| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Yoshioka, M Matsumoto, H Togashi, C B Smith, H Sait. Opioid receptor regulation of 5-hydroxytryptamine release from the rat hippocampus measured by in vivo microdialysis. Brain research. vol 613. issue 1. 1993-09-15. PMID:8394180. |
the hippocampus was perfused with ringer's solution (2 microliters/min), and extracellular levels of 5-ht and its major metabolite, 5-hydroxyindoleacetic acid (5-hiaa) were estimated by assaying their concentration in the dialysate by hplc-ecd. |
1993-09-15 |
2023-08-12 |
rat |
| M Yoshioka, M Matsumoto, H Togashi, C B Smith, H Sait. Opioid receptor regulation of 5-hydroxytryptamine release from the rat hippocampus measured by in vivo microdialysis. Brain research. vol 613. issue 1. 1993-09-15. PMID:8394180. |
these findings indicate that mu-opioid receptors modulate the physiological release of 5-ht from serotonergic neurons in the rat hippocampus. |
1993-09-15 |
2023-08-12 |
rat |
| A N Talalaenko, N A Khari. [The mechanisms of the anxiolytic action of 1-(2-pyrimidinyl)-piperazine derivatives, serotonin agonists]. Eksperimental'naia i klinicheskaia farmakologiia. vol 56. issue 2. 1993-09-14. PMID:8102289. |
5-ht locally injected into the nucleus raphe and hippocampus revealed a role of serotoninergic mechanisms of these brain formations in the studied anxiety conditions of different aversive genesis. |
1993-09-14 |
2023-08-12 |
rat |
| A N Talalaenko, N A Khari. [The mechanisms of the anxiolytic action of 1-(2-pyrimidinyl)-piperazine derivatives, serotonin agonists]. Eksperimental'naia i klinicheskaia farmakologiia. vol 56. issue 2. 1993-09-14. PMID:8102289. |
it is concluded that anxiolytic effect dissociation revealed in different anxiety tests, are stipulated by serotonin and its agonists due to nucleus raphe and hippocampus chemical stimulation my suggest their different neurochemical contribution and nonserotoninergic component involved in the mechanism of 1-(2-pyrimidinyl)-piperazine derivative anxiolytic action. |
1993-09-14 |
2023-08-12 |
rat |
| M E Dell'Anna, J Luthman, E Lindqvist, L Olso. Development of monoamine systems after neonatal anoxia in rats. Brain research bulletin. vol 32. issue 2. 1993-09-14. PMID:8348340. |
at p21, increased hippocampal na and striatal homovanillic acid (hva) were found, while striatal 5-ht decreased and 5-hiaa increased in striatum and hippocampus. |
1993-09-14 |
2023-08-12 |
rat |
| M E Dell'Anna, J Luthman, E Lindqvist, L Olso. Development of monoamine systems after neonatal anoxia in rats. Brain research bulletin. vol 32. issue 2. 1993-09-14. PMID:8348340. |
no effects were seen on 5-ht, tyrosine hydroxylase, or darpp-32 immunostaining in cortex, hippocampus, and striatum. |
1993-09-14 |
2023-08-12 |
rat |
| M C Cassone, A Lombard, V Rossetti, R Urciuoli, P M Rolf. Effect of in vivo He-Ne laser irradiation on biogenic amine levels in rat brain. Journal of photochemistry and photobiology. B, Biology. vol 18. issue 2-3. 1993-09-14. PMID:8350195. |
the results obtained on groups of four to eight rats assayed individually showed that irradiation caused a strong increase in 5-ht in striatum and hippocampus, a small but significant decrease in na in cortex, and da levels were not significantly affected. |
1993-09-14 |
2023-08-12 |
rat |
| M C Cassone, A Lombard, V Rossetti, R Urciuoli, P M Rolf. Effect of in vivo He-Ne laser irradiation on biogenic amine levels in rat brain. Journal of photochemistry and photobiology. B, Biology. vol 18. issue 2-3. 1993-09-14. PMID:8350195. |
restraint stress per se led to a considerable decrease in 5-ht and da in striatum and hippocampus, but did not significantly alter the na levels. |
1993-09-14 |
2023-08-12 |
rat |
| B B Höök, A M Johansson, S Hjorth, S Sundell, U Hacksel. Synthesis of (+)-(R)- and (-)-(S)-5-hydroxy-2-methyl-2-dipropylaminotetralin: effects on rat hippocampal output of 5-HT, 5-HIAA, and DOPAC as determined by in vivo microdialysis. Chirality. vol 5. issue 3. 1993-09-02. PMID:7687852. |
synthesis of (+)-(r)- and (-)-(s)-5-hydroxy-2-methyl-2-dipropylaminotetralin: effects on rat hippocampal output of 5-ht, 5-hiaa, and dopac as determined by in vivo microdialysis. |
1993-09-02 |
2023-08-12 |
rat |
| B B Höök, A M Johansson, S Hjorth, S Sundell, U Hacksel. Synthesis of (+)-(R)- and (-)-(S)-5-hydroxy-2-methyl-2-dipropylaminotetralin: effects on rat hippocampal output of 5-HT, 5-HIAA, and DOPAC as determined by in vivo microdialysis. Chirality. vol 5. issue 3. 1993-09-02. PMID:7687852. |
the enantiomers of 2 were tested for hippocampal output of 5-hydroxytryptamine, 5-hydroxyindoleacetic acid, and dihydroxyphenylacetic acid in rats by use of in vivo microdialysis. |
1993-09-02 |
2023-08-12 |
rat |
| G Richter-Levin, V Greenberger, M Sega. Regional specificity of raphe graft-induced recovery of behavioral functions impaired by combined serotonergic/cholinergic lesions. Experimental neurology. vol 121. issue 2. 1993-08-31. PMID:8339776. |
serotonin depletion or partial cholinergic lesion of the hippocampus (by injection of colchicine into the septum) did not affect the ability of rats to perform the task, but the combined treatment did. |
1993-08-31 |
2023-08-12 |
rat |
| b' D Muck-Seler, D Perici\\xc4\\x8. Possible antidepressant dihydroergosine preferentially binds to 5-HT1B receptor sites in the rat hippocampus. Journal of neural transmission. General section. vol 92. issue 1. 1993-08-17. PMID:8329168.' |
dihydroergosine displaced the binding of [3h]5-ht to the whole population of hippocampal 5-ht1 receptors with high affinity (ki = 4.8 nm). |
1993-08-17 |
2023-08-12 |
rat |
| A R Chubakov, V G Tsyganova, E F Sarkisov. The stimulating influence of the raphé nuclei on the morphofunctional development of the hippocampus during their combined cultivation. Neuroscience and behavioral physiology. vol 23. issue 3. 1993-08-17. PMID:8332246. |
these data are in agreement with previously established effects of exogenous serotonin, and attest to an important role of the serotoninergic influences of the raphé nuclei in the morphofunctional development of the hippocampus. |
1993-08-17 |
2023-08-12 |
rat |
| J A Lawrence, H J Olverman, K Shirakawa, J S Kelly, S P Butche. Binding of 5-HT1A receptor and 5-HT transporter ligands in rat cortex and hippocampus following cholinergic and serotonergic lesions. Brain research. vol 612. issue 1-2. 1993-08-13. PMID:7687192. |
binding of 5-ht1a receptor and 5-ht transporter ligands in rat cortex and hippocampus following cholinergic and serotonergic lesions. |
1993-08-13 |
2023-08-12 |
rat |
| J A Lawrence, H J Olverman, K Shirakawa, J S Kelly, S P Butche. Binding of 5-HT1A receptor and 5-HT transporter ligands in rat cortex and hippocampus following cholinergic and serotonergic lesions. Brain research. vol 612. issue 1-2. 1993-08-13. PMID:7687192. |
the cellular localisation of 5-ht1a receptor and 5-ht transporter binding sites in the rat cortex and hippocampus has been examined. |
1993-08-13 |
2023-08-12 |
rat |
| J A Lawrence, H J Olverman, K Shirakawa, J S Kelly, S P Butche. Binding of 5-HT1A receptor and 5-HT transporter ligands in rat cortex and hippocampus following cholinergic and serotonergic lesions. Brain research. vol 612. issue 1-2. 1993-08-13. PMID:7687192. |
the binding of the 5-ht transporter ligand, [3h]citalopram was unaffected by the cholinergic lesion whereas binding was reduced in both the hippocampus and cortex following serotonergic lesions. |
1993-08-13 |
2023-08-12 |
rat |
| K M Dewar, L Grondin, E K Nénonéné, M Ohayon, T A Reade. [3H]paroxetine binding and serotonin content of rat brain: absence of changes following antidepressant treatments. European journal of pharmacology. vol 235. issue 1. 1993-07-29. PMID:8519275. |
tissue concentrations of serotonin and of its metabolite 5-hydroxyindole-3-acetic acid were also determined by high-performance liquid chromatography in cingulate cerebral cortex, rostral neostriatum, hippocampus and midbrain raphe nucleus region. |
1993-07-29 |
2023-08-12 |
rat |
| b' A N Talalaenko, G K Krivobok, Iu V Stakhovski\\xc4\\xa. [The role of monoamin- and acidergic mechanisms of the hippocampus in anxiety states of different origins and their participation in the antiaversive effects of anxiolytics]. Fiziologicheskii zhurnal imeni I.M. Sechenova. vol 79. issue 1. 1993-07-28. PMID:8100168.' |
the experiments on rats with tests of avoiding "lighting square" and "threatening situation" and with the chemical stimulation of dorsal and ventral hippocampus with dopamine, 5-ht, gaba and glutamine acid, showed different functional significance of these monoamines and acidergic transmitters agents in the states of anxiety of heteromodal aversive genesis. |
1993-07-28 |
2023-08-12 |
rat |
| b' A N Talalaenko, G K Krivobok, Iu V Stakhovski\\xc4\\xa. [The role of monoamin- and acidergic mechanisms of the hippocampus in anxiety states of different origins and their participation in the antiaversive effects of anxiolytics]. Fiziologicheskii zhurnal imeni I.M. Sechenova. vol 79. issue 1. 1993-07-28. PMID:8100168.' |
it seems that the variations in the action spectrum of anxiolytics under study are due to unequal degree of 5-ht and gaba-ergic transmitter mechanisms of dorsal and ventral hippocampus. |
1993-07-28 |
2023-08-12 |
rat |
| J N Joyce, A Shane, N Lexow, A Winokur, M F Casanova, J E Kleinma. Serotonin uptake sites and serotonin receptors are altered in the limbic system of schizophrenics. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 8. issue 4. 1993-07-20. PMID:8512620. |
in the parahippocampal gyrus and hippocampus, the distribution of 5-ht uptake sites was complementary to the distribution of 5-ht1a and 5-ht2 receptors. |
1993-07-20 |
2023-08-12 |
Not clear |