| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yunhong Yu, Wei Xie, Changjun Wan. Chaihushugan decoction exerts antiepileptic effects by increasing hippocampal glutamate metabolism in pentylenetetrazole-kindled rats. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. vol 35. issue 6. 2016-02-09. PMID:26742311. |
chaihushugan decoction exerts antiepileptic effects by increasing hippocampal glutamate metabolism in pentylenetetrazole-kindled rats. |
2016-02-09 |
2023-08-13 |
rat |
| Mari-Carmen Marx, Daniela Billups, Brian Billup. Maintaining the presynaptic glutamate supply for excitatory neurotransmission. Journal of neuroscience research. vol 93. issue 7. 2016-02-05. PMID:25648608. |
diffusion of glutamate from the soma is calculated to be fast enough to resupply presynaptic glutamate in the hippocampus but not at the calyx of held. |
2016-02-05 |
2023-08-13 |
Not clear |
| Mari-Carmen Marx, Daniela Billups, Brian Billup. Maintaining the presynaptic glutamate supply for excitatory neurotransmission. Journal of neuroscience research. vol 93. issue 7. 2016-02-05. PMID:25648608. |
direct presynaptic uptake of glutamate is not present at the calyx of held but may play a role in glutamate recycling in the hippocampus. |
2016-02-05 |
2023-08-13 |
Not clear |
| Ivana Machado, Patricia V Gonzalez, Alejandro Vilcaes, Lila Carniglia, Helgi B Schiöth, Mercedes Lasaga, Teresa N Scimonell. Interleukin-1β-induced memory reconsolidation impairment is mediated by a reduction in glutamate release and zif268 expression and α-melanocyte-stimulating hormone prevented these effects. Brain, behavior, and immunity. vol 46. 2016-02-04. PMID:25637483. |
our results demonstrated that il-1β induced a significant decrease of glutamate release after reactivation of the fear memory and this effect was related to calcium concentration in hippocampal synaptosomes. |
2016-02-04 |
2023-08-13 |
Not clear |
| Enza Palazzo, Rosaria Romano, Livio Luongo, Serena Boccella, Danilo De Gregorio, Maria Elvira Giordano, Francesca Rossi, Ida Marabese, Maria Antonietta Scafuro, Vito de Novellis, Sabatino Maion. MMPIP, an mGluR7-selective negative allosteric modulator, alleviates pain and normalizes affective and cognitive behavior in neuropathic mice. Pain. vol 156. issue 6. 2016-02-04. PMID:25760470. |
mglur7 expression, mainly associated with vesicular glutamate transporter, increased in the hippocampus and decreased in the bla, plc, and dorsal raphe in sni mice. |
2016-02-04 |
2023-08-13 |
mouse |
| Endre Dobó, Ibolya Török, András Mihály, Norbert Károly, Beáta Krisztin-Pév. Interstrain differences of ionotropic glutamate receptor subunits in the hippocampus and induction of hippocampal sclerosis with pilocarpine in mice. Journal of chemical neuroanatomy. vol 64-65. 2016-02-03. PMID:25697672. |
interstrain differences of ionotropic glutamate receptor subunits in the hippocampus and induction of hippocampal sclerosis with pilocarpine in mice. |
2016-02-03 |
2023-08-13 |
mouse |
| Guo-Jiang Peng, Bi-Yun Shi, Jun-Sheng Tian, Shan Gao, Xue-Mei Qi. [1H NMR based metabonomics study on the antidepressant effect of genipin in rat hippocampus]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 49. issue 2. 2016-02-02. PMID:24761611. |
significant differences in the metabolic profile of rat hippocampus of the cums treated group and the control group were observed with metabolic effects of cums including decreasing in glycine and n-acetylaspartate, increasing in inositol, glutamate, lactate, glutamine, taurine and alanine. |
2016-02-02 |
2023-08-13 |
rat |
| E J Connors, M M Migliore, S L Pillsbury, A N Shaik, A C Kentne. Environmental enrichment models a naturalistic form of maternal separation and shapes the anxiety response patterns of offspring. Psychoneuroendocrinology. vol 52. 2016-01-29. PMID:25437120. |
serotonin, corticosterone, gaba, glutamate) in prefrontal cortex and hippocampus as a function of ee, communal nesting (cn) and standard care (sc). |
2016-01-29 |
2023-08-13 |
rat |
| Xiao-Yuan Mao, Yong-Gang Cao, Zhong Ji, Hong-Hao Zhou, Zhao-Qian Liu, Hong-Li Su. Topiramate protects against glutamate excitotoxicity via activating BDNF/TrkB-dependent ERK pathway in rodent hippocampal neurons. Progress in neuro-psychopharmacology & biological psychiatry. vol 60. 2016-01-22. PMID:25661849. |
topiramate protects against glutamate excitotoxicity via activating bdnf/trkb-dependent erk pathway in rodent hippocampal neurons. |
2016-01-22 |
2023-08-13 |
Not clear |
| Xiao-Yuan Mao, Yong-Gang Cao, Zhong Ji, Hong-Hao Zhou, Zhao-Qian Liu, Hong-Li Su. Topiramate protects against glutamate excitotoxicity via activating BDNF/TrkB-dependent ERK pathway in rodent hippocampal neurons. Progress in neuro-psychopharmacology & biological psychiatry. vol 60. 2016-01-22. PMID:25661849. |
our present work aimed to evaluate the protective effect of tpm against glutamate toxicity in hippocampal neurons and further figure out the potential molecular mechanisms. |
2016-01-22 |
2023-08-13 |
Not clear |
| Xiao-Yuan Mao, Yong-Gang Cao, Zhong Ji, Hong-Hao Zhou, Zhao-Qian Liu, Hong-Li Su. Topiramate protects against glutamate excitotoxicity via activating BDNF/TrkB-dependent ERK pathway in rodent hippocampal neurons. Progress in neuro-psychopharmacology & biological psychiatry. vol 60. 2016-01-22. PMID:25661849. |
our results demonstrated that tpm protected hippocampal neurons from glutamate toxicity. |
2016-01-22 |
2023-08-13 |
Not clear |
| Xiao-Yuan Mao, Yong-Gang Cao, Zhong Ji, Hong-Hao Zhou, Zhao-Qian Liu, Hong-Li Su. Topiramate protects against glutamate excitotoxicity via activating BDNF/TrkB-dependent ERK pathway in rodent hippocampal neurons. Progress in neuro-psychopharmacology & biological psychiatry. vol 60. 2016-01-22. PMID:25661849. |
in conclusion, these findings implicate that tpm exerts neuroprotective effects against glutamate excitotoxicity in hippocampal neurons and its protection may be modulated through bdnf/trkb-dependent erk pathway. |
2016-01-22 |
2023-08-13 |
Not clear |
| b' Andrea \\xc5\\xa0polcov\\xc3\\xa1, Barbora Mikul\\xc3\\xa1\\xc5\\xa1kov\\xc3\\xa1, Martina Holubov\\xc3\\xa1, Veronika Nagelov\\xc3\\xa1, Zdenko Pirnik, Jana Zemenov\\xc3\\xa1, Martin Haluz\\xc3\\xadk, Blanka \\xc5\\xbdelezn\\xc3\\xa1, Marie-Christine Galas, Lenka Malet\\xc3\\xadnsk\\xc3\\xa. Anorexigenic lipopeptides ameliorate central insulin signaling and attenuate tau phosphorylation in hippocampi of mice with monosodium glutamate-induced obesity. Journal of Alzheimer\'s disease : JAD. vol 45. issue 3. 2016-01-19. PMID:25624414.' |
we demonstrated that 6-month-old mice with monosodium glutamate (msg) obesity, which represent a model of obesity-induced pre-diabetes, had increased tau phosphorylation at ser396 and thr231 in the hippocampus compared with the controls, as determined by western blots. |
2016-01-19 |
2023-08-13 |
mouse |
| Fashui Hong, Lei Sheng, Yuguan Ze, Jie Hong, Yingjun Zhou, Ling Wang, Dong Liu, Xiaohong Yu, Bingqing Xu, Xiaoyang Zhao, Xiao Z. Suppression of neurite outgrowth of primary cultured hippocampal neurons is involved in impairment of glutamate metabolism and NMDA receptor function caused by nanoparticulate TiO2. Biomaterials. vol 53. 2016-01-19. PMID:25890708. |
suppression of neurite outgrowth of primary cultured hippocampal neurons is involved in impairment of glutamate metabolism and nmda receptor function caused by nanoparticulate tio2. |
2016-01-19 |
2023-08-13 |
rat |
| Fashui Hong, Lei Sheng, Yuguan Ze, Jie Hong, Yingjun Zhou, Ling Wang, Dong Liu, Xiaohong Yu, Bingqing Xu, Xiaoyang Zhao, Xiao Z. Suppression of neurite outgrowth of primary cultured hippocampal neurons is involved in impairment of glutamate metabolism and NMDA receptor function caused by nanoparticulate TiO2. Biomaterials. vol 53. 2016-01-19. PMID:25890708. |
in order to investigate the mechanism of neurotoxicity, rat primary cultured hippocampal neurons on the fourth day of culture were exposed to 5, 15, and 30 μg/ml nano-tio2 for 24 h, and nano-tio2 internalization, dendritic growth, glutamate metabolism, expression of n-methyl-d-aspartate (nmda) receptor subunits (nr1, nr2a and nr2b), calcium homeostasis, sodium current (ina) and potassium current (ik) were examined. |
2016-01-19 |
2023-08-13 |
rat |
| Fashui Hong, Lei Sheng, Yuguan Ze, Jie Hong, Yingjun Zhou, Ling Wang, Dong Liu, Xiaohong Yu, Bingqing Xu, Xiaoyang Zhao, Xiao Z. Suppression of neurite outgrowth of primary cultured hippocampal neurons is involved in impairment of glutamate metabolism and NMDA receptor function caused by nanoparticulate TiO2. Biomaterials. vol 53. 2016-01-19. PMID:25890708. |
taken together, these findings indicate that nano-tio2 inhibits neurite outgrowth of hippocampal neurons by interfering with glutamate metabolism and impairing nmda receptor function. |
2016-01-19 |
2023-08-13 |
rat |
| Marcus V Zanetti, Maria C Otaduy, Rafael T de Sousa, Wagner F Gattaz, Geraldo F Busatto, Claudia C Leite, Rodrigo Machado-Vieir. Bimodal effect of lithium plasma levels on hippocampal glutamate concentrations in bipolar II depression: a pilot study. The international journal of neuropsychopharmacology. vol 18. issue 6. 2016-01-12. PMID:25522399. |
bimodal effect of lithium plasma levels on hippocampal glutamate concentrations in bipolar ii depression: a pilot study. |
2016-01-12 |
2023-08-13 |
Not clear |
| Natalia S Rozas, John B Redell, Juan D Pita-Almenar, James Mckenna, Anthony N Moore, Michael J Gambello, Pramod K Das. Intrahippocampal glutamine administration inhibits mTORC1 signaling and impairs long-term memory. Learning & memory (Cold Spring Harbor, N.Y.). vol 22. issue 5. 2016-01-12. PMID:25878136. |
intracellular recordings in hippocampal slices showed that glutamine did not alter either excitatory or inhibitory synaptic activity, suggesting that the observed memory impairments may not result from conversion of glutamine to either glutamate or gaba. |
2016-01-12 |
2023-08-13 |
rat |
| Daniel J Whitcomb, Elek Molná. Is riluzole a new drug for Alzheimer's disease? Journal of neurochemistry. vol 135. issue 2. 2016-01-12. PMID:26451974. |
the authors employed a comprehensive analysis of possible restorative effects of the drug by examining glutamate levels in subregions of the hippocampus, expression of tau and its hyper-phosphorylated forms, and memory function using behavioral tests. |
2016-01-12 |
2023-08-13 |
mouse |
| Samantha L Scudder, Gentry N Patric. Synaptic structure and function are altered by the neddylation inhibitor MLN4924. Molecular and cellular neurosciences. vol 65. 2016-01-11. PMID:25701678. |
application of this drug to dissociated rat hippocampal neurons caused reductions in synaptic strength, surface glutamate receptor levels, dendritic spine width, and spine density, suggesting that neddylation is involved in the maintenance of synapses. |
2016-01-11 |
2023-08-13 |
rat |