| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jiansong Zhou, Lingjiang Li, Shaojun Tang, Xia Cao, Zexuan Li, Weihui Li, Changqi Li, Xianghui Zhan. Effects of serotonin depletion on the hippocampal GR/MR and BDNF expression during the stress adaptation. Behavioural brain research. vol 195. issue 1. 2009-01-12. PMID:18601957. |
effects of serotonin depletion on the hippocampal gr/mr and bdnf expression during the stress adaptation. |
2009-01-12 |
2023-08-12 |
rat |
| Jiansong Zhou, Lingjiang Li, Shaojun Tang, Xia Cao, Zexuan Li, Weihui Li, Changqi Li, Xianghui Zhan. Effects of serotonin depletion on the hippocampal GR/MR and BDNF expression during the stress adaptation. Behavioural brain research. vol 195. issue 1. 2009-01-12. PMID:18601957. |
increased serotonin (5-hydroxytryptamine, 5-ht) release in the hippocampus induced by repeated stress is thought to be critical for the neuroadaptation that alleviates the adverse effects of stressors on emotion and behavior. |
2009-01-12 |
2023-08-12 |
rat |
| Jiansong Zhou, Lingjiang Li, Shaojun Tang, Xia Cao, Zexuan Li, Weihui Li, Changqi Li, Xianghui Zhan. Effects of serotonin depletion on the hippocampal GR/MR and BDNF expression during the stress adaptation. Behavioural brain research. vol 195. issue 1. 2009-01-12. PMID:18601957. |
the para-chloroamphetamine (p-pca) was used to deplete 5-ht in the rat prior to repeated restraint stress (6h/day for 10 days), and determined the consequences of 5-ht depletion on stress-induced alterations of animal behaviors, hippocampal corticosteroid receptor immunoreactivity and the brain-derived neurotrophic factor (bdnf) mrna expression. |
2009-01-12 |
2023-08-12 |
rat |
| Jiansong Zhou, Lingjiang Li, Shaojun Tang, Xia Cao, Zexuan Li, Weihui Li, Changqi Li, Xianghui Zhan. Effects of serotonin depletion on the hippocampal GR/MR and BDNF expression during the stress adaptation. Behavioural brain research. vol 195. issue 1. 2009-01-12. PMID:18601957. |
these results suggest that hippocampal 5-ht depletion compromised adaptation to chronic stress. |
2009-01-12 |
2023-08-12 |
rat |
| Jiansong Zhou, Lingjiang Li, Shaojun Tang, Xia Cao, Zexuan Li, Weihui Li, Changqi Li, Xianghui Zhan. Effects of serotonin depletion on the hippocampal GR/MR and BDNF expression during the stress adaptation. Behavioural brain research. vol 195. issue 1. 2009-01-12. PMID:18601957. |
the study suggest that 5-ht deficiency in the adult hippocampus may impair stress adaptation by suppressing hippocampal gr and bdnf expression. |
2009-01-12 |
2023-08-12 |
rat |
| Aleksandra Wisłowska-Stanek, Adam Hamed, Małgorzata Lehner, Andrzej Bidziński, Danuta Turzyńska, Alicja Sobolewska, Jerzy Walkowiak, Adam Płaźni. Effects of midazolam and buspirone on in vivo concentration of amino acids and monoamine metabolites in the rat hippocampus. Pharmacological reports : PR. vol 60. issue 2. 2009-01-09. PMID:18443382. |
the effects of anxiolytic doses of buspirone and midazolam (established in the conditioned fear test) on extracellular concentrations of glutamate, gaba, serotonin and dopamine metabolites in the hippocampus were examined in vivo, in freely moving rats. |
2009-01-09 |
2023-08-12 |
rat |
| Aleksandra Wisłowska-Stanek, Adam Hamed, Małgorzata Lehner, Andrzej Bidziński, Danuta Turzyńska, Alicja Sobolewska, Jerzy Walkowiak, Adam Płaźni. Effects of midazolam and buspirone on in vivo concentration of amino acids and monoamine metabolites in the rat hippocampus. Pharmacological reports : PR. vol 60. issue 2. 2009-01-09. PMID:18443382. |
the present results provide more arguments for the role of hippocampal 5-ht in the effects of anxiolytic drugs. |
2009-01-09 |
2023-08-12 |
rat |
| I G Sil'ki. [Paradoxical sleep as a tool for understanding hippocampal mechanisms of contextual memory]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 58. issue 5. 2009-01-08. PMID:19004313. |
existing data on hippocampal involvement in contextual memory and the fact that contextual memory is deranged during rem sleep dreams allowed us to assume that one of the reasons for this derangement could be a change in the efficacy of synaptic transmission in the hippocampus because of a rise (as compared to wakefulness) of acetylcholine, cortisol, and dopamine concentrations and lack of serotonin and norepinephrine. |
2009-01-08 |
2023-08-12 |
Not clear |
| Leonardo Restivo, François Roman, Aline Dumuis, Joel Bockaert, Evelyne Marchetti, Martine Ammassari-Teul. The promnesic effect of G-protein-coupled 5-HT4 receptors activation is mediated by a potentiation of learning-induced spine growth in the mouse hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 10. 2008-12-22. PMID:18075492. |
here, we report that pretraining administration of the serotonin 5-ht(4) receptors (5-ht(4)rs) partial agonist sl65.0155 enhances simultaneous olfactory discrimination performance and potentiates learning-induced dendritic spine growth in the mouse hippocampus. |
2008-12-22 |
2023-08-12 |
mouse |
| Leonardo Restivo, François Roman, Aline Dumuis, Joel Bockaert, Evelyne Marchetti, Martine Ammassari-Teul. The promnesic effect of G-protein-coupled 5-HT4 receptors activation is mediated by a potentiation of learning-induced spine growth in the mouse hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 10. 2008-12-22. PMID:18075492. |
these findings provide evidence that 5-ht(4)rs stimulation selectively increases experience-dependent structural plasticity in learning-activated hippocampal circuits. |
2008-12-22 |
2023-08-12 |
mouse |
| A Lothe, A Didelot, A Hammers, N Costes, M Saoud, F Gilliam, P Ryvli. Comorbidity between temporal lobe epilepsy and depression: a [18F]MPPF PET study. Brain : a journal of neurology. vol 131. issue Pt 10. 2008-12-22. PMID:18765418. |
we used a distinct 5-ht(1a) antagonist, [(18)f]mppf, whose binding potential depends on both receptor density and extracellular serotonin concentration, in 24 patients with drug-resistant tle and mri evidence of hippocampal sclerosis but without prior antidepressant exposure. |
2008-12-22 |
2023-08-12 |
Not clear |
| Qiang M. Beneficial effects of moderate voluntary physical exercise and its biological mechanisms on brain health. Neuroscience bulletin. vol 24. issue 4. 2008-12-19. PMID:18668156. |
the up-active pathway is associated with enhancements of several neurotransmitters systems afferent to hippocampus, including norepinephrine (ne), serotonin (5-hydroxytryptamine, 5-ht), acetylcholine (ach) and gamma-aminobutyric acid (gaba). |
2008-12-19 |
2023-08-12 |
Not clear |
| Céline Riegert, Franziska Wedekind, Sami Ben Hamida, Susanne Rutz, Anna Katharina Rothmaier, Byron C Jones, Jean-Christophe Cassel, Rolf Jackisc. Effects of ethanol and 3,4-methylenedioxymethamphetamine (MDMA) alone or in combination on spontaneous and evoked overflow of dopamine, serotonin and acetylcholine in striatal slices of the rat brain. The international journal of neuropsychopharmacology. vol 11. issue 6. 2008-12-18. PMID:18248690. |
using a slice superfusion approach, we assessed the effects of mdma (0.3, 3microm) and/or etoh (2mm) on the spontaneous outflow and electrically evoked release of serotonin (5-ht), dopamine (da) and acetylcholine (ach) in the striatum, and for comparison, on 5-ht release in hippocampal and neocortical tissue. |
2008-12-18 |
2023-08-12 |
rat |
| Eszter Kirilly, Eszter Molnar, Brigitta Balogh, Sandor Kantor, Stefan R Hansson, Miklos Palkovits, Gyorgy Bagd. Decrease in REM latency and changes in sleep quality parallel serotonergic damage and recovery after MDMA: a longitudinal study over 180 days. The international journal of neuropsychopharmacology. vol 11. issue 6. 2008-12-18. PMID:18261250. |
at 7 d and 21 d after mdma treatment, significant(30-40%), widespread reductions in serotonin transporter (5-htt) density were detected in the cerebral cortex, hippocampus, most parts of the hypothalamus, and some of the brainstem nuclei. |
2008-12-18 |
2023-08-12 |
human |
| Soledad Sánchez, Cristina Sánchez, Sergio D Paredes, Javier Cubero, Ana B Rodríguez, Carmen Barrig. Circadian variations of serotonin in plasma and different brain regions of rats. Molecular and cellular biochemistry. vol 317. issue 1-2. 2008-12-16. PMID:18563534. |
ours results show that the maximum levels of serotonin in plasma were obtained at 09:00 and 22:00 and a minor peak at 01:00 h. in hypothalamus there was a significant peak at 22:00 and two minor peaks at 17:00 and 02:00 h; the same occurred in hippocampus with a significant peak at 21:00, and two secondary peaks at 24:00 and 05:00 h; in cerebellum there were two peaks at 21:00 and 02:00 h, while in striatum and pineal there were peaks at 21:00 h and 23:00, respectively. |
2008-12-16 |
2023-08-12 |
rat |
| Olaf Schulte-Herbrüggen, Heide Hörtnagl, Gerald Ponath, Matthias Rothermundt, Rainer Hellwe. Distinct regulation of brain-derived neurotrophic factor and noradrenaline in S100B knockout mice. Neuroscience letters. vol 442. issue 2. 2008-12-12. PMID:18638525. |
therefore we investigated levels of serotonin (5-ht) and its metabolite 5-hydroxyindoleacetic acid (5-hiaa), noradrenaline (na), dopamine (da), brain-derived neurotrophic factor (bdnf) and nerve growth factor (ngf) in the hippocampus, frontal cortex and residual neocortex in s100b knock out (s100b ko) mice compared to wildtype controls. |
2008-12-12 |
2023-08-12 |
mouse |
| Barbara E H Sumner, Richard B D'Eath, Mark J Farnworth, Sheena Robson, John A Russell, Alistair B Lawrence, Susan Jarvi. Early weaning results in less active behaviour, accompanied by lower 5-HT1A and higher 5-HT2A receptor mRNA expression in specific brain regions of female pigs. Psychoneuroendocrinology. vol 33. issue 8. 2008-12-09. PMID:18653286. |
in d12 pigs, 5-ht(1a) receptor mrna expression per unit area was 29%, 63%, 52% and 64% lower than in d42 pigs in the parvocellular pvn, amygdala and hippocampal dentate gyrus and pyramidal cell layer, respectively. |
2008-12-09 |
2023-08-12 |
Not clear |
| J H Sliwowska, N Lan, F Yamashita, A G Halpert, V Viau, J Weinber. Effects of prenatal ethanol exposure on regulation of basal hypothalamic-pituitary-adrenal activity and hippocampal 5-HT1A receptor mRNA levels in female rats across the estrous cycle. Psychoneuroendocrinology. vol 33. issue 8. 2008-12-09. PMID:18672336. |
we demonstrate, for the first time, long-lasting consequences of prenatal ethanol exposure for basal corticosterone (cort) regulation and basal levels of hippocampal mineralocorticoid (mr), glucocorticoid (gr) and serotonin type 1a (5-ht(1a)) receptor mrna, as a function of estrous cycle stage: (1) basal cort levels were higher in e compared to c females in proestrus but lower in e and pf compared to c females in estrus; (2) there were no differences among groups in basal levels of adrenocorticotropin (acth), estradiol or progesterone; (3) hippocampal mr mrna levels were decreased in e compared to pf and c females across the estrus cycle, with the greatest effects in proestrus, whereas e (but not pf or c) females had higher hippocampal gr mrna levels in proestrus than in estrous and diestrus; (4) 5-ht(1a) mrna levels were increased in e compared to pf and c females in diestrus. |
2008-12-09 |
2023-08-12 |
rat |
| Benicio N Frey, Pedro Rosa-Neto, Stuart Lubarsky, Mirko Diksi. Correlation between serotonin synthesis and 5-HT1A receptor binding in the living human brain: a combined alpha-[11C]MT and [18F]MPPF positron emission tomography study. NeuroImage. vol 42. issue 2. 2008-12-08. PMID:18583156. |
a significant negative correlation between serotonin synthesis and 5-ht(1a) binding potential was found bilaterally in hippocampus and anterior insula and in the left acc. |
2008-12-08 |
2023-08-12 |
human |
| Tadimeti S Rao, Pamala B Adams, Lucia D Correa, Emily M Santori, Aida I Sacaan, Richard T Reid, Nicholas D P Cosfor. Pharmacological characterization of (S)-(2)-5-ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine HCl (SIB-1508Y, Altinicline), a novel nicotinic acetylcholine receptor agonist. Brain research. vol 1234. 2008-12-08. PMID:18692487. |
relative to its robust effects on da release from various brain regions, sib-1508y was minimally effective at increasing ne release from hippocampus or pfc, and 5-ht release from pfc. |
2008-12-08 |
2023-08-12 |
rat |