| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I G Sil'ki. [Characteristics of the hippocampal formation functioning during wakefulness and paradoxical sleep]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 58. issue 3. 2008-10-10. PMID:18689238. |
in view of the available published data concerning various concentration of neuromodulators in the brain during paradoxical sleep and wakefulness and the evidence for the influences of neuromodulators on efficiency of synaptic inputs to hippocampal neurons it is concluded that during paradoxical sleep, increase in concentrations of acetylcholine, cortisol, and dopamine and simultaneous decrease in serotonin and noradrenaline levels could synergistically lead to essential depression of efficacy of synaptic transmission in the polysynaptic pathway through the hippocampus (i.e. |
2008-10-10 |
2023-08-12 |
Not clear |
| Rolf Jackisch, Simon Gansser, Jean-Christophe Casse. Noradrenergic denervation facilitates the release of acetylcholine and serotonin in the hippocampus: towards a mechanism underlying upregulations described in MCI patients? Experimental neurology. vol 213. issue 2. 2008-10-08. PMID:18625224. |
noradrenergic denervation facilitates the release of acetylcholine and serotonin in the hippocampus: towards a mechanism underlying upregulations described in mci patients? |
2008-10-08 |
2023-08-12 |
rat |
| Rolf Jackisch, Simon Gansser, Jean-Christophe Casse. Noradrenergic denervation facilitates the release of acetylcholine and serotonin in the hippocampus: towards a mechanism underlying upregulations described in MCI patients? Experimental neurology. vol 213. issue 2. 2008-10-08. PMID:18625224. |
dsp-4 treatment reduced hippocampal noradrenaline (na) by more than 90% (vs. controls), whereas dopamine and 5-ht levels were unaffected. |
2008-10-08 |
2023-08-12 |
rat |
| Akiyoshi Saitoh, Mitsuhiko Yamada, Misa Yamada, Kou Takahashi, Kazumasa Yamaguchi, Hiroyasu Murasawa, Akiko Nakatani, Yoshimi Tatsumi, Noritaka Hirose, Junzo Kame. Antidepressant-like effects of the delta-opioid receptor agonist SNC80 ([(+)-4-[(alphaR)-alpha-[(2S,5R)-2,5-dimethyl-4-(2-propenyl)-1-piperazinyl]-(3-methoxyphenyl)methyl]-N,N-diethylbenzamide) in an olfactory bulbectomized rat model. Brain research. vol 1208. 2008-10-02. PMID:18381208. |
moreover, the concentration of 5-ht and its metabolite 5-hiaa in the frontal cortex, hippocampus, and amygdala were decreased in obx rats, and these changes were also normalized by snc80 treatment, rather than desipramine treatment. |
2008-10-02 |
2023-08-12 |
rat |
| Pablo Salazar-Colocho, Joaquín Del Río, Diana Frechill. Neuroprotective effects of serotonin 5-HT 1A receptor activation against ischemic cell damage in gerbil hippocampus: Involvement of NMDA receptor NR1 subunit and BDNF. Brain research. vol 1199. 2008-09-29. PMID:18269931. |
neuroprotective effects of serotonin 5-ht 1a receptor activation against ischemic cell damage in gerbil hippocampus: involvement of nmda receptor nr1 subunit and bdnf. |
2008-09-29 |
2023-08-12 |
Not clear |
| Pablo Salazar-Colocho, Joaquín Del Río, Diana Frechill. Neuroprotective effects of serotonin 5-HT 1A receptor activation against ischemic cell damage in gerbil hippocampus: Involvement of NMDA receptor NR1 subunit and BDNF. Brain research. vol 1199. 2008-09-29. PMID:18269931. |
nmda receptor nr1 levels in whole hippocampus were not affected 24 h after ischemia, but the levels of the subunit phosphorylated at the protein kinase a (pka) site, pnr1(ser897), were significantly increased, and this increase was prevented by the same 8-oh-dpat dose, a probable consequence of the increased phosphatase 1 (pp1) enzyme activity found in ischemic gerbils pretreated with the 5-ht(1a) receptor agonist. |
2008-09-29 |
2023-08-12 |
Not clear |
| Naila Rasheed, Ethika Tyagi, Ausaf Ahmad, Kiran Babu Siripurapu, Shawon Lahiri, Rakesh Shukla, Gautam Pali. Involvement of monoamines and proinflammatory cytokines in mediating the anti-stress effects of Panax quinquefolium. Journal of ethnopharmacology. vol 117. issue 2. 2008-09-26. PMID:18339495. |
the present study explores the effects of pq on stress induced changes of corticosterone level in plasma, monoamines (na, da and 5-ht) and interleukin (il-2 and il-6) levels in cortex and hippocampus regions of brain and also indicate their possible roles in modulating stress. |
2008-09-26 |
2023-08-12 |
mouse |
| Naila Rasheed, Ethika Tyagi, Ausaf Ahmad, Kiran Babu Siripurapu, Shawon Lahiri, Rakesh Shukla, Gautam Pali. Involvement of monoamines and proinflammatory cytokines in mediating the anti-stress effects of Panax quinquefolium. Journal of ethnopharmacology. vol 117. issue 2. 2008-09-26. PMID:18339495. |
mice subjected to chronic unpredictable stress (cus, for 7 days) showed significant increase in plasma corticosterone level and depletion of noradrenaline (na), dopamine (da) and 5-hydroxytryptamine (5-ht) levels in cortex and hippocampal regions along with an increased level of il-2 and il-6 in the same areas. |
2008-09-26 |
2023-08-12 |
mouse |
| Naila Rasheed, Ethika Tyagi, Ausaf Ahmad, Kiran Babu Siripurapu, Shawon Lahiri, Rakesh Shukla, Gautam Pali. Involvement of monoamines and proinflammatory cytokines in mediating the anti-stress effects of Panax quinquefolium. Journal of ethnopharmacology. vol 117. issue 2. 2008-09-26. PMID:18339495. |
moreover, it was significantly effective in reinstating the cus induced depletion of na, da and 5-ht in hippocampus, while na and 5-ht in cortex of brain. |
2008-09-26 |
2023-08-12 |
mouse |
| Sally Martin, Maarten van den Buus. Phencyclidine-induced locomotor hyperactivity is enhanced in mice after stereotaxic brain serotonin depletion. Behavioural brain research. vol 191. issue 2. 2008-09-24. PMID:18482774. |
lesioned mice showed a 68% depletion of serotonin in the hippocampus and 31% depletion in the striatum. |
2008-09-24 |
2023-08-12 |
mouse |
| Sally Martin, Maarten van den Buus. Phencyclidine-induced locomotor hyperactivity is enhanced in mice after stereotaxic brain serotonin depletion. Behavioural brain research. vol 191. issue 2. 2008-09-24. PMID:18482774. |
taken together with previous studies in rats, these studies in mice suggest that serotonin release in the dorsal hippocampus constitutes a behavioural inhibitory pathway normally involved in dampening excessive behavioural stimulation. |
2008-09-24 |
2023-08-12 |
mouse |
| Sigeng Chen, Geoffrey C Owens, David B Edelma. Dopamine inhibits mitochondrial motility in hippocampal neurons. PloS one. vol 3. issue 7. 2008-09-24. PMID:18665222. |
in an earlier study, we found that serotonin (5-ht), acting through the 5-ht1a receptor subtype, promotes axonal transport of mitochondria in cultured hippocampal neurons by increasing akt activity, and consequently decreasing glycogen synthase kinase (gsk3beta) activity. |
2008-09-24 |
2023-08-12 |
Not clear |
| M C Carvalho, S Masson, M L Brandão, M A de Souza Silv. Anxiolytic-like effects of substance P administration into the dorsal, but not ventral, hippocampus and its influence on serotonin. Peptides. vol 29. issue 7. 2008-09-22. PMID:18490080. |
anxiolytic-like effects of substance p administration into the dorsal, but not ventral, hippocampus and its influence on serotonin. |
2008-09-22 |
2023-08-12 |
rat |
| Patrycja Pitra, Krzysztof Tokarski, Małgorzata Grzegorzewska, Grzegorz Hes. Effects of repetitive administration of tianeptine, zinc hydroaspartate and electroconvulsive shock on the reactivity of 5-HT(7) receptors in rat hippocampus. Pharmacological reports : PR. vol 59. issue 6. 2008-09-17. PMID:18195451. |
effects of repetitive administration of tianeptine, zinc hydroaspartate and electroconvulsive shock on the reactivity of 5-ht(7) receptors in rat hippocampus. |
2008-09-17 |
2023-08-12 |
rat |
| Jin-Xia Dai, Hui-Li Han, Meng Tian, Jun Cao, Jian-Bo Xiu, Ning-Ning Song, Ying Huang, Tian-Le Xu, Yu-Qiang Ding, Lin X. Enhanced contextual fear memory in central serotonin-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 33. 2008-09-16. PMID:18695238. |
furthermore, bath application of 5-ht in 5-ht-deficient mice restored foot shock-induced alterations of hippocampal synaptic plasticity. |
2008-09-16 |
2023-08-12 |
mouse |
| Jin-Xia Dai, Hui-Li Han, Meng Tian, Jun Cao, Jian-Bo Xiu, Ning-Ning Song, Ying Huang, Tian-Le Xu, Yu-Qiang Ding, Lin X. Enhanced contextual fear memory in central serotonin-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 33. 2008-09-16. PMID:18695238. |
thus, central 5-ht regulates hippocampus-dependent contextual fear memory, and 5-ht modulation of hippocampal synaptic plasticity may be the underlying mechanism. |
2008-09-16 |
2023-08-12 |
mouse |
| Andréy Mazarati, Prabha Siddarth, Roger A Baldwin, Don Shin, Rochelle Caplan, Raman Sanka. Depression after status epilepticus: behavioural and biochemical deficits and effects of fluoxetine. Brain : a journal of neurology. vol 131. issue Pt 8. 2008-09-15. PMID:18559371. |
biochemical studies revealed compromised serotonergic transmission in the raphe-hippocampal serotonergic pathway: decrease of serotonin (5-ht) concentration and turnover in the hippocampus, measured by high performance liquid chromatography, and decrease of 5-ht release from the hippocampus in response to raphe stimulation, measured by fast cyclic voltammetry. |
2008-09-15 |
2023-08-12 |
rat |
| Andréy Mazarati, Prabha Siddarth, Roger A Baldwin, Don Shin, Rochelle Caplan, Raman Sanka. Depression after status epilepticus: behavioural and biochemical deficits and effects of fluoxetine. Brain : a journal of neurology. vol 131. issue Pt 8. 2008-09-15. PMID:18559371. |
administration of fluoxetine (flx, 20 mg/kg/day for 10 days) to naive animals significantly shortened immobility time under conditions of fst, and inhibited 5-ht turnover in the hippocampus. |
2008-09-15 |
2023-08-12 |
rat |
| Andréy Mazarati, Prabha Siddarth, Roger A Baldwin, Don Shin, Rochelle Caplan, Raman Sanka. Depression after status epilepticus: behavioural and biochemical deficits and effects of fluoxetine. Brain : a journal of neurology. vol 131. issue Pt 8. 2008-09-15. PMID:18559371. |
in post-se rats flx treatment led to a further decrease of hippocampal 5-ht turnover; however, performance in fst was not improved. |
2008-09-15 |
2023-08-12 |
rat |
| D D Luo, S C An, X Zhan. Involvement of hippocampal serotonin and neuropeptide Y in depression induced by chronic unpredicted mild stress. Brain research bulletin. vol 77. issue 1. 2008-09-11. PMID:18579108. |
involvement of hippocampal serotonin and neuropeptide y in depression induced by chronic unpredicted mild stress. |
2008-09-11 |
2023-08-12 |
rat |