| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Haghir, S Kovac, E-J Speckmann, K Zilles, A Gorj. Patterns of neurotransmitter receptor distributions following cortical spreading depression. Neuroscience. vol 163. issue 4. 2010-02-12. PMID:19665048. |
in addition to up-regulation of ionotropic glutamate receptors, receptor binding sites of gaba(a), muscarinic m1 and m2, adrenergic alpha(1) and alpha(2), and serotonergic 5-ht(2) receptors were increased in the hippocampus. |
2010-02-12 |
2023-08-12 |
rat |
| Tae-Soo Kim, Il-Gyu Ko, Yun-Hee Sung, Sung-Eun Kim, Bo-Kyun Kim, Seung-Kook Park, Mal-Soon Shin, Chang-Ju Kim, Sang-Jin Yoon, Khae-Hawn Ki. Vardenafil increases cell proliferation in the dentate gyrus through enhancement of serotonin expression in the rat dorsal raphe. Journal of Korean medical science. vol 24. issue 6. 2010-01-27. PMID:19949666. |
this study was conducted to evaluate the effects of vardenafil (levitra), a phosphodiesterase-5 (pde-5) inhibitor, on cell proliferation in the hippocampal dentate gyrus and on 5-hyroxytryptamine (5-ht, serotonin) synthesis and tryptophan hydroxylase (tph) expression in the rat dorsal raphe nucleus. |
2010-01-27 |
2023-08-12 |
rat |
| Amal A Kinaw. Impact of gasoline inhalation on some neurobehavioural characteristics of male rats. BMC physiology. vol 9. 2010-01-26. PMID:19930677. |
the impacts of gasoline exposure on na+, k+-atpase, superoxide dismutase (sod), acetylcholinesterase (ache), total protein, reduced glutathione (gsh), and lipid peroxidation (tbars) in the cerebral cortex, and monoamine neurotransmitters dopamine (da), norepinephrine (ne) and serotonin (5-ht) in the cerebral cortex, hippocampus, cerebellum and hypothalamus were evaluated. |
2010-01-26 |
2023-08-12 |
rat |
| C Spindelegger, R Lanzenberger, W Wadsak, L K Mien, P Stein, M Mitterhauser, U Moser, A Holik, L Pezawas, K Kletter, S Kaspe. Influence of escitalopram treatment on 5-HT 1A receptor binding in limbic regions in patients with anxiety disorders. Molecular psychiatry. vol 14. issue 11. 2010-01-25. PMID:18362913. |
5-ht(1a) receptor binding potentials in 12 patients were assessed by pet applying the simplified reference tissue model.there was a significant reduction in the 5-ht(1a) receptor binding potential after a minimum of 12 weeks of escitalopram treatment in the hippocampus (p=0.006), subgenual cortex (p=0.017) and posterior cingulate cortex (p=0.034). |
2010-01-25 |
2023-08-12 |
Not clear |
| Shao-hua Wang, Zhi-jun Zhang, Yi-jing Guo, Gao-jun Teng, Bao-an Che. Decreased expression of serotonin 1A receptor in the dentate gyrus in association with chronic mild stress: a rat model of post-stroke depression. Psychiatry research. vol 170. issue 2-3. 2010-01-21. PMID:19896211. |
here we investigated the expression of the 5-ht(1a) receptor and gene in the hippocampal dentate gyrus (dg) by chronic mild stress (cms) after stroke and the effect of citalopram. |
2010-01-21 |
2023-08-12 |
rat |
| Jean Lud Cadet, Irina N Krasnova, Bruce Ladenheim, Ning-Sheng Cai, Michael T McCoy, Fidelis E Atianjo. Methamphetamine preconditioning: differential protective effects on monoaminergic systems in the rat brain. Neurotoxicity research. vol 15. issue 3. 2010-01-08. PMID:19384598. |
in contrast, there was no preconditioning-mediated protection against meth-induced serotonin depletion in the striatum and hippocampus, with some protection being observed in the cortex. |
2010-01-08 |
2023-08-12 |
human |
| Atsuko Kimura, Paula L Stevenson, Roderick N Carter, Gavin Maccoll, Karen L French, J Paul Simons, Raya Al-Shawi, Valerie Kelly, Karen E Chapman, Megan C Holme. Overexpression of 5-HT2C receptors in forebrain leads to elevated anxiety and hypoactivity. The European journal of neuroscience. vol 30. issue 2. 2010-01-08. PMID:19614978. |
transgenic mice overexpressing 5-ht(2c) receptors under the control of the camkiialpha promoter (c2cr mice) have elevated 5-ht(2c) receptor mrna levels in cerebral cortex and limbic areas (including the hippocampus and amygdala), but normal levels in the hypothalamus, resulting in > 100% increase in the number of 5-ht(2c) ligand binding sites in the forebrain. |
2010-01-08 |
2023-08-12 |
mouse |
| Pushpendra Singh, Roopali Saxena, Yamuna Devi Paila, Md Jafurulla, Amitabha Chattopadhya. Differential effects of cholesterol and desmosterol on the ligand binding function of the hippocampal serotonin(1A) receptor: implications in desmosterolosis. Biochimica et biophysica acta. vol 1788. issue 10. 2009-12-22. PMID:19616511. |
differential effects of cholesterol and desmosterol on the ligand binding function of the hippocampal serotonin(1a) receptor: implications in desmosterolosis. |
2009-12-22 |
2023-08-12 |
Not clear |
| Pushpendra Singh, Roopali Saxena, Yamuna Devi Paila, Md Jafurulla, Amitabha Chattopadhya. Differential effects of cholesterol and desmosterol on the ligand binding function of the hippocampal serotonin(1A) receptor: implications in desmosterolosis. Biochimica et biophysica acta. vol 1788. issue 10. 2009-12-22. PMID:19616511. |
we previously demonstrated the requirement of membrane cholesterol in maintaining the ligand binding activity of the hippocampal serotonin(1a) receptor. |
2009-12-22 |
2023-08-12 |
Not clear |
| M Grabowska-Andén, A Smialowsk. The influence of intracaudate injection of apomorphine on metabolism of serotonin in hippocampus and mesencephalon of the rabbit. Neuroscience letters. vol 6. issue 2-3. 2009-12-16. PMID:19605051. |
the influence of intracaudate injection of apomorphine on metabolism of serotonin in hippocampus and mesencephalon of the rabbit. |
2009-12-16 |
2023-08-12 |
rabbit |
| M Kuramochi, S Nakamur. Effects of postnatal isolation rearing and antidepressant treatment on the density of serotonergic and noradrenergic axons and depressive behavior in rats. Neuroscience. vol 163. issue 1. 2009-12-15. PMID:19524023. |
postweaning social iso rearing reduced the density of 5-ht axons in the central nucleus and basolateral nucleus of the amygdala and ca3 of the hippocampus. |
2009-12-15 |
2023-08-12 |
rat |
| M Kuramochi, S Nakamur. Effects of postnatal isolation rearing and antidepressant treatment on the density of serotonergic and noradrenergic axons and depressive behavior in rats. Neuroscience. vol 163. issue 1. 2009-12-15. PMID:19524023. |
in the prelimbic area and infralimbic area of medial prefrontal cortex and the dentate gyrus of the hippocampus, the density of 5-ht axons was not affected by social iso alone, but was reduced when animals were socially isolated after neonatal cl treatment. |
2009-12-15 |
2023-08-12 |
rat |
| Kebreten F Manaye, Paul C Wang, Jahn N O'Neil, Sophia Y Huang, Tao Xu, De-Liang Lei, Yousef Tizabi, Mary Ann Ottinger, Donald K Ingram, Peter R Mouto. Neuropathological quantification of dtg APP/PS1: neuroimaging, stereology, and biochemistry. Age (Dordrecht, Netherlands). vol 29. issue 2-3. 2009-12-14. PMID:19424834. |
in addition, levels of norepinephrine (ne), dopamine (da), serotonin (5-ht) and 5-ht metabolites were assayed by hplc in fresh-frozen samples from neocortex, striatum, hippocampus, and brainstem. |
2009-12-14 |
2023-08-12 |
mouse |
| E L van Donkelaar, L Ferrington, A Blokland, H W M Steinbusch, J Prickaerts, P A T Kell. Acute tryptophan depletion in rats alters the relationship between cerebral blood flow and glucose metabolism independent of central serotonin. Neuroscience. vol 163. issue 2. 2009-12-14. PMID:19580853. |
in plasma, atd resulted in a 40% reduction in the ratio of trp to the sum of other large neutral amino acids, but had no measurable effect upon trp or 5-ht levels in hippocampus or prefrontal cortex. |
2009-12-14 |
2023-08-12 |
rat |
| Roberta J Ward, Maria Alessandra Colivicchi, Rachel Allen, François Schol, Frédéric Lallemand, Philippe de Witte, Chiara Ballini, Laura Della Corte, David Dexte. Neuro-inflammation induced in the hippocampus of 'binge drinking' rats may be mediated by elevated extracellular glutamate content. Journal of neurochemistry. vol 111. issue 5. 2009-12-11. PMID:19765190. |
in contrast, no changes in the hippocampal extracellular concentrations, of gaba and taurine, or the dopamine and serotonin metabolites were observed under basal conditions. |
2009-12-11 |
2023-08-12 |
rat |
| Amélie Soumier, Mounira Banasr, Sylviane Lortet, Frédérique Masmejean, Nathalie Bernard, Lydia Kerkerian-Le-Goff, Cecilia Gabriel, Mark J Millan, Elisabeth Mocaer, Annie Daszut. Mechanisms contributing to the phase-dependent regulation of neurogenesis by the novel antidepressant, agomelatine, in the adult rat hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 11. 2009-12-07. PMID:19571795. |
these results show that agomelatine treatment facilitates all stages of neurogenesis and suggest that a joint effect of melatonin agonism and 5ht(2c) antagonism may be involved in promotion by agomelatine of survival in the hippocampus. |
2009-12-07 |
2023-08-12 |
rat |
| Amee Krishnakumar, M S Nandhu, C S Paulos. Upregulation of 5-HT2C receptors in hippocampus of pilocarpine-induced epileptic rats: antagonism by Bacopa monnieri. Epilepsy & behavior : E&B. vol 16. issue 2. 2009-12-07. PMID:19700373. |
the present study was carried out to investigate the role of bacopa monnieri extract in hippocampus of pilocarpine-induced temporal lobe epileptic rats through the 5-ht(2c) receptor in relation to depression. |
2009-12-07 |
2023-08-12 |
rat |
| Amee Krishnakumar, M S Nandhu, C S Paulos. Upregulation of 5-HT2C receptors in hippocampus of pilocarpine-induced epileptic rats: antagonism by Bacopa monnieri. Epilepsy & behavior : E&B. vol 16. issue 2. 2009-12-07. PMID:19700373. |
our results showed upregulation of 5-ht(2c) receptors with a decreased affinity in hippocampus of pilocarpine-induced epileptic rats. |
2009-12-07 |
2023-08-12 |
rat |
| Amee Krishnakumar, M S Nandhu, C S Paulos. Upregulation of 5-HT2C receptors in hippocampus of pilocarpine-induced epileptic rats: antagonism by Bacopa monnieri. Epilepsy & behavior : E&B. vol 16. issue 2. 2009-12-07. PMID:19700373. |
also, there was an increase in 5-ht(2c) gene expression and inositol triphosphate content in epileptic hippocampus. |
2009-12-07 |
2023-08-12 |
rat |
| Lin Li, Nigel Whittle, Stefanie Klug, Wei-Qiang Chen, Nicolas Singewald, Miklos Toth, Gert Lube. Serotonin(1A)-receptor-dependent signaling proteins in mouse hippocampus. Neuropharmacology. vol 57. issue 5-6. 2009-12-04. PMID:19607848. |
serotonin(1a)-receptor-dependent signaling proteins in mouse hippocampus. |
2009-12-04 |
2023-08-12 |
mouse |