| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jingyu Zou, Min Wang, Osamu Uchiumi, Yuan Shui, Yasuhito Ishigaki, Xiaoyan Liu, Nobuyoshi Tajima, Takuya Akai, Hideaki Iizuka, Nobuo Kat. Learning impairment by minimal cortical injury in a mouse model of Alzheimer's disease. Brain research. vol 1637. 2017-01-24. PMID:26876740. |
hippocampal content of soluble aβ1-42 was increased in the glutamate 3xtg group. |
2017-01-24 |
2023-08-13 |
mouse |
| Yi Chang, Cheng Wei Lu, Tzu Yu Lin, Shu Kuei Huang, Su Jane Wan. Baicalein, a Constituent of Scutellaria baicalensis, Reduces Glutamate Release and Protects Neuronal Cell Against Kainic Acid-Induced Excitotoxicity in Rats. The American journal of Chinese medicine. vol 44. issue 5. 2017-01-17. PMID:27430911. |
this study evaluated the role of baicalein, a flavonoid compound isolated from the traditional chinese medicine scutellaria baicalensis, in glutamate release and glutamate neurotoxicity in the rat hippocampus. |
2017-01-17 |
2023-08-13 |
rat |
| Yi Chang, Cheng Wei Lu, Tzu Yu Lin, Shu Kuei Huang, Su Jane Wan. Baicalein, a Constituent of Scutellaria baicalensis, Reduces Glutamate Release and Protects Neuronal Cell Against Kainic Acid-Induced Excitotoxicity in Rats. The American journal of Chinese medicine. vol 44. issue 5. 2017-01-17. PMID:27430911. |
in the rat hippocampal nerve terminals (synaptosomes), baicalein inhibits depolarization-induced glutamate release, and this phenomenon is prevented by chelating the extracellular ca[formula: see text] ions and blocking presynaptic cav2.2 (n-type) and cav2.1 (p/q-type) channel activity. |
2017-01-17 |
2023-08-13 |
rat |
| Yi Chang, Cheng Wei Lu, Tzu Yu Lin, Shu Kuei Huang, Su Jane Wan. Baicalein, a Constituent of Scutellaria baicalensis, Reduces Glutamate Release and Protects Neuronal Cell Against Kainic Acid-Induced Excitotoxicity in Rats. The American journal of Chinese medicine. vol 44. issue 5. 2017-01-17. PMID:27430911. |
this study is the first to demonstrate that the natural compound baicalein inhibits glutamate release from hippocampal nerve terminals, and executes a protective action against kainic acid-induced excitotoxicity in vivo. |
2017-01-17 |
2023-08-13 |
rat |
| Ling Fan, Zhao Chen, Wenbin Fu, Nenggui Xu, Jianhua Liu, Aiping Lu, Ziping Li, Shengyong Su, Taixiang Wu, Aihua O. Soluble N-ethylmaleimide-sensitive Factor Attachment Receptor (SNARE) Protein Involved in the Remission of Depression by Acupuncture in Rats. Journal of acupuncture and meridian studies. vol 9. issue 5. 2017-01-17. PMID:27776762. |
moreover, no significance differences in glutamate content in the hippocampus were found among the riluzole+btx-a, acupuncture+btx-a and model groups (p>0.05). |
2017-01-17 |
2023-08-13 |
rat |
| Katsuyoshi Mizukami, Hiroyasu Akatsu, Eric E Abrahamson, Zhiping Mi, Milos D Ikonomovi. Immunohistochemical analysis of hippocampal butyrylcholinesterase: Implications for regional vulnerability in Alzheimer's disease. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 36. issue 2. 2017-01-09. PMID:26293308. |
since ca2/3 is generally considered more resistant to ad pathology, bche upregulation could impact the cholinergic modulation of glutamate neurotransmission to prevent/reduce neuronal excitotoxicity in ad hippocampus. |
2017-01-09 |
2023-08-13 |
Not clear |
| Mauricio P Cunha, Vicente Lieberknecht, Ana Belén Ramos-Hryb, Gislaine Olescowicz, Fabiana K Ludka, Carla I Tasca, Nelson H Gabilan, Ana Lúcia S Rodrigue. Creatine affords protection against glutamate-induced nitrosative and oxidative stress. Neurochemistry international. vol 95. 2017-01-09. PMID:26804444. |
in another set of experiments, the repeated, but not acute, administration of creatine (300 mg/kg, po) in mice prevented the decreases on cellular viability and mitochondrial membrane potential (assessed by tetramethylrhodamine ethyl ester, tmre, probe) of hippocampal slices incubated with glutamate (10 mm). |
2017-01-09 |
2023-08-13 |
mouse |
| Robert J Buchanan, Klevest Gjini, Pradeep Modur, Kevin T Meier, Zoltan Nadasdy, Jennifer L Robinso. In vivo measurements of limbic glutamate and GABA concentrations in epileptic patients during affective and cognitive tasks: A microdialysis study. Hippocampus. vol 26. issue 5. 2017-01-06. PMID:26606278. |
here, we report changes in the concentrations of the neurotransmitters glutamate (glu) and gamma-aminobutyric acid (gaba) in the hipp and the amg of patients with nonlesional temporal lobe epilepsy undergoing surgery for intracranial subdural and depth electrode implantation. |
2017-01-06 |
2023-08-13 |
human |
| Robert J Buchanan, Klevest Gjini, Pradeep Modur, Kevin T Meier, Zoltan Nadasdy, Jennifer L Robinso. In vivo measurements of limbic glutamate and GABA concentrations in epileptic patients during affective and cognitive tasks: A microdialysis study. Hippocampus. vol 26. issue 5. 2017-01-06. PMID:26606278. |
the performance of an emotion learning task (emolearn) was associated with a significant increase in the concentration of glutamate in the hipp when images with high valence content were processed, as compared to its concentration while processing images with low valence. |
2017-01-06 |
2023-08-13 |
human |
| Robert J Buchanan, Klevest Gjini, Pradeep Modur, Kevin T Meier, Zoltan Nadasdy, Jennifer L Robinso. In vivo measurements of limbic glutamate and GABA concentrations in epileptic patients during affective and cognitive tasks: A microdialysis study. Hippocampus. vol 26. issue 5. 2017-01-06. PMID:26606278. |
the processing of shapes on the other hand was accompanied with a significantly decreased concentration of the glutamate in the amg as well as in the hipp compared to the baseline. |
2017-01-06 |
2023-08-13 |
human |
| Mike Jones, Jun Wang, Shona Harmon, Beata Kling, Jörg Heilmann, John F Gilme. Novel Selective Butyrylcholinesterase Inhibitors Incorporating Antioxidant Functionalities as Potential Bimodal Therapeutics for Alzheimer's Disease. Molecules (Basel, Switzerland). vol 21. issue 4. 2017-01-03. PMID:27534722. |
the hybrid compounds were non-toxic to the murine hippocampal cell line ht-22 and lipoate esters were neuroprotective at 10 and 25 µm when the cells were challenged with glutamate (5 mm) in a similar manner to the positive control quercetin. |
2017-01-03 |
2023-08-13 |
Not clear |
| Jürgen Gallinat, Kibby McMahon, Simone Kühn, Florian Schubert, Martin Schaefe. Cross-sectional Study of Glutamate in the Anterior Cingulate and Hippocampus in Schizophrenia. Schizophrenia bulletin. vol 42. issue 2. 2017-01-02. PMID:26333842. |
cross-sectional study of glutamate in the anterior cingulate and hippocampus in schizophrenia. |
2017-01-02 |
2023-08-13 |
Not clear |
| Tharine Dal-Cim, Wagner C Martins, Daniel T Thomaz, Victor Coelho, Gabriela Godoy Poluceno, Débora Lanznaster, Samuel Vandresen-Filho, Carla I Tasc. Neuroprotection Promoted by Guanosine Depends on Glutamine Synthetase and Glutamate Transporters Activity in Hippocampal Slices Subjected to Oxygen/Glucose Deprivation. Neurotoxicity research. vol 29. issue 4. 2016-12-27. PMID:26858177. |
neuroprotection promoted by guanosine depends on glutamine synthetase and glutamate transporters activity in hippocampal slices subjected to oxygen/glucose deprivation. |
2016-12-27 |
2023-08-13 |
Not clear |
| Tharine Dal-Cim, Wagner C Martins, Daniel T Thomaz, Victor Coelho, Gabriela Godoy Poluceno, Débora Lanznaster, Samuel Vandresen-Filho, Carla I Tasc. Neuroprotection Promoted by Guanosine Depends on Glutamine Synthetase and Glutamate Transporters Activity in Hippocampal Slices Subjected to Oxygen/Glucose Deprivation. Neurotoxicity research. vol 29. issue 4. 2016-12-27. PMID:26858177. |
in this study, a putative effect of guo action on glutamate transporters activity modulation was assessed in hippocampal slices subjected to oxygen and glucose deprivation (ogd), an in vitro model of brain ischemia. |
2016-12-27 |
2023-08-13 |
Not clear |
| Tharine Dal-Cim, Wagner C Martins, Daniel T Thomaz, Victor Coelho, Gabriela Godoy Poluceno, Débora Lanznaster, Samuel Vandresen-Filho, Carla I Tasc. Neuroprotection Promoted by Guanosine Depends on Glutamine Synthetase and Glutamate Transporters Activity in Hippocampal Slices Subjected to Oxygen/Glucose Deprivation. Neurotoxicity research. vol 29. issue 4. 2016-12-27. PMID:26858177. |
altogether, results in hippocampal slices subjected to ogd show that guo counteracts the release of excitatory amino acids, stimulates the activity of gs, and decreases the cellular damage by modulation of glutamate transporters activity. |
2016-12-27 |
2023-08-13 |
Not clear |
| Kuan Ming Chiu, Cheng Wei Lu, Ming Yi Lee, Ming Jiuh Wang, Tzu Yu Lin, Su Jane Wan. Neuroprotective and anti-inflammatory effects of lidocaine in kainic acid-injected rats. Neuroreport. vol 27. issue 7. 2016-12-20. PMID:26999361. |
given the involvement of glutamate neurotoxicity in the pathogenesis of various neurological disorders, this study investigated the role of lidocaine in hippocampal neuronal death and inflammatory events induced by an i.p. |
2016-12-20 |
2023-08-13 |
rat |
| Pernille Bøttger, Simon Glerup, Bodil Gesslein, Nina B Illarionova, Toke J Isaksen, Anders Heuck, Bettina H Clausen, Ernst-Martin Füchtbauer, Jan B Gramsbergen, Eli Gunnarson, Anita Aperia, Martin Lauritzen, Kate L Lambertsen, Poul Nissen, Karin Lykke-Hartman. Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model. Scientific reports. vol 6. 2016-12-19. PMID:26911348. |
in vitro studies showed impaired glutamate uptake in hippocampal mixed astrocyte-neuron cultures from α2(g301r/g301r) e17 embryonic mice, and moreover, induction of cortical spreading depression (csd) resulted in reduced recovery in α2(+/g301r) male mice. |
2016-12-19 |
2023-08-13 |
mouse |
| Ery Hermawati, Dwi Cahyani Ratna Sari, Ginus Partadiredj. The effects of black garlic ethanol extract on the spatial memory and estimated total number of pyramidal cells of the hippocampus of monosodium glutamate-exposed adolescent male Wistar rats. Anatomical science international. vol 90. issue 4. 2016-12-13. PMID:25422084. |
monosodium glutamate (msg) is believed to exert deleterious effects on various organs, including the hippocampus, likely via the oxidative stress pathway. |
2016-12-13 |
2023-08-13 |
rat |
| Fernanda Hansen, Cíntia Eickhoff Battú, Márcio Ferreira Dutra, Fabiana Galland, Franciane Lirio, Núbia Broetto, Patrícia Nardin, Carlos-Alberto Gonçalve. Methylglyoxal and carboxyethyllysine reduce glutamate uptake and S100B secretion in the hippocampus independently of RAGE activation. Amino acids. vol 48. issue 2. 2016-12-13. PMID:26347375. |
methylglyoxal and carboxyethyllysine reduce glutamate uptake and s100b secretion in the hippocampus independently of rage activation. |
2016-12-13 |
2023-08-13 |
Not clear |
| Kazunori Sato, Yuki Yamanaka, Yasuharu Asakura, Taku Nedach. Glutamate levels control HT22 murine hippocampal cell death by regulating biphasic patterns of Erk1/2 activation: role of metabolic glutamate receptor 5. Bioscience, biotechnology, and biochemistry. vol 80. issue 4. 2016-12-13. PMID:26539627. |
glutamate levels control ht22 murine hippocampal cell death by regulating biphasic patterns of erk1/2 activation: role of metabolic glutamate receptor 5. |
2016-12-13 |
2023-08-13 |
Not clear |