| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J N Joyce, A Shane, N Lexow, A Winokur, M F Casanova, J E Kleinma. Serotonin uptake sites and serotonin receptors are altered in the limbic system of schizophrenics. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 8. issue 4. 1993-07-20. PMID:8512620. |
there was a marked reduction in 5-ht uptake sites in the external and middle laminae of the anterior cingulate, frontal cortex, and posterior cingulate, and no changes were observed in the motor cortex, temporal cortex, or hippocampus. |
1993-07-20 |
2023-08-12 |
Not clear |
| S F Ali, G D Newport, A C Scallet, Z Binienda, S A Ferguson, J R Bailey, M G Paule, W Slikke. Oral administration of 3,4-methylenedioxymethamphetamine (MDMA) produces selective serotonergic depletion in the nonhuman primate. Neurotoxicology and teratology. vol 15. issue 2. 1993-07-15. PMID:7685472. |
the lower doses of mdma (1.25 and 2.5 mg/kg) did not significantly alter 5-ht or 5-hiaa concentrations in any brain region except hippocampus in which 5-ht concentrations were decreased after 2.5 mg/kg. |
1993-07-15 |
2023-08-12 |
human |
| H J Cassaday, S N Mitchell, J H Williams, J A Gra. 5,7-Dihydroxytryptamine lesions in the fornix-fimbria attenuate latent inhibition. Behavioral and neural biology. vol 59. issue 3. 1993-06-30. PMID:8503825. |
the present study investigated the role of hippocampal 5ht terminals in latent inhibition using a conditioned suppression procedure with male sprague-dawley rats. |
1993-06-30 |
2023-08-12 |
rat |
| E Edwards, W Kornrich, P van Houtten, F A Hen. In vitro neurotransmitter release in an animal model of depression. Neurochemistry international. vol 21. issue 1. 1993-06-24. PMID:1303140. |
the major finding concerned a significant increase in endogenous and k(+)-stimulated serotonin (5-ht) release in the hippocampal slices of lh rats. |
1993-06-24 |
2023-08-11 |
rat |
| N Weiner, H W Clement, D Gemsa, W Weseman. Circadian and seasonal rhythms of 5-HT receptor subtypes, membrane anisotropy and 5-HT release in hippocampus and cortex of the rat. Neurochemistry international. vol 21. issue 1. 1993-06-24. PMID:1363861. |
circadian and seasonal rhythms of 5-ht receptor subtypes, membrane anisotropy and 5-ht release in hippocampus and cortex of the rat. |
1993-06-24 |
2023-08-11 |
rat |
| N Weiner, H W Clement, D Gemsa, W Weseman. Circadian and seasonal rhythms of 5-HT receptor subtypes, membrane anisotropy and 5-HT release in hippocampus and cortex of the rat. Neurochemistry international. vol 21. issue 1. 1993-06-24. PMID:1363861. |
specific serotonin binding (5-ht1, 5-ht1a, and 5-ht2 subtypes) and membrane anisotropy were measured at 2 h intervals over a 24 h period in the hippocampus and cortex of wistar wu rats, housed under a 12 h light-dark cycle, with lights on at 07.00. |
1993-06-24 |
2023-08-11 |
rat |
| S Hjorth, T Shar. In vivo microdialysis evidence for central serotonin1A and serotonin1B autoreceptor blocking properties of the beta adrenoceptor antagonist (-)penbutolol. The Journal of pharmacology and experimental therapeutics. vol 265. issue 2. 1993-06-22. PMID:8098761. |
in contrast to (-)pindolol (8.0 mg/kg s.c.), administration of (-)penbutolol (2.0 or 8.0 mg/kg s.c.) increased hippocampal 5-ht output. |
1993-06-22 |
2023-08-12 |
Not clear |
| N Andrews, N M Barnes, L J Steward, K E West, J Cunningham, P Y Wu, H Zangrossi, S E Fil. A comparison of rat brain amino acid and monoamine content in diazepam withdrawal and after exposure to a phobic stimulus. British journal of pharmacology. vol 109. issue 1. 1993-06-21. PMID:8495238. |
the content of amino acids (taurine, glycine, glutamic acid, gamma-aminobutyric acid (gaba) and aspartic acid) and monoamines (5-hydroxytryptamine (5-ht), 5-hydroxyindoleacetic acid (5-hiaa) and noradrenaline) in homogenates of rat cortical and hippocampal tissue were measured by high performance liquid chromatography (h.p.l.c.) |
1993-06-21 |
2023-08-12 |
rat |
| N Andrews, N M Barnes, L J Steward, K E West, J Cunningham, P Y Wu, H Zangrossi, S E Fil. A comparison of rat brain amino acid and monoamine content in diazepam withdrawal and after exposure to a phobic stimulus. British journal of pharmacology. vol 109. issue 1. 1993-06-21. PMID:8495238. |
in the group withdrawn from chronic diazepam, cortical 5-ht and 5-hiaa levels and hippocampal 5-ht levels were significantly increased. |
1993-06-21 |
2023-08-12 |
rat |
| N Andrews, N M Barnes, L J Steward, K E West, J Cunningham, P Y Wu, H Zangrossi, S E Fil. A comparison of rat brain amino acid and monoamine content in diazepam withdrawal and after exposure to a phobic stimulus. British journal of pharmacology. vol 109. issue 1. 1993-06-21. PMID:8495238. |
the changes in 5-ht and 5-hiaa levels following cat odour exposure were area-specific in that they decreased in the hippocampus, but increased in the cortex. |
1993-06-21 |
2023-08-12 |
rat |
| R C Arora, A Gulati, J W Crayto. Aging and 3H-paroxetine binding in rat brain: effect of imipramine and tetrahydroacridine. Life sciences. vol 52. issue 22. 1993-06-17. PMID:8492639. |
these observations suggest that the number of 5-ht transporter sites in the hippocampus increases with brain maturity but then drops significantly during old age. |
1993-06-17 |
2023-08-12 |
rat |
| F Villani, D Johnsto. Serotonin inhibits induction of long-term potentiation at commissural synapses in hippocampus. Brain research. vol 606. issue 2. 1993-06-14. PMID:8387861. |
serotonin inhibits induction of long-term potentiation at commissural synapses in hippocampus. |
1993-06-14 |
2023-08-12 |
rat |
| P E Ceccaldi, M P Fillion, A Ermine, H Tsiang, G Fillio. Rabies virus selectively alters 5-HT1 receptor subtypes in rat brain. European journal of pharmacology. vol 245. issue 2. 1993-06-14. PMID:8491253. |
the results of the present study show that, 5 days after rabies virus infection in rat, the total reversible high-affinity binding of [3h]5-ht in the hippocampus is not affected, suggesting that 5-ht1a binding is not altered. |
1993-06-14 |
2023-08-12 |
rat |
| J H Trouvin, A M Gardier, E Chanut, N Pages, C Jacquo. Time course of brain serotonin metabolism after cessation of long-term fluoxetine treatment in the rat. Life sciences. vol 52. issue 18. 1993-06-03. PMID:7683363. |
the effects of repeated fluoxetine (flx) administration (5, 10, or 15 mg/kg i.p., twice daily for 21 days) on serotonin and 5-hiaa metabolism were examined in the hypothalamus, hippocampus, pons medulla and cerebral cortex of rats killed 1-28 days after the last dose. |
1993-06-03 |
2023-08-12 |
rat |
| T Ohue, K Koshimura, Y Takagi, Y Watanabe, S Miwa, T Masak. Enhancement of acetylcholine release in the hippocampus by 6R-L-erythro-5,6,7,8-tetrahydrobiopterin is mediated by 5-hydroxytryptamine. Brain research. vol 607. issue 1-2. 1993-06-03. PMID:8097665. |
enhancement of acetylcholine release in the hippocampus by 6r-l-erythro-5,6,7,8-tetrahydrobiopterin is mediated by 5-hydroxytryptamine. |
1993-06-03 |
2023-08-12 |
rat |
| T Ohue, K Koshimura, Y Takagi, Y Watanabe, S Miwa, T Masak. Enhancement of acetylcholine release in the hippocampus by 6R-L-erythro-5,6,7,8-tetrahydrobiopterin is mediated by 5-hydroxytryptamine. Brain research. vol 607. issue 1-2. 1993-06-03. PMID:8097665. |
recently, we reported that 6r-l-erythro-tetrahydrobiopterin (6r-bh4), a natural cofactor for l-aromatic amino acid hydroxylases, enhances in vivo release of acetylcholine (ach) in the rat hippocampus: the enhancement was abolished after depletion of brain catecholamines and 5-hydroxytryptamine (5-ht) by pretreatment with reserpine. |
1993-06-03 |
2023-08-12 |
rat |
| T Ohue, K Koshimura, Y Takagi, Y Watanabe, S Miwa, T Masak. Enhancement of acetylcholine release in the hippocampus by 6R-L-erythro-5,6,7,8-tetrahydrobiopterin is mediated by 5-hydroxytryptamine. Brain research. vol 607. issue 1-2. 1993-06-03. PMID:8097665. |
administration of 6r-bh4 increased hippocampal 5-ht release, as indicated by increased extracellular levels of the major 5-ht metabolite, 5-hydroxyindoleacetic acid. |
1993-06-03 |
2023-08-12 |
rat |
| T Ohue, K Koshimura, Y Takagi, Y Watanabe, S Miwa, T Masak. Enhancement of acetylcholine release in the hippocampus by 6R-L-erythro-5,6,7,8-tetrahydrobiopterin is mediated by 5-hydroxytryptamine. Brain research. vol 607. issue 1-2. 1993-06-03. PMID:8097665. |
these results suggest that 6r-bh4 stimulates ach release in the hippocampus, mainly by augmenting release of 5-ht, a potent stimulator of ach release, and partly by augmenting release of da. |
1993-06-03 |
2023-08-12 |
rat |
| J M Abadie, B Wright, G Correa, E S Browne, J R Porter, F Sve. Effect of dehydroepiandrosterone on neurotransmitter levels and appetite regulation of the obese Zucker rat. The Obesity Research Program. Diabetes. vol 42. issue 5. 1993-05-28. PMID:7683287. |
the hypothalamus, frontal cortex, striatum, and hippocampus of dehydroepiandrosterone-treated animals were assayed for neurotransmitters known to have inhibitory or stimulatory effects on feeding behavior (serotonin, dopamine, norepinephrine, and epinephrine). |
1993-05-28 |
2023-08-12 |
rat |
| R Mongeau, P Blier, C de Montign. In vivo electrophysiological evidence for tonic activation by endogenous noradrenaline of alpha 2-adrenoceptors on 5-hydroxytryptamine terminals in the rat hippocampus. Naunyn-Schmiedeberg's archives of pharmacology. vol 347. issue 3. 1993-05-27. PMID:8097564. |
in vivo electrophysiological evidence for tonic activation by endogenous noradrenaline of alpha 2-adrenoceptors on 5-hydroxytryptamine terminals in the rat hippocampus. |
1993-05-27 |
2023-08-12 |
rat |