| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F I Tarazi, T Moran-Gates, E H F Wong, B Henry, M Shahi. Asenapine induces differential regional effects on serotonin receptor subtypes. Journal of psychopharmacology (Oxford, England). vol 24. issue 3. 2010-06-03. PMID:18719049. |
asenapine 0.1 and 0.3 mg/kg significantly increased 5-ht(1a) binding in mpfc (by 24% and 33%, respectively), dfc (27%, 31%) and hippocampal ca(1) region (23%, 25%) (all p < 0.05). |
2010-06-03 |
2023-08-12 |
rat |
| Shao-hua Wang, Zhi-jun Zhang, Yi-jing Guo, Yu-xiu Sui, Yi Su. Involvement of serotonin neurotransmission in hippocampal neurogenesis and behavioral responses in a rat model of post-stroke depression. Pharmacology, biochemistry, and behavior. vol 95. issue 1. 2010-06-01. PMID:20045434. |
involvement of serotonin neurotransmission in hippocampal neurogenesis and behavioral responses in a rat model of post-stroke depression. |
2010-06-01 |
2023-08-12 |
rat |
| Trisha A Jenkins, Jennifer J Elliott, Tara C Ardis, Marie Cahir, Gavin P Reynolds, Robert Bell, Stephen J Coope. Tryptophan depletion impairs object-recognition memory in the rat: reversal by risperidone. Behavioural brain research. vol 208. issue 2. 2010-05-25. PMID:20043957. |
chronically tryptophan-depleted rats had impaired object-recognition memory; this was accompanied by a reduction in central serotonin of 40-50% in the hippocampus, frontal cortex and striatum. |
2010-05-25 |
2023-08-12 |
rat |
| Cecilie L Licht, Lisbeth Kirkegaard, Maha Zueger, Sabine Chourbaji, Peter Gass, Susana Aznar, Gitte M Knudse. Changes in 5-HT4 receptor and 5-HT transporter binding in olfactory bulbectomized and glucocorticoid receptor heterozygous mice. Neurochemistry international. vol 56. issue 4. 2010-05-25. PMID:20060867. |
after bulbectomy, 5-ht(4) receptor binding was increased in the ventral hippocampus (12%) but unchanged in the dorsal hippocampus, frontal and caudal caudate putamen. |
2010-05-25 |
2023-08-12 |
mouse |
| Cecilie L Licht, Lisbeth Kirkegaard, Maha Zueger, Sabine Chourbaji, Peter Gass, Susana Aznar, Gitte M Knudse. Changes in 5-HT4 receptor and 5-HT transporter binding in olfactory bulbectomized and glucocorticoid receptor heterozygous mice. Neurochemistry international. vol 56. issue 4. 2010-05-25. PMID:20060867. |
in comparison, gr(+/-) mice had increased 5-ht(4) receptor (11%) binding in the caudal caudate putamen and decreased 5-htt binding in the frontal caudate putamen but no changes in dorsal and ventral hippocampus. |
2010-05-25 |
2023-08-12 |
mouse |
| Shuichi Ueda, Kanji Yoshimoto, Taro Kadowaki, Koichi Hirata, Shin-ichi Sakakibar. Improved learning in microencephalic rats. Congenital anomalies. vol 50. issue 1. 2010-05-24. PMID:20201969. |
depletion of serotonin in the rat hippocampus is known to influence spatial memory and adult neurogenesis, suggesting a role for serotonin in these processes. |
2010-05-24 |
2023-08-12 |
human |
| Shuichi Ueda, Kanji Yoshimoto, Taro Kadowaki, Koichi Hirata, Shin-ichi Sakakibar. Improved learning in microencephalic rats. Congenital anomalies. vol 50. issue 1. 2010-05-24. PMID:20201969. |
injection of 5,7-dihydroxytryptamine during the neonatal period caused pronounced reductions in hippocampal serotonin levels in these rats. |
2010-05-24 |
2023-08-12 |
human |
| Shuichi Ueda, Kanji Yoshimoto, Taro Kadowaki, Koichi Hirata, Shin-ichi Sakakibar. Improved learning in microencephalic rats. Congenital anomalies. vol 50. issue 1. 2010-05-24. PMID:20201969. |
the present results suggest that ee alleviates spatial memory performance deficits in microencephalic rats and further indicate that serotonin might be involved in the underlying mechanisms through increased hippocampal neurogenesis. |
2010-05-24 |
2023-08-12 |
human |
| Julie G Hensler, Miriam A Vogt, Peter Gas. Regulation of cortical and hippocampal 5-HT(1A) receptor function by corticosterone in GR+/- mice. Psychoneuroendocrinology. vol 35. issue 3. 2010-05-07. PMID:19766402. |
regulation of cortical and hippocampal 5-ht(1a) receptor function by corticosterone in gr+/- mice. |
2010-05-07 |
2023-08-12 |
mouse |
| Julie G Hensler, Miriam A Vogt, Peter Gas. Regulation of cortical and hippocampal 5-HT(1A) receptor function by corticosterone in GR+/- mice. Psychoneuroendocrinology. vol 35. issue 3. 2010-05-07. PMID:19766402. |
our objective in the present study was to examine 5-ht(1a) receptor function in prefrontal cortex and hippocampus of gr+/- mice, which appear to be an appropriate murine model of depression. |
2010-05-07 |
2023-08-12 |
mouse |
| Julie G Hensler, Miriam A Vogt, Peter Gas. Regulation of cortical and hippocampal 5-HT(1A) receptor function by corticosterone in GR+/- mice. Psychoneuroendocrinology. vol 35. issue 3. 2010-05-07. PMID:19766402. |
corticosterone treatment (10mg/kg, sc once daily for 21 days) of wild-type mice resulted in a decrease in 5-ht(1a) receptor function in prefrontal cortex [8-oh-dpat-stimulated [(35)s]gtpgammas binding (% above basal), vehicle-treated: 39+/-4.9; corticosterone-treated: 17+/-2.8], but not in hippocampus. |
2010-05-07 |
2023-08-12 |
mouse |
| Julie G Hensler, Miriam A Vogt, Peter Gas. Regulation of cortical and hippocampal 5-HT(1A) receptor function by corticosterone in GR+/- mice. Psychoneuroendocrinology. vol 35. issue 3. 2010-05-07. PMID:19766402. |
in contrast, corticosterone treatment of gr+/- mice resulted in an increase in 5-ht(1a) receptor function in hippocampus which reached statistical significance in ca2/3 region [8-oh-dpat-stimulated [(35)s]gtpgammas binding (% above basal), vehicle-treated: 41+/-9.7; corticosterone-treated: 94+/-23]. |
2010-05-07 |
2023-08-12 |
mouse |
| Julie G Hensler, Miriam A Vogt, Peter Gas. Regulation of cortical and hippocampal 5-HT(1A) receptor function by corticosterone in GR+/- mice. Psychoneuroendocrinology. vol 35. issue 3. 2010-05-07. PMID:19766402. |
although gr+/- mice do not exhibit changes in baseline corticosterone, the constitutive deficiency in gr appears to have unmasked regulatory effects of elevated corticosterone in the maintenance of 5-ht(1a) receptor function in prefrontal cortex and hippocampus. |
2010-05-07 |
2023-08-12 |
mouse |
| Eva L van Donkelaar, Arjan Blokland, Cindy K J Lieben, Gunter Kenis, Linda Ferrington, Paul A T Kelly, Harry W M Steinbusch, Jos Prickaert. Acute tryptophan depletion in C57BL/6 mice does not induce central serotonin reduction or affective behavioural changes. Neurochemistry international. vol 56. issue 1. 2010-05-04. PMID:19716853. |
a higher dose (2x20 ml/kg) with a longer interval (60 min) reduced the ratio with 68% in c57bl/6 mice, lowered hippocampal serotonin turnover and had no functional effect when tested in the elevated zero-maze and forced swimming test. |
2010-05-04 |
2023-08-12 |
mouse |
| Arata Nakamura, Taro Kadowaki, Shin-ichi Sakakibara, Kanji Yoshimoto, Koichi Hirata, Shuichi Ued. Regeneration of 5-HT fibers in hippocampal heterotopia of methylazoxymethanol-induced micrencephalic rats after neonatal 5,7-DHT injection. Anatomical science international. vol 85. issue 1. 2010-05-03. PMID:19582544. |
regeneration of 5-ht fibers in hippocampal heterotopia of methylazoxymethanol-induced micrencephalic rats after neonatal 5,7-dht injection. |
2010-05-03 |
2023-08-12 |
rat |
| Hei-Jen Huang, Keng-Chen Liang, Yen-Yu Chang, Hsing-Chieh Ke, Jia-Yu Lin, Hsiu Mei Hsieh-L. The interaction between acute oligomer Abeta(1-40) and stress severely impaired spatial learning and memory. Neurobiology of learning and memory. vol 93. issue 1. 2010-04-29. PMID:19660564. |
changes in the components of the hypothalamic-pituitary-adrenal (hpa) axis, such as the gr/mr ratio and crf-1 level, were observed, accompanied by increasing abeta accumulation, oxidative stress, nuclear transcription factor (nf-kappab) hypoactivity, and apoptotic signaling in the hippocampus, and decreasing calbindin d28k and nmda receptor 2a/2b (nr2a/2b) in the hippocampus, along with alteration of the cholinergic neurons (chat) in the medium septum/diagnoid band (ms/db), noradrenergic neurons (th) in the locus coeruleus (lc), and serotonergic neurons (5-ht) in the raphe nucleus. |
2010-04-29 |
2023-08-12 |
mouse |
| A Huerta-Rivas, G Pérez-García, C González-Espinosa, A Menese. Time-course of 5-HT(6) receptor mRNA expression during memory consolidation and amnesia. Neurobiology of learning and memory. vol 93. issue 1. 2010-04-29. PMID:19733250. |
changes in mrna expression of 5-ht(6) receptor were investigated at different times in prefrontal cortex, hippocampus and striatum. |
2010-04-29 |
2023-08-12 |
rat |
| A Huerta-Rivas, G Pérez-García, C González-Espinosa, A Menese. Time-course of 5-HT(6) receptor mRNA expression during memory consolidation and amnesia. Neurobiology of learning and memory. vol 93. issue 1. 2010-04-29. PMID:19733250. |
these data confirmed previous memory evidence and of more interest is the observation that training, sb-399885 and amnesic drugs modulated 5-ht(6) receptor mrna expression in prefrontal cortex, hippocampus and striatum. |
2010-04-29 |
2023-08-12 |
rat |
| Jens Benninghoff, Angela Gritti, Matteo Rizzi, Giuseppe Lamorte, Robert J Schloesser, Angelika Schmitt, Stefanie Robel, Just Genius, Rainald Moessner, Peter Riederer, Husseini K Manji, Heinz Grunze, Dan Rujescu, Hans-Juergen Moeller, Klaus-Peter Lesch, Angelo Luigi Vescov. Serotonin depletion hampers survival and proliferation in neurospheres derived from adult neural stem cells. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 4. 2010-04-28. PMID:20010549. |
serotonin (5-ht) and the serotonergic system have recently been indicated as modulators of adult hippocampal neurogenesis. |
2010-04-28 |
2023-08-12 |
mouse |
| R Rodsiri, A R Green, C A Marsden, K C F Fon. Effect of acute brain tyrosine depletion on MDMA-induced changes in brain 5-HT. Journal of psychopharmacology (Oxford, England). vol 24. issue 2. 2010-04-26. PMID:19965941. |
the long-term neurotoxic 5-ht loss in the hippocampus induced two weeks after mdma administration was unaltered by the tyrosine-free amino acid mixture. |
2010-04-26 |
2023-08-12 |
rat |