| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jérôme Mairesse, Eleonora Gatta, Marie-Line Reynaert, Jordan Marrocco, Sara Morley-Fletcher, Marion Soichot, Lucie Deruyter, Gilles Van Camp, Hammou Bouwalerh, Francesca Fagioli, Anna Pittaluga, Delphine Allorge, Ferdinando Nicoletti, Stefania Maccar. Activation of presynaptic oxytocin receptors enhances glutamate release in the ventral hippocampus of prenatally restraint stressed rats. Psychoneuroendocrinology. vol 62. 2016-08-24. PMID:26231445. |
adult prs rats exhibit an anxious/depressive-like phenotype associated with an abnormal glucocorticoid feedback regulation of the hypothalamus-pituitary-adrenal (hpa) axis, and, remarkably, with a reduced depolarization-evoked glutamate release in the ventral hippocampus. |
2016-08-24 |
2023-08-13 |
rat |
| Jérôme Mairesse, Eleonora Gatta, Marie-Line Reynaert, Jordan Marrocco, Sara Morley-Fletcher, Marion Soichot, Lucie Deruyter, Gilles Van Camp, Hammou Bouwalerh, Francesca Fagioli, Anna Pittaluga, Delphine Allorge, Ferdinando Nicoletti, Stefania Maccar. Activation of presynaptic oxytocin receptors enhances glutamate release in the ventral hippocampus of prenatally restraint stressed rats. Psychoneuroendocrinology. vol 62. 2016-08-24. PMID:26231445. |
chronic systemic treatment with carbetocin (1mg/kg, i.p., once a day for 2-3 weeks) in prs rats corrected the defect in glutamate release, anxiety- and depressive-like behavior, and abnormalities in social behavior, in the hpa response to stress, and in the expression of stress-related genes in the hippocampus and amygdala. |
2016-08-24 |
2023-08-13 |
rat |
| Pedro H Gobira, Luciano R Vilela, Bruno D C Gonçalves, Rebeca P M Santos, Antonio C de Oliveira, Luciene B Vieira, Daniele C Aguiar, José A Crippa, Fabricio A Moreir. Cannabidiol, a Cannabis sativa constituent, inhibits cocaine-induced seizures in mice: Possible role of the mTOR pathway and reduction in glutamate release. Neurotoxicology. vol 50. 2016-08-24. PMID:26283212. |
synaptosome studies with the hippocampus of drug-treated animals revealed that cocaine increases glutamate release, whereas cbd induces the opposite effect. |
2016-08-24 |
2023-08-13 |
mouse |
| Chia Ying Chang, Tzu Yu Lin, Cheng Wei Lu, Shu Kuei Huang, Ying Chou Wang, Shang Shing Peter Chou, Su Jane Wan. Hesperidin inhibits glutamate release and exerts neuroprotection against excitotoxicity induced by kainic acid in the hippocampus of rats. Neurotoxicology. vol 50. 2016-08-24. PMID:26342684. |
hesperidin inhibits glutamate release and exerts neuroprotection against excitotoxicity induced by kainic acid in the hippocampus of rats. |
2016-08-24 |
2023-08-13 |
rat |
| Chia Ying Chang, Tzu Yu Lin, Cheng Wei Lu, Shu Kuei Huang, Ying Chou Wang, Shang Shing Peter Chou, Su Jane Wan. Hesperidin inhibits glutamate release and exerts neuroprotection against excitotoxicity induced by kainic acid in the hippocampus of rats. Neurotoxicology. vol 50. 2016-08-24. PMID:26342684. |
given the involvement of glutamate neurotoxicity in the pathogenesis of neurodegenerative disorders, this study was conducted to evaluate the potential role of hesperidin in glutamate release and glutamate neurotoxicity in the hippocampus of rats. |
2016-08-24 |
2023-08-13 |
rat |
| Chia Ying Chang, Tzu Yu Lin, Cheng Wei Lu, Shu Kuei Huang, Ying Chou Wang, Shang Shing Peter Chou, Su Jane Wan. Hesperidin inhibits glutamate release and exerts neuroprotection against excitotoxicity induced by kainic acid in the hippocampus of rats. Neurotoxicology. vol 50. 2016-08-24. PMID:26342684. |
in rat hippocampal nerve terminals (synaptosomes), hesperidin inhibited the release of glutamate and elevation of cytosolic free ca(2+) concentration evoked by 4-aminopyridine (4-ap), but did not alter 4-ap-mediated depolarization. |
2016-08-24 |
2023-08-13 |
rat |
| Chia Ying Chang, Tzu Yu Lin, Cheng Wei Lu, Shu Kuei Huang, Ying Chou Wang, Shang Shing Peter Chou, Su Jane Wan. Hesperidin inhibits glutamate release and exerts neuroprotection against excitotoxicity induced by kainic acid in the hippocampus of rats. Neurotoxicology. vol 50. 2016-08-24. PMID:26342684. |
the inhibitory effect of hesperidin on evoked glutamate release was prevented by chelating the extracellular ca(2+) ions and blocking the activity of cav2.2 (n-type) and cav2.1 (p/q-type) channels or protein kinase c. in hippocampal slice preparations, whole-cell patch clamp experiments showed that hesperidin reduced the frequency of spontaneous excitatory postsynaptic currents without affecting their amplitude, indicating the involvement of a presynaptic mechanism. |
2016-08-24 |
2023-08-13 |
rat |
| Chia Ying Chang, Tzu Yu Lin, Cheng Wei Lu, Shu Kuei Huang, Ying Chou Wang, Shang Shing Peter Chou, Su Jane Wan. Hesperidin inhibits glutamate release and exerts neuroprotection against excitotoxicity induced by kainic acid in the hippocampus of rats. Neurotoxicology. vol 50. 2016-08-24. PMID:26342684. |
these results demonstrate that hesperidin inhibits evoked glutamate release in vitro and attenuates in vivo ka-induced neuronal death in the hippocampus. |
2016-08-24 |
2023-08-13 |
rat |
| C Thetford Smothers, Karen K Szumlinski, Paul F Worley, John J Woodwar. Altered NMDA receptor function in primary cultures of hippocampal neurons from mice lacking the Homer2 gene. Synapse (New York, N.Y.). vol 70. issue 1. 2016-08-18. PMID:26426435. |
in this study, the function and ethanol sensitivity of glutamate receptors in cultured hippocampal neurons from wild-type (wt) and homer2 knock-out (ko) mice were examined at 7 and 14 days in vitro (div) using standard whole-cell voltage-clamp electrophysiology. |
2016-08-18 |
2023-08-13 |
mouse |
| Xueyan Zhou, Qiuxiang Zhu, Xiaowen Han, Renguo Chen, Yaowu Liu, Hongbin Fan, Xiaoxing Yi. Quantitative-profiling of neurotransmitter abnormalities in the disease progression of experimental diabetic encephalopathy rat. Canadian journal of physiology and pharmacology. vol 93. issue 11. 2016-08-18. PMID:26426748. |
in contrast, the glutamate (glu) levels were decreased in csf and the hippocampus, but unaffected in the serum and cortex of stz-treated rats. |
2016-08-18 |
2023-08-13 |
rat |
| Gustavo Henrique Souza Rezende, Patrícia Alves Maia Guidine, Daniel de Castro Medeiros, Tasso Moraes-Santos, Luiz Eugênio Mello, Márcio Flávio Dutra Morae. Protein-caloric dietary restriction inhibits mossy fiber sprouting in the pilocarpine model of TLE without significantly altering seizure phenotype. Epilepsy research. vol 117. 2016-08-18. PMID:26432758. |
on the 120th day, electroencephalography (eeg) was recorded and rats were sacrificed to measure proteins and glutamate release from hippocampus. |
2016-08-18 |
2023-08-13 |
rat |
| Gustavo Henrique Souza Rezende, Patrícia Alves Maia Guidine, Daniel de Castro Medeiros, Tasso Moraes-Santos, Luiz Eugênio Mello, Márcio Flávio Dutra Morae. Protein-caloric dietary restriction inhibits mossy fiber sprouting in the pilocarpine model of TLE without significantly altering seizure phenotype. Epilepsy research. vol 117. 2016-08-18. PMID:26432758. |
however, pilo promoted more k(+)-stimulated glutamate release in the hippocampus slices from wn animals when compared to the un group. |
2016-08-18 |
2023-08-13 |
rat |
| Masaki Kakeyam. [Development of Higher Brain Function Tests in Rodents and Its Application to Neurotoxicity Assessment of Environmental Chemicals]. Nihon eiseigaku zasshi. Japanese journal of hygiene. vol 70. issue 2. 2016-08-17. PMID:25994343. |
we first found changes in the mrna expression levels of glutamate nmda receptor subunits that have critical roles in learning and memory function in the neocortex and hippocampus. |
2016-08-17 |
2023-08-13 |
mouse |
| Miao-Kun Sun, Jarin Hongpaisan, Daniel L Alko. Rescue of Synaptic Phenotypes and Spatial Memory in Young Fragile X Mice. The Journal of pharmacology and experimental therapeutics. vol 357. issue 2. 2016-08-16. PMID:26941170. |
the therapeutic effects were achieved without downregulation of metabotropic glutamate receptor (mglur) 5 in the hippocampus and are more dramatic than those of a late-onset treatment in adult fragile x mice. |
2016-08-16 |
2023-08-13 |
mouse |
| G B Christiansen, B Harbak, S E Hede, A H Gouliaev, L Olsen, K Frydenvang, J Egebjerg, J S Kastrup, M M Hol. A novel dualistic profile of an allosteric AMPA receptor modulator identified through studies on recombinant receptors, mouse hippocampal synapses and crystal structures. Neuroscience. vol 310. 2016-08-15. PMID:26450748. |
furthermore, when applied to acutely isolated mouse brain slices, ns1376 reduced the field excitatory postsynaptic potentials (fepsps) in the hippocampus to 51.6 ± 4.3% of baseline, likely as a consequence of reduced glutamate potency. |
2016-08-15 |
2023-08-13 |
mouse |
| Wei Li, Xin Xu, Lucas Pozzo-Mille. Excitatory synapses are stronger in the hippocampus of Rett syndrome mice due to altered synaptic trafficking of AMPA-type glutamate receptors. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 11. 2016-08-12. PMID:26929363. |
excitatory synapses are stronger in the hippocampus of rett syndrome mice due to altered synaptic trafficking of ampa-type glutamate receptors. |
2016-08-12 |
2023-08-13 |
mouse |
| A Aksoy-Aksel, D Manahan-Vaugha. Synaptic strength at the temporoammonic input to the hippocampal CA1 region in vivo is regulated by NMDA receptors, metabotropic glutamate receptors and voltage-gated calcium channels. Neuroscience. vol 309. 2016-08-09. PMID:25791230. |
as group ii metabotropic glutamate (mglu) receptors are densely localized on presynaptic terminals of the perforant path, and are important for certain forms of hippocampal synaptic plasticity, we also explored whether group ii mglu receptors affect ltp at the pp-ca1 synapse and/or regulate basal synaptic transmission at this synapse in vivo. |
2016-08-09 |
2023-08-13 |
rat |
| J C Kreutzmann, R Havekes, T Abel, P Meerl. Sleep deprivation and hippocampal vulnerability: changes in neuronal plasticity, neurogenesis and cognitive function. Neuroscience. vol 309. 2016-08-09. PMID:25937398. |
although the molecular mechanisms underlying sleep and memory formation remain to be investigated, available evidence suggests that sd may impair hippocampal neuronal plasticity and memory processes by attenuating intracellular cyclic adenosine monophosphate (camp)-protein kinase a (pka) signaling which may lead to alterations in camp response element binding protein (creb)-mediated gene transcription, neurotrophic signaling, and glutamate receptor expression. |
2016-08-09 |
2023-08-13 |
Not clear |
| Idil Cavus, Gabriel A Widi, Robert B Duckrow, Hitten Zaveri, Jeremy T Kennard, John Krystal, Dennis D Spence. 50 Hz hippocampal stimulation in refractory epilepsy: Higher level of basal glutamate predicts greater release of glutamate. Epilepsia. vol 57. issue 2. 2016-08-01. PMID:26749134. |
50 hz hippocampal stimulation in refractory epilepsy: higher level of basal glutamate predicts greater release of glutamate. |
2016-08-01 |
2023-08-13 |
Not clear |
| Idil Cavus, Gabriel A Widi, Robert B Duckrow, Hitten Zaveri, Jeremy T Kennard, John Krystal, Dennis D Spence. 50 Hz hippocampal stimulation in refractory epilepsy: Higher level of basal glutamate predicts greater release of glutamate. Epilepsia. vol 57. issue 2. 2016-08-01. PMID:26749134. |
glutamate is elevated at baseline in the epileptogenic hippocampus of patients with refractory epilepsy, and increases during spontaneous seizures. |
2016-08-01 |
2023-08-13 |
Not clear |