Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Javier Del Pino, María Teresa Frejo, María José Anadon Baselga, Paula Moyano, María Jesús Día. Impaired glutamatergic and GABAergic transmission by amitraz in primary hippocampal cells. Neurotoxicology and teratology. vol 50. 2016-04-25. PMID:26141220. |
to confirm if amitraz disrupts glutamatergic/gabaergic transmission by these mechanisms, we evaluated, in primary hippocampal neurons, the effect of amitraz (0.01 μm to 100 μm) with or without the α2 adrenergic antagonist idazoxan (1 μm) and/or the h1 receptor agonist n-methylhistaprodifen (30 μm) co-treatment on 4-aminobutyrate aminotransferase, glutamate decarboxylase 65 (gad 65), succinate-semialdehyde dehydrogenase and glutaminase gene expression and on glutamate and gaba levels after 24h treatment. |
2016-04-25 |
2023-08-13 |
Not clear |
Daniel F Hermens, Kate M Chitty, Rico Sc Lee, Ashleigh Tickell, Paul S Haber, Sharon L Naismith, Ian B Hickie, Jim Lagopoulo. Hippocampal glutamate is increased and associated with risky drinking in young adults with major depression. Journal of affective disorders. vol 186. 2016-04-25. PMID:26233319. |
hippocampal glutamate is increased and associated with risky drinking in young adults with major depression. |
2016-04-25 |
2023-08-13 |
Not clear |
Daniel F Hermens, Kate M Chitty, Rico Sc Lee, Ashleigh Tickell, Paul S Haber, Sharon L Naismith, Ian B Hickie, Jim Lagopoulo. Hippocampal glutamate is increased and associated with risky drinking in young adults with major depression. Journal of affective disorders. vol 186. 2016-04-25. PMID:26233319. |
the hippocampus and the glutamate system have been implicated in the pathophysiology of alcoholism and depression. |
2016-04-25 |
2023-08-13 |
Not clear |
Daniel F Hermens, Kate M Chitty, Rico Sc Lee, Ashleigh Tickell, Paul S Haber, Sharon L Naismith, Ian B Hickie, Jim Lagopoulo. Hippocampal glutamate is increased and associated with risky drinking in young adults with major depression. Journal of affective disorders. vol 186. 2016-04-25. PMID:26233319. |
this study aimed to determine whether risky drinking is associated with glutamate levels recorded within the hippocampus of young adults with major depression. |
2016-04-25 |
2023-08-13 |
Not clear |
Xuechao Hao, Xianlin Zhu, Ping Li, Feng Lv, Su Mi. NMDA receptor antagonist enhances antidepressant efficacy and alleviates learning-memory function impairment induced by electroconvulsive shock with regulating glutamate receptors expression in hippocampus. Journal of affective disorders. vol 190. 2016-04-22. PMID:26625094. |
nmda receptor antagonist enhances antidepressant efficacy and alleviates learning-memory function impairment induced by electroconvulsive shock with regulating glutamate receptors expression in hippocampus. |
2016-04-22 |
2023-08-13 |
Not clear |
Giovana Brolese, Paula Lunardi, Daniela F de Souza, Fernanda M Lopes, Marina C Leite, Carlos-Alberto Gonçalve. Pre- and postnatal exposure to moderate levels of ethanol can have long-lasting effects on hippocampal glutamate uptake in adolescent offspring. PloS one. vol 10. issue 5. 2016-04-19. PMID:25978644. |
pre- and postnatal exposure to moderate levels of ethanol can have long-lasting effects on hippocampal glutamate uptake in adolescent offspring. |
2016-04-19 |
2023-08-13 |
rat |
M Soukupova, A Binaschi, C Falcicchia, E Palma, P Roncon, S Zucchini, M Simonat. Increased extracellular levels of glutamate in the hippocampus of chronically epileptic rats. Neuroscience. vol 301. 2016-04-18. PMID:26073699. |
increased extracellular levels of glutamate in the hippocampus of chronically epileptic rats. |
2016-04-18 |
2023-08-13 |
rat |
M Soukupova, A Binaschi, C Falcicchia, E Palma, P Roncon, S Zucchini, M Simonat. Increased extracellular levels of glutamate in the hippocampus of chronically epileptic rats. Neuroscience. vol 301. 2016-04-18. PMID:26073699. |
the aim of this study was to systematically evaluate the relationship between seizure activity and changes in hippocampal glutamate and aspartate extracellular levels under basal and high k(+)-evoked conditions, at various time-points in the natural history of experimental temporal lobe epilepsy, using in vivo microdialysis. |
2016-04-18 |
2023-08-13 |
rat |
M Soukupova, A Binaschi, C Falcicchia, E Palma, P Roncon, S Zucchini, M Simonat. Increased extracellular levels of glutamate in the hippocampus of chronically epileptic rats. Neuroscience. vol 301. 2016-04-18. PMID:26073699. |
hippocampal extracellular glutamate and aspartate levels were evaluated: 24h after pilocarpine-induced status epilepticus (se); during the latency period preceding spontaneous seizures; immediately after the first spontaneous seizure; in the chronic (epileptic) period. |
2016-04-18 |
2023-08-13 |
rat |
Carla Nasca, Danielle Zelli, Benedetta Bigio, Sonia Piccinin, Sergio Scaccianoce, Robert Nisticò, Bruce S McEwe. Stress dynamically regulates behavior and glutamatergic gene expression in hippocampus by opening a window of epigenetic plasticity. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 48. 2016-04-15. PMID:26627246. |
they reveal a key role for epigenetic up- and down-regulation of the putative presynaptic type 2 metabotropic glutamate (mglu2) receptors and the postsynaptic nr1/nmda receptors in the hippocampus and particularly in the dentate gyrus (dg), a region of active neurogenesis and a target of antidepressant treatment. |
2016-04-15 |
2023-08-13 |
mouse |
Carla Álvarez-Ferradas, Juan Carlos Morales, Mario Wellmann, Francisco Nualart, Manuel Roncagliolo, Marco Fuenzalida, Christian Bonansc. Enhanced astroglial Ca2+ signaling increases excitatory synaptic strength in the epileptic brain. Glia. vol 63. issue 9. 2016-04-13. PMID:25980474. |
our findings show that elevated ca(2+)-dependent glutamate gliotransmission from hyperexcitable astrocytes up-regulates excitatory neurotransmission in epileptic hippocampus, suggesting that gliotransmission should be considered as a novel functional key in a broad spectrum of neuropathological conditions. |
2016-04-13 |
2023-08-13 |
rat |
Nilmini Viswaprakash, Thirumalini Vaithianathan, Ajitan Viswaprakash, Robert Judd, Kodeeswaran Parameshwaran, Vishnu Suppiramania. Insulin treatment restores glutamate (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptor function in the hippocampus of diabetic rats. Journal of neuroscience research. vol 93. issue 9. 2016-04-12. PMID:25807926. |
insulin treatment restores glutamate (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptor function in the hippocampus of diabetic rats. |
2016-04-12 |
2023-08-13 |
rat |
Nilmini Viswaprakash, Thirumalini Vaithianathan, Ajitan Viswaprakash, Robert Judd, Kodeeswaran Parameshwaran, Vishnu Suppiramania. Insulin treatment restores glutamate (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptor function in the hippocampus of diabetic rats. Journal of neuroscience research. vol 93. issue 9. 2016-04-12. PMID:25807926. |
cognitive processing, particularly memory acquisition, depends on the regulated enhancement of expression and function of glutamate receptor subtypes in the hippocampus. |
2016-04-12 |
2023-08-13 |
rat |
Basel A Abdel-Wahab, Ibrahim A Shaikh, Masood M Khateeb, Shafiuddin M Habee. Omega 3 polyunsaturated fatty acids enhance the protective effect of levetiracetam against seizures, cognitive impairment and hippocampal oxidative DNA damage in young kindled rats. Pharmacology, biochemistry, and behavior. vol 135. 2016-04-12. PMID:26044965. |
moreover, the increase in hippocampal glutamate, malondialdehyde and 8-hydroxy-2-deoxyguanosine (8-ohdg) levels, as well as the decrease in reduced glutathione (gsh) levels and gsh-peroxidase and superoxide dismutase activities induced by ptz kindling, significantly decreased. |
2016-04-12 |
2023-08-13 |
rat |
Mario Allegra, Fabio Carletti, Giuditta Gambino, Marco Tutone, Alessandro Attanzio, Luisa Tesoriere, Giuseppe Ferraro, Pierangelo Sardo, Anna Maria Almerico, Maria Antonia Livre. Indicaxanthin from Opuntia ficus-indica Crosses the Blood-Brain Barrier and Modulates Neuronal Bioelectric Activity in Rat Hippocampus at Dietary-Consistent Amounts. Journal of agricultural and food chemistry. vol 63. issue 33. 2016-04-12. PMID:26227670. |
a molecular target of indicaxanthin is suggested by in silico molecular modeling of indicaxanthin with n-methyl-d-aspartate receptor (nmdar), the most represented of the glutamate receptor family in hippocampus. |
2016-04-12 |
2023-08-13 |
rat |
Carlos M Matias, Jose C Dionísio, Peter Saggau, Maria Emilia Quinta-Ferreir. Activation of group II metabotropic glutamate receptors blocks zinc release from hippocampal mossy fibers. Biological research. vol 47. 2016-04-11. PMID:25723955. |
activation of group ii metabotropic glutamate receptors blocks zinc release from hippocampal mossy fibers. |
2016-04-11 |
2023-08-13 |
Not clear |
Awanish Mishra, Rajesh Kumar Goe. Comparative behavioral and neurochemical analysis of phenytoin and valproate treatment on epilepsy induced learning and memory deficit: Search for add on therapy. Metabolic brain disease. vol 30. issue 4. 2016-04-08. PMID:25613529. |
on day 20, after behavioral evaluations, animals were sacrificed to analyze glutamate, gaba, norepinephrine, dopamine, serotonin, total nitrite level and acetylcholinesterase level in cortex and hippocampus. |
2016-04-08 |
2023-08-13 |
Not clear |
Mohammad Nasehi, Elmira Sharaf-Dolgari, Mohaddeseh Ebrahimi-Ghiri, Mohammad-Reza Zarrindas. The hippocampal NMDA receptors may be involved in acquisition, but not expression of ACPA-induced place preference. Progress in neuro-psychopharmacology & biological psychiatry. vol 63. 2016-04-08. PMID:26072736. |
numerous studies have investigated the functional interactions between the endocannabinoid and glutamate systems in the hippocampus. |
2016-04-08 |
2023-08-13 |
mouse |
Seyed Assad Karimi, Alireza Komaki, Iraj Salehi, Abdolrahman Sarihi, Siamak Shahid. Role of group II metabotropic glutamate receptors (mGluR2/3) blockade on long-term potentiation in the dentate gyrus region of hippocampus in rats fed with high-fat diet. Neurochemical research. vol 40. issue 4. 2016-04-05. PMID:25657067. |
role of group ii metabotropic glutamate receptors (mglur2/3) blockade on long-term potentiation in the dentate gyrus region of hippocampus in rats fed with high-fat diet. |
2016-04-05 |
2023-08-13 |
rat |
Seyed Assad Karimi, Alireza Komaki, Iraj Salehi, Abdolrahman Sarihi, Siamak Shahid. Role of group II metabotropic glutamate receptors (mGluR2/3) blockade on long-term potentiation in the dentate gyrus region of hippocampus in rats fed with high-fat diet. Neurochemical research. vol 40. issue 4. 2016-04-05. PMID:25657067. |
in the hippocampus, metabotropic glutamate receptors (mglurs) are involved in various forms of synaptic plasticity. |
2016-04-05 |
2023-08-13 |
rat |