| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A M Di Giulio, B Tenconi, R La Croix, P Mantegazza, M P Abbracchio, F Cattabeni, A Gori. Denervation and hyperinnervation in the nervous system of diabetic animals. II. Monoaminergic and peptidergic alterations in the diabetic encephalopathy. Journal of neuroscience research. vol 24. issue 3. 1990-01-22. PMID:2480454. |
in the hippocampus, there is a reduction of serotonin content. |
1990-01-22 |
2023-08-11 |
rat |
| J Buelke-Sam, S F Ali, G L Kimmel, W Slikker, G D Newport, J R Harmo. Postnatal function following prenatal reserpine exposure in rats: neurobehavioral toxicity. Neurotoxicology and teratology. vol 11. issue 5. 1990-01-17. PMID:2593990. |
however, hippocampal 5-ht and 5-ht receptor binding were significantly reduced only in females. |
1990-01-17 |
2023-08-11 |
rat |
| M Johnson, G R Hanson, J W Gib. Characterization of acute N-ethyl-3,4-methylenedioxyamphetamine (MDE) action on the central serotonergic system. Biochemical pharmacology. vol 38. issue 23. 1990-01-16. PMID:2480796. |
within 1 hr after administration of mde (10 mg/kg), the concentration of 5-hydroxytryptamine (5-ht) and the activity of tryptophan hydroxylase (tph) had declined significantly in the hippocampus but returned to control within 12 hr. |
1990-01-16 |
2023-08-11 |
Not clear |
| F Bolanos, G Fillio. Minaprine antagonises the serotonergic inhibitory effect of trifluoromethylphenylpiperazine (TFMPP) on acetylcholine release. European journal of pharmacology. vol 168. issue 1. 1990-01-11. PMID:2583235. |
the serotonin agonist, m-trifluoromethylphenylpiperazine (tfmpp), inhibited the k+-evoked release of [3h]acetylcholine ([3h]ach) from rat hippocampal synaptosomes. |
1990-01-11 |
2023-08-11 |
rat |
| S C Cheetham, M R Crompton, C Czudek, R W Horton, C L Katona, G P Reynold. Serotonin concentrations and turnover in brains of depressed suicides. Brain research. vol 502. issue 2. 1990-01-08. PMID:2479456. |
5-ht, 5-hiaa and 5-ht turnover did not differ significantly between the total, drug-free and antidepressant-treated suicides and controls in frontal and temporal cortex, caudate and hippocampus. |
1990-01-08 |
2023-08-11 |
human |
| M Segal, E C Azmitia, P M Whitaker-Azmiti. Physiological effects of selective 5-HT1a and 5-HT1b ligands in rat hippocampus: comparison to 5-HT. Brain research. vol 502. issue 1. 1990-01-04. PMID:2531014. |
physiological effects of selective 5-ht1a and 5-ht1b ligands in rat hippocampus: comparison to 5-ht. |
1990-01-04 |
2023-08-11 |
rat |
| M Segal, E C Azmitia, P M Whitaker-Azmiti. Physiological effects of selective 5-HT1a and 5-HT1b ligands in rat hippocampus: comparison to 5-HT. Brain research. vol 502. issue 1. 1990-01-04. PMID:2531014. |
the responses of ca1 neurons to topical application of serotonin (5-ht) and selective 5-ht1a and 5-ht1b agonists were examined with intracellular recording in the hippocampal slice. |
1990-01-04 |
2023-08-11 |
rat |
| M Segal, E C Azmitia, P M Whitaker-Azmiti. Physiological effects of selective 5-HT1a and 5-HT1b ligands in rat hippocampus: comparison to 5-HT. Brain research. vol 502. issue 1. 1990-01-04. PMID:2531014. |
it is suggested that the physiological response to 5-ht in the rat hippocampus is mediated by a 5-ht1a receptor. |
1990-01-04 |
2023-08-11 |
rat |
| M Segal, E C Azmitia, P M Whitaker-Azmiti. Physiological effects of selective 5-HT1a and 5-HT1b ligands in rat hippocampus: comparison to 5-HT. Brain research. vol 502. issue 1. 1990-01-04. PMID:2531014. |
the currently available 5-ht1a ligands show a low agonist potential and a high antagonist action towards the responses of hippocampal neurons to 5-ht. |
1990-01-04 |
2023-08-11 |
rat |
| M R Pranzatelli, Y Y Huang, A M Dollison, M Stanle. Brainstem serotonergic hyperinnervation modifies behavioral supersensitivity to 5-hydroxytryptophan in the rat. Brain research. Developmental brain research. vol 50. issue 1. 1990-01-04. PMID:2582610. |
after 14 weeks, 5-ht was selectively depleted (-43 to -92%) in hippocampus, spinal cord, and frontal cortex, and differences between i.c. |
1990-01-04 |
2023-08-11 |
rat |
| J L Muir, H P Pfiste. Psychological stress and oxytocin treatment during pregnancy affect central norepinephrine, dopamine and serotonin in lactating rats. The International journal of neuroscience. vol 48. issue 3-4. 1990-01-04. PMID:2583934. |
the aim of these experiments was to investigate the effects of psychological stress and oxytocin treatment on levels of norepinephrine, dopamine and serotonin in the hypothalamus, hippocampus, striatum, midbrain and brainstem of lactating females. |
1990-01-04 |
2023-08-11 |
rat |
| J L Muir, H P Pfiste. Psychological stress and oxytocin treatment during pregnancy affect central norepinephrine, dopamine and serotonin in lactating rats. The International journal of neuroscience. vol 48. issue 3-4. 1990-01-04. PMID:2583934. |
furthermore, a marked reduction in serotonin levels in the hypothalamus, hippocampus, midbrain and brainstem was observed as a result of oxytocin treatment on both day 6 and day 21 postpartum. |
1990-01-04 |
2023-08-11 |
rat |
| S G Beck, W P Clarke, J Goldfar. Chronic estrogen effects on 5-hydroxytryptamine-mediated responses in hippocampal pyramidal cells of female rats. Neuroscience letters. vol 106. issue 1-2. 1990-01-04. PMID:2586823. |
intracellular recording techniques were used to assess the effect of chronic estrogen treatment of ovariectomized (ovx) rats on ca1 pyramidal cell properties and serotonin (5-ht)-mediated responses in the dorsal hippocampus. |
1990-01-04 |
2023-08-11 |
rat |
| A Mørk, A Geisle. Effects of lithium ex vivo on the GTP-mediated inhibition of calcium-stimulated adenylate cyclase activity in rat brain. European journal of pharmacology. vol 168. issue 3. 1990-01-03. PMID:2583240. |
serotonin (5-ht) dose dependently reduced ca2+-stimulated adenylate cyclase activity in the hippocampus, and chronic lithium administration reduced the ability of 1 microm 5-ht to inhibit ca2+-stimulated enzyme activity. |
1990-01-03 |
2023-08-11 |
rat |
| A Mørk, A Geisle. Effects of lithium ex vivo on the GTP-mediated inhibition of calcium-stimulated adenylate cyclase activity in rat brain. European journal of pharmacology. vol 168. issue 3. 1990-01-03. PMID:2583240. |
furthermore, long-term administration of lithium could reduce the inhibitory effect of 5-ht on adenylate cyclase in the hippocampus, by influencing the inhibitory gtp-binding protein. |
1990-01-03 |
2023-08-11 |
rat |
| T A Reader, K M Dewar, L Grondi. Distribution of monoamines and metabolites in rabbit neostriatum, hippocampus and cortex. Brain research bulletin. vol 23. issue 3. 1990-01-03. PMID:2819481. |
the monoamines noradrenaline (na), dopamine (da), adrenaline (ad) and 5-hydroxytryptamine (5-ht) were assayed in the putamen (put), the lateral (lcau) and medial (mcau) portions of the caudate, the dorsal (dhip) and ventral (vhip) hippocampus, as well as in four cortical areas, i.e., anterior cingulate (cin), entorhinal-piriform (enpi), sensorimotor (ssc; somatosensory) and primary visual (vis). |
1990-01-03 |
2023-08-11 |
rabbit |
| A A Li, G J Marek, G Vosmer, L S Seide. Long-term central 5-HT depletions resulting from repeated administration of MDMA enhances the effects of single administration of MDMA on schedule-controlled behavior of rats. Pharmacology, biochemistry, and behavior. vol 33. issue 3. 1989-12-29. PMID:2573905. |
repeated administration of mdma resulted in long-term depletion of serotonin levels by 30-50% in the amygdala, neostriatum, hippocampus and the frontal cortex. |
1989-12-29 |
2023-08-11 |
rat |
| S Wieland, D Goodale, I Luck. Behavioral effects of 8-OH-DPAT: studies using the Microtaxic ventricular injector. Journal of neuroscience methods. vol 30. issue 2. 1989-12-28. PMID:2531256. |
injection of the 5-ht neurotoxin produced a 79% depletion of 5-ht in the cortex and an 86% depletion of 5-ht in the hippocampus. |
1989-12-28 |
2023-08-11 |
rat |
| M C Buhot, P Rage, L Seg. Changes in exploratory behaviour of hamsters following treatment with 8-hydroxy-2-(di-n-propylamino)tetralin. Behavioural brain research. vol 35. issue 2. 1989-12-22. PMID:2530993. |
8-oh-dpat is assumed to act on 5-ht somatodendritic autoreceptors, lowering 5-ht utilization in the hippocampus, which is the main structure implicated in spatial memory. |
1989-12-22 |
2023-08-11 |
human |
| K T Finnegan, L E DeLanney, I Irwin, G A Ricaurte, J W Langsto. The amine-depleting effects of 5,7-dihydroxytryptamine (5,7-DHT) in C57BL/6 mice do not increase with age. Brain research. vol 496. issue 1-2. 1989-12-21. PMID:2804634. |
norepinephrine and serotonin in the hippocampus were assayed 1 week after the intracerebroventricular (i.c.v.) |
1989-12-21 |
2023-08-11 |
mouse |