| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Idil Cavus, Gabriel A Widi, Robert B Duckrow, Hitten Zaveri, Jeremy T Kennard, John Krystal, Dennis D Spence. 50 Hz hippocampal stimulation in refractory epilepsy: Higher level of basal glutamate predicts greater release of glutamate. Epilepsia. vol 57. issue 2. 2016-08-01. PMID:26749134. |
we examined the effect of 50 hz stimulation on glutamate release and its relationship to interictal levels in the hippocampus of patients with epilepsy. |
2016-08-01 |
2023-08-13 |
Not clear |
| Mats Julius Stensrud, Carl Johan Sogn, Vidar Gunderse. Immunogold characteristics of VGLUT3-positive GABAergic nerve terminals suggest corelease of glutamate. The Journal of comparative neurology. vol 523. issue 18. 2016-07-20. PMID:26010578. |
now we provide novel electron microscopic data from the rat hippocampus suggesting that glutamate is enriched in inhibitory nerve terminals containing vglut3 compared to those lacking vglut3. |
2016-07-20 |
2023-08-13 |
rat |
| Mats Julius Stensrud, Carl Johan Sogn, Vidar Gunderse. Immunogold characteristics of VGLUT3-positive GABAergic nerve terminals suggest corelease of glutamate. The Journal of comparative neurology. vol 523. issue 18. 2016-07-20. PMID:26010578. |
the analyses suggest that glutamate is coreleased with gaba from hippocampal basket cell-synapses to act on nmda receptors. |
2016-07-20 |
2023-08-13 |
rat |
| Paula Valente-Silva, Cristina Lemos, Attila Köfalvi, Rodrigo A Cunha, John G Jone. Ketone bodies effectively compete with glucose for neuronal acetyl-CoA generation in rat hippocampal slices. NMR in biomedicine. vol 28. issue 9. 2016-07-19. PMID:26174755. |
hence, the contributions of exogenous 5.0 mm [1-(13)c]glucose and 1.0 mm [2-(13)c]lactate + 0.1 mm pyruvate (combined [2-(13)c]lactate + [2-(13)c]pyruvate) to acetyl-coa production were measured both without and with 5.0 mm [u-(13)c]3-hydroxybutyrate in superfused rat hippocampal slices by (13)c nmr non-steady-state isotopomer analysis of tissue glutamate and gaba. |
2016-07-19 |
2023-08-13 |
rat |
| Alan L Pehrson, Theepica Jeyarajah, Connie Sanche. Regional distribution of serotonergic receptors: a systems neuroscience perspective on the downstream effects of the multimodal-acting antidepressant vortioxetine on excitatory and inhibitory neurotransmission. CNS spectrums. vol 21. issue 2. 2016-07-19. PMID:26250622. |
previous work from this laboratory hypothesized that the multimodal antidepressant vortioxetine enhances cognitive function through a complex mechanism, using serotonergic (5-hydroxytryptamine, 5-ht) receptor actions to modulate gamma-butyric acid (gaba) and glutamate neurotransmission in key brain regions like the prefrontal cortex (pfc) and hippocampus. |
2016-07-19 |
2023-08-13 |
Not clear |
| J-T Li, Y-Y Zhao, H-L Wang, X-D Wang, Y-A Su, T-M S. Long-term effects of neonatal exposure to MK-801 on recognition memory and excitatory-inhibitory balance in rat hippocampus. Neuroscience. vol 308. 2016-07-19. PMID:26349007. |
the parvalbumin-positive (pv+) γ-aminobutyric acid (gaba)-ergic interneurons and presynaptic markers for excitatory and inhibitory neurons, vesicular glutamate transporter-1 (vglut1) and vesicular gaba transporter (vgat) were examined in the hippocampus to reflect the e/i balance. |
2016-07-19 |
2023-08-13 |
rat |
| María Mercedes Odeon, Marcela Andreu, Laura Yamauchi, Mauricio Grosman, Gabriela Beatriz Acost. Chronic postnatal stress induces voluntary alcohol intake and modifies glutamate transporters in adolescent rats. Stress (Amsterdam, Netherlands). vol 18. issue 4. 2016-07-13. PMID:26037264. |
cps: (1) increased voluntary ethanol intake, (2) did not affect body weight gain or produce signs of toxicity with alcohol exposure, (3) increased glutamate uptake by hippocampal synaptosomes in vitro and (4) reduced protein levels (western measurements) in hippocampus and frontal cortex of glial glutamate transporter-1 (glt-1) and excitatory amino-acid transporter-3 (eaat-3) but increased glutamate aspartate transporter (glast) levels. |
2016-07-13 |
2023-08-13 |
rat |
| Igor Nenadic, Raka Maitra, Soumyajit Basu, Maren Dietzek, Nils Schönfeld, Carsten Lorenz, Alexander Gussew, G Paul Amminger, Patrick McGorry, Jürgen R Reichenbach, Heinrich Sauer, Christian Gaser, Stefan Smesn. Associations of hippocampal metabolism and regional brain grey matter in neuroleptic-naïve ultra-high-risk subjects and first-episode schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 10. 2016-07-12. PMID:26088723. |
we applied both (1)h mrs (proton magnetic resonance spectroscopy) at 3tesla and voxel-based morphometry (vbm) of high-resolution brain structural images in order to study the association of the metabolites glutamate (glu) and n-acetyl-aspartate (naa) in the hippocampus with whole-brain morphometry in 31 persons at ultra-high-risk for psychosis (uhr), 18 first-episode schizophrenia patients (sz), and 42 healthy controls (all subjects being neuroleptic-naïve). |
2016-07-12 |
2023-08-13 |
human |
| Igor Nenadic, Raka Maitra, Soumyajit Basu, Maren Dietzek, Nils Schönfeld, Carsten Lorenz, Alexander Gussew, G Paul Amminger, Patrick McGorry, Jürgen R Reichenbach, Heinrich Sauer, Christian Gaser, Stefan Smesn. Associations of hippocampal metabolism and regional brain grey matter in neuroleptic-naïve ultra-high-risk subjects and first-episode schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 10. 2016-07-12. PMID:26088723. |
significantly diverging associations emerged for uhr subjects hippocampal glutamate showed positive correlation with the left superior frontal cortex, not seen in sz or controls, while in first-episode schizophrenia patients a negative correlation was significant between glutamate and a left prefrontal area. |
2016-07-12 |
2023-08-13 |
human |
| Chava Zuckerman, Elinor Blumkin, Osnat Melamed, Hava M Gola. Glutamatergic synapse protein composition of wild-type mice is sensitive to in utero MTHFR genotype and the timing of neonatal vigabatrin exposure. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 10. 2016-07-12. PMID:26235956. |
here we show that in utero mthfr deficiency is sufficient to alter the levels of glutamate receptor subunits glur1, glur2, and nr2b in the cerebral cortex and hippocampus of adult offspring with a wt genotype. |
2016-07-12 |
2023-08-13 |
mouse |
| Lei Zheng, Xiaoda Wu, Xiao Dong, Xinli Ding, Cunfeng Son. Effects of Chronic Alcohol Exposure on the Modulation of Ischemia-Induced Glutamate Release via Cannabinoid Receptors in the Dorsal Hippocampus. Alcoholism, clinical and experimental research. vol 39. issue 10. 2016-07-08. PMID:26343919. |
effects of chronic alcohol exposure on the modulation of ischemia-induced glutamate release via cannabinoid receptors in the dorsal hippocampus. |
2016-07-08 |
2023-08-13 |
Not clear |
| Haruki Fujisawa, Yoshihisa Sugimura, Hiroshi Takagi, Hiroyuki Mizoguchi, Hideyuki Takeuchi, Hisakazu Izumida, Kohtaro Nakashima, Hiroshi Ochiai, Seiji Takeuchi, Atsushi Kiyota, Kazuya Fukumoto, Shintaro Iwama, Yoshiko Takagishi, Yoshitaka Hayashi, Hiroshi Arima, Yukio Komatsu, Yoshiharu Murata, Yutaka Ois. Chronic Hyponatremia Causes Neurologic and Psychologic Impairments. Journal of the American Society of Nephrology : JASN. vol 27. issue 3. 2016-07-08. PMID:26376860. |
in vivo microdialysis revealed an elevated extracellular glutamate concentration in the hippocampus of chronically hyponatremic rats. |
2016-07-08 |
2023-08-13 |
rat |
| Marta Motolese, Federica Mastroiacovo, Milena Cannella, Domenico Bucci, Anderson Gaglione, Barbara Riozzi, Robert Lütjens, Sonia M Poli, Sylvain Celanire, Valeria Bruno, Giuseppe Battaglia, Ferdinando Nicolett. Targeting type-2 metabotropic glutamate receptors to protect vulnerable hippocampal neurons against ischemic damage. Molecular brain. vol 8. issue 1. 2016-07-06. PMID:26496940. |
targeting type-2 metabotropic glutamate receptors to protect vulnerable hippocampal neurons against ischemic damage. |
2016-07-06 |
2023-08-13 |
rat |
| Vojtech Vyklicky, Tereza Smejkalova, Barbora Krausova, Ales Balik, Miloslav Korinek, Jirina Borovska, Martin Horak, Marketa Chvojkova, Lenka Kleteckova, Karel Vales, Jiri Cerny, Michaela Nekardova, Hana Chodounska, Eva Kudova, Ladislav Vyklick. Preferential Inhibition of Tonically over Phasically Activated NMDA Receptors by Pregnane Derivatives. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 7. 2016-06-29. PMID:26888927. |
here, using heterologously expressed glun1/glun2a and glun1/glun2b receptors and rat autaptic hippocampal microisland cultures, we show that pregnanolone sulfate inhibits nmdar currents induced by a prolonged glutamate application with a higher potency than the nmdar component of epscs. |
2016-06-29 |
2023-08-13 |
rat |
| Kevin F H Lee, Cary Soares, Jean-Philippe Thivierge, Jean-Claude Béïqu. Correlated Synaptic Inputs Drive Dendritic Calcium Amplification and Cooperative Plasticity during Clustered Synapse Development. Neuron. vol 89. issue 4. 2016-06-28. PMID:26853305. |
using whole-cell electrophysiology, two-photon calcium imaging, and glutamate uncaging in hippocampal slices, we discovered a functional coupling between nmda receptor activation and ryanodine-sensitive intracellular calcium release that dominates the spatiotemporal dynamics of activity-dependent calcium signals during synaptogenesis. |
2016-06-28 |
2023-08-13 |
Not clear |
| Shi-Bing Wong, Sin-Jhong Cheng, Wei-Chen Hung, Wang-Tso Lee, Ming-Yuan Mi. Rosiglitazone Suppresses In Vitro Seizures in Hippocampal Slice by Inhibiting Presynaptic Glutamate Release in a Model of Temporal Lobe Epilepsy. PloS one. vol 10. issue 12. 2016-06-27. PMID:26659605. |
rosiglitazone suppresses in vitro seizures in hippocampal slice by inhibiting presynaptic glutamate release in a model of temporal lobe epilepsy. |
2016-06-27 |
2023-08-13 |
Not clear |
| Xiao-Xue Zhang, Xiao-Chun Min, Xu-Lin Xu, Min Zheng, Lian-Jun Gu. ZD7288, a selective hyperpolarization-activated cyclic nucleotide-gated channel blocker, inhibits hippocampal synaptic plasticity. Neural regeneration research. vol 11. issue 5. 2016-06-23. PMID:27335562. |
we measured glutamate content in the hippocampus and in cultured hippocampal neurons using high performance liquid chromatography, and determined intracellular ca(2+) concentration [ca(2+)]i) using fura-2. |
2016-06-23 |
2023-08-13 |
rat |
| Xiao-Xue Zhang, Xiao-Chun Min, Xu-Lin Xu, Min Zheng, Lian-Jun Gu. ZD7288, a selective hyperpolarization-activated cyclic nucleotide-gated channel blocker, inhibits hippocampal synaptic plasticity. Neural regeneration research. vol 11. issue 5. 2016-06-23. PMID:27335562. |
zd7288 also decreased glutamate release in hippocampal tissue and in cultured hippocampal neurons. |
2016-06-23 |
2023-08-13 |
rat |
| Xiao-Xue Zhang, Xiao-Chun Min, Xu-Lin Xu, Min Zheng, Lian-Jun Gu. ZD7288, a selective hyperpolarization-activated cyclic nucleotide-gated channel blocker, inhibits hippocampal synaptic plasticity. Neural regeneration research. vol 11. issue 5. 2016-06-23. PMID:27335562. |
our results suggest that zd7288 inhibits hippocampal synaptic plasticity both glutamate release and resultant [ca(2+)]i increases in rat hippocampal neurons. |
2016-06-23 |
2023-08-13 |
rat |
| Hui Wang, Alvaro O Ardiles, Sunggu Yang, Trinh Tran, Rafael Posada-Duque, Gonzalo Valdivia, Min Baek, Yang-An Chuang, Adrian G Palacios, Michela Gallagher, Paul Worley, Alfredo Kirkwoo. Metabotropic Glutamate Receptors Induce a Form of LTP Controlled by Translation and Arc Signaling in the Hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 5. 2016-06-22. PMID:26843652. |
metabotropic glutamate receptors induce a form of ltp controlled by translation and arc signaling in the hippocampus. |
2016-06-22 |
2023-08-13 |
mouse |