| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Seyed Assad Karimi, Alireza Komaki, Iraj Salehi, Abdolrahman Sarihi, Siamak Shahid. Role of group II metabotropic glutamate receptors (mGluR2/3) blockade on long-term potentiation in the dentate gyrus region of hippocampus in rats fed with high-fat diet. Neurochemical research. vol 40. issue 4. 2016-04-05. PMID:25657067. |
high-fat diets (hfds) adversely influence hippocampal structure and function and induce changes in hippocampal glutamate metabolism and neurotransmission. |
2016-04-05 |
2023-08-13 |
rat |
| Xia Jiang, Gao-Shang Chai, Zhi-Hao Wang, Yu Hu, Xiao-Guang Li, Zhi-Wei Ma, Qun Wang, Jian-Zhi Wang, Gong-Ping Li. Spatial training preserves associative memory capacity with augmentation of dendrite ramification and spine generation in Tg2576 mice. Scientific reports. vol 5. 2016-04-05. PMID:25820815. |
in the molecular level, the mwm training remarkably activated calcium/calmodulin-dependent protein kinase ii (camkii) with elevation of glutamate ampa receptor glua1 subunit (glua1), postsynaptic density protein 93 (psd93) and postsynaptic density protein 95 (psd95) in the hippocampus. |
2016-04-05 |
2023-08-13 |
mouse |
| Shahid Ali Shah, Gwang Ho Yoon, Hyun-Ok Kim, Myeong Ok Ki. Vitamin C neuroprotection against dose-dependent glutamate-induced neurodegeneration in the postnatal brain. Neurochemical research. vol 40. issue 5. 2016-04-01. PMID:25701025. |
however, co-treatment of vitamin c (250 mg/kg) with glutamate decreased brain glutamate levels and reversed the changes induced by glutamate in the developing hippocampus. |
2016-04-01 |
2023-08-13 |
rat |
| André Ehrlich, Florian Schubert, Corinna Pehrs, Jürgen Gallina. Alterations of cerebral glutamate in the euthymic state of patients with bipolar disorder. Psychiatry research. vol 233. issue 2. 2016-03-29. PMID:26050195. |
proton magnetic resonance spectroscopy at 3t was used to determine glutamate concentrations in the anterior cingulate cortex (acc) and the hippocampus (hc) of euthymic outpatients with bp-i disorder and age- and sex-matched healthy controls. |
2016-03-29 |
2023-08-13 |
Not clear |
| Kate M Chitty, Jim Lagopoulos, Ian B Hickie, Daniel F Hermen. Hippocampal glutamatergic/NMDA receptor functioning in bipolar disorder: A study combining mismatch negativity and proton magnetic resonance spectroscopy. Psychiatry research. vol 233. issue 2. 2016-03-29. PMID:26070970. |
disturbances in the hippocampal glutamate (glu)/n-methyl-d-aspartate (nmda) system have been implicated in the pathophysiology of bipolar disorder (bd). |
2016-03-29 |
2023-08-13 |
human |
| Liqian Sun, Junling Gao, Manman Zhao, Jianzhong Cui, Youxiang Li, Xinjian Yang, Xiaobin Jing, Zhongxue W. A novel cognitive impairment mechanism that astrocytic p-connexin 43 promotes neuronic autophagy via activation of P2X7R and down-regulation of GLT-1 expression in the hippocampus following traumatic brain injury in rats. Behavioural brain research. vol 291. 2016-03-28. PMID:26031379. |
immunoblotting analysis showed that the expression of autophagy-related gene beclin-1 in the hippocampus post-tbi were decreased in response to treatment with cbx, the p2x7 receptor (p2x7r) antagonist oxidized atp (oxatp) or ceftriaxone (cef) which increased the expression and activity of the glutamate transporter (glt-1) in the central nervous system (cns). |
2016-03-28 |
2023-08-13 |
rat |
| Andras Kern, Maria Mavrikaki, Celine Ullrich, Rosie Albarran-Zeckler, Alicia Faruzzi Brantley, Roy G Smit. Hippocampal Dopamine/DRD1 Signaling Dependent on the Ghrelin Receptor. Cell. vol 163. issue 5. 2016-03-27. PMID:26590421. |
activation by a drd1 agonist produced non-canonical signal transduction via gαq-plc-ip3-ca(2+) at the expense of canonical drd1 gαs camp signaling to result in camkii activation, glutamate receptor exocytosis, synaptic reorganization, and expression of early markers of hippocampal synaptic plasticity. |
2016-03-27 |
2023-08-13 |
mouse |
| G Ojeda-Torres, L Williams, D E Featherstone, S A Shipp. Sample collection and amino acids analysis of extracellular fluid of mouse brain slices with low flow push-pull perfusion. The Analyst. vol 140. issue 19. 2016-03-25. PMID:26299259. |
glutamate was measured from the ca1 region of the hippocampus in slices taken from a cystine-glutamate transporter deletion mutant, xct(-/-), and the background strain c57bl/6j. |
2016-03-25 |
2023-08-13 |
mouse |
| Gemma McGregor, Yasaman Malekizadeh, Jenni Harve. Minireview: Food for thought: regulation of synaptic function by metabolic hormones. Molecular endocrinology (Baltimore, Md.). vol 29. issue 1. 2016-03-24. PMID:25470238. |
indeed, it has been demonstrated that both leptin and insulin markedly influence key cellular events that underlie hippocampal learning and memory including activity-dependent synaptic plasticity and the trafficking of glutamate receptors to and away from hippocampal synapses. |
2016-03-24 |
2023-08-13 |
Not clear |
| D H Bergin, Y Jing, H Zhang, P Li. A single intracerebroventricular Aβ25-35 infusion leads to prolonged alterations in arginine metabolism in the rat hippocampus and prefrontal cortex. Neuroscience. vol 298. 2016-03-21. PMID:25907447. |
the present study measured the levels of l-arginine and its nine downstream metabolites (l-citrulline, l-ornithine, agmatine, putrescine, spermidine, spermine, glutamate, gaba and glutamine) in the hippocampus and pfc at the time points of 42 and 97 days following a single bilateral i.c.v. |
2016-03-21 |
2023-08-13 |
rat |
| D H Bergin, Y Jing, H Zhang, P Li. A single intracerebroventricular Aβ25-35 infusion leads to prolonged alterations in arginine metabolism in the rat hippocampus and prefrontal cortex. Neuroscience. vol 298. 2016-03-21. PMID:25907447. |
at the 42-day time point, aβ25-35 resulted in decreased levels of glutamate, glutamine and spermine in the ca2/3 sub-region of the hippocampus. |
2016-03-21 |
2023-08-13 |
rat |
| Jie Zhang, Xin Fang, Yiyi Zhou, Xia Deng, Yi Lu, Jiao Li, Shujuan Li, Bo Wang, Renshi X. The Possible Damaged Mechanism and the Preventive Effect of Monosialotetrahexosylganglioside in a Rat Model of Cerebral Ischemia-Reperfusion Injury. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. vol 24. issue 7. 2016-03-10. PMID:25934141. |
therefore, our study aimed to investigate the possible pathogenesis and preventive approach of ciri through analyzing changes of aspartate (asp), glutamate (glu), mitochondrial calcium (mca), calmodulin (cam), and malondialdehyde (mda) contents and ultramicropathology in hippocampus and cerebral cortex of ischemic susceptible injured regions and the effect of monosialotetrahexosylganglioside (gm1) in the rat model of ciri. |
2016-03-10 |
2023-08-13 |
rat |
| Keiko Kanamor. Disinhibition reduces extracellular glutamine and elevates extracellular glutamate in rat hippocampus in vivo. Epilepsy research. vol 114. 2016-03-10. PMID:26088883. |
disinhibition reduces extracellular glutamine and elevates extracellular glutamate in rat hippocampus in vivo. |
2016-03-10 |
2023-08-13 |
rat |
| Cai Li, Qing Lu, Pengcheng Huang, Tianli Fu, Changjun Li, Lianjun Guo, Xulin X. Activity-dependent downregulation of M-Type (Kv7) K⁺ channels surface expression requires the activation of iGluRs/Ca²⁺/PKC signaling pathway in hippocampal neuron. Neuropharmacology. vol 95. 2016-03-08. PMID:25796298. |
in the present study, we found that treatment with glutamate rapidly caused a specific decrease in m-current as well as kv7 channel surface expression in primary cultured hippocampal neurons. |
2016-03-08 |
2023-08-13 |
Not clear |
| Katherine L Eales, Oleg Palygin, Thomas O'Loughlin, Seyed Rasooli-Nejad, Matthias Gaestel, Jürgen Müller, Dawn R Collins, Yuriy Pankratov, Sonia A L Corrê. The MK2/3 cascade regulates AMPAR trafficking and cognitive flexibility. Nature communications. vol 5. 2016-03-07. PMID:25134715. |
one form of ltd expressed in the hippocampus is initiated by the activation of the group 1 metabotropic glutamate receptors (mglurs). |
2016-03-07 |
2023-08-13 |
mouse |
| Shawn Zheng Kai Tan, Despina E Ganella, Alec Lindsay Ward Dick, Jhodie R Duncan, Emma Ong-Palsson, Ross A D Bathgate, Jee Hyun Kim, Andrew J Lawrenc. Spatial Learning Requires mGlu5 Signalling in the Dorsal Hippocampus. Neurochemical research. vol 40. issue 6. 2016-03-07. PMID:25957750. |
we examined the role of hippocampal metabotropic glutamate receptor 5 (mglu5) in spatial learning and memory. |
2016-03-07 |
2023-08-13 |
mouse |
| César E Santana-Gómez, David Alcántara-González, Hiram Luna-Munguía, Ivette Bañuelos-Cabrera, Víctor Magdaleno-Madrigal, Rodrigo Fernández-Mas, Walter Besio, Luisa Roch. Transcranial focal electrical stimulation reduces the convulsive expression and amino acid release in the hippocampus during pilocarpine-induced status epilepticus in rats. Epilepsy & behavior : E&B. vol 49. 2016-03-03. PMID:26006058. |
the aim of the present study was to evaluate the effects of transcranial focal electrical stimulation (tfs) on γ-aminobutyric acid (gaba) and glutamate release in the hippocampus under basal conditions and during pilocarpine-induced status epilepticus (se). |
2016-03-03 |
2023-08-13 |
rat |
| César E Santana-Gómez, David Alcántara-González, Hiram Luna-Munguía, Ivette Bañuelos-Cabrera, Víctor Magdaleno-Madrigal, Rodrigo Fernández-Mas, Walter Besio, Luisa Roch. Transcranial focal electrical stimulation reduces the convulsive expression and amino acid release in the hippocampus during pilocarpine-induced status epilepticus in rats. Epilepsy & behavior : E&B. vol 49. 2016-03-03. PMID:26006058. |
the first microdialysis experiment was designed to determine, under basal conditions, the effects of tfs (300 hz, 200 μs biphasic square pulses, for 30 min) on afterdischarge threshold (adt) and the release of gaba and glutamate in the hippocampus. |
2016-03-03 |
2023-08-13 |
rat |
| César E Santana-Gómez, David Alcántara-González, Hiram Luna-Munguía, Ivette Bañuelos-Cabrera, Víctor Magdaleno-Madrigal, Rodrigo Fernández-Mas, Walter Besio, Luisa Roch. Transcranial focal electrical stimulation reduces the convulsive expression and amino acid release in the hippocampus during pilocarpine-induced status epilepticus in rats. Epilepsy & behavior : E&B. vol 49. 2016-03-03. PMID:26006058. |
the extracellular levels of gaba and glutamate in the hippocampus remained at basal conditions. |
2016-03-03 |
2023-08-13 |
rat |
| N M Jadavji, F Wieske, U Dirnagl, C Winte. Methylenetetrahydrofolate reductase deficiency alters levels of glutamate and γ-aminobutyric acid in brain tissue. Molecular genetics and metabolism reports. vol 3. 2016-03-03. PMID:26937386. |
mthfr deficiency affected levels of both glutamate and γ-aminobutyric acid in within the cerebellum and hippocampus. |
2016-03-03 |
2023-08-13 |
mouse |