. issue 10. 1989-12-13. PMID:2478921. |
the effects of benzodiazepine- and gabaa-receptor agonists and antagonists on the release and metabolism of 5-ht were measured in the ventral hippocampus of freely moving rats using microdialysis. |
1989-12-13 |
2023-08-11 |
rat |
| Q Pei, T Zetterström, M Fillen. Both systemic and local administration of benzodiazepine agonists inhibit the in vivo release of 5-HT from ventral hippocampus. Neuropharmacology. vol 28. issue 10. 1989-12-13. PMID:2478921. |
local perfusion of flurazepam through the dialysis probe also decreased the release of 5-ht in the ventral hippocampus, an effect which was completely blocked by the benzodiazepine antagonist, ro15-1788 (flumazenil). |
1989-12-13 |
2023-08-11 |
rat |
| Q Pei, T Zetterström, M Fillen. Both systemic and local administration of benzodiazepine agonists inhibit the in vivo release of 5-HT from ventral hippocampus. Neuropharmacology. vol 28. issue 10. 1989-12-13. PMID:2478921. |
none of these drugs caused significant changes in the levels of the metabolite of 5-ht, 5-hydroxyindoleacetic acid (5-hiaa) in the ventral hippocampus. |
1989-12-13 |
2023-08-11 |
rat |
| Q Pei, T Zetterström, M Fillen. Both systemic and local administration of benzodiazepine agonists inhibit the in vivo release of 5-HT from ventral hippocampus. Neuropharmacology. vol 28. issue 10. 1989-12-13. PMID:2478921. |
these results suggest that the inhibitory effect of flurazepam on the release of 5-ht is mediated by benzodiazepine/gabaa receptors in the hippocampus and that gaba exerts a tonic inhibitory effect on the release of 5-ht in the region of the brain. |
1989-12-13 |
2023-08-11 |
rat |
| S C Cheetham, Y Yamaguchi, R W Horto. [3H]5-hydroxytryptamine binding sites in postmortem human brain. Neuropharmacology. vol 28. issue 10. 1989-12-13. PMID:2530468. |
binding sites for [3h]5-hydroxytryptamine (5-ht) in postmortem human frontal cortex, hippocampus and amygdala were studied by displacement with 5-ht selective drugs. |
1989-12-13 |
2023-08-11 |
human |
| F Chaouloff, D Laude, J L Elghoz. PHysical exercise: evidence for differential consequences of tryptophan on 5-HT synthesis and metabolism in central serotonergic cell bodies and terminals. Journal of neural transmission. vol 78. issue 2. 1989-12-07. PMID:2478662. |
the aim of the present study was to investigate the effects of physical exercise (running) on serotonin (5-hydroxytryptamine, 5-ht) synthesis and metabolism in midbrain on the one hand, and in striatum and hippocampus on the other hand. |
1989-12-07 |
2023-08-11 |
rat |
| F Chaouloff, D Laude, J L Elghoz. PHysical exercise: evidence for differential consequences of tryptophan on 5-HT synthesis and metabolism in central serotonergic cell bodies and terminals. Journal of neural transmission. vol 78. issue 2. 1989-12-07. PMID:2478662. |
although running triggered a 30% increase in trp levels in the three brain regions examined, inhibition of 5-ht synthesis by nsd 1015 was found to promote increased (midbrain), unchanged (striatum) or decreased (hippocampus) 5-htp accumulation in the running situation, respectively compared to that measured in the resting situation. |
1989-12-07 |
2023-08-11 |
rat |
| F Chaouloff, D Laude, J L Elghoz. PHysical exercise: evidence for differential consequences of tryptophan on 5-HT synthesis and metabolism in central serotonergic cell bodies and terminals. Journal of neural transmission. vol 78. issue 2. 1989-12-07. PMID:2478662. |
inasmuch as running-induced elevation in trp was not associated with an increased 5-htp accumulation in the striatum and the hippocampus, the consequences of running on regional trp, 5-ht and 5-hiaa levels were analyzed in saline- and trp-injected rats. |
1989-12-07 |
2023-08-11 |
rat |
| M Martire, G Pistritto, P Prezios. Different regulation of serotonin receptors following adrenal hormone imbalance in the rat hippocampus and hypothalamus. Journal of neural transmission. vol 78. issue 2. 1989-12-07. PMID:2553860. |
different regulation of serotonin receptors following adrenal hormone imbalance in the rat hippocampus and hypothalamus. |
1989-12-07 |
2023-08-11 |
rat |