| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kaneez Fatima Shad, Sheik Arshad Saee. The metabolism of serotonin in neuronal cells in culture and platelets. Experimental brain research. vol 183. issue 3. 2008-04-04. PMID:17912506. |
the aim of this study is to find a relationship between serotonin (5-ht) and its metabolite 5-hydroxy indol acetic acid (5-hiaa) in hippocampus, frontal neocortex and platelets. |
2008-04-04 |
2023-08-12 |
human |
| Kaneez Fatima Shad, Sheik Arshad Saee. The metabolism of serotonin in neuronal cells in culture and platelets. Experimental brain research. vol 183. issue 3. 2008-04-04. PMID:17912506. |
in human platelets, this ratio was 1.35 suggesting that the highest serotonin metabolism occurs in the frontal neocortex followed by the hippocampus and platelets. |
2008-04-04 |
2023-08-12 |
human |
| J Compton, M J Travis, R Norbury, K Erlandsson, T van Amelsvoort, E Daly, W Waddington, P Matthiasson, J L H Eersels, M Whitehead, R W Kerwin, P J Ell, D G M Murph. Long-term estrogen therapy and 5-HT(2A) receptor binding in postmenopausal women; a single photon emission tomography (SPET) study. Hormones and behavior. vol 53. issue 1. 2008-04-03. PMID:17956758. |
never-users had significantly higher 5-ht(2a) receptor availability than estrogen-users in hippocampus (1.17 vs. 1.11, respectively, p=0.02), although this did not remain significant after correction for multiple comparisons. |
2008-04-03 |
2023-08-12 |
human |
| J Compton, M J Travis, R Norbury, K Erlandsson, T van Amelsvoort, E Daly, W Waddington, P Matthiasson, J L H Eersels, M Whitehead, R W Kerwin, P J Ell, D G M Murph. Long-term estrogen therapy and 5-HT(2A) receptor binding in postmenopausal women; a single photon emission tomography (SPET) study. Hormones and behavior. vol 53. issue 1. 2008-04-03. PMID:17956758. |
hippocampal 5-ht(2a) receptor availability correlated negatively with verbal and general memory and delayed recall (r=-0.45, p=0.01; r=-0.40, p=0.02; r=-0.36, p=0.04). |
2008-04-03 |
2023-08-12 |
human |
| J Compton, M J Travis, R Norbury, K Erlandsson, T van Amelsvoort, E Daly, W Waddington, P Matthiasson, J L H Eersels, M Whitehead, R W Kerwin, P J Ell, D G M Murph. Long-term estrogen therapy and 5-HT(2A) receptor binding in postmenopausal women; a single photon emission tomography (SPET) study. Hormones and behavior. vol 53. issue 1. 2008-04-03. PMID:17956758. |
long-term et may be associated with lower 5-ht(2a) receptor availability in hippocampus. |
2008-04-03 |
2023-08-12 |
human |
| J Compton, M J Travis, R Norbury, K Erlandsson, T van Amelsvoort, E Daly, W Waddington, P Matthiasson, J L H Eersels, M Whitehead, R W Kerwin, P J Ell, D G M Murph. Long-term estrogen therapy and 5-HT(2A) receptor binding in postmenopausal women; a single photon emission tomography (SPET) study. Hormones and behavior. vol 53. issue 1. 2008-04-03. PMID:17956758. |
also, increased availability of the 5-ht(2a) receptor in hippocampus is associated with poorer memory function. |
2008-04-03 |
2023-08-12 |
human |
| M El Mansari, P Blie. In vivo electrophysiological assessment of the putative antidepressant Wf-516 in the rat raphe dorsalis, locus coeruleus and hippocampus. Naunyn-Schmiedeberg's archives of pharmacology. vol 376. issue 5. 2008-04-03. PMID:18060386. |
in the hippocampus, cumulative intravenous doses of wf-516 significantly increased the recovery time of firing activity of ca(3) pyramidal neurons after 5-ht applications, indicating an inhibitory effect on 5-ht reuptake. |
2008-04-03 |
2023-08-12 |
rat |
| Tori L Schaefer, Matthew R Skelton, Nicole R Herring, Gary A Gudelsky, Charles V Vorhees, Michael T William. Short- and long-term effects of (+)-methamphetamine and (+/-)-3,4-methylenedioxymethamphetamine on monoamine and corticosterone levels in the neonatal rat following multiple days of treatment. Journal of neurochemistry. vol 104. issue 6. 2008-03-26. PMID:17996031. |
both drugs decreased hippocampal 5-ht on p16 and p21, although mdma produced larger reductions. |
2008-03-26 |
2023-08-12 |
rat |
| Hristina Jovanovic, Johan Lundberg, Per Karlsson, Asta Cerin, Tomoyuki Saijo, Andrea Varrone, Christer Halldin, Anna-Lena Nordströ. Sex differences in the serotonin 1A receptor and serotonin transporter binding in the human brain measured by PET. NeuroImage. vol 39. issue 3. 2008-03-25. PMID:18036835. |
in women, there was a positive correlation between 5-ht(1a) receptor and 5-htt binding potentials for the region of hippocampus. |
2008-03-25 |
2023-08-12 |
human |
| Seth D Norrholm, David B Horton, Linda P Dwoski. The promiscuity of the dopamine transporter: implications for the kinetic analysis of [3H]serotonin uptake in rat hippocampal and striatal synaptosomes. Neuropharmacology. vol 53. issue 8. 2008-03-21. PMID:18022203. |
the promiscuity of the dopamine transporter: implications for the kinetic analysis of [3h]serotonin uptake in rat hippocampal and striatal synaptosomes. |
2008-03-21 |
2023-08-12 |
rat |
| Seth D Norrholm, David B Horton, Linda P Dwoski. The promiscuity of the dopamine transporter: implications for the kinetic analysis of [3H]serotonin uptake in rat hippocampal and striatal synaptosomes. Neuropharmacology. vol 53. issue 8. 2008-03-21. PMID:18022203. |
we performed a kinetic analysis of [(3)h]serotonin uptake in rat striatal synaptosomes (expressing dat and sert) and hippocampal synaptosomes (expressing sert, but not dat). |
2008-03-21 |
2023-08-12 |
rat |
| Seth D Norrholm, David B Horton, Linda P Dwoski. The promiscuity of the dopamine transporter: implications for the kinetic analysis of [3H]serotonin uptake in rat hippocampal and striatal synaptosomes. Neuropharmacology. vol 53. issue 8. 2008-03-21. PMID:18022203. |
in hippocampal synaptosomes, k(m) and v(max) values for [(3)h]serotonin uptake did not differ whether fluoxetine or paroxetine was used to define nonspecific uptake. |
2008-03-21 |
2023-08-12 |
rat |
| Seth D Norrholm, David B Horton, Linda P Dwoski. The promiscuity of the dopamine transporter: implications for the kinetic analysis of [3H]serotonin uptake in rat hippocampal and striatal synaptosomes. Neuropharmacology. vol 53. issue 8. 2008-03-21. PMID:18022203. |
thus, when dat is inhibited by gbr 12909, kinetic parameters for serotonin uptake via sert in striatum are not different from those obtained in hippocampus. |
2008-03-21 |
2023-08-12 |
rat |
| W Otten, E Kanitz, M Tuchscherer, K-P Brüssow, G Nürnber. Repeated administrations of adrenocorticotropic hormone during late gestation in pigs: maternal cortisol response and effects on fetal HPA axis and brain neurotransmitter systems. Theriogenology. vol 69. issue 3. 2008-03-20. PMID:17983648. |
however, in hippocampus, serotonergic activity was increased in fetuses from acth-treated mothers as shown by significantly elevated 5-hydroxytryptamine (5-ht) levels. |
2008-03-20 |
2023-08-12 |
Not clear |
| Michelle Roche, Emer O'Connor, Catherine Diskin, David P Fin. The effect of CB(1) receptor antagonism in the right basolateral amygdala on conditioned fear and associated analgesia in rats. The European journal of neuroscience. vol 26. issue 9. 2008-03-14. PMID:17970731. |
sr141716a-induced analgesia was accompanied by reduced da, increased hva : da ratio and reduced 5-ht levels in the cerebellum, increased hippocampal hva levels and increased 5-hydroxyindole-3-acetic acid (5-hiaa) in the amygdaloid cortex. |
2008-03-14 |
2023-08-12 |
rat |
| Vanessa Nunes-de-Souza, Ricardo Luiz Nunes-de-Souza, Robert John Rodgers, Azair Canto-de-Souz. 5-HT2 receptor activation in the midbrain periaqueductal grey (PAG) reduces anxiety-like behaviour in mice. Behavioural brain research. vol 187. issue 1. 2008-03-11. PMID:17935799. |
thus, whereas stimulation of 5-ht 1a or 5-ht2 receptors in the limbic forebrain (amygdala, hippocampus) enhances anxiety-like responding in rodents, activation of corresponding receptor populations in the midbrain periaqueductal grey (pag) more often than not reduce anxiety-like behaviour. |
2008-03-11 |
2023-08-12 |
mouse |
| Klaus B Fink, Manfred Göther. 5-HT receptor regulation of neurotransmitter release. Pharmacological reviews. vol 59. issue 4. 2008-03-06. PMID:18160701. |
5-ht(1b) receptors on neocortical cholinergic, striatal dopaminergic, or hippocampal gabaergic axon terminals are examples for release-inhibiting 5-ht heteroreceptors; 5-ht(3) receptors on hippocampal gabaergic or 5-ht(4) receptors on hippocampal cholinergic axon terminals are examples for release-facilitating 5-ht heteroreceptors. |
2008-03-06 |
2023-08-12 |
Not clear |
| Klaus B Fink, Manfred Göther. 5-HT receptor regulation of neurotransmitter release. Pharmacological reviews. vol 59. issue 4. 2008-03-06. PMID:18160701. |
conversely, attenuated gaba release in response to activation of inhibitory 5-ht heteroreceptors, e.g., 5-ht(1a) or 5-ht(1b) receptors on gabaergic interneurons is involved in paradoxical facilitation of hippocampal acetylcholine and striatal dopamine release, respectively. |
2008-03-06 |
2023-08-12 |
Not clear |
| b' Astrid Bj\\xc3\\xb8rnebekk, Aleksander A Math\\xc3\\xa9, Susanne H M Gruber, Stefan Bren\\xc3\\xa. Social isolation increases number of newly proliferated cells in hippocampus in female flinders sensitive line rats. Hippocampus. vol 17. issue 12. 2008-02-29. PMID:17879375.' |
in an animal model of depression, flinders sensitive line rats, and sprague dawley controls we analyzed if 7 weeks of social isolation of adult animals affect the number of newly proliferated cells in the dentate gyrus or mrnas of neuropeptide y (npy), the npy-y1 receptor, nociceptin, bdnf, and the serotonin 5ht1a and 5ht2a receptors, which are molecules involved in hippocampal plasticity. |
2008-02-29 |
2023-08-12 |
rat |
| Maurizio Severino, Anja F Pedersen, Viktorija Trajkovska, Ellen Christensen, Rasmus Lohals, Lone M Veng, Gitte M Knudsen, Susana Azna. Selective immunolesion of cholinergic neurons leads to long-term changes in 5-HT2A receptor levels in hippocampus and frontal cortex. Neuroscience letters. vol 428. issue 1. 2008-02-25. PMID:17945418. |
5-ht(2a) protein levels were determined by western techniques in frontal cortex and hippocampus. |
2008-02-25 |
2023-08-12 |
rat |