| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D D Luo, S C An, X Zhan. Involvement of hippocampal serotonin and neuropeptide Y in depression induced by chronic unpredicted mild stress. Brain research bulletin. vol 77. issue 1. 2008-09-11. PMID:18579108. |
accumulated evidence indicates a role of the hippocampal 5-hydroxy-tryptamine (5-ht) and neuropeptide y (npy) in the response to stress and modulation of depression, but it is unclear whether and how the hippocampal 5-ht and npy systems make contributions to chronic unpredicted mild stress (cums)-induced depression. |
2008-09-11 |
2023-08-12 |
rat |
| D D Luo, S C An, X Zhan. Involvement of hippocampal serotonin and neuropeptide Y in depression induced by chronic unpredicted mild stress. Brain research bulletin. vol 77. issue 1. 2008-09-11. PMID:18579108. |
these data suggest a critical role of reduced hippocampal 5-ht and npy neurotransmission in cums-induced depression. |
2008-09-11 |
2023-08-12 |
rat |
| Efrain C Azmitia, Ralph Nixo. Dystrophic serotonergic axons in neurodegenerative diseases. Brain research. vol 1217. 2008-09-09. PMID:18502405. |
in neuropathologically normal (control) brains (n=3), serotonin axons immunoreactive (ir) with antibodies against the serotonin transporter (5-htt) protein were widely distributed in cortex (entorhinal and dorsolateral prefrontal), hippocampus and rostral brainstem. |
2008-09-09 |
2023-08-12 |
human |
| Saloua Benmansour, Thierry Deltheil, Jonathan Piotrowski, Lorelei Nicolas, Christelle Reperant, Alain M Gardier, Alan Frazer, Denis J Davi. Influence of brain-derived neurotrophic factor (BDNF) on serotonin neurotransmission in the hippocampus of adult rodents. European journal of pharmacology. vol 587. issue 1-3. 2008-08-25. PMID:18474368. |
influence of brain-derived neurotrophic factor (bdnf) on serotonin neurotransmission in the hippocampus of adult rodents. |
2008-08-25 |
2023-08-12 |
mouse |
| Saloua Benmansour, Thierry Deltheil, Jonathan Piotrowski, Lorelei Nicolas, Christelle Reperant, Alain M Gardier, Alan Frazer, Denis J Davi. Influence of brain-derived neurotrophic factor (BDNF) on serotonin neurotransmission in the hippocampus of adult rodents. European journal of pharmacology. vol 587. issue 1-3. 2008-08-25. PMID:18474368. |
a single bdnf injection (either intracerebroventricularly or directly into the ca3 region of hippocampus) decreased the signal amplitude and clearance rate produced by exogenously applied 5-ht compared to what was measured in control rats, shown using in vivo chronoamperometry. |
2008-08-25 |
2023-08-12 |
mouse |
| Saloua Benmansour, Thierry Deltheil, Jonathan Piotrowski, Lorelei Nicolas, Christelle Reperant, Alain M Gardier, Alan Frazer, Denis J Davi. Influence of brain-derived neurotrophic factor (BDNF) on serotonin neurotransmission in the hippocampus of adult rodents. European journal of pharmacology. vol 587. issue 1-3. 2008-08-25. PMID:18474368. |
in awake freely moving mice, acute intrahippocampal injection of bdnf decreased extracellular levels of 5-ht in the hippocampus, as measured using microdialysis. |
2008-08-25 |
2023-08-12 |
mouse |
| V S Naumenko, S E Tkachev, A V Kulikov, T P Semenova, Z G Amerhanov, N P Smirnova, N K Popov. The brain 5-HT1A receptor gene expression in hibernation. Genes, brain, and behavior. vol 7. issue 3. 2008-08-18. PMID:17711450. |
an increase in the 5-ht(1a) gene expression was found in the hippocampus during the prehibernation period and in ground squirrels coming out of hibernation, thus confirming the idea of the hippocampus trigger role in the hibernation. |
2008-08-18 |
2023-08-12 |
mouse |
| Hiroko Hagiwara, Yuko Fujita, Tamaki Ishima, Shinsui Kunitachi, Yukihiko Shirayama, Masaomi Iyo, Kenji Hashimot. Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the antipsychotic drug perospirone: role of serotonin 5-HT1A receptors. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 18. issue 6. 2008-08-13. PMID:18164909. |
moreover, a receptor binding assay using [(3)h]way100635 revealed that levels of 5-ht(1a) receptors in the hippocampus, but not in the frontal cortex, of pcp-treated mice were significantly lower than those of saline-treated mice. |
2008-08-13 |
2023-08-12 |
mouse |
| Thierry Deltheil, Bruno P Guiard, Jean-Philippe Guilloux, Lorelei Nicolas, Claudine Deloménie, Christelle Repérant, Erwan Le Maitre, Isabelle Leroux-Nicollet, Saloua Benmansour, François Coudoré, Denis J David, Alain M Gardie. Consequences of changes in BDNF levels on serotonin neurotransmission, 5-HT transporter expression and function: studies in adult mice hippocampus. Pharmacology, biochemistry, and behavior. vol 90. issue 2. 2008-08-12. PMID:17980409. |
consequences of changes in bdnf levels on serotonin neurotransmission, 5-ht transporter expression and function: studies in adult mice hippocampus. |
2008-08-12 |
2023-08-12 |
mouse |
| Thierry Deltheil, Bruno P Guiard, Jean-Philippe Guilloux, Lorelei Nicolas, Claudine Deloménie, Christelle Repérant, Erwan Le Maitre, Isabelle Leroux-Nicollet, Saloua Benmansour, François Coudoré, Denis J David, Alain M Gardie. Consequences of changes in BDNF levels on serotonin neurotransmission, 5-HT transporter expression and function: studies in adult mice hippocampus. Pharmacology, biochemistry, and behavior. vol 90. issue 2. 2008-08-12. PMID:17980409. |
indeed, although the elevation of 5-ht outflow induced by chronic administration of selective serotonin reuptake inhibitors (ssris) causes an increase in bdnf protein levels and expression (mrna) in the hippocampus of rodents, the reciprocal interaction has not been demonstrated yet. |
2008-08-12 |
2023-08-12 |
mouse |
| Thierry Deltheil, Bruno P Guiard, Jean-Philippe Guilloux, Lorelei Nicolas, Claudine Deloménie, Christelle Repérant, Erwan Le Maitre, Isabelle Leroux-Nicollet, Saloua Benmansour, François Coudoré, Denis J David, Alain M Gardie. Consequences of changes in BDNF levels on serotonin neurotransmission, 5-HT transporter expression and function: studies in adult mice hippocampus. Pharmacology, biochemistry, and behavior. vol 90. issue 2. 2008-08-12. PMID:17980409. |
thus, the neurochemical sight of this question will be addressed here by examining the consequences of either a constitutive decrease or increase in brain bdnf protein levels on hippocampal extracellular levels of 5-ht in conscious mice. |
2008-08-12 |
2023-08-12 |
mouse |
| Astrid C E Linthorst, Johannes M Reu. Stress and the brain: solving the puzzle using microdialysis. Pharmacology, biochemistry, and behavior. vol 90. issue 2. 2008-08-12. PMID:18028991. |
here we review the effects of acute and chronic stress on serotonin and gaba, as assessed by microdialysis, in the hippocampus; a brain structure critically involved in the behavioural and neuroendocrine responses to stress. |
2008-08-12 |
2023-08-12 |
human |
| Astrid C E Linthorst, Johannes M Reu. Stress and the brain: solving the puzzle using microdialysis. Pharmacology, biochemistry, and behavior. vol 90. issue 2. 2008-08-12. PMID:18028991. |
from the microdialysis data discussed, it can be concluded that both serotonin and gaba in the hippocampus are highly responsive to stress, but also that these responses are shaped by the exact nature of the stressor, i.e. |
2008-08-12 |
2023-08-12 |
human |
| D Christin, S Daulon, S Delamanche, N Perrier, P Breton, L Tayss. Effects of repeated low-dose soman exposure on monoamine levels in different brain structures in mice. Neurochemical research. vol 33. issue 5. 2008-08-11. PMID:17994275. |
this study provides the first evidence of a modification of the 5-ht turnover in the hippocampus and the striatum after repeated low-dose intoxication with a nerve agent. |
2008-08-11 |
2023-08-12 |
mouse |
| Pei-Ju Chen, Ching-Liang Hsieh, Kuan-Pin Su, Yu-Chi Hou, Hsiu-Mei Chiang, I-Hsin Lin, Lee-Yan Shee. The antidepressant effect of Gastrodia elata Bl. on the forced-swimming test in rats. The American journal of Chinese medicine. vol 36. issue 1. 2008-08-11. PMID:18306453. |
the concentration of serotonin (5-ht), 5-hydroxyindoleacetic acid (5-hiaa), and the ratio of 5-hiaa/5-ht in frontal cortex, amygdala, and hippocampus were not significantly different between ge and the control groups. |
2008-08-11 |
2023-08-12 |
rat |
| Guillaume Lucas, Vladimir V Rymar, Abbas F Sadikot, Guy Debonne. Further evidence for an antidepressant potential of the selective sigma1 agonist SA 4503: electrophysiological, morphological and behavioural studies. The international journal of neuropsychopharmacology. vol 11. issue 4. 2008-08-08. PMID:18364064. |
we focused more specifically on the influence of sa 4503 on central serotonergic (5-ht) transmission, and on hippocampal cell proliferation. |
2008-08-08 |
2023-08-12 |
Not clear |
| Darrick T Balu, Brian A Hoshaw, Jessica E Malberg, Sharon Rosenzweig-Lipson, Lee E Schechter, Irwin Luck. Differential regulation of central BDNF protein levels by antidepressant and non-antidepressant drug treatments. Brain research. vol 1211. 2008-08-08. PMID:18433734. |
chronic (21 days), but not acute (1 day), treatment with the tricyclic antidepressant (tca) desipramine (10 mg/kg), the selective serotonin reuptake inhibitor (ssri) fluoxetine (10 mg/kg), and the monoamine oxidase inhibitor (maoi) phenelzine (10 mg/kg) increased bdnf protein levels in the frontal cortex (10-30%), but not in the hippocampus, amygdala, olfactory bulb, and brain stem. |
2008-08-08 |
2023-08-12 |
rat |
| Lee E Schechter, Qian Lin, Deborah L Smith, Guoming Zhang, Qin Shan, Brian Platt, Michael R Brandt, Lee A Dawson, Derek Cole, Ron Bernotas, Albert Robichaud, Sharon Rosenzweig-Lipson, Chad E Beye. Neuropharmacological profile of novel and selective 5-HT6 receptor agonists: WAY-181187 and WAY-208466. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 6. 2008-08-07. PMID:17625499. |
in the dorsal hippocampus, striatum, and amygdala, way-181187 (10-30 mg/kg, s.c.) elicited robust elevations in extracellular levels of gaba without producing similar effects on concentrations of norepinephrine, serotonin, dopamine, or glutamate. |
2008-08-07 |
2023-08-12 |
human |
| Lee E Schechter, Qian Lin, Deborah L Smith, Guoming Zhang, Qin Shan, Brian Platt, Michael R Brandt, Lee A Dawson, Derek Cole, Ron Bernotas, Albert Robichaud, Sharon Rosenzweig-Lipson, Chad E Beye. Neuropharmacological profile of novel and selective 5-HT6 receptor agonists: WAY-181187 and WAY-208466. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 6. 2008-08-07. PMID:17625499. |
in hippocampal slice preparations (in vitro), 5-ht(6) receptor agonism attenuated stimulated glutamate levels elicited by sodium azide and high kcl treatment. |
2008-08-07 |
2023-08-12 |
human |
| Boris Mlinar, Simona Mascalchi, Raffaella Morini, Filippo Giachi, Renato Corradett. MDMA induces EPSP-Spike potentiation in rat ventral hippocampus in vitro via serotonin and noradrenaline release and coactivation of 5-HT4 and beta1 receptors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 6. 2008-08-07. PMID:17653110. |
mdma induces epsp-spike potentiation in rat ventral hippocampus in vitro via serotonin and noradrenaline release and coactivation of 5-ht4 and beta1 receptors. |
2008-08-07 |
2023-08-12 |
human |