| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qun Xu, Ying Pan, Li-Tao Yi, Yu-Cheng Li, Shi-Fu Mo, Fu-Xin Jiang, Chun-Feng Qiao, Hong-Xi Xu, Xiao-Bo Lu, Ling-Dong Kong, Hsiang-Fu Kun. Antidepressant-like effects of psoralen isolated from the seeds of Psoralea corylifolia in the mouse forced swimming test. Biological & pharmaceutical bulletin. vol 31. issue 6. 2008-06-30. PMID:18520040. |
psoralen remarkably reversed fst-induced alterations in serotonin (5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) levels in frontal cortex and hippocampus in mice. |
2008-06-30 |
2023-08-12 |
mouse |
| L Truchot, N Costes, L Zimmer, B Laurent, D Le Bars, C Thomas-Antérion, B Mercier, M Hermier, A Vighetto, P Krolak-Salmo. A distinct [18F]MPPF PET profile in amnestic mild cognitive impairment compared to mild Alzheimer's disease. NeuroImage. vol 40. issue 3. 2008-06-17. PMID:18313943. |
to date, two positron emission tomography (pet) studies have explored 5-ht(1a) receptor density in the hippocampus of alzheimer's disease (ad) patients. |
2008-06-17 |
2023-08-12 |
Not clear |
| F J van der Staay, J de Groot, T Schuurman, S M Kort. Repeated social defeat in female pigs does not induce neuroendocrine symptoms of depression, but behavioral adaptation. Physiology & behavior. vol 93. issue 3. 2008-06-12. PMID:17991496. |
serotonin turnover in the dorsal hippocampus was also unaffected. |
2008-06-12 |
2023-08-12 |
Not clear |
| B Marcos, B Aisa, M J Ramíre. Functional interaction between 5-HT(6) receptors and hypothalamic-pituitary-adrenal axis: cognitive implications. Neuropharmacology. vol 54. issue 4. 2008-06-12. PMID:18206183. |
in a situation of increased hpa axis responsiveness (maternal separation, ms) no differences were found in the expression of 5-ht(6) gene in the hippocampus or frontal cortex, although serotonin levels were higher in the frontal cortex of ms rats. |
2008-06-12 |
2023-08-12 |
rat |
| B Marcos, B Aisa, M J Ramíre. Functional interaction between 5-HT(6) receptors and hypothalamic-pituitary-adrenal axis: cognitive implications. Neuropharmacology. vol 54. issue 4. 2008-06-12. PMID:18206183. |
5-ht(6) receptor mrna expression increased significantly in the hippocampus in a situation of decreased glucocorticoid levels, such as adrenalectomy. |
2008-06-12 |
2023-08-12 |
rat |
| Devon L Graham, Pierre-A H Noailles, Jean Lud Cade. Differential neurochemical consequences of an escalating dose-binge regimen followed by single-day multiple-dose methamphetamine challenges. Journal of neurochemistry. vol 105. issue 5. 2008-06-12. PMID:18248616. |
both challenge doses of meth caused significant degrees of depletion of dopamine in the striatum and norepinephrine and serotonin in the striatum, cortex, and hippocampus. |
2008-06-12 |
2023-08-12 |
human |
| Fumihiro Shutoh, Ayuka Ina, Sachine Yoshida, Jinko Konno, Setsuji Hisan. Two distinct subtypes of serotonergic fibers classified by co-expression with vesicular glutamate transporter 3 in rat forebrain. Neuroscience letters. vol 432. issue 2. 2008-06-02. PMID:18222609. |
although virtually all of serotonin (5-ht) neurons in the midbrain raphe nuclei of rats are known to express vesicular glutamate transporter 3 (vglut3), vglut3-positive 5-ht fibers have been identified only in the cerebral cortex and hippocampus. |
2008-06-02 |
2023-08-12 |
rat |
| Tanel Mällo, Kadri Kõiv, Indrek Koppel, Karita Raudkivi, Ain Uustare, Ago Rinken, Tõnis Timmusk, Jaanus Harr. Regulation of extracellular serotonin levels and brain-derived neurotrophic factor in rats with high and low exploratory activity. Brain research. vol 1194. 2008-05-30. PMID:18177844. |
no difference in 5-htt levels was found in hippocampus, while perfusion with citalopram was accompanied by a greater increase in extracellular 5-ht in the he group in this brain region. |
2008-05-30 |
2023-08-12 |
rat |
| Gunnar Thiemann, Vincenzo Di Marzo, Areles Molleman, Rüdiger U Hasenöhr. The CB(1) cannabinoid receptor antagonist AM251 attenuates amphetamine-induced behavioural sensitization while causing monoamine changes in nucleus accumbens and hippocampus. Pharmacology, biochemistry, and behavior. vol 89. issue 3. 2008-05-20. PMID:18294680. |
furthermore, the behavioural effects of am251 were paralleled by increased dopamine concentration in nucleus accumbens and increased serotonin concentration/turnover rate in hippocampus, respectively. |
2008-05-20 |
2023-08-12 |
mouse |
| Gunnar Thiemann, Vincenzo Di Marzo, Areles Molleman, Rüdiger U Hasenöhr. The CB(1) cannabinoid receptor antagonist AM251 attenuates amphetamine-induced behavioural sensitization while causing monoamine changes in nucleus accumbens and hippocampus. Pharmacology, biochemistry, and behavior. vol 89. issue 3. 2008-05-20. PMID:18294680. |
the present data indicate that under normal conditions activation of the cb(1) receptor facilitates those adaptive responses elicited by repeated psychostimulant administration and resulting in sensitization, possibly by reducing dopamine biosynthesis and serotonin turnover in the nucleus accumbens and hippocampus. |
2008-05-20 |
2023-08-12 |
mouse |
| Astrid C E Linthorst, Cornelia Flachskamm, Johannes M H M Reu. Water temperature determines neurochemical and behavioural responses to forced swim stress: an in vivo microdialysis and biotelemetry study in rats. Stress (Amsterdam, Netherlands). vol 11. issue 2. 2008-05-16. PMID:17853068. |
a rapid and pronounced increase in hippocampal 5-ht and 5-hiaa was found in rats that swam at 35 degrees c, whereas biphasic responses in 5-ht and 5-hiaa were observed at 25 and 19 degrees c. also swim stress behaviour and post-stress home cage behaviour depended on the water temperature. |
2008-05-16 |
2023-08-12 |
rat |
| Astrid C E Linthorst, Cornelia Flachskamm, Johannes M H M Reu. Water temperature determines neurochemical and behavioural responses to forced swim stress: an in vivo microdialysis and biotelemetry study in rats. Stress (Amsterdam, Netherlands). vol 11. issue 2. 2008-05-16. PMID:17853068. |
swimming-induced increases in hippocampal extracellular concentrations of 5-ht and 5-hiaa occurred at all water temperatures, but these increases were temporarily quenched, or concentrations were transistently decreased, when core body temperature fell below 31 degrees c in water at 25 or 19 degrees c. these data demonstrate that water temperature is a key factor determining the impact of forced swim stress on behaviour and neurochemistry, and underscore that changes in these parameters should be interpreted in the light of the autonomic responses induced by this stressor. |
2008-05-16 |
2023-08-12 |
rat |
| Hideki Miura, Norio Ozaki, Tetsuya Shirokawa, Kenichi Isob. Changes in brain tryptophan metabolism elicited by ageing, social environment, and psychological stress in mice. Stress (Amsterdam, Netherlands). vol 11. issue 2. 2008-05-16. PMID:18311604. |
we measured trp, kyn and 5-ht contents in the prefrontal cortex, hippocampus, amygdala and dorsal raphe nuclei to investigate the balance between the kyn and 5-ht pathways. |
2008-05-16 |
2023-08-12 |
mouse |
| Gordon Munro, Camilla A E Baek, Helle K Erichsen, Alexander N Nielsen, Elsebet Ø Nielsen, Jørgen Scheel-Kruger, Pia Weikop, Dan Peter. The novel compound (+/-)-1-[10-((E)-3-Phenyl-allyl)-3,10-diaza-bicyclo[4.3.1]dec-3-yl]-propan-1-one (NS7051) attenuates nociceptive transmission in animal models of experimental pain; a pharmacological comparison with the combined mu-opioid receptor agonist and monoamine reuptake inhibitor tramadol. Neuropharmacology. vol 54. issue 2. 2008-05-12. PMID:18037451. |
here, we present data for the novel compound ns7051, which was shown to have sub-micromolar affinity (ki=0.034microm) for micro-opioid receptors and inhibited reuptake of 5-ht, na and da (ic(50)=4.2, 3.3 and 3.5microm in cortex, hippocampus and striatum respectively). |
2008-05-12 |
2023-08-12 |
rat |
| Megan E Kozisek, David Middlemas, David B Bylun. The differential regulation of BDNF and TrkB levels in juvenile rats after four days of escitalopram and desipramine treatment. Neuropharmacology. vol 54. issue 2. 2008-05-12. PMID:18048068. |
in the present study we report parallel measurements of bdnf mrna and protein in the frontal cortex and hippocampus after four days of twice daily treatments with escitalopram, a selective serotonin reuptake inhibitor, and desipramine, a tricyclic antidepressant. |
2008-05-12 |
2023-08-12 |
rat |
| Tamás Balázsa, Judit Bíró, Nóra Gullai, Catherine Ledent, Beáta Sperlág. CB1-cannabinoid receptors are involved in the modulation of non-synaptic [3H]serotonin release from the rat hippocampus. Neurochemistry international. vol 52. issue 1-2. 2008-05-05. PMID:17719142. |
cb1-cannabinoid receptors are involved in the modulation of non-synaptic [3h]serotonin release from the rat hippocampus. |
2008-05-05 |
2023-08-12 |
mouse |
| Tamás Balázsa, Judit Bíró, Nóra Gullai, Catherine Ledent, Beáta Sperlág. CB1-cannabinoid receptors are involved in the modulation of non-synaptic [3H]serotonin release from the rat hippocampus. Neurochemistry international. vol 52. issue 1-2. 2008-05-05. PMID:17719142. |
in the present study we investigated whether serotonin release in the hippocampus is subject to regulation via cannabinoid receptors. |
2008-05-05 |
2023-08-12 |
mouse |
| Tamás Balázsa, Judit Bíró, Nóra Gullai, Catherine Ledent, Beáta Sperlág. CB1-cannabinoid receptors are involved in the modulation of non-synaptic [3H]serotonin release from the rat hippocampus. Neurochemistry international. vol 52. issue 1-2. 2008-05-05. PMID:17719142. |
both rat and mouse hippocampal slices were preincubated with [3h]serotonin ([3h]5-ht) and superfused with medium containing serotonin reuptake inhibitor citalopram hydrobromide (300 nm). |
2008-05-05 |
2023-08-12 |
mouse |
| R Christensen, A B Marcussen, G Wörtwein, G M Knudsen, S Azna. Abeta(1-42) injection causes memory impairment, lowered cortical and serum BDNF levels, and decreased hippocampal 5-HT(2A) levels. Experimental neurology. vol 210. issue 1. 2008-05-02. PMID:18053988. |
abeta(1-42) injection causes memory impairment, lowered cortical and serum bdnf levels, and decreased hippocampal 5-ht(2a) levels. |
2008-05-02 |
2023-08-12 |
rat |
| R Christensen, A B Marcussen, G Wörtwein, G M Knudsen, S Azna. Abeta(1-42) injection causes memory impairment, lowered cortical and serum BDNF levels, and decreased hippocampal 5-HT(2A) levels. Experimental neurology. vol 210. issue 1. 2008-05-02. PMID:18053988. |
in the abeta(1-42) injected animals we saw an abolished increase in serum bdnf levels that was accompanied by significant lower bdnf levels in frontal cortex and by an 8.5% reduction in hippocampal 5-ht(2a) receptor levels. |
2008-05-02 |
2023-08-12 |
rat |