Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
T A Antipova, S V Nikolaev, P U Ostrovskaya, T A Gudasheva, S B Seredeni. Dipeptide Piracetam Analogue Noopept Improves Viability of Hippocampal HT-22 Neurons in the Glutamate Toxicity Model. Bulletin of experimental biology and medicine. vol 161. issue 1. 2017-03-08. PMID:27265136. |
dipeptide piracetam analogue noopept improves viability of hippocampal ht-22 neurons in the glutamate toxicity model. |
2017-03-08 |
2023-08-13 |
mouse |
Mikhail Strokin, Georg Reise. Mitochondrial Ca(2+) Processing by a Unit of Mitochondrial Ca(2+) Uniporter and Na(+)/Ca(2+) Exchanger Supports the Neuronal Ca(2+) Influx via Activated Glutamate Receptors. Neurochemical research. vol 41. issue 6. 2017-03-06. PMID:26842930. |
the current study demonstrates that in hippocampal neurons mitochondrial ca(2+) processing supports ca(2+) influx via ionotropic glutamate (glu) receptors. |
2017-03-06 |
2023-08-13 |
Not clear |
Patrícia Nardin, Caroline Zanotto, Fernanda Hansen, Cristiane Batassini, Manuela Sangalli Gasparin, Patrícia Sesterheim, Carlos-Alberto Gonçalve. Peripheral Levels of AGEs and Astrocyte Alterations in the Hippocampus of STZ-Diabetic Rats. Neurochemical research. vol 41. issue 8. 2017-03-03. PMID:27084774. |
herein, we investigate specific astrocyte changes in the rat hippocampus in a model of dm induced by stz, particularly looking at glial fibrillary acidic protein (gfap), s100b protein and glutamate uptake, as well as the content of advanced glycated end products (ages) in serum and cerebrospinal fluid (csf), as a consequence of elevated hyperglycemia and the content of receptor for ages in the hippocampus. |
2017-03-03 |
2023-08-13 |
rat |
Marta Piwońska, Adam Szewczyk, Ullrich H Schröder, Klaus G Reymann, Iotr Bednarczy. Effectors of large-conductance calcium-activated potassium channel modulate glutamate excitotoxicity in organotypic hippocampal slice cultures. Acta neurobiologiae experimentalis. vol 76. issue 1. 2017-03-03. PMID:27102915. |
effectors of large-conductance calcium-activated potassium channel modulate glutamate excitotoxicity in organotypic hippocampal slice cultures. |
2017-03-03 |
2023-08-13 |
rat |
Marta Piwońska, Adam Szewczyk, Ullrich H Schröder, Klaus G Reymann, Iotr Bednarczy. Effectors of large-conductance calcium-activated potassium channel modulate glutamate excitotoxicity in organotypic hippocampal slice cultures. Acta neurobiologiae experimentalis. vol 76. issue 1. 2017-03-03. PMID:27102915. |
using organotypic hippocampal slice cultures exposed to glutamate, we demonstrated that preincubation of the slices with the bkca channel opener ns1619 resulted in decreased neuronal cell death measured as reduced uptake of propidium iodide. |
2017-03-03 |
2023-08-13 |
rat |
Luz M Suárez, María-Dolores Muñoz, Rafael Martín Del Río, José M Solí. Taurine content in different brain structures during ageing: effect on hippocampal synaptic plasticity. Amino acids. vol 48. issue 5. 2017-03-02. PMID:26803657. |
in the present study, using rats of three age groups (young, adult and aged) we determined whether the content of taurine and other amino acids (glutamate, serine, glutamine, glycine, alanine and gaba) was altered during ageing in different brain areas (cerebellum, cortex and hippocampus) as well non-brain tissues (heart, kidney, liver and plasma). |
2017-03-02 |
2023-08-13 |
rat |
Xiao Ze, Mingyu Su, Xiaoyang Zhao, Hao Jiang, Jie Hong, Xiaohong Yu, Dong Liu, Bingqing Xu, Lei Sheng, Qiuping Zhou, Junling Zhou, Jingwen Cui, Kai Li, Ling Wang, Yuguan Ze, Fashui Hon. TiO2 nanoparticle-induced neurotoxicity may be involved in dysfunction of glutamate metabolism and its receptor expression in mice. Environmental toxicology. vol 31. issue 6. 2017-03-01. PMID:25411160. |
in this study, mice were exposed to 1.25, 2.5, or 5 mg/kg body weight tio2 nps for 9 months, and the glutamate-glutamine cyclic pathway and expressions of glutamate receptors associated with the hippocampal neurotoxicity were investigated. |
2017-03-01 |
2023-08-13 |
mouse |
Xiao Ze, Mingyu Su, Xiaoyang Zhao, Hao Jiang, Jie Hong, Xiaohong Yu, Dong Liu, Bingqing Xu, Lei Sheng, Qiuping Zhou, Junling Zhou, Jingwen Cui, Kai Li, Ling Wang, Yuguan Ze, Fashui Hon. TiO2 nanoparticle-induced neurotoxicity may be involved in dysfunction of glutamate metabolism and its receptor expression in mice. Environmental toxicology. vol 31. issue 6. 2017-03-01. PMID:25411160. |
our findings showed elevations of glutamate release and phosphate-activated glutaminase activity, and reductions in glutamine and glutamine synthetase in the hippocampus following exposure to tio2 nps. |
2017-03-01 |
2023-08-13 |
mouse |
Xiao Ze, Mingyu Su, Xiaoyang Zhao, Hao Jiang, Jie Hong, Xiaohong Yu, Dong Liu, Bingqing Xu, Lei Sheng, Qiuping Zhou, Junling Zhou, Jingwen Cui, Kai Li, Ling Wang, Yuguan Ze, Fashui Hon. TiO2 nanoparticle-induced neurotoxicity may be involved in dysfunction of glutamate metabolism and its receptor expression in mice. Environmental toxicology. vol 31. issue 6. 2017-03-01. PMID:25411160. |
furthermore, tio2 nps significantly inhibited the expression of n-methyl-d-aspartate receptor subunits (including nr1, nr2a, and nr2b) and metabotropic glutamate receptor 2 in mouse hippocampus. |
2017-03-01 |
2023-08-13 |
mouse |
Xiao Ze, Mingyu Su, Xiaoyang Zhao, Hao Jiang, Jie Hong, Xiaohong Yu, Dong Liu, Bingqing Xu, Lei Sheng, Qiuping Zhou, Junling Zhou, Jingwen Cui, Kai Li, Ling Wang, Yuguan Ze, Fashui Hon. TiO2 nanoparticle-induced neurotoxicity may be involved in dysfunction of glutamate metabolism and its receptor expression in mice. Environmental toxicology. vol 31. issue 6. 2017-03-01. PMID:25411160. |
these findings suggest that the imbalance of glutamate metabolism triggered inhibitions of glutamate receptor expression in the tio2 np-exposed hippocampus. |
2017-03-01 |
2023-08-13 |
mouse |
Xiao-Fei Wang, Tai-Yun Zhao, Rui-Bin Su, Ning Wu, Jin L. Agmatine Prevents Adaptation of the Hippocampal Glutamate System in Chronic Morphine-Treated Rats. Neuroscience bulletin. vol 32. issue 6. 2017-02-27. PMID:27161447. |
agmatine prevents adaptation of the hippocampal glutamate system in chronic morphine-treated rats. |
2017-02-27 |
2023-08-13 |
rat |
Xiao-Fei Wang, Tai-Yun Zhao, Rui-Bin Su, Ning Wu, Jin L. Agmatine Prevents Adaptation of the Hippocampal Glutamate System in Chronic Morphine-Treated Rats. Neuroscience bulletin. vol 32. issue 6. 2017-02-27. PMID:27161447. |
the hippocampus is important for drug addiction; however, whether adaptation of glutamate neurotransmission is modulated by agmatine in the hippocampus remains unknown. |
2017-02-27 |
2023-08-13 |
rat |
Xiao-Fei Wang, Tai-Yun Zhao, Rui-Bin Su, Ning Wu, Jin L. Agmatine Prevents Adaptation of the Hippocampal Glutamate System in Chronic Morphine-Treated Rats. Neuroscience bulletin. vol 32. issue 6. 2017-02-27. PMID:27161447. |
here, we found that continuous pretreatment of rats with ascending doses of morphine for 5 days resulted in an increase in the hippocampal extracellular glutamate level induced by naloxone (2 mg/kg, i.p.) |
2017-02-27 |
2023-08-13 |
rat |
Xiao-Fei Wang, Tai-Yun Zhao, Rui-Bin Su, Ning Wu, Jin L. Agmatine Prevents Adaptation of the Hippocampal Glutamate System in Chronic Morphine-Treated Rats. Neuroscience bulletin. vol 32. issue 6. 2017-02-27. PMID:27161447. |
furthermore, in the hippocampal synaptosome model, agmatine decreased the release and increased the uptake of glutamate in synaptosomes from chronic morphine-treated rats, which might contribute to the reduced elevation of glutamate levels induced by agmatine. |
2017-02-27 |
2023-08-13 |
rat |
Xiao-Fei Wang, Tai-Yun Zhao, Rui-Bin Su, Ning Wu, Jin L. Agmatine Prevents Adaptation of the Hippocampal Glutamate System in Chronic Morphine-Treated Rats. Neuroscience bulletin. vol 32. issue 6. 2017-02-27. PMID:27161447. |
taken together, agmatine prevented the adaptation of the hippocampal glutamate system caused by chronic exposure to morphine, including modulating extracellular glutamate concentration and nmdar expression, which might be one of the mechanisms underlying the attenuation of opioid addiction by agmatine. |
2017-02-27 |
2023-08-13 |
rat |
Ali Siahposht-Khachaki, Zahra Fatahi, Asal Yans, Fariba Khodagholi, Abbas Haghparas. Involvement of AMPA/Kainate Glutamate Receptor in the Extinction and Reinstatement of Morphine-Induced Conditioned Place Preference: A Behavioral and Molecular Study. Cellular and molecular neurobiology. vol 37. issue 2. 2017-02-23. PMID:27053349. |
glutamate receptors in mesolimbic areas such as the nucleus accumbens, ventral tegmental area, prefrontal cortex (pfc), and hippocampus (hip) are a component of the mechanisms of drug-induced reward and can modulate the firing pattern of dopaminergic neurons in the reward system. |
2017-02-23 |
2023-08-13 |
rat |
José L Cechella, Marlon R Leite, Juliana T da Rocha, Fernando Dobrachinski, Bibiana M Gai, Félix A A Soares, Guilherme Bresciani, Luiz F F Royes, Gilson Zen. Caffeine suppresses exercise-enhanced long-term and location memory in middle-aged rats: Involvement of hippocampal Akt and CREB signaling. Chemico-biological interactions. vol 223. 2017-02-13. PMID:25260559. |
the [(3)h] glutamate uptake was reduced in hippocampus of rats administered with caffeine and submitted to swimming protocol. |
2017-02-13 |
2023-08-13 |
rat |
S O Vechkapova, T A Zapara, E A Morozova, A L Proskura, E E Schul'ts, T G Tolstikova, A S Ratushnya. Amide of Lambertian Acid Suppresses Hyperactivation of Inotropic Glutamate Receptors, but not Synaptic Potentiation in Hippocampal Sections. Bulletin of experimental biology and medicine. vol 161. issue 6. 2017-02-09. PMID:27783303. |
amide of lambertian acid suppresses hyperactivation of inotropic glutamate receptors, but not synaptic potentiation in hippocampal sections. |
2017-02-09 |
2023-08-13 |
Not clear |
S O Vechkapova, T A Zapara, E A Morozova, A L Proskura, E E Schul'ts, T G Tolstikova, A S Ratushnya. Amide of Lambertian Acid Suppresses Hyperactivation of Inotropic Glutamate Receptors, but not Synaptic Potentiation in Hippocampal Sections. Bulletin of experimental biology and medicine. vol 161. issue 6. 2017-02-09. PMID:27783303. |
amide of lambertian acid suppresses hyperactivation of inotropic glutamate receptors in hippocampal sections induced by a decrease in the level of magnesium ions (a selective blocker of glutamate nmda receptors). |
2017-02-09 |
2023-08-13 |
Not clear |
Haruna Tamano, Yukina Shakushi, Mitsugu Watanabe, Kazumi Ohashi, Chihiro Uematsu, Tadamune Otsubo, Kiyoshi Ikeda, Atsushi Taked. Preventive Effect of 3,5-dihydroxy-4-methoxybenzyl Alcohol (DHMBA) and Zinc, Components of the Pacific Oyster Crassostrea gigas, on Glutamatergic Neuron Activity in the Hippocampus. The Biological bulletin. vol 229. issue 3. 2017-01-24. PMID:26695827. |
the basal concentration of extracellular glutamate in the hippocampus was decreased under hippocampal perfusion with dhmba (1 mmol l(-1)) or zncl2 (μmol l(-1)), indicating that dhmba and zn(2+) suppress glutamatergic neuron activity under basal (static) conditions. |
2017-01-24 |
2023-08-13 |
mouse |