| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Arash Mowla, Masoud Mosavinasab, Hasan Haghshenas, Afshin Borhani Haghigh. Does serotonin augmentation have any effect on cognition and activities of daily living in Alzheimer's dementia? A double-blind, placebo-controlled clinical trial. Journal of clinical psychopharmacology. vol 27. issue 5. 2008-01-02. PMID:17873681. |
in several studies, selective serotonin reuptake inhibitors demonstrated promotion in neurogenesis in the hippocampus and enhanced memory and cognition. |
2008-01-02 |
2023-08-12 |
Not clear |
| Gino Giannaccini, Laura Betti, Andrea Pirone, Lionella Palego, Ortenzio Fabiani, Laura Fabbrini, Giovanni Mascia, Laura Giusti, Marco Macchia, Mario Giusiani, Claudia Martini, Antonio Lucacchin. Short-term effects of 3,4-methylen-dioxy-metamphetamine (MDMA) on 5-HT(1A) receptors in the rat hippocampus. Neurochemistry international. vol 51. issue 8. 2007-12-21. PMID:17602794. |
short-term effects of 3,4-methylen-dioxy-metamphetamine (mdma) on 5-ht(1a) receptors in the rat hippocampus. |
2007-12-21 |
2023-08-12 |
rat |
| Gino Giannaccini, Laura Betti, Andrea Pirone, Lionella Palego, Ortenzio Fabiani, Laura Fabbrini, Giovanni Mascia, Laura Giusti, Marco Macchia, Mario Giusiani, Claudia Martini, Antonio Lucacchin. Short-term effects of 3,4-methylen-dioxy-metamphetamine (MDMA) on 5-HT(1A) receptors in the rat hippocampus. Neurochemistry international. vol 51. issue 8. 2007-12-21. PMID:17602794. |
the first effects of 3,4-methylen-dioxy-metamphetamine (mdma, "ecstasy"), on serotonin 1a (5-ht(1a)) receptors in rat hippocampus were determined by means of [(3)h]-8-hydroxy-dipropylamino-tetralin ([(3)h]-8-oh-dpat) and 5'guanosine-(gamma-[(35)s]-thio)triphosphate ([(35)s]-gtpgammas) binding as well as inhibition of forskolin (fk)-stimulated adenylyl cyclase (ac) activity. |
2007-12-21 |
2023-08-12 |
rat |
| E Calcagno, A Canetta, S Guzzetti, L Cervo, R W Invernizz. Strain differences in basal and post-citalopram extracellular 5-HT in the mouse medial prefrontal cortex and dorsal hippocampus: relation with tryptophan hydroxylase-2 activity. Journal of neurochemistry. vol 103. issue 3. 2007-12-21. PMID:17666043. |
strain differences in basal and post-citalopram extracellular 5-ht in the mouse medial prefrontal cortex and dorsal hippocampus: relation with tryptophan hydroxylase-2 activity. |
2007-12-21 |
2023-08-12 |
mouse |
| E Calcagno, A Canetta, S Guzzetti, L Cervo, R W Invernizz. Strain differences in basal and post-citalopram extracellular 5-HT in the mouse medial prefrontal cortex and dorsal hippocampus: relation with tryptophan hydroxylase-2 activity. Journal of neurochemistry. vol 103. issue 3. 2007-12-21. PMID:17666043. |
dba/2j, dba/2n and balb/c mice carrying the 1473g allele of tph-2 had less dialysate 5-ht in the medial prefrontal cortex and dorsal hippocampus (dh) (20-40% reduction) than c57bl/6j and c57bl/6n mice carrying the 1473c allele. |
2007-12-21 |
2023-08-12 |
mouse |
| E Calcagno, A Canetta, S Guzzetti, L Cervo, R W Invernizz. Strain differences in basal and post-citalopram extracellular 5-HT in the mouse medial prefrontal cortex and dorsal hippocampus: relation with tryptophan hydroxylase-2 activity. Journal of neurochemistry. vol 103. issue 3. 2007-12-21. PMID:17666043. |
a tryptophan (trp) load enhanced basal extracellular 5-ht in the medial prefrontal cortex of dba/2j mice but did not affect citalopram's ability to raise cortical and hippocampal extracellular 5-ht. |
2007-12-21 |
2023-08-12 |
mouse |
| Xu-Feng Huang, Yean Yeow Tan, Xin Huang, Qing Wan. Effect of chronic treatment with clozapine and haloperidol on 5-HT(2A and 2C) receptor mRNA expression in the rat brain. Neuroscience research. vol 59. issue 3. 2007-12-21. PMID:17868938. |
following 2 h of drug withdrawal, it showed that clozapine administration significantly decreased 5-ht(2a) receptor mrna, predominantly in the nucleus accumbens (65%), hippocampus (80%), lasteral septal nucleus (61%) and striatum (68%) compared to controls, whilst rebound increases were observed in most of these regions 48 h later. |
2007-12-21 |
2023-08-12 |
rat |
| Pia Weikop, Takashi Yoshitake, Jan Keh. Differential effects of adjunctive methylphenidate and citalopram on extracellular levels of serotonin, noradrenaline and dopamine in the rat brain. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 17. issue 10. 2007-12-06. PMID:17383162. |
in the present study, in vivo microdialysis was used to monitor the extracellular levels of serotonin, noradrenaline and dopamine in the prefrontal cortex, hippocampus, nucleus accumbens and striatum of the rat. |
2007-12-06 |
2023-08-12 |
rat |
| Pia Weikop, Takashi Yoshitake, Jan Keh. Differential effects of adjunctive methylphenidate and citalopram on extracellular levels of serotonin, noradrenaline and dopamine in the rat brain. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 17. issue 10. 2007-12-06. PMID:17383162. |
citalopram-induced increase in serotonin levels was strongly enhanced by adjunctive methylphenidate in the hippocampus, but attenuated in the cortex. |
2007-12-06 |
2023-08-12 |
rat |
| Sven Ove Ogren, Haleh Razani, Elin Elvander-Tottie, Jan Keh. The neuropeptide galanin as an in vivo modulator of brain 5-HT1A receptors: possible relevance for affective disorders. Physiology & behavior. vol 92. issue 1-2. 2007-12-06. PMID:17585970. |
in the rat, galanin-like immunoreactivity is expressed in a population of 5-hydroxytryptamine (5-ht, serotonin) neurons in the dorsal raphe with extensive projections to the forebrain areas, e.g., hippocampus. |
2007-12-06 |
2023-08-12 |
rat |
| Jan Thöne, Martin Wieman. Serotonin but not zonisamide inhibits theophylline-induced epileptiform activity in guinea pig hippocampal CA3 neurons. Epilepsy research. vol 76. issue 1. 2007-12-06. PMID:17628426. |
to test the putative serotonin (5-ht)-like effect of zonisamide (zns) we employed xanthine-induced epileptiform activity in the hippocampus slice preparation from guinea pigs. |
2007-12-06 |
2023-08-12 |
Not clear |
| Jan Thöne, Martin Wieman. Serotonin but not zonisamide inhibits theophylline-induced epileptiform activity in guinea pig hippocampal CA3 neurons. Epilepsy research. vol 76. issue 1. 2007-12-06. PMID:17628426. |
we conclude that 5-ht augmenting effects of zns are missing or are not sufficient to inhibit epileptiform activity in hippocampal slice preparations. |
2007-12-06 |
2023-08-12 |
Not clear |
| Takashi Yamada, Takehiko Terashima, Keiko Wada, Sakiko Ueda, Mitsuyo Ito, Tsutomu Okubo, Lekh Raj Juneja, Hidehiko Yokogosh. Theanine, r-glutamylethylamide, increases neurotransmission concentrations and neurotrophin mRNA levels in the brain during lactation. Life sciences. vol 81. issue 16. 2007-11-26. PMID:17904164. |
some neurotransmitters, including dopamine, serotonin, glycine and gaba concentration, increased in the infant brain and ngf mrna level increased in the cerebral cortex and hippocampus. |
2007-11-26 |
2023-08-12 |
rat |
| Saida Haider, Saima Khaliq, Darakhshan J Halee. Enhanced serotonergic neurotransmission in the hippocampus following tryptophan administration improves learning acquisition and memory consolidation in rats. Pharmacological reports : PR. vol 59. issue 1. 2007-11-20. PMID:17377206. |
in the present study, we examined the effects of increased hippocampal 5-ht metabolism following tryptophan (trp) administration on short-term memory (stm) and long-term memory (ltm) in rats. |
2007-11-20 |
2023-08-12 |
rat |
| Shaun Fallon, Erin Shearman, Henry Sershen, Abel Lajth. Food reward-induced neurotransmitter changes in cognitive brain regions. Neurochemical research. vol 32. issue 10. 2007-11-20. PMID:17721820. |
dopamine metabolites increased in all areas tested (except the dorsal hippocampus); changes in norepinephrine varied with decreases in the accumbens, dorsal hippocampus, amygdala, and thalamic nucleus, and increases in the prefrontal cortex; serotonin levels decreased in all the areas tested; although its metabolite 5hiaa increased in two regions (the medial temporal cortex, and thalamic nucleus). |
2007-11-20 |
2023-08-12 |
Not clear |
| Ouissame Mnie-Filali, Céline Faure, Mostafa El Mansari, Laura Lambás-Señas, Anne Bérod, Luc Zimmer, Connie Sánchez, Nasser Haddjer. R-citalopram prevents the neuronal adaptive changes induced by escitalopram. Neuroreport. vol 18. issue 15. 2007-11-20. PMID:17885600. |
this study examined the long-term effects of the antidepressant escitalopram on rat serotonin (5-ht) neuronal activity and hippocampal neuroplasticity. |
2007-11-20 |
2023-08-12 |
rat |
| Ouissame Mnie-Filali, Céline Faure, Mostafa El Mansari, Laura Lambás-Señas, Anne Bérod, Luc Zimmer, Connie Sánchez, Nasser Haddjer. R-citalopram prevents the neuronal adaptive changes induced by escitalopram. Neuroreport. vol 18. issue 15. 2007-11-20. PMID:17885600. |
the present results support the role of the allosteric modulation of the 5-ht transporter in the regulation of the recovery of 5-ht neuronal activity and long-lasting hippocampal cellular plasticity induced by escitalopram, two adaptive changes presumably associated with the antidepressant response. |
2007-11-20 |
2023-08-12 |
rat |
| Anna Pittaluga, Luca Raiteri, Fabio Longordo, Elisa Luccini, Valentina Sara Barbiero, Giorgio Racagni, Maurizio Popoli, Maurizio Raiter. Antidepressant treatments and function of glutamate ionotropic receptors mediating amine release in hippocampus. Neuropharmacology. vol 53. issue 1. 2007-11-09. PMID:17543354. |
isolated hippocampal nerve endings (synaptosomes) prepared following acute/chronic treatments were labelled with [(3)h]na or [(3)h]5-ht and [(3)h]amine release was monitored during exposure in superfusion to nmda/glycine, ampa or k(+)-depolarization. |
2007-11-09 |
2023-08-12 |
rat |
| T Bibancos, D L Jardim, I Aneas, S Chiavegatt. Social isolation and expression of serotonergic neurotransmission-related genes in several brain areas of male mice. Genes, brain, and behavior. vol 6. issue 6. 2007-11-06. PMID:17083332. |
in contrast, the only alteration in the hippocampus was 5-ht(6) overexpression. |
2007-11-06 |
2023-08-12 |
mouse |
| Harvey Wong, Randy C Dockens, Lori Pajor, Suresh Yeola, James E Grace, Arlene D Stark, Rebecca A Taub, Frank D Yocca, Robert C Zaczek, Yu-Wen L. 6-Hydroxybuspirone is a major active metabolite of buspirone: assessment of pharmacokinetics and 5-hydroxytryptamine1A receptor occupancy in rats. Drug metabolism and disposition: the biological fate of chemicals. vol 35. issue 8. 2007-11-02. PMID:17494642. |
after intravenous infusions to steady-state levels in plasma, 6-oh-buspirone and buspirone increased 5-hydroxytryptamine (ht)(1a) receptor occupancy in a concentration-dependent manner with ec(50) values of 1.0 +/- 0.3 and 0.38 +/- 0.06 microm in the dorsal raphe and 4.0 +/- 0.6 and 1.5 +/- 0.3 microm in the hippocampus, respectively. |
2007-11-02 |
2023-08-12 |
rat |