| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eleonora Calcagno, Sara Guzzetti, Alessandro Canetta, Claudia Fracasso, Silvio Caccia, Luigi Cervo, Roberto W Invernizz. Enhancement of cortical extracellular 5-HT by 5-HT1A and 5-HT2C receptor blockade restores the antidepressant-like effect of citalopram in non-responder mice. The international journal of neuropsychopharmacology. vol 12. issue 6. 2009-08-18. PMID:19123962. |
the 5-ht receptor antagonists had no effect on the citalopram-induced increase in extracellular 5-ht in the dorsal hippocampus. |
2009-08-18 |
2023-08-12 |
mouse |
| Thomas Wultsch, Gundula Grimberg, Angelika Schmitt, Evelin Painsipp, Heike Wetzstein, Alexandra Frauke Stephanie Breitenkamp, Dirk Gründemann, Edgar Schömig, Klaus-Peter Lesch, Manfred Gerlach, Andreas Rei. Decreased anxiety in mice lacking the organic cation transporter 3. Journal of neural transmission (Vienna, Austria : 1996). vol 116. issue 6. 2009-08-18. PMID:19280114. |
interestingly, oct3 mrna is however also significantly up-regulated in the hippocampus of serotonin transporter knockout mice where it might serve as an alternative reuptake mechanism for serotonin. |
2009-08-18 |
2023-08-12 |
mouse |
| Jonathan Savitz, Irwin Lucki, Wayne C Drevet. 5-HT(1A) receptor function in major depressive disorder. Progress in neurobiology. vol 88. issue 1. 2009-08-18. PMID:19428959. |
reduced somatodendritic and postsynaptic 5-ht(1a) receptor numbers or affinity have been reported in some post-mortem studies of suicide victims, a result consistent with well-replicated pet analyses demonstrating reduced 5-ht(1a) receptor binding potential in diverse regions such as the dorsal raphe, medial prefrontal cortex (mpfc), amygdala and hippocampus. |
2009-08-18 |
2023-08-12 |
mouse |
| Arindam Dalal, Mrinal K Podda. Short-term erythrosine B-induced inhibition of the brain regional serotonergic activity suppresses motor activity (exploratory behavior) of young adult mammals. Pharmacology, biochemistry, and behavior. vol 92. issue 4. 2009-08-14. PMID:19264092. |
of erythrosine administration to young adult male rats reduced motor activity (ma) maximally at 2 h and brain regional (medulla-pons, hippocampus and hypothalamus) serotonergic activity (measuring steady-state levels of 5-ht and 5-hiaa, pargyline-induced 5-ht accumulation and 5-hiaa declination rate and 5-ht receptor binding) under similar experimental condition. |
2009-08-14 |
2023-08-12 |
rat |
| Frank Neugebauer, Volker Korz, Julietta U Fre. Modulation of extracellular monoamine transmitter concentrations in the hippocampus after weak and strong tetanization of the perforant path in freely moving rats. Brain research. vol 1273. 2009-08-14. PMID:19345680. |
a weak tetanus of the perforant path, which normally leads to early-ltp, transiently but significantly decreased the concentration of na (3 h) and increased the concentration of 5-ht (about 2 h) and da (about 1 h) in the hippocampus. |
2009-08-14 |
2023-08-12 |
rat |
| Alex G Rodrigues, Danusa D Soares, Umeko Marubayashi, Cândido Celso Coimbr. Heat loss during exercise is related to serotonin activity in the preoptic area. Neuroreport. vol 20. issue 8. 2009-08-14. PMID:19369904. |
at fatigue, brains were quickly removed and serotonin and 5-hydroxyindoleacetic acid were measured in the preoptic area, hypothalamus, frontal cortex, and hippocampus. |
2009-08-14 |
2023-08-12 |
rat |
| Li-Tao Yi, Qun Xu, Yu-Cheng Li, Lei Yang, Ling-Dong Kon. Antidepressant-like synergism of extracts from magnolia bark and ginger rhizome alone and in combination in mice. Progress in neuro-psychopharmacology & biological psychiatry. vol 33. issue 4. 2009-08-10. PMID:19285110. |
serotonin (5-ht) and noradrenaline (ne) levels in prefrontal cortex, hippocampus and striatum were also examined. |
2009-08-10 |
2023-08-12 |
mouse |
| Jonathan G McEuen, Katharine A Semsar, Maria A Lim, Tracy L Bal. Influence of sex and corticotropin-releasing factor pathways as determinants in serotonin sensitivity. Endocrinology. vol 150. issue 8. 2009-08-05. PMID:19342454. |
mechanistically, females had decreased hippocampal 5-ht transporter (sert) levels, whereas r2ko mice showed reduced sert in the prefrontal cortex, supporting a possible intersection of sex and genotype where r2ko females would have the lowest sert to be blocked by the ssri. |
2009-08-05 |
2023-08-12 |
mouse |
| Hideki Miura, Tetsuya Shirokawa, Kenichi Isobe, Norio Ozak. Shifting the balance of brain tryptophan metabolism elicited by isolation housing and systemic administration of lipopolysaccharide in mice. Stress (Amsterdam, Netherlands). vol 12. issue 3. 2009-08-03. PMID:19006008. |
we measured the trp, kyn, and 5-ht levels in the prefrontal cortex, hippocampus, amygdala, and dorsal raphe nuclei. |
2009-08-03 |
2023-08-12 |
mouse |
| Satoshi Yamamura, Tatsuya Hamaguchi, Keiko Ohoyama, Yoshihiro Sugiura, Dai Suzuki, Shinich Kanehara, Masanori Nakagawa, Eishi Motomura, Takuya Matsumoto, Hisashi Tanii, Takashi Shiroyama, Motohiro Okad. Topiramate and zonisamide prevent paradoxical intoxication induced by carbamazepine and phenytoin. Epilepsy research. vol 84. issue 2-3. 2009-07-24. PMID:19268540. |
the dose-dependent effects of aeds on hippocampal extracellular levels of glutamate (glu), gaba, norepinephrine (ne), dopamine (da), and serotonin (5-ht) were determined by microdialysis with high-speed and high-sensitive extreme liquid chromatography. |
2009-07-24 |
2023-08-12 |
rat |
| Satoshi Yamamura, Tatsuya Hamaguchi, Keiko Ohoyama, Yoshihiro Sugiura, Dai Suzuki, Shinich Kanehara, Masanori Nakagawa, Eishi Motomura, Takuya Matsumoto, Hisashi Tanii, Takashi Shiroyama, Motohiro Okad. Topiramate and zonisamide prevent paradoxical intoxication induced by carbamazepine and phenytoin. Epilepsy research. vol 84. issue 2-3. 2009-07-24. PMID:19268540. |
therapeutically relevant doses of azm, cbz, tpm, and zns increased hippocampal extracellular levels of gaba, ne, da, and 5-ht, while pht had no effect. |
2009-07-24 |
2023-08-12 |
rat |
| Abeer M Wagga. Neuroprotective evaluation of extract of ginger (Zingiber officinale) root in monosodium glutamate-induced toxicity in different brain areas male albino rats. Pakistan journal of biological sciences : PJBS. vol 12. issue 3. 2009-07-23. PMID:19579948. |
injection of pure monosodium glutamate (msg) for 30 days and subsequent withdrawal caused a significant decrease in epinephrine (e), norepinephrine (ne), dopamine (da) and serotonin (5-ht) content all tested areas (cerebellum, brainstem, striatum, cerebral cortex, hypothalamus and hippocampus) at most of the time intervals studied. |
2009-07-23 |
2023-08-12 |
rat |
| Francis Rodriguez Bambico, Andrea Duranti, Andrea Tontini, Giorgio Tarzia, Gabriella Gobb. Endocannabinoids in the treatment of mood disorders: evidence from animal models. Current pharmaceutical design. vol 15. issue 14. 2009-07-20. PMID:19442178. |
in particular, all antidepressants increase the neurotransmission of serotonin after long-term treatment, enhance the tonic activity of hippocampal 5-ht(1a) receptors, promote neurogenesis, and modulate (decrease or increase) the firing activity of noradrenergic neurons. |
2009-07-20 |
2023-08-12 |
mouse |
| Francis Rodriguez Bambico, Andrea Duranti, Andrea Tontini, Giorgio Tarzia, Gabriella Gobb. Endocannabinoids in the treatment of mood disorders: evidence from animal models. Current pharmaceutical design. vol 15. issue 14. 2009-07-20. PMID:19442178. |
interestingly, cannabinoid agonists and endocannabinoid enhancers increase serotonin and noradrenergic neuronal firing activity, increase serotonin release in the hippocampus, as well as promote neurogenesis. |
2009-07-20 |
2023-08-12 |
mouse |
| Falk Leichsenring, Simone Salzer, Manfred E Beutel, Katrin von Consbruch, Stephan Herpertz, Wolfgang Hiller, Jürgen Hoyer, Johannes Hüsing, Eva Irle, Peter Joraschky, Alexander Konnopka, Hans-Helmut König, Therese de Liz, Björn Nolting, Karin Pöhlmann, Mirjana Ruhleder, Henning Schauenburg, Ulrich Stangier, Bernhard Strauss, Claudia Subic-Wrana, Stefan V Vormfelde, Godehard Weniger, Ulrike Willutzki, Jörg Wiltink, Eric Leibin. [SOPHO-NET - a research network on psychotherapy for social phobia]. Psychotherapie, Psychosomatik, medizinische Psychologie. vol 59. issue 3-4. 2009-07-15. PMID:19350471. |
study a is complemented by four interrelated projects focusing on attachment style (study b1), cost-effectiveness (study b2), polymorphisms in the serotonin transporter gene (study c1) and on structural and functional deviations of hippocampus and amygdala (study c2). |
2009-07-15 |
2023-08-12 |
Not clear |
| Przemysław Nowak, Dariusz Nitka, Adam Kwieciński, Jadwiga Jośko, Jacek Drab, Dorota Pojda-Wilczek, Jacek Kasperski, Richard M Kostrzewa, Ryszard Bru. Neonatal co-lesion by DSP-4 and 5,7-DHT produces adulthood behavioral sensitization to dopamine D(2) receptor agonists. Pharmacological reports : PR. vol 61. issue 2. 2009-07-14. PMID:19443944. |
at eight weeks, using an hplc/ed technique, dsp-4 treatment was associated with a reduction in ne content of the corpus striatum (> 60%), hippocampus (95%), and frontal cortex (> 85%), while 5,7-dht was associated with an 80-90% serotonin reduction in the same brain regions. |
2009-07-14 |
2023-08-12 |
rat |
| Yi Zhu, Qun-ying Liu, Lian-shi Zhu. [Influence of electroacupuncture of "Baihui" (GV 20) and "Sanyinjiao" (SP 6) on hippocampal 5-HT and AChE immuno-activity in chronic depression rats]. Zhen ci yan jiu = Acupuncture research. vol 34. issue 1. 2009-07-09. PMID:19526802. |
[influence of electroacupuncture of "baihui" (gv 20) and "sanyinjiao" (sp 6) on hippocampal 5-ht and ache immuno-activity in chronic depression rats]. |
2009-07-09 |
2023-08-12 |
rat |
| Yi Zhu, Qun-ying Liu, Lian-shi Zhu. [Influence of electroacupuncture of "Baihui" (GV 20) and "Sanyinjiao" (SP 6) on hippocampal 5-HT and AChE immuno-activity in chronic depression rats]. Zhen ci yan jiu = Acupuncture research. vol 34. issue 1. 2009-07-09. PMID:19526802. |
to investigate the influence of electroacupuncture (ea) on 5-serotonin (5-ht) and acetyl cholinesterase (ache) activities in hippocampus tissue in chronic stressed-induced depression rats. |
2009-07-09 |
2023-08-12 |
rat |
| Marie-Bernadette Assié, Ouissame Mnie-Filali, Véronique Ravailhe, Christelle Benas, Marc Marien, Cécile Bétry, Luc Zimmer, Nasser Haddjeri, Adrian Newman-Tancred. F15063, a potential antipsychotic with dopamine D2/D3 receptor antagonist, 5-HT1A receptor agonist and dopamine D4 receptor partial agonist properties: influence on neuronal firing and neurotransmitter release. European journal of pharmacology. vol 607. issue 1-3. 2009-07-07. PMID:19326477. |
further, we investigated the modulation of extracellular dopamine and noradrenaline in the medial prefrontal cortex and serotonin in the hippocampus of freely moving rats by f15063 using in vivo microdialysis. |
2009-07-07 |
2023-08-12 |
rat |
| Marie-Bernadette Assié, Ouissame Mnie-Filali, Véronique Ravailhe, Christelle Benas, Marc Marien, Cécile Bétry, Luc Zimmer, Nasser Haddjeri, Adrian Newman-Tancred. F15063, a potential antipsychotic with dopamine D2/D3 receptor antagonist, 5-HT1A receptor agonist and dopamine D4 receptor partial agonist properties: influence on neuronal firing and neurotransmitter release. European journal of pharmacology. vol 607. issue 1-3. 2009-07-07. PMID:19326477. |
dose-dependently increased dopamine levels in the prefrontal cortex and decreased hippocampal 5-ht. |
2009-07-07 |
2023-08-12 |
rat |