| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yong Kee Choi, Taylor Moran-Gates, Matthew P Gardner, Frank I Taraz. Effects of repeated risperidone exposure on serotonin receptor subtypes in developing rats. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 20. issue 3. 2010-08-31. PMID:19875272. |
the higher doses (1.0 and 3.0mg/kg) of risperidone also increased 5-ht(1a) receptor binding in hippocampal ca(1) region of juvenile but not adult rats. |
2010-08-31 |
2023-08-12 |
rat |
| Hideyuki Inoue, Hidenori Yamasue, Mamoru Tochigi, Kunio Takei, Motomu Suga, Osamu Abe, Haruyasu Yamada, Mark A Rogers, Shigeki Aoki, Tsukasa Sasaki, Kiyoto Kasa. Effect of tryptophan hydroxylase-2 gene variants on amygdalar and hippocampal volumes. Brain research. vol 1331. 2010-08-20. PMID:20331984. |
these results suggest that amygdalar and hippocampal volumes assessed using mri may be a useful intermediate phenotype that will uncover the biological pathway linking 5-ht synthesis and emotional behaviors and affective disorders. |
2010-08-20 |
2023-08-12 |
human |
| R M Freitas, J Jordán, D Fen. Lipoic acid effects on monoaminergic system after pilocarpine-induced seizures. Neuroscience letters. vol 477. issue 3. 2010-08-20. PMID:20433896. |
the purpose of this work was to determine the effects of lipoic acid (la) on the levels of dopamine (da), serotonin (5-ht), norepinephrine (ne) and subsequent metabolites in the hippocampus of rats after seizure induction by pilocarpine. |
2010-08-20 |
2023-08-12 |
rat |
| Lucinéia dos Santos, Telma G C S de Andrade, Frederico G Graef. Social separation and diazepam withdrawal increase anxiety in the elevated plus-maze and serotonin turnover in the median raphe and hippocampus. Journal of psychopharmacology (Oxford, England). vol 24. issue 5. 2010-08-18. PMID:19939879. |
social separation and diazepam withdrawal increase anxiety in the elevated plus-maze and serotonin turnover in the median raphe and hippocampus. |
2010-08-18 |
2023-08-12 |
rat |
| Lucinéia dos Santos, Telma G C S de Andrade, Frederico G Graef. Social separation and diazepam withdrawal increase anxiety in the elevated plus-maze and serotonin turnover in the median raphe and hippocampus. Journal of psychopharmacology (Oxford, England). vol 24. issue 5. 2010-08-18. PMID:19939879. |
separation also selectively increased 5-hydroxytryptamine turnover in the hippocampus and median raphe nucleus. |
2010-08-18 |
2023-08-12 |
rat |
| Priya Ranjan Debata, Buddima Ranasinghe, Alexandra Berliner, Gina Marie Curcio, Subramanyam J Tantry, Evgeni Ponimaskin, Probal Banerje. Erk1/2-dependent phosphorylation of PKCalpha at threonine 638 in hippocampal 5-HT(1A) receptor-mediated signaling. Biochemical and biophysical research communications. vol 397. issue 3. 2010-08-12. PMID:20513439. |
erk1/2-dependent phosphorylation of pkcalpha at threonine 638 in hippocampal 5-ht(1a) receptor-mediated signaling. |
2010-08-12 |
2023-08-12 |
mouse |
| Priya Ranjan Debata, Buddima Ranasinghe, Alexandra Berliner, Gina Marie Curcio, Subramanyam J Tantry, Evgeni Ponimaskin, Probal Banerje. Erk1/2-dependent phosphorylation of PKCalpha at threonine 638 in hippocampal 5-HT(1A) receptor-mediated signaling. Biochemical and biophysical research communications. vol 397. issue 3. 2010-08-12. PMID:20513439. |
stimulation of the serotonin 1a receptor (5-ht(1a)-r) causes activation of extracellular signal-regulated protein kinase (erk) and protein kinase c alpha (pkcalpha) in both hippocampal hn2-5 cells and cultured hippocampal slices from postnatal day-15 (p15) mice. |
2010-08-12 |
2023-08-12 |
mouse |
| W Otten, E Kanitz, D Couret, I Veissier, A Prunier, E Merlo. Maternal social stress during late pregnancy affects hypothalamic-pituitary-adrenal function and brain neurotransmitter systems in pig offspring. Domestic animal endocrinology. vol 38. issue 3. 2010-08-09. PMID:19879712. |
in addition, prenatally stressed piglets showed an increased 5-hydroxyindole-3-acetic acid to 5-hydroxytryptamine ratio in the hippocampus after weaning and increased hippocampal c-fos mrna expression and noradrenaline concentration after relocation (p<0.05). |
2010-08-09 |
2023-08-12 |
Not clear |
| Cecilie Löe Licht, Gitte Moos Knudsen, Trevor Shar. Effects of the 5-HT(4) receptor agonist RS67333 and paroxetine on hippocampal extracellular 5-HT levels. Neuroscience letters. vol 476. issue 2. 2010-07-30. PMID:20381585. |
effects of the 5-ht(4) receptor agonist rs67333 and paroxetine on hippocampal extracellular 5-ht levels. |
2010-07-30 |
2023-08-12 |
rat |
| Cecilie Löe Licht, Gitte Moos Knudsen, Trevor Shar. Effects of the 5-HT(4) receptor agonist RS67333 and paroxetine on hippocampal extracellular 5-HT levels. Neuroscience letters. vol 476. issue 2. 2010-07-30. PMID:20381585. |
this microdialysis study evaluated the effect of the 5-ht(4) receptor agonist, rs67333, on extracellular serotonin (5-hydroxytryptamine, 5-ht) and 5-hiaa levels in rat ventral hippocampus during chloral hydrate anaesthesia, and explored the ability of rs67333 to augment the effect of the selective serotonin reuptake inhibitor paroxetine. |
2010-07-30 |
2023-08-12 |
rat |
| Cecilie Löe Licht, Gitte Moos Knudsen, Trevor Shar. Effects of the 5-HT(4) receptor agonist RS67333 and paroxetine on hippocampal extracellular 5-HT levels. Neuroscience letters. vol 476. issue 2. 2010-07-30. PMID:20381585. |
in conclusion, the 5-ht(4) receptor agonist rs67333 augmented the acute effect of paroxetine on extracellular 5-ht levels in the ventral hippocampus, and after 3 days increased basal hippocampal 5-ht levels. |
2010-07-30 |
2023-08-12 |
rat |
| Patrizia Bianchi, Elisabetta Ciani, Sandra Guidi, Stefania Trazzi, Daniela Felice, Gabriele Grossi, Mercedes Fernandez, Alessandro Giuliani, Laura Calzà, Renata Bartesagh. Early pharmacotherapy restores neurogenesis and cognitive performance in the Ts65Dn mouse model for Down syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 26. 2010-07-22. PMID:20592198. |
in the hippocampus of untreated p15 ts65dn mice, we found normal 5-ht levels but a lower expression of 5-ht1a receptors and brain-derived neurotrophic factor (bdnf). |
2010-07-22 |
2023-08-12 |
mouse |
| Kieran Rea, Joost Folgering, Ben H C Westerink, Thomas I F H Cremer. Alpha1-adrenoceptors modulate citalopram-induced serotonin release. Neuropharmacology. vol 58. issue 7. 2010-07-19. PMID:20043931. |
using microdialysis coupled to hplc, we investigated the effects of alpha1-adrenoceptor manipulation on extracellular serotonin levels - in the ventral hippocampus, prefrontal cortex, and raphe nuclei - in the presence or absence of the serotonin reuptake inhibitor (ssri), citalopram. |
2010-07-19 |
2023-08-12 |
Not clear |
| Kieran Rea, Joost Folgering, Ben H C Westerink, Thomas I F H Cremer. Alpha1-adrenoceptors modulate citalopram-induced serotonin release. Neuropharmacology. vol 58. issue 7. 2010-07-19. PMID:20043931. |
extracellular 5-ht levels from prefrontal cortex, ventral hippocampus and raphe nuclei were markedly increased following citalopram administration (3.0 mg/kg s.c.). |
2010-07-19 |
2023-08-12 |
Not clear |
| Kieran Rea, Joost Folgering, Ben H C Westerink, Thomas I F H Cremer. Alpha1-adrenoceptors modulate citalopram-induced serotonin release. Neuropharmacology. vol 58. issue 7. 2010-07-19. PMID:20043931. |
in the prefrontal cortex and ventral hippocampus, local blockade of the alpha1-adrenoceptor (3.0 microm prazosin infusion) significantly decreased this citalopram-induced increase in serotonin, while cirazoline (alpha1-adrenoceptor agonist) and reboxetine (noradrenaline reuptake inhibitor) further increased extracellular serotonin levels when administered systemically (0.02 mg/kg i.p. |
2010-07-19 |
2023-08-12 |
Not clear |
| Brian J Piper, Syed F Ali, Lauren G Daniels, Jerrold S Meye. Repeated intermittent methylenedioxymethamphetamine exposure protects against the behavioral and neurotoxic, but not hyperthermic, effects of an MDMA binge in adult rats. Synapse (New York, N.Y.). vol 64. issue 6. 2010-07-19. PMID:20169574. |
spontaneous motor activity was determined the next day, and cortical and hippocampal samples were collected at 1 week postbinge to measure serotonin (5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) concentrations as well as [3h]citalopram binding to sert. |
2010-07-19 |
2023-08-12 |
rat |
| Jeffery N Talbot, Emily M Jutkiewicz, Steven M Graves, Crystal F Clemans, Melanie R Nicol, Richard M Mortensen, Xinyan Huang, Richard R Neubig, John R Trayno. RGS inhibition at G(alpha)i2 selectively potentiates 5-HT1A-mediated antidepressant effects. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 24. 2010-07-14. PMID:20534514. |
mice expressing rgs-insensitive g(alpha)i2 also exhibited increased cortical and hippocampal phosphorylation of glycogen synthase kinase-3beta, a constitutively active proapoptotic kinase that is inhibited through phosphorylation in response to serotonin, ssris, and 5-ht1 receptor agonists. |
2010-07-14 |
2023-08-12 |
mouse |
| Yu Ohmura, Takeshi Izumi, Taku Yamaguchi, Iku Tsutsui-Kimura, Takayuki Yoshida, Mitsuhiro Yoshiok. The serotonergic projection from the median raphe nucleus to the ventral hippocampus is involved in the retrieval of fear memory through the corticotropin-releasing factor type 2 receptor. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 6. 2010-07-12. PMID:20072117. |
several different studies have separately established that serotonin, corticotropin-releasing factor (crf) receptors, and the hippocampus are involved in fear memory retrieval. |
2010-07-12 |
2023-08-12 |
rat |
| Yu Ohmura, Takeshi Izumi, Taku Yamaguchi, Iku Tsutsui-Kimura, Takayuki Yoshida, Mitsuhiro Yoshiok. The serotonergic projection from the median raphe nucleus to the ventral hippocampus is involved in the retrieval of fear memory through the corticotropin-releasing factor type 2 receptor. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 6. 2010-07-12. PMID:20072117. |
moreover, when we assessed the extracellular serotonin release in the ventral hippocampus in freely moving rats through in vivo microdialysis, it was shown that the blockade of the crf(2) receptor in the mrn suppressed serotonin release in the ventral hippocampus during fear memory retrieval. |
2010-07-12 |
2023-08-12 |
rat |
| Yu Ohmura, Takeshi Izumi, Taku Yamaguchi, Iku Tsutsui-Kimura, Takayuki Yoshida, Mitsuhiro Yoshiok. The serotonergic projection from the median raphe nucleus to the ventral hippocampus is involved in the retrieval of fear memory through the corticotropin-releasing factor type 2 receptor. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 6. 2010-07-12. PMID:20072117. |
these results indicated that endogenous crf and/or related ligands that were released in the mrn could activate the crf(2) receptor and stimulate serotonin release in the ventral hippocampus, thereby inducing fear memory retrieval. |
2010-07-12 |
2023-08-12 |
rat |