| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lei An, You-Zhi Zhang, Neng-Jiang Yu, Xin-Min Liu, Nan Zhao, Li Yuan, Yun-Feng L. Role for serotonin in the antidepressant-like effect of a flavonoid extract of Xiaobuxin-Tang. Pharmacology, biochemistry, and behavior. vol 89. issue 4. 2008-08-06. PMID:18367239. |
furthermore, xbxt-2 normalized the neurotransmitter changes, including the decreased serotonin (5-ht) and its metabolite 5-hydroxyindoleacetic acid (5-hiaa) levels in hippocampus and prefrontal cortex in cms rats. |
2008-08-06 |
2023-08-12 |
mouse |
| M Morales, K Hein, Z Voge. Hippocampal interneurons co-express transcripts encoding the alpha7 nicotinic receptor subunit and the cannabinoid receptor 1. Neuroscience. vol 152. issue 1. 2008-08-05. PMID:18222041. |
since it is well established that the vast majority of hippocampal interneurons expressing cb1 mrna have 5-ht type 3 (5-ht3) receptors, we conclude that these hippocampal alpha7 nach/5ht3/cb1/cck interneurons correspond to those previously postulated to relay inputs from diverse cortical and subcortical regions about emotional, motivational, and physiological states. |
2008-08-05 |
2023-08-12 |
rat |
| Mohammad Tariq, Mohammad Ahmad, Khalaf Al Moutaery, Saleh Al Dee. Pentoxifylline ameliorates lithium-pilocarpine induced status epilepticus in young rats. Epilepsy & behavior : E&B. vol 12. issue 3. 2008-07-30. PMID:18203664. |
the neuroprotective activity of ptx was accompanied by reduction in oxidative stress and reversal of se-induced depletion of dopamine and 5-hydroxytryptamine in hippocampus and striatum. |
2008-07-30 |
2023-08-12 |
rat |
| Ilse Smolders, Ralph Clinckers, Alfred Meurs, Dimitri De Bundel, Jeanelle Portelli, Guy Ebinger, Yvette Michott. Direct enhancement of hippocampal dopamine or serotonin levels as a pharmacodynamic measure of combined antidepressant-anticonvulsant action. Neuropharmacology. vol 54. issue 6. 2008-07-22. PMID:18378264. |
direct enhancement of hippocampal dopamine or serotonin levels as a pharmacodynamic measure of combined antidepressant-anticonvulsant action. |
2008-07-22 |
2023-08-12 |
mouse |
| Ilse Smolders, Ralph Clinckers, Alfred Meurs, Dimitri De Bundel, Jeanelle Portelli, Guy Ebinger, Yvette Michott. Direct enhancement of hippocampal dopamine or serotonin levels as a pharmacodynamic measure of combined antidepressant-anticonvulsant action. Neuropharmacology. vol 54. issue 6. 2008-07-22. PMID:18378264. |
we here studied whether anticonvulsant compounds are antidepressant and can elevate hippocampal dopamine (da) or serotonin (5-ht) levels determined by in vivo microdialysis in rats. |
2008-07-22 |
2023-08-12 |
mouse |
| Ilse Smolders, Ralph Clinckers, Alfred Meurs, Dimitri De Bundel, Jeanelle Portelli, Guy Ebinger, Yvette Michott. Direct enhancement of hippocampal dopamine or serotonin levels as a pharmacodynamic measure of combined antidepressant-anticonvulsant action. Neuropharmacology. vol 54. issue 6. 2008-07-22. PMID:18378264. |
these compounds with combined antidepressant-anticonvulsant properties all directly enhanced extracellular hippocampal da or 5-ht levels. |
2008-07-22 |
2023-08-12 |
mouse |
| Ilse Smolders, Ralph Clinckers, Alfred Meurs, Dimitri De Bundel, Jeanelle Portelli, Guy Ebinger, Yvette Michott. Direct enhancement of hippocampal dopamine or serotonin levels as a pharmacodynamic measure of combined antidepressant-anticonvulsant action. Neuropharmacology. vol 54. issue 6. 2008-07-22. PMID:18378264. |
since glutamate-mediated hyperexcitability in temporal lobe regions seems to be involved in disturbed emotional behaviour, we next investigated possible antidepressant effects and hippocampal da or 5-ht modulations exerted by selective ionotropic and metabotropic glutamate receptor ligands with anticonvulsant properties. |
2008-07-22 |
2023-08-12 |
mouse |
| Ilse Smolders, Ralph Clinckers, Alfred Meurs, Dimitri De Bundel, Jeanelle Portelli, Guy Ebinger, Yvette Michott. Direct enhancement of hippocampal dopamine or serotonin levels as a pharmacodynamic measure of combined antidepressant-anticonvulsant action. Neuropharmacology. vol 54. issue 6. 2008-07-22. PMID:18378264. |
combined anticonvulsant-antidepressant activities of the nmda antagonist mk-801 and the mglur group i antagonists (aida, mpep) were also associated with locally elicited increases in hippocampal da and/or 5-ht levels. |
2008-07-22 |
2023-08-12 |
mouse |
| Céline Riegert, Anna Katharina Rothmaier, Jost Leemhuis, Timothy J Sexton, John F Neumaier, Jean-Christophe Cassel, Rolf Jackisc. Increased expression of 5-HT(1B) receptors by Herpes simplex virus gene transfer in septal neurons: New in vitro and in vivo models to study 5-HT(1B) receptor function. Brain research bulletin. vol 76. issue 4. 2008-07-16. PMID:18502320. |
three days later, electrically evoked release of ach in hippocampal slices of ha1b/gfp-treated rats was lower than in their gfp-treated counterparts, showing a higher inhibitory efficacy of endogenous 5-ht on cholinergic terminals after transfection. |
2008-07-16 |
2023-08-12 |
rat |
| Hsiun-Ing Chen, Li-Chun Lin, Lung Yu, Yu-Fan Liu, Yu-Min Kuo, A-Min Huang, Jih-Ing Chuang, Fong-Sen Wu, Pao-Chi Liao, Chauying J Je. Treadmill exercise enhances passive avoidance learning in rats: the role of down-regulated serotonin system in the limbic system. Neurobiology of learning and memory. vol 89. issue 4. 2008-07-15. PMID:17892954. |
we examined the effects of 4-week treadmill exercise training on levels of 5-ht and its metabolite 5-hydroxyindoleacetic acid (5-hiaa), the protein expression of its receptor 5-ht(1a) and transporter in the amygdala, hippocampus and prefrontal cortex of male sprague-dawley rats. |
2008-07-15 |
2023-08-12 |
rat |
| Hsiun-Ing Chen, Li-Chun Lin, Lung Yu, Yu-Fan Liu, Yu-Min Kuo, A-Min Huang, Jih-Ing Chuang, Fong-Sen Wu, Pao-Chi Liao, Chauying J Je. Treadmill exercise enhances passive avoidance learning in rats: the role of down-regulated serotonin system in the limbic system. Neurobiology of learning and memory. vol 89. issue 4. 2008-07-15. PMID:17892954. |
our results demonstrated that treadmill exercise (1) improved the passive avoidance learning performance; (2) decreased the 5-ht level in the hippocampus; (3) decreased the expression of 5-ht(1a) receptor in the amygdala without altering the transporter expression. |
2008-07-15 |
2023-08-12 |
rat |
| Hsiun-Ing Chen, Li-Chun Lin, Lung Yu, Yu-Fan Liu, Yu-Min Kuo, A-Min Huang, Jih-Ing Chuang, Fong-Sen Wu, Pao-Chi Liao, Chauying J Je. Treadmill exercise enhances passive avoidance learning in rats: the role of down-regulated serotonin system in the limbic system. Neurobiology of learning and memory. vol 89. issue 4. 2008-07-15. PMID:17892954. |
our results suggest that down-regulation of the 5-ht system in the limbic system, i.e., the reduction of the hippocampus 5-ht content and the amygdala 5-ht(1a) receptor expression, may be involved in the exercise-enhanced fear memory. |
2008-07-15 |
2023-08-12 |
rat |
| Katsunori Kobayashi, Yumiko Ikeda, Eisuke Haneda, Hidenori Suzuk. Chronic fluoxetine bidirectionally modulates potentiating effects of serotonin on the hippocampal mossy fiber synaptic transmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 24. 2008-07-10. PMID:18550770. |
chronic fluoxetine bidirectionally modulates potentiating effects of serotonin on the hippocampal mossy fiber synaptic transmission. |
2008-07-10 |
2023-08-12 |
mouse |
| Katsunori Kobayashi, Yumiko Ikeda, Eisuke Haneda, Hidenori Suzuk. Chronic fluoxetine bidirectionally modulates potentiating effects of serotonin on the hippocampal mossy fiber synaptic transmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 24. 2008-07-10. PMID:18550770. |
here, we show that serotonin potentiates synaptic transmission between mossy fibers, the sole output of the dentate granule cells, and ca3 pyramidal cells in mouse hippocampal slices. |
2008-07-10 |
2023-08-12 |
mouse |
| Katsunori Kobayashi, Yumiko Ikeda, Eisuke Haneda, Hidenori Suzuk. Chronic fluoxetine bidirectionally modulates potentiating effects of serotonin on the hippocampal mossy fiber synaptic transmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 24. 2008-07-10. PMID:18550770. |
exposure of mice to novel environments induces increases in locomotor activity and hippocampal extracellular 5-ht levels. |
2008-07-10 |
2023-08-12 |
mouse |
| C J Peddie, H A Davies, F M Colyer, M G Stewart, J J Rodrígue. Colocalisation of serotonin2A receptors with the glutamate receptor subunits NR1 and GluR2 in the dentate gyrus: an ultrastructural study of a modulatory role. Experimental neurology. vol 211. issue 2. 2008-07-07. PMID:18439999. |
the serotonin(2a) receptor (5-ht(2a)r) is implicated in many neurological disorders and has a role in cognitive processes, reliant upon hippocampal glutamate receptors. |
2008-07-07 |
2023-08-12 |
Not clear |
| C J Peddie, H A Davies, F M Colyer, M G Stewart, J J Rodrígue. Colocalisation of serotonin2A receptors with the glutamate receptor subunits NR1 and GluR2 in the dentate gyrus: an ultrastructural study of a modulatory role. Experimental neurology. vol 211. issue 2. 2008-07-07. PMID:18439999. |
recent studies show that 5-ht(2a)r agonists and/or antagonists can influence cognitive function, suggesting a critical hippocampal role for these receptors, yet their cellular and subcellular distribution within this region has not been comprehensively analysed. |
2008-07-07 |
2023-08-12 |
Not clear |
| C J Peddie, H A Davies, F M Colyer, M G Stewart, J J Rodrígue. Colocalisation of serotonin2A receptors with the glutamate receptor subunits NR1 and GluR2 in the dentate gyrus: an ultrastructural study of a modulatory role. Experimental neurology. vol 211. issue 2. 2008-07-07. PMID:18439999. |
here, we have conducted an electron microscopic examination of 5-ht(2a)r distribution with the glutamate n-methyl-d-aspartate (nmda) and amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid (ampa) receptor subunits nr1 and glur2 in the hippocampal dentate gyrus (dg) in order to investigate whether 5-ht(2a)r location is compatible with a modulatory role over nmda and/or ampa receptor mediated neurotransmission. |
2008-07-07 |
2023-08-12 |
Not clear |
| Marie Cahir, Tara C Ardis, Jennifer J Elliott, Christopher B Kelly, Gavin P Reynolds, Stephen J Coope. Acute tryptophan depletion does not alter central or plasma brain-derived neurotrophic factor in the rat. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 18. issue 5. 2008-07-02. PMID:17719210. |
atd significantly reduced free-plasma trp by 79% and central hippocampal 5-ht by 35% when compared to controls. |
2008-07-02 |
2023-08-12 |
human |
| Qun Xu, Li-Tao Yi, Ying Pan, Xing Wang, Yu-Cheng Li, Jian-Mei Li, Cai-Ping Wang, Ling-Dong Kon. Antidepressant-like effects of the mixture of honokiol and magnolol from the barks of Magnolia officinalis in stressed rodents. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 3. 2008-07-02. PMID:18093712. |
the mixture of honokiol and magnolol at 20 and 40 mg/kg significantly attenuated cms-induced decreases of 5-ht levels in frontal cortex, hippocampus, striatum, hypothalamus and nucleus accumbens. |
2008-07-02 |
2023-08-12 |
mouse |