| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Cui, T F Lee, L C Wan. Thermoregulatory responses following injection of 5-hydroxytryptamine into the septohippocampal complex in rats. Pharmacology, biochemistry, and behavior. vol 45. issue 4. 1993-10-26. PMID:8415834. |
the present study investigated the change in thermoregulatory responses following microinjection of 5-hydroxytryptamine (5-ht) into the lateral septum and the hippocampus of unanesthetized, unrestrained rats. |
1993-10-26 |
2023-08-12 |
rat |
| Y Cui, T F Lee, L C Wan. Thermoregulatory responses following injection of 5-hydroxytryptamine into the septohippocampal complex in rats. Pharmacology, biochemistry, and behavior. vol 45. issue 4. 1993-10-26. PMID:8415834. |
in contrast to observed changes following intraseptal injection, no significant change in either tb or hp was observed after microinjection of the same doses of 5-ht into the hippocampal areas, indicating that the hypothermic response to intraseptal injection of 5-ht is site specific. |
1993-10-26 |
2023-08-12 |
rat |
| J A Harvey, S E McMaster, A G Roman. Methylenedioxyamphetamine: neurotoxic effects on serotonergic projections to brainstem nuclei in the rat. Brain research. vol 619. issue 1-2. 1993-10-20. PMID:7690669. |
in agreement with previous reports, mda produced a pronounced loss of 5-ht immunoreactivity in the forebrain, most notably in neocortex and hippocampus. |
1993-10-20 |
2023-08-12 |
rat |
| J S Sprouse, D R McCarty, M W Dudle. Apparent regional differences in 5-HT1A binding may reflect [3H]8-OH-DPAT labeling of serotonin uptake sites. Brain research. vol 617. issue 1. 1993-10-15. PMID:8374738. |
the binding of [3h]8-oh-dpat and [3h]paroxetine to 5-ht1a and 5-ht uptake sites (respectively) was examined in membranes prepared from bovine dorsal raphe and hippocampus. |
1993-10-15 |
2023-08-12 |
cattle |
| T Ohmori, T Koyama, A Muraki, I Yamashit. Competitive and noncompetitive N-methyl-D-aspartate antagonists protect dopaminergic and serotonergic neurotoxicity produced by methamphetamine in various brain regions. Journal of neural transmission. General section. vol 92. issue 2-3. 1993-10-12. PMID:7690233. |
four injections of ma (7.5 mg/kg, s.c., at 2 h intervals) caused significant decrements (40-60% of control values) in levels of dopamine (da) and its metabolites in the rat striatum and levels of serotonin (5-ht) and its metabolite in the medial prefrontal cortex, nucleus accumbens, striatum, anterior hypothalamus, amygdala and hippocampus. |
1993-10-12 |
2023-08-12 |
rat |
| Y Watanabe, R R Sakai, B S McEwen, S Mendelso. Stress and antidepressant effects on hippocampal and cortical 5-HT1A and 5-HT2 receptors and transport sites for serotonin. Brain research. vol 615. issue 1. 1993-10-05. PMID:8364729. |
stress and antidepressant effects on hippocampal and cortical 5-ht1a and 5-ht2 receptors and transport sites for serotonin. |
1993-10-05 |
2023-08-12 |
rat |
| Y Watanabe, R R Sakai, B S McEwen, S Mendelso. Stress and antidepressant effects on hippocampal and cortical 5-HT1A and 5-HT2 receptors and transport sites for serotonin. Brain research. vol 615. issue 1. 1993-10-05. PMID:8364729. |
the interactions between 14 days of repeated restraint stress and daily administration of imipramine or tianeptine (2 h before the beginning of stress) were investigated in rats to assess responses of 5-ht2 and 5-ht1a receptors and serotonin transporter sites labelled by [3h]paroxetine in the cerebral cortex and hippocampus, two brain regions in which adrenal steroid effects on serotonin receptor-binding have been reported. |
1993-10-05 |
2023-08-12 |
rat |
| Y Watanabe, R R Sakai, B S McEwen, S Mendelso. Stress and antidepressant effects on hippocampal and cortical 5-HT1A and 5-HT2 receptors and transport sites for serotonin. Brain research. vol 615. issue 1. 1993-10-05. PMID:8364729. |
[3h]paroxetine-binding to serotonin transporter sites was decreased by tianeptine treatment as well as by imipramine in both hippocampus and cerebral cortex, with some overlap of the fields that were significantly affected, whereas there were no effects of stress per se and no evidence of a stress x drug interaction. |
1993-10-05 |
2023-08-12 |
rat |
| V N Luine, R L Spencer, B S McEwe. Effects of chronic corticosterone ingestion on spatial memory performance and hippocampal serotonergic function. Brain research. vol 616. issue 1-2. 1993-09-30. PMID:7689414. |
corticosterone treatment was associated with a long lasting (5 weeks post treatment) increase in 5-ht levels (44%) in the dentate gyrus of the hippocampus and decrease in 5-ht (50%) and ne (36%) levels in the frontal cortex. |
1993-09-30 |
2023-08-12 |
human |
| A N Talalaenk. [The neurochemical profile of the dorsal hippocampus and the antiaversive effects of anxiolytics in different models of anxiety in rats]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 43. issue 3. 1993-09-30. PMID:8103252. |
chemical stimulation of the dorsal hippocampus by serotonin and gaba decreases anxiety in a test of avoidance of precarious situation but not of illuminated platform. |
1993-09-30 |
2023-08-12 |
rat |
| T Sharp, R McQuade, J R Fozard, D Hoye. The novel 5-HT1A receptor antagonist, SDZ 216-525, decreases 5-HT release in rat hippocampus in vivo. British journal of pharmacology. vol 109. issue 3. 1993-09-28. PMID:8102935. |
the novel 5-ht1a receptor antagonist, sdz 216-525, decreases 5-ht release in rat hippocampus in vivo. |
1993-09-28 |
2023-08-12 |
rat |
| T Sharp, R McQuade, J R Fozard, D Hoye. The novel 5-HT1A receptor antagonist, SDZ 216-525, decreases 5-HT release in rat hippocampus in vivo. British journal of pharmacology. vol 109. issue 3. 1993-09-28. PMID:8102935. |
the experiments involved measurement of drug effects on extracellular 5-ht in the ventral hippocampus of the chloral hydrate anaesthetized rat by use of microdialysis. |
1993-09-28 |
2023-08-12 |
rat |
| T Sharp, R McQuade, J R Fozard, D Hoye. The novel 5-HT1A receptor antagonist, SDZ 216-525, decreases 5-HT release in rat hippocampus in vivo. British journal of pharmacology. vol 109. issue 3. 1993-09-28. PMID:8102935. |
although in several experimental models sdz 216-525 has high affinity, selectivity and lacks intrinsic activity at the 5-ht1a receptor, our experiments show that the drug decreases extracellular 5-ht in ventral hippocampus of the chloral hydrate anaesthetized rat via a pindolol-sensitive mechanism. |
1993-09-28 |
2023-08-12 |
rat |
| Y Shirayama, T Nishikawa, A Umino, K Takahash. p-chlorophenylalanine-reversible reduction of sigma binding sites by chronic imipramine treatment in rat brain. European journal of pharmacology. vol 237. issue 1. 1993-09-28. PMID:8359206. |
finally, depletion of brain serotonin by means of repeated administration of p-chlorophenylalanine, which produces inhibition of the amine synthesis, blocked the ability of repeated imipramine treatment to reduce the maximal number of [3h]dtg binding sites in the striatum and hippocampus. |
1993-09-28 |
2023-08-12 |
rat |
| L Lima, M Salazar, E Trej. Modulation of 5HT1A receptors in the hippocampus and the raphe area of rats treated with clonazepam. Progress in neuro-psychopharmacology & biological psychiatry. vol 17. issue 4. 1993-09-24. PMID:7689737. |
the acute and subchronic administration of clonazepam reduced serotonin (5ht) turnover rate in the hippocampus of the rat, as determined by the ratio of the monoamine and its metabolite, 5-hydroxyindoleacetic acid. |
1993-09-24 |
2023-08-12 |
rat |
| L Lima, M Salazar, E Trej. Modulation of 5HT1A receptors in the hippocampus and the raphe area of rats treated with clonazepam. Progress in neuro-psychopharmacology & biological psychiatry. vol 17. issue 4. 1993-09-24. PMID:7689737. |
the modulation of 5ht binding sites and 5ht1a receptors by the administration of clonazepam for various periods of time were studied in the hippocampus and the raphe area by experiments with radioligands. |
1993-09-24 |
2023-08-12 |
rat |
| L Lima, M Salazar, E Trej. Modulation of 5HT1A receptors in the hippocampus and the raphe area of rats treated with clonazepam. Progress in neuro-psychopharmacology & biological psychiatry. vol 17. issue 4. 1993-09-24. PMID:7689737. |
the density of [3h]5ht recognition sites increased in the hippocampus of clonazepam-treated rats in a dose- and time-dependent manner. |
1993-09-24 |
2023-08-12 |
rat |
| R Zaczek, W J Tinker, S W Ta. Unique properties of norepinephrine release from terminals arising from the locus coeruleus: high potassium sensitivity and lack of linopirdine (DuP 996) enhancement. Neuroscience letters. vol 155. issue 1. 1993-09-24. PMID:8361656. |
cerebral cortical and hippocampal [3h]ne release had steeper k+ dose-response curves than those observed for apparent hippocampal [3h]ach, striatal [3h]da and striatal [3h]5-ht release. |
1993-09-24 |
2023-08-12 |
rat |
| M Yoshioka, M Matsumoto, H Togashi, C B Smith, H Sait. Opioid receptor regulation of 5-hydroxytryptamine release from the rat hippocampus measured by in vivo microdialysis. Brain research. vol 613. issue 1. 1993-09-15. PMID:8394180. |
opioid receptor regulation of 5-hydroxytryptamine release from the rat hippocampus measured by in vivo microdialysis. |
1993-09-15 |
2023-08-12 |
rat |
| M Yoshioka, M Matsumoto, H Togashi, C B Smith, H Sait. Opioid receptor regulation of 5-hydroxytryptamine release from the rat hippocampus measured by in vivo microdialysis. Brain research. vol 613. issue 1. 1993-09-15. PMID:8394180. |
the modulation of serotonin (5-ht) release by opioid receptors in the hippocampus of the awake, unrestrained rat was evaluated by use of in vivo microdialysis. |
1993-09-15 |
2023-08-12 |
rat |